Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 450

The DOI matches its Crossref record.

Genetic evidence for a higher female migration rate in humans.

Seielstad, Mark T., Minch, Eric, Cavalli-Sforza, L. Luca·1998·Nature Genetics
DOI 10.1038/3088
Open this paper in CoChat — free account

Abstract

Mitochondrial DNA and the Y chromosome have been used extensively in the study of modern human origins and other phylogenetic questions, but not in the context of their sex-specific modes of transmission. mtDNA is transmitted exclusively by females, whereas the Y chromosome is passed only among males. As a result, differences in the reproductive output or migration rate of males and females will influence the geographic patterns and relative level of genetic diversity on the Y chromosome, autosomes and mtDNA (ref. 1). We have found that Y chromosome variants tend to be more localized geographically than those of mtDNA and the autosomes. The fraction of variation within human populations for Y chromosome single nucleotide polymorphisms (SNPs) is 35.5%, versus 80-85% for the autosomes and mtDNA (refs 6-8). A higher female than male migration rate (via patrilocality, the tendency for a wife to move into her husband's natal household) explains most of this discrepancy, because diverse Y chromosomes would enter a population at a lower rate than mtDNA or the autosomes. Polygyny may also contribute, but the reduction of variation within populations that we measure for the Y chromosome, relative to the autosomes and mitochondrial DNA, is of such magnitude that differences in the effective population sizes of the sexes alone are insufficient to produce the observation.

Overview

Integrity signals

Registry

Crossref · 10.1038/3088

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 30

  1. Salem, A.H., Badr, F.M., Gaballah, M.F. & Paabo, S. The genetics of traditional living: Y-chromosomal and mitochondrial lineages in the Sinai Peninsula. Am. J. Hum. Genet. 59, 741–743 (1996).
  2. Seielstad, M.T. et al. Construction of human Y-chromosomal haplotypes using a new polymorphic A to G transition. Hum. Mol. Genet. 3, 2159–2161 (1994). · DOI
  3. Ruiz-Linares, A. et al. Geographic clustering of human Y-chromosome haplotypes. Ann. Hum. Genet. 60, 401– 408 (1996). · DOI
  4. Underhill, P.A., Jin, L., Zemans, R., Oefner, P.J. & Cavalli-Sforza, L.L. A pre-Columbian Y chromosome-specific transition and its implications for human evolutionary history. Proc. Natl Acad. Sci. USA 93, 196–200 (1996). · DOI
  5. Underhill, P.A. et al. Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Res. 7, 996–1005 (1997). · DOI
  6. Lewontin, R.C. The apportionment of human diversity. Evol. Biol. 6, 381–398 (1972).
  7. Barbujani, G., Magagni, A., Minch, E. & Cavalli-Sforza, L.L. An apportionment of human DNA diversity. Proc. Natl Acad. Sci. USA 94, 4516–4519 (1997). · DOI · Paper page
  8. Excoffier, L., Smouse, P.E. & Quattro, J.M. Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. Genetics 131, 479– 491 (1992). · DOI · Paper page
  9. Cavalli-Sforza, L.L. & Bodmer, W.F. The Genetics of Human Populations (Freeman, San Francisco, 1971).
  10. Miyata, T. et al. Molecular clock of silent substitution: at least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes. J. Mol. Evol. 19, 28– 35 (1982). · DOI
  11. Hammer, M.F. A recent common ancestry for human Y chromosomes. Nature 378, 376–378 (1995). · DOI
  12. Wijsman, E.M. & Cavalli-Sforza, L.L. Migration and genetic population structure with special reference to humans. Annu. Rev. Ecol. Syst. 15, 279–301 (1984). · DOI
  13. Slatkin, M. A measure of population subdivision based on microsatellite allele frequencies. Genetics 139, 457–462 (1995). · DOI
  14. Feldman, M.W., Kumm, J. & Pritchard, J.K. Mutation and migration in models of microsatellite evolution. in Microsatellites, Evolution and Applications (eds Goldstein, D.J. & Schloetterer, C.) (Oxford University Press, Oxford, in press).
  15. Thomas, J.M.C. Les Ngbaka de la Lobaye (Mouton, The Hague, 1963).
  16. White, D.R. Rethinking polygyny. Curr. Anthropol. 29, 529–572 (1988). · DOI · Paper page
  17. Dorjahn, V. R. in Continuity and Change in African Culture (eds Herskovits, M.J. & Bascomb, W.R.) 87–112 (University of Chicago Press, Chicago, 1959).
  18. Hrdlicka, A. Fecundity in Sioux women. Am. J. Phys. Anthropol. 16, 81–90 (1931). · DOI
  19. Isaac, B. Female fertility and marital form among the Mende of rural Upper Bambara Chiefdom, Sierra Leone. Ethnology 19, 297– 313 (1980). · DOI
  20. Hewlett, B., van de Koppel, J.M.H. & Cavalli-Sforza, L.L. Exploration ranges of Aka Pygmies of the Central African Republic. Man 17, 418–430 (1982). · DOI
  21. Ember, C.R. Myths about hunter-gatherers. Ethnology 17, 439–448 (1978). · DOI · Paper page
  22. Burton, M.L., Moore, C.C., Whiting, J.W.M. & Romney, A.K. Regions based on social structure. Curr. Anthropol. 37, 87–123 (1996). · DOI · Paper page
  23. Murdock, G. P. Ethnographic Atlas (University of Pittsburgh Press, Pittsburgh, 1967).
  24. Melnick, D.J. & Hoelzer, G.A. Differences in male and female macaque dispersal lead to contrasting distributions of nuclear and mitochondrial DNA variation. Int. J. Primatol. 13, 379–393 (1992). · DOI
  25. Keane, B., Dittus, W.P.J. & Melnick, D.J. Paternity assessment in wild groups of toque macaques Macaca sinica at Polonnaruwa, Sri Lanka using molecular markers. Mol. Ecol. 6, 267–282 (1997). · DOI
  26. Miller, S.A., Dykes, D.D. & Polesky, H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nuceic Acids Res. 16, 1215 (1988). · DOI
  27. Schneider, S., Kueffer, J. M., Roessli, D. & Excoffier, L. Arlequin ver. 1.1, University of Geneva (1997).
  28. Semino, O., Passarino, G., Brega, A., Fellous, M. & Santachiara-Benerecetti, A.S. A view of the Neolithic demic diffusion in Europe through two Y chromosome-specific markers. Am. J. Hum. Genet. 59, 964–968 (1996).
  29. Richards, M. et al. Paleolithic and Neolithic lineages in the European mitochondrial gene pool. Am. J. Hum. Genet. 59, 185– 203 (1996).
  30. Cavalli-Sforza, L.L., Menozzi, P. & Piazza, A. The History and Geography of Human Genes (Princeton University Press, Princeton, New Jersey, 1994).

Cited by

Metadata

Authors
Seielstad, M. T., Minch, E., & Cavalli-Sforza, L. L.
Venue
Nature Genetics
Publisher
Springer Science and Business Media LLC
Published
1998-11
Volume
20
Issue
3
Pages
278-280
ISSN
  • 1061-4036
  • 1546-1718
DOI
10.1038/3088
Cited by
450
References
0
Language
en
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review