Translation of rabbit globin mRNA introduced by liposomes into mouse lymphocytes
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Development of protective lipid-based formulations made subsequent mRNA research pursuits less complex.
“However, the development of protective lipid-based formulations, which were first successfully used in 1978 in a study where rabbit reticulocyte 9S mRNA was introduced into mouse lymphocytes, resulting in globin synthesis,17 made subsequent mRNA research pursuits less complex.”
From COVID-19 mRNA vaccines: Platforms and current developments (2022) · cites this paper as [17]
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- Authors
- DIMITRIADIS, G. J.
- Affiliations
- National Institute for Medical Research (GB)
- Corresponding author
- DIMITRIADIS, GIORGOS J.
- Venue
- Nature
- Published
- 1978-08
- Volume
- 274
- Issue
- 5674
- Pages
- 923-924
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2083665908
- Cited by
- 212
- References
- 23
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 31 · 2023: 29 · 2022: 26 · 2021: 12 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 1 · 2014: 1 · 2012: 2
- FWCI
- 5.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- The Mouseion at the JAXlibrary (Jackson Laboratory) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Keywords
- rabbit globin mRNA, mRNA translation, ribosome assembly, liposome fusion
- MeSH terms
- Animals, Globins, Liposomes, Lymphocytes, Rabbits, RNA, Messenger, Species Specificity, Spleen, Protein Biosynthesis, Mice
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