To be mindful of the breath or pain: Comparing two brief preoperative mindfulness techniques for total joint arthroplasty patients
Open accessAbstract
OBJECTIVE: Total joint arthroplasty (TJA) often reduces pain and improves function, but it is also a risk factor for the development of chronic pain and postoperative opioid use. To protect against these untoward postsurgical outcomes, TJA patients need better, non-pharmacological pain management strategies. This study compared two, promising, mindfulness-based pain management techniques. METHOD: We conducted a single-site, three-arm, parallel-group randomized controlled study conducted at an orthopedic clinic among patients undergoing TJA of the knee or hip. TJA patients (N = 118, M age = 65, female = 73, Caucasian = 110) were randomized to either a preoperative mindfulness of breath (MoB), mindfulness of pain (MoP), or cognitive-behavioral pain psychoeducation (CB) intervention, approximately 3 weeks before surgery. Each intervention was delivered in a single, 20-min session during a 2-hr, preoperative education program. Change in pain intensity was the sole preoperative outcome. The postoperative outcomes, pain intensity, pain interference, and opioid use were assessed on the 2nd, 3rd, 7th, 14th, 21st, and 28th postoperative days. RESULTS: MoB was found to most effectively decrease preoperative pain scores, F(2, 89) = 5.28, p = .007, while MoP resulted in the least amount of postoperative pain intensity, F(8, 94) = 3.21, p = .003, and interference, F(8, 94) = 2.52, p = .016). Both MoB and MoP decreased postoperative opioid use relative to CB, F(8, 83) = 16.66, p < .001. CONCLUSION: A brief preoperative MBI may be able to prevent both postoperative pain and opioid use. Moreover, the MBIs used in this study are highly feasible, capable of being delivered by nearly any healthcare provider, and requiring minimal clinic time given their brevity. As such, embedding MBIs in surgical care pathways has considerable potential. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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Interpersonal mindfulness-based interventions conducted in group formats have shown positive outcomes, such as increased social connectedness and reductions in psychopathological symptoms.
“Interpersonal MBIs conducted in group formats have also shown positive outcomes, such as increased social connectedness and reductions in psychopathological symptoms [37,38,39].”
From 10-Week Trajectories of Candidate Psychological Processes Differentially Predict Mental Health Gains from Online Dyadic versus Mindfulness Interventions: A Randomized Clinical Trial (2024) · cites this paper as [37]
The Methods > Interventions passage describes brief, single-session mindfulness techniques for managing surgical pain, and the Results > Path Model passage reports pain outcomes. Searches for interpersonal mindfulness, group-format delivery, social connectedness, and psychopathological symptoms found no passage addressing the attributed claim. The available passages have no page numbers. (LLM, conf=0.76)
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BackgroundPester, B., Wilson, J. M., Yoon, J., Lazaridou, A., Schreiber, K. L., Cornelius, M. C., Campbell, C. M., Smith, M. T., Haythornthwaite, J. A., Edwards, R. R., et al. (2022) · Pain Medicine · doi:10.1093/pm/pnac183 · Cited by 28 · see citing works
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“This result is inconsistent with findings from three previously published RCTS of brief, preoperative MBIs for TJA patients (Dindo et al., 2018; Hanley et al., 2021a, b).”
ResultRoberts, R. L., Hanley, A. W., & Garland, E. L. (2022) · The American Surgeon · doi:10.1177/00031348221114019 · Cited by 19 · see citing works
“Similar to previous fi ndings, 38 the different styles of mindfulness practice appeared to have distinct therapeutic bene fi ts. Mindfulness of breathing resulted in greater acute pre-operative pain relief, and mindfulness of pain was associated with reduced medication desire.”
ResultGarland, E. L., Roberts, R. L., Hanley, A. W., Zeidan, F. Z., & Keefe, F. J. (2022) · Mindfulness · doi:10.1007/s12671-022-02034-y · Cited by 13 · see citing works
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“Likewise, a brief 15-min mindfulness induction focusing on breathing had a positive effect on decentering, which in turn, reduced ratings in pain, desire for pain medication, and anxiety among orthopedic surgery patients (e.g., Hanley et al., 2021).”
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“One study showed mindful breathing showed positive impact for reduced opioid use at 1 month 28 ; another showed a digital skills-based intervention improved time to opioid cessation after breast cancer surgery 24 ; and the Hadlands-myth et al showed four brief sessions of pain self-management…”
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“PO outcomesDuration of intervention(s) Intervention(s)Patients, N SurgeryStudy designReference MoP decreased PO pain intensity and interference; MoB and MoP decreased PO opioid use One 20-min session 3 weeks before surgery MFa of breath (MoB), MF of pain (MoP), or CBb pain psychoeducation 118Total joint arthroplasty R…”
BackgroundInfluentialMarch, M. K., Harmer, A. R., Thomas, B., Maitland, A. E., Black, D. A., & Dennis, S. M. (2022) · Arthroplasty · doi:10.1186/s42836-022-00128-5 · Cited by 11 · see citing works
“A majority of psychological interventions in that study were based on cognitivebehavioral methods, which achieved mixed results [72, 73], however, positive effects on TKA outcomes have been shown with mindfulness-based therapy [56, 74].”
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“A larger, three-arm RCT (N=118) tested the effects of two mindfulness approaches for patients undergoing total joint arthroplasty: mindfulness of breath (MoB) and mindfulness of pain (MoP) [63].”
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“16,17”
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“However, more recently, brief MBI delivered in the preoperative period have demon - strated medium to large effects on TJA patients’ acute pain and pain medication desire (Hanley et al., 2021a, b), while also improving postoperative outcomes.”
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“…of Physical Medicine and Rehabilitation, University of Utah, Salt Lake City, USA Keywords Mindfulness · Exercise · Cancer · Self-transcendence · Brief intervention 1 3 Mindfulness (2023) 14:1804–1812 only a single session (e.g., Dindo et al., 2018; Garland et al., 2017; Hanley et al., 2021a, b, c).”
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“Interpersonal MBIs conducted in group formats have also shown positive outcomes, such as increased social connectedness and reductions in psychopathological symptoms [37–39].”
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“Alternatives include centralizing group-delivered MBIs across sites or initiating a group-delivered MBI before surgery, similar to preoperative educational sessions in patients undergoing total joint surgery, 57,58 and then offering drop-in sessions after surgery.”
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“However, emerging evidence suggests being mindful of pain, itself, may have therapeutic value, 13,15 which is why Study 3 combined mindful breathing instruction with mindfulness of pain instruction.”
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Effect of virtual walk in green or urban spaces on pain perception among healthy adults
Mucha, A., Pollak, A. M., & Wojtyna, E. (2025) · Scientific Reports · doi:10.1038/s41598-025-12911-w · Cited by 3 · see citing works
“Given the existing literature suggesting that there may be variations in pain tolerance thresholds caused by high temperatures between women and men 59 , future studies should take a closer look at gender differences.”
Bui, T., Dooley, M. J., Bell, J. S., & Myles, P. S. (2025) · BJA Open · doi:10.1016/j.bjao.2025.100509 · Cited by 3 · see citing works
Effects of Mindfulness on Postoperative Pain, Anxiety, and Opioid Use: An Integrative Review
Miller, M. A., Ye, L., van Pelt, M., & Pavone, K. J. (2025) · Pain Management Nursing · doi:10.1016/j.pmn.2025.04.004 · Cited by 3 · see citing works
Martorella, G., Hanley, A. W., & Muessig, K. E. (2025) · JMIR Nursing · doi:10.2196/69010 · Cited by 2 · see citing works
“Brief MBIs delivered preoperatively have been shown to have medium to large effects on orthopedic surgical patients’ acute pain, pain unpleasantness, opioid use, and pain medication desire [19,20].”
Scoping Review of Psychological Therapies in Acute Pain Relief—To Whom, From Who, and Which Channels
Tololiu, K. E., Kurnianto, A. A., Kusuma, I. Y., Ehlers, J. S., Deák, A., Kocsor, F., & Csókási, K. (2025) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2025.03.005 · Cited by 2 · see citing works
Hanley, A. W., Coleman, C., Davis, A., Sorkpor, S. K., Gililland, J. M., & Zgierska, A. E. (2025) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-24-01375 · Cited by 2 · see citing works
Designing a Perioperative Mind-Body Intervention for Peripheral Vascular Interventions
Png, C. Y. M., Mehta, D. H., Dua, A., Stephen, A. E., Bruce, A. M., Forsythe, A., Chitilian, H. V., Bringle, E. J., Simpson, J. C., Parady, K. M., et al. (2024) · Global Advances in Integrative Medicine and Health · doi:10.1177/27536130241285129 · Cited by 2 · see citing works
Hanley, A. W., Davis, A., Worts, P. R., & Pratscher, S. D. (2025) · Journal of Behavioral Medicine · doi:10.1007/s10865-024-00548-5 · Cited by 2 · see citing works
“…wellness center given an 8-minute, audio-recorded, mindful breathing intervention reported less pain intensity before their provider visit began and greater treatment satisfaction at their visit’s end relative to controls (Hanley et al., 2024; Hanley, Garland, & Zin-Hanley et al., 2021a, b, c).”
Ugarte, D. A., Hanley, A. W., Dusek, J. A., Martin, S. R., Cumberland, W. G., & Young, S. D. (2023) · Cureus · doi:10.7759/cureus.35073 · Cited by 2 · see citing works
“Although Mini MORE has been acceptable to other clinical populations [16-18] and was found to be acceptable in this pilot study, interviewing PWSCD exposed to Mini MORE will provide important insights into how to adapt Mini MORE for PWSCD better.”
