Evidence for translation of rabbit globin mRNA after liposomemediated insertion into a human cell line
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In 1978, protein expression was induced in human cells after liposomal mRNA transport.
“In the same year, protein expression was also induced in human cells after liposomal mRNA transport.18”
From COVID-19 mRNA vaccines: Platforms and current developments (2022) · cites this paper as [18]
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- Authors
- OSTRO, M. J., GIACOMONI, D., LAVELLE, D., PAXTON, W., & DRAY, S.
- Affiliations
- University of Illinois Chicago (US)
- Venue
- Nature
- Published
- 1978-08
- Volume
- 274
- Issue
- 5674
- Pages
- 921-923
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1988395837
- Cited by
- 154
- References
- 24
- Citations by year
- 2026: 8 · 2025: 23 · 2024: 19 · 2023: 19 · 2022: 16 · 2021: 4 · 2014: 1 · 2013: 1 · 2012: 2
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- rabbit globin mRNA, mRNA translation, liposome encapsulation, HEp-2 cells, protein synthesis
- MeSH terms
- Amanitins, Antigen-Antibody Complex, Biological Transport, Cell Line, Dactinomycin, Globins, Liposomes, RNA, Messenger, Protein Biosynthesis
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