The importance of repairing stalled replication forks

Cox, Michael M., Goodman, Myron F., Kreuzer, Kenneth N., Sherratt, David J., Sandler, Steven J., Marians, Kenneth J.·2000·Nature
DOI 10.1038/35003501

Cited by (999)

Items 501–600 of 999

  1. Crystal Structure of the Phage T4 Recombinase UvsX and Its Functional Interaction with the T4 SF2 Helicase UvsW
    Stefan Gajewski, Michael R. Webb, Vitold E. Galkin, Edward H. Egelman, Kenneth N. Kreuzer, Stephen W. White · 2010 · Journal of Molecular Biology
  2. Studying the organization of DNA repair by single-cell and single-molecule imaging
    Stephan Uphoff, Achillefs N. Kapanidis · 2014 · DNA repair
  3. The RecU Holliday junction resolvase acts at early stages of homologous recombination
    Cristina Cañas, Begoña Carrasco, Silvia Ayora, Juan C. Alonso · 2008 · Nucleic Acids Research
  4. Less Is More: Neisseria gonorrhoeae RecX Protein Stimulates Recombination by Inhibiting RecA
    Marielle C. Gruenig, Elizabeth A. Stohl, Sindhu Chitteni‐Pattu, H. Steven Seifert, Michael Matthew Cox · 2010 · Journal of Biological Chemistry
  5. Direct observation of end resection by RecBCD during double-stranded DNA break repair in vivo
    Jakub Wiktor, Marit van der Does, Lisa Büller, David J. Sherratt, Cees Dekker · 2017 · Nucleic Acids Research
  6. PARP inhibitor resistance in breast and gynecological cancer: Resistance mechanisms and combination therapy strategies
    Nannan Wang, Yang Yan, Dongdong Jin, Zhenan Zhang, Ke Shen, Jing Yang, Huanhuan Chen, Xinyue Zhao, Yang Li, Huaiwu Lu · 2022 · Frontiers in Pharmacology
  7. Elucidating a Key Intermediate in Homologous DNA Strand Exchange: Structural Characterization of the RecA–Triple-stranded DNA Complex Using Fluorescence Resonance Energy Transfer
    Jie Xiao, Scott F. Singleton · 2002 · Journal of Molecular Biology
  8. Replication-Fork Dynamics
    Karl E. Duderstadt, Rodrigo Reyes‐Lamothe, Antoine M. van Oijen, David J. Sherratt · 2013 · Cold Spring Harbor Perspectives in Biology
  9. Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination
    Richard T. Pomerantz, Isabel Kurth, Myron F. Goodman, Mike E. O’Donnell · 2013 · Nature Structural & Molecular Biology
  10. SSB and the RecG DNA helicase: an intimate association to rescue a stalled replication fork
    Piero R. Bianco, Yuri L. Lyubchenko · 2017 · Protein Science
  11. The RecRO pathway of DNA recombinational repair in Helicobacter pylori and its role in bacterial survival in the host
    Ge Wang, Leja F. Lo, Robert J. Maier · 2011 · DNA repair
  12. Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site
    Seijiro Shioi, Toyoyuki Ose, Katsumi Maenaka, Mitsunori Shiroishi, Yoshito Abe, Daisuke Kohda, Tsutomu Katayama, Tadashi Ueda · 2004 · Biochemical and Biophysical Research Communications
  13. Growth Phase Variation in Cell and Nucleoid Morphology in a Bacillus subtilis recA Mutant
    Stephen A. Sciochetti, Garry W. Blakely, Patrick J. Piggot · 2001 · Journal of Bacteriology
  14. Only Connect
    Susan L. Forsburg · 2002 · Molecular Cell
  15. Genomic Instability in Fungal Plant Pathogens
    Shay Covo · 2020 · Genes
  16. The PriA Replication Restart Protein Blocks Replicase Access Prior to Helicase Assembly and Directs Template Specificity through Its ATPase Activity
    Carol M. Manhart, Charles S. McHenry · 2012 · Journal of Biological Chemistry
  17. Characterization of two genes involved in chromate resistance in a Cr(VI)-hyper-resistant bacterium
    Francesca Decorosi, Enrico Tatti, Annalisa Mini, Luciana Giovannetti, Carlo Viti · 2009 · Extremophiles
  18. The Crystal Structure of the UvsW Helicase from Bacteriophage T4
    E. Allen Sickmier, Kenneth N. Kreuzer, Stephen W. White · 2004 · Structure
  19. RecBCD and RecJ/RecQ Initiate DNA Degradation on Distinct Substrates in UV-Irradiated Escherichia coli
    Kin-Hoe Chow, Justin Courcelle · 2007 · Radiation Research
  20. Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases
    Ja Yil Lee, Justin B. Steinfeld, Zhi Qi, Youngho Kwon, Patrick Sung, Eric C. Greene · 2017 · Journal of Biological Chemistry
  21. Effects of Tumor-associated Mutations on Rad54 Functions
    Marina Smirnova, Stephen Van Komen, Patrick Sung, Hannah L. Klein · 2004 · Journal of Biological Chemistry
  22. The RdgC protein of Escherichia coli binds DNA and counters a toxic effect of RecFOR in strains lacking the replication restart protein PriA
    Timothy Moore, Peter McGlynn, Hien-Ping Ngo, Gary J. Sharples, Robert G. Lloyd · 2003 · The EMBO Journal
  23. Critical role of R-loops in processing replication blocks
    Manel Camps · 2005 · Frontiers in bioscience
  24. End of the Beginning: Elongation and Termination Features of Alternative Modes of Chromosomal Replication Initiation in Bacteria
    Jayaraman Gowrishankar · 2015 · PLoS Genetics
  25. I came to a fork in the DNA and there was RecG
    Piero R. Bianco · 2015 · Progress in Biophysics and Molecular Biology
  26. Bacterial DNA repair genes and their eukaryotic homologues: 5. The role of recombination in DNA repair and genome stability.
    Anetta Nowosielska · 2007 · Acta Biochimica Polonica
  27. Rhodobacter sphaeroides LexA has dual activity: optimising and repressing recA gene transcription
    Angels Tapias · 2002 · Nucleic Acids Research
  28. Intein-mediated affinity-fusion purification of the Escherichia coli RecA protein
    Scott F. Singleton, Rebecca A. Simonette, Neil Christopher Sharma, Alberto I. Roca · 2002 · Protein Expression and Purification
  29. Biochemical attributes of mitotic and meiotic presynaptic complexes
    J. Brooks Crickard, Eric C. Greene · 2018 · DNA repair
  30. The genome of a hadal sea cucumber reveals novel adaptive strategies to deep-sea environments
    Guangming Shao, Tianliang He, Yinnan Mu, Pengfei Mu, Jingqun Ao, Xihuang Lin, Lingwei Ruan, YuGuang Wang, Yuan Gao, Dinggao Liu et al. · 2022 · iScience
  31. Homologous recombination: from model organisms to human disease.
    Mauro Modesti, Roland Kanaar · 2001 · Genome biology
  32. Inactivation of the DnaB Helicase Leads to the Collapse and Degradation of the Replication Fork: a Comparison to UV-Induced Arrest
    Jerilyn J. Belle, Andrew Casey, Charmain Tan Courcelle, Justin Courcelle · 2007 · Journal of Bacteriology
  33. Polymerase η and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation
    James E. Cleaver · 2002 · DNA repair
  34. Complementation of One RecA Protein Point Mutation by Another
    Julia M. Cox, Stephen N. Abbott, Sindhu Chitteni‐Pattu, Ross B. Inman, Michael M. Cox · 2006 · Journal of Biological Chemistry
  35. Roles of Rev1, Pol zeta, Pol32 and Pol eta in the bypass of chromosomal abasic sites in Saccharomyces cerevisiae.
    Paul A. Auerbach, B. Demple · 2010 · Mutagenesis
  36. Regulation of Deinococcus radiodurans RecA Protein Function via Modulation of Active and Inactive Nucleoprotein Filament States
    Khanh V. Ngo, Eileen T. Molzberger, Sindhu Chitteni‐Pattu, Michael Matthew Cox · 2013 · Journal of Biological Chemistry
  37. Cooperative Conformational Transitions Keep RecA Filament Active During ATPase Cycle
    Sung Hyun Kim, Kaushik Ragunathan, Jeehae Park, Chirlmin Joo, Doseok Kim, Taekjip Ha · 2014 · Journal of the American Chemical Society
  38. TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity
    Yuan Meng, Changwei Liu, Lei Shen, Mian Zhou, Wenpeng Liu, Claudia M. Kowolik, Judith L. Campbell, Li Zheng, Binghui Shen · 2019 · Nucleic Acids Research
  39. Transcriptional Activity of the Bacterial Replication Initiator DnaA
    Inoka P. Menikpurage, Kristin Woo, Paola E. Mera · 2021 · Frontiers in Microbiology
  40. Response of the Bacteriophage T4 Replisome to Noncoding Lesions and Regression of a Stalled Replication Fork
    Scott William Nelson, Stephen J. Benkovic · 2010 · Journal of Molecular Biology
  41. Specific amino acid residues in the β sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli
    Mark D. Sutton, Jill M. Duzen · 2005 · DNA repair
  42. Crystal structure and DNA ‐binding mode of K lebsiella pneumoniae primosomal P ri B protein
    Yen‐Hua Huang, Yu‐Hua Lo, Wenya Huang, Cheng‐Yang Huang · 2012 · Genes to Cells
  43. Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication
    Felipe Cortés‐Ledesma, Cristina Tous, Andrés Aguilera · 2007 · Nucleic Acids Research
  44. Human Mus81 and FANCB independently contribute to repair of DNA damage during replication
    Yuji Nomura, Noritaka Adachi, Hideki Koyama · 2007 · Genes to Cells
  45. Characterization of Staphylococcus aureus Primosomal DnaD Protein: Highly Conserved C-Terminal Region Is Crucial for ssDNA and PriA Helicase Binding but Not for DnaA Protein-Binding and Self-Tetramerization
    Yen‐Hua Huang, Yi Lien, Chien‐Chih Huang, Cheng-Yang Huang · 2016 · PLoS ONE
  46. Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level
    Mohamed A. Sobhy, Amer Bralić, Vlad‐Stefan Raducanu, Masateru Takahashi, Muhammad Tehseen, Fahad Rashid, Manal S. Zaher, Samir M. Hamdan · 2018 · Nucleic Acids Research
  47. Visualizing mutagenic repair: novel insights into bacterial translesion synthesis
    Asha Mary Joseph, Anjana Badrinarayanan · 2020 · FEMS Microbiology Reviews
  48. Stress-induced Condensation of Bacterial Genomes Results in Re-pairing of Sister Chromosomes
    Nelia Shechter, Liron Zaltzman, Allon Weiner, Vlad Brumfeld, Eyal Shimoni, Yael Fridmann‐Sirkis, Abraham Minsky · 2013 · Journal of Biological Chemistry
  49. A RecB-Like Helicase in Helicobacter pylori Is Important for DNA Repair and Host Colonization
    Ge Wang, Robert J. Maier · 2008 · Infection and Immunity
  50. The ATPase activity of E. coli RecA prevents accumulation of toxic complexes formed by erroneous binding to undamaged double stranded DNA
    Daniil V. Gataulin, Jeffrey N. Carey, Junya Li, Parisha P. Shah, Jennifer Grubb, Douglas K. Bishop · 2018 · Nucleic Acids Research
  51. Crystallographic and NMR Analyses of UvsW and UvsW.1 from Bacteriophage T4
    Iain D. Kerr, Sivashankar G. Sivakolundu, Zhenmei Li, Jeffrey Craig Buchsbaum, Luke A. Knox, Richard W. Kriwacki, Stephen W. White · 2007 · Journal of Biological Chemistry
  52. Running into problems: how cells cope with replicating damaged DNA
    Clare H. McGowan · 2003 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  53. Single-Molecule Analysis of Bacterial DNA Repair and Mutagenesis
    Stephan Uphoff, David J. Sherratt · 2017 · Annual Review of Biophysics
  54. The Bacterial RecA Protein: Structure, Function, and Regulation
    Michael M. Cox · 2006 · Springer eBooks
  55. Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasitePlasmodium falciparum:possible involvement in DNA replication and DNA damage response
    Pallabi Mitra, Khadija Banu, Abhijit S. Deshmukh, Naidu Subbarao, Suman Kumar Dhar · 2015 · Biochemical Journal
  56. Single Strand Annealing Plays a Major Role in RecA-Independent Recombination between Repeated Sequences in the Radioresistant Deinococcus radiodurans Bacterium
    Solenne Ithurbide, Esma Bentchikou, Geneviève Coste, Bruno Bost, Pascale Servant, Suzanne Sommer · 2015 · PLoS Genetics
  57. The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination
    Berina Eppink, Agnieszka A. Tafel, Katsuhiro Hanada, Ellen van Drunen, Ian David Hickson, Jeroen Essers, Roland Kanaar · 2011 · DNA repair
  58. Topoisomerase II– and Condensin-Dependent Breakage of MEC1ATR-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis
    Nadia Hashash, Anthony L. Johnson, S. Rita · 2012 · PLoS Genetics
  59. Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells
    Kang Wei Tan, Tuan Minh Pham, Asako Furukohri, Hisaji Maki, Masahiro Tatsumi Akiyama · 2015 · Nucleic Acids Research
  60. Dynamics of RecA-mediated repair of replication-dependent DNA breaks
    Vincent Amarh, Martin A. White, David R. F. Leach · 2018 · The Journal of Cell Biology
  61. Mechanisms of Maintaining Genetic Stability by Homologous Recombination
    Yoshizumi Ishino, Tatsuya Nishino, Kosuke Morikawa · 2005 · Chemical Reviews
  62. Mutational analyses of the human Rad51‐Tyr315 residue, a site for phosphorylation in leukaemia cells
    Yoshimasa Takizawa, Takashi Kinebuchi, Wataru Kagawa, Shigeyuki Yokoyama, Takehiko Shibata, Hitoshi Kurumizaka · 2004 · Genes to Cells
  63. Single-molecule insight into stalled replication fork rescue inEscherichia coli
    Piero R. Bianco, Yue Lu · 2021 · Nucleic Acids Research
  64. Isolation and Characterization of a Novel Human Radiosusceptibility Gene,NP951
    Masahiro Muto, Akira Fujimori, Mituru Nenoi, Kazuhiro Daino, Yoichi Matsuda, Asato Kuroiwa, Eiko Kubo, Yasuyoshi Kanari, Makoto Utsuno, Hideo Tsuji et al. · 2006 · Radiation Research
  65. A Rare Nucleotide Base Tautomer in the Structure of an Asymmetric DNA Junction
    Patricia A. Khuu, Pui Shing Ho · 2009 · Biochemistry
  66. Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair
    Hong Yan, Jill E. McCane, Thomas Toczylowski, Chin‐Yi Chen · 2005 · The Journal of Cell Biology
  67. The form of chromosomal DNA molecules in bacterial cells
    Arnold J. Bendich · 2001 · Biochimie
  68. Niacin status and treatment-related leukemogenesis
    James B. Kirkland · 2009 · Molecular Cancer Therapeutics
  69. Tn7
    Nancy Lynn Craig · 2007
  70. Topological locking restrains replication fork reversal
    Marta Fierro‐Fernández, Pablo Hernández, Dora B. Krimer, Andrzej Stasiak, Jorge B. Schvartzman · 2007 · Proceedings of the National Academy of Sciences
  71. D na T is a single‐stranded DNA binding protein
    Yen‐Hua Huang, Min‐Jon Lin, Cheng‐Yang Huang · 2013 · Genes to Cells
  72. Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination
    Xinguo Qian, Yujiong He, Xinfeng Ma, Michel N. Fodje, Paweł Grochulski, Yu Luo · 2006 · Journal of Biological Chemistry
  73. Structural Insight into the DNA-Binding Mode of the Primosomal Proteins PriA, PriB, and DnaT
    Yen‐Hua Huang, Cheng-Yang Huang · 2014 · BioMed Research International
  74. Helicase promotes replication re-initiation from an RNA transcript
    Bo Sun, Anupam Singh, Shemaila Sultana, James T. Inman, Smita S. Patel, Michelle Dong Wang · 2018 · Nature Communications
  75. Learning from the master: targets and functions of the CtrA response regulator in Brucella abortus and other alpha-proteobacteria
    Katy Poncin, Sébastien Gillet, Xavier De Bolle · