Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells
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circRNA was first identified in 1976 and later detected in human cells.
“circRNA was first identified in 197646 and was later detected in human cells.47”
From COVID-19 mRNA vaccines: Platforms and current developments (2022) · cites this paper as [47]
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The biogenesis, biology and characterization of circular RNAs
Kristensen, L. S., Andersen, M. S., Stagsted, L. V. W., Ebbesen, K. K., Hansen, T. B., & Kjems, J. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0158-7 · Cited by 4,823 · see citing works
Exon-intron circular RNAs regulate transcription in the nucleus
Li, Z., Huang, C., Bao, C., Chen, L., Lin, M., Wang, X., Zhong, G., Yu, B., Hu, W., Dai, L., et al. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2959 · Cited by 2,905 · see citing works
Circular RNA: a new star of noncoding RNAs
Qu, S., Yang, X., Li, X., Wang, J., Gao, Y., Shang, R., Sun, W., Dou, K., & Li, H. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.06.003 · Cited by 1,808 · see citing works
COVID-19 mRNA vaccines: Platforms and current developments
Szabó, G. T., Mahiny, A. J., & Vlatkovic, I. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.02.016 · Cited by 308 · see citing works
Role of circular RNAs in brain development and CNS diseases
Mehta, S. L., Dempsey, R. J., & Vemuganti, R. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101746 · Cited by 281 · see citing works
Insights into the biogenesis and potential functions of exonic circular RNA
Ragan, C., Goodall, G. J., Shirokikh, N. E., & Preiss, T. (2019) · Scientific Reports · doi:10.1038/s41598-018-37037-0 · Cited by 137 · see citing works
The circular RNome of primary breast cancer
Smid, M., Wilting, S. M., Uhr, K., Rodríguez-González, F. G., de Weerd, V., Prager-Van der Smissen, W. J. C., van der Vlugt-Daane, M., van Galen, A., Nik-Zainal, S., Butler, A., et al. (2019) · Genome Research · doi:10.1101/gr.238121.118 · Cited by 105 · see citing works
Circular RNAs in depression: Biogenesis, function, expression, and therapeutic potential
Gan, H., Lei, Y., Yuan, N., Tang, K., Hao, W., Ma, Q., Wu, M., Zhou, X., Li, X., Huang, J., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111244 · Cited by 41 · see citing works
Noncoding RNA: from dark matter to bright star
Xue, Y., Chen, R., Qu, L., & Cao, X. (2020) · Science China Life Sciences · doi:10.1007/s11427-020-1676-5 · Cited by 38 · see citing works
- Authors
- HSU, M.-T., & COCA-PRADOS, M.
- Affiliations
- Rockefeller University (US)
- Venue
- Nature
- Published
- 1979-07
- Volume
- 280
- Issue
- 5720
- Pages
- 339-340
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2024248021
- Cited by
- 1,021
- References
- 0
- Citations by year
- 2026: 28 · 2025: 78 · 2024: 99 · 2023: 125 · 2022: 135 · 2021: 155 · 2020: 116 · 2019: 96 · 2018: 66 · 2017: 46 · 2016: 22 · 2015: 13 · 2014: 2 · 2013: 7 · 2012: 1
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Circular RNAs in diseases
- Keywords
- circular RNA, single-stranded RNA, RNA conformation, RNA viruses, RNA base pairing, cytoplasmic RNA, eukaryotic cells, RNA secondary structure
- MeSH terms
- Cells, Cytoplasm, Eukaryotic Cells, HeLa Cells, Humans, RNA
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