BackgroundMethodResultMindfulness in Facilitating Pelvic Floor Botulinum Toxin Injection in Women with Chronic Pelvic Pain
Aredo, J. V., Tandon, H. K., Panahi, S., Phan, V. T., Ameli, R., Karp, B. I., & Stratton, P. (2024) · Toxins · doi:10.3390/toxins16050216 · Cited by 1 · see citing works
Finan, P. H., Tsang, S., Cherup, N. P., Abraham, L., Reid, M. J., Yaden, D. B., & Smith, M. T. (2025) · Journal of Pain · doi:10.1016/j.jpain.2025.105598 · Cited by 1 · see citing works
Young, S. D., & Hanley, A. W. (2025) · European Journal of Investigation in Health Psychology and Education · doi:10.3390/ejihpe15120239 · Cited by 1 · see citing works
Hodren, N., Williamson, T., & Shires, A. G. (2025) · Mindfulness · doi:10.1007/s12671-025-02712-7 · Cited by 1 · see citing works
“…of pain, reliance on pain medications, pain self-efficacy, and psychological distress, and have been rated as acceptable by participants (Cayoun et al., 2020; Hanley et al., 2021, 2023; Howarth et al., 2019; McClintock et al., 2019; Mehling et al., 2024; Shires et al., 2019; Strigo et al., 2024).”
Kim, T. K. (2021) · Clinical Orthopaedics and Related Research · doi:10.1097/corr.0000000000002029 · Cited by 1 · see citing works
Bellieni, C. V. (2022) · Springer eBooks · doi:10.1007/978-3-030-96256-2_18 · Cited by 1 · see citing works
Designing a Perioperative Mind-Body Intervention for Peripheral Vascular InterventionsPreprint
Png, C. Y. M., Mehta, D. H., Dua, A., Stephen, A. E., Bruce, A. M., Forsythe, A., Chitilian, H. V., Bringle, E. J., Simpson, J. C., Parady, K. M., et al. (2024) · medRxiv · doi:10.1101/2024.06.07.24308071
Cooperman, N. A., Shen, J., Gordon, A. J., & Garland, E. L. (2024) · Substance use & addiction journal · doi:10.1177/29767342241261890
İnam, Ö., & Satılmış, İ. G. (2024) · doi:10.2196/preprints.64220
Martorella, G., Hanley, A. W., & Muessig, K. E. (2024) · doi:10.2196/preprints.69010
Aziz, M., Iftikhar, M., Haider, S., Siddique, S., Barkat, M., Munawar, S., Ejaz, M., & Ahsan, S. (2025) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v6i4.2450
Amorim, A. B., Gianola, M., Barrows, D., & Zeidan, F. Z. (2025) · Pain · doi:10.1097/j.pain.0000000000003832
Hanley, A. W., Gibson, R. W., Davis, A., Stecher, C. D., Childs, K., & Worts, P. R. (2025) · International Journal of Behavioral Medicine · doi:10.1007/s12529-025-10398-3
“Brief, single-session MBIs (i.e., 20 min) delivered in medical settings have reliably reduced acute pain [24–27].”
Prevention and Treatment of Postsurgical Pain
Wilson, J. M., Schreiber, K. L., Edwards, R. R., & Meints, S. M. (2025) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2025.08.006
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Childs, K., Minnick, C., Martorella, G., & Hanley, A. W. (2026) · JMIR Research Protocols · doi:10.2196/82362
“…relative to the psycho-education control group, which in turn predicted immediate pain relief and improved postoperative outcomes, including reduced pain intensity and interference during the first month after surgery and better physical functioning 6 weeks after surgery [21,25,26].”
Kim, S., & Darnall, B. D. (2026) · Anesthesiology · doi:10.1097/aln.0000000000005912
Sun, L., Sun, X., Zhang, Z., & Zhang, X. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1748747
“In recent years, breathing techniques have been used in the clinic to alleviate these symptoms as an adjunct therapy (18, 19).”
Egan, W. E., Crane, P. J., Morris, J., Young, J. L., & Rhon, D. I. (2026) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2026.2656341
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“Brief mindfulness-based training regimens, consisting of three to six sessions, can also reduce cLBP [20 – 22].”
Majumdar, J. R., Zakhari, R., Caramore, A., O’Leary, J., Campbell, J., & O’Connor, M. (2026) · doi:10.2196/preprints.108477
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- Authors
- Hanley, A. W., Gililland, J., & Garland, E. L.
- Affiliations
- University of Utah (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2021-07
- Volume
- 89
- Issue
- 7
- Pages
- 590-600
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC8363593
- OpenAlex
- W3175471757
- Cited by
- 63
- References
- 48
- Citations by year
- 2026: 7 · 2025: 18 · 2024: 18 · 2023: 6 · 2022: 9 · 2021: 5
- FWCI
- 6.48
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Universty of Utah College of Social Work
- National Institutes of Health (R01DA042033)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
- Health Sciences › Medicine › Surgery › Total Knee Arthroplasty Outcomes
- Keywords
- mindfulness-based interventions, total joint arthroplasty, preoperative analgesia, postoperative pain, opioid use, pain interference, knee arthroplasty, total hip arthroplasty, non-pharmacological pain management
- MeSH terms
- Aged, Analgesics, Opioid, Arthroplasty, Female, Humans, Male, Postoperative Pain, Preoperative Care, Psychotherapy, Brief, Mindfulness
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