Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

Doetschman, Thomas, Gregg, Ronald G., Maeda, Nobuyo, Hooper, Martin L., Melton, David W., Thompson, Simon, Smithies, Oliver·1987·Nature

DOI 10.1038/330576a0

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Disease-Specific Induced Pluripotent Stem Cells.
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“Strategies for inducing specific mutation or gene repair by homologous recombination were first established for the HPRT locus (Doetschman et al., 1987, 1988; Thomas and Capecchi, 1987).”
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Authors: Doetschman, T., Gregg, R. G., Maeda, N., Hooper, M. L., Melton, D. W., Thompson, S., & Smithies, O.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1987-12
Volume: 330
Issue: 6148
Pages: 576-578
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/330576a0
OpenAlex: W2032002636
Cited by: 786
References: 0
FWCI: 9.78
Type: journal article
Language: en
Open access: closed

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