A controlled trial of adaptive disclosure- enhanced to improve functioning and treat posttraumatic stress disorder
Open accessAbstract
OBJECTIVE: This is a randomized controlled trial (NCT03056157) of an enhanced adaptive disclosure (AD) psychotherapy compared to present-centered therapy (PCT; each 12 sessions) in 174 veterans with posttraumatic stress disorder (PTSD) related to traumatic loss (TL) and moral injury (MI). AD employs different strategies for different trauma types. AD-Enhanced (AD-E) uses letter writing (e.g., to the deceased), loving-kindness meditation, and bolstered homework to facilitate improved functioning to repair TL and MI-related trauma. METHOD: The primary outcomes were the Sheehan Disability Scale (SDS), evaluated at baseline, throughout treatment, and at 3- and 6-month follow-ups (Brief Inventory of Psychosocial Functioning was also administered), the Clinician-Administered PTSD Scale (CAPS-5), the Dimensions of Anger Reactions, the Revised Conflict Tactics Scale, and the Quick Drinking Screen. RESULTS: There were statistically significant between-group differences on two outcomes: The intent-to-treat (ITT) mixed-model analysis of SDS scores indicated greater improvement from baseline to posttreatment in the AD-E group (d = 2.97) compared to the PCT group, d = 1.86; -2.36, 95% CI [-3.92, -0.77], t(1,510) = -2.92, p < .001, d = 0.15. Twenty-one percent more AD-E cases made clinically significant changes on the SDS than PCT cases. From baseline to posttreatment, AD-E was also more efficacious on the CAPS-5 (d = 0.39). These differential effects did not persist at follow-up intervals. CONCLUSION: This was the first psychotherapy of veterans with TL/MI-related PTSD to show superiority relative to PCT with respect to functioning and PTSD, although the differential effect sizes were small to medium and not maintained at follow-up. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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Open and controlled trials of Adaptive Disclosure and AD-enhanced protocols report improvements in PTSD symptoms, depression, and functioning consistent with proposed processes, although formal mediation analyses remain limited.
“Open and controlled trials of AD and AD-enhanced protocols report improvements in PTSD symptoms, depression, and functioning consistent with these proposed processes, although formal mediation analyses remain limited (90, 91).”
From The therapeutic role of self-transcendence in moral injury recovery: theory, mechanisms, and clinical implications (2026) · cites this paper as [90]
The paper’s account of earlier AD trials reports improvements in PTSD and depression and functional change (passage 1, section labeled Abstract > Conclusion; page unavailable). Its Results report improved PTSD symptoms and functioning with AD-E (passages 4–5; page unavailable). The Discussion says questions remain about the individual change agents, but our copy does not explicitly establish that formal mediation analyses across these trials are limited or that the observed improvements followed the proposed processes. (LLM, conf=0.84)
Experimental — accuracy not yet measuredAdaptive Disclosure methods were designed to expand moral and relational perspectives and challenge shame-based self-appraisals by situating morally painful experiences within broader compassionate frameworks, thereby engaging processes consistent with self-transcendence.
“Clinically, these methods were designed, in part, to expand moral and relational perspectives and to challenge shame-based self-appraisals by situating morally painful experiences within broader, more compassionate relational and contextual frameworks, thereby engaging processes consistent with self-transcendence (90).”
From The therapeutic role of self-transcendence in moral injury recovery: theory, mechanisms, and clinical implications (2026) · cites this paper as [90]
The treatment description in our copy (page unavailable) says Adaptive Disclosure uses dialogue with a compassionate moral authority to challenge guilt, shame, and condemnation of self and others. It also describes changing beliefs about personal and collective humanity. The copy does not identify these methods as engaging self-transcendence, so that final characterization remains an interpretation rather than a finding attributed to the source. (LLM, conf=0.82)
Experimental — accuracy not yet measuredMoral repair-oriented interventions like Adaptive Disclosure use imaginal dialogue and perspective-taking to promote movement from rigid, self-condemning narratives toward more expansive, contextualized accounts, which conceptually overlap with self-transcendence-related perspective shifting and mindful positive reappraisal.
“Moral repair–oriented interventions like Adaptive Disclosure use imaginal dialogue and perspective-taking to promote movement from rigid, self-condemning narratives toward more expansive, contextualized accounts (31, 90), which conceptually overlap with ST-related perspective shifting and mindful positive reappraisal (33, 36, 65).”
From The therapeutic role of self-transcendence in moral injury recovery: theory, mechanisms, and clinical implications (2026) · cites this paper as [90]
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Cited by
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Moral injury: An overview of conceptual, definitional, assessment, and treatment issues
Litz, B. T., & Walker, H. E. (2025) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-081423-022604 · Cited by 73 · see citing works
Self-citationMoral injury prevention and intervention
Williamson, V., Kothari, R., Bonson, A., Campbell, G., Greenberg, N., Murphy, D., & Lamb, D. (2025) · European Journal of Psychotraumatology · doi:10.1080/20008066.2025.2567721 · Cited by 16 · see citing works
Fleming, W. H. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1701564
“Open and controlled trials of AD and AD-enhanced protocols report improvements in PTSD symptoms, depression, and functioning consistent with these proposed processes, although formal mediation analyses remain limited (90, 91).”
- Authors
- Litz, B. T., Yeterian, J., Berke, D., Lang, A. J., Gray, M. J., Nienow, T., Frankfurt, S., Harris, J. I., Maguen, S., & Rusowicz-Orazem, L.
- Affiliations
- VA Boston Healthcare System (US)
- VA Connecticut Healthcare System (US)
- Hunter College (US)
- VA San Diego Healthcare System (US)
- University of Wyoming (US)
- Minneapolis VA Health Care System (US)
- VA Heart of Texas Health Care Network (US)
- San Francisco VA Health Care System (US)
- Boston University (US)
- ORCID
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2024-03
- Volume
- 92
- Issue
- 3
- Pages
- 150-164
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC11771448
- OpenAlex
- W4391867066
- Cited by
- 25
- References
- 0
- Citations by year
- 2026: 13 · 2025: 8 · 2024: 4
- FWCI
- 12.53
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- U.S. Department of Veterans Affairs (5I01RX002135)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- post-traumatic stress disorder, moral injury, traumatic loss, veterans, present-centered therapy, letter writing, loving-kindness meditation, psychosocial functioning, disability, anger, conflict tactics, alcohol consumption, trauma-focused psychotherapy
- MeSH terms
- Humans, Psychotherapy, Stress Disorders, Post-Traumatic, Databases, Factual, Disclosure, Intention
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