Cited by 51Sexual Differentiation and DisordersGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesAdrenal Hormones and Disorders

Absence of response to dihydrotestosterone in the syndrome of testicular feminization

STRICKLAND, ALVA L., FRENCH, FRANK S.·1969·The Journal of Clinical Endocrinology & Metabolism

Abstract

ALVA L. STRICKLAND, FRANK S. FRENCH; Absence of Response to Dihydrotestosterone in the Syndrome of Testicular Feminization, The Journal of Clinical Endocri

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Crossref · 10.1210/jcem-29-9-1284

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  • Athletes with CAIS can compete fairly as females because the circulating testosterone, although at adult male levels, has no physiological effect, so that affected individuals are indistinguishable from females and gain no benefits of the sex difference arising from unimpeded testosterone action.

    “Athletes with CAIS can compete fairly as females because the circulating testosterone, although at adult male levels, has no physiological effect so that, in terms of androgen action and the ensuing physical somatic advantages of male sex, affected individuals are indistinguishable from females and gain no benefits of the sex difference arising from unimpeded testosterone action.”

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Authors
STRICKLAND, A. L., & FRENCH, F. S.
Affiliations
University of North Carolina at Chapel Hill (US)
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1969-09
Volume
29
Issue
9
Pages
1284-1286
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2002416891
Cited by
50
References
0
Citations by year
2018: 1
FWCI
3.38
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
androgen insensitivity syndrome, dihydrotestosterone, 5-alpha-reductase deficiency, androgen receptor
MeSH terms
Adult, Androstanes, Castration, Citrates, Female, Humans, Hydroxysteroid Dehydrogenases, Nitrogen, Phosphorus, Disorders of Sex Development, Dihydrotestosterone, Sterols, Androgen-Insensitivity Syndrome, Testosterone

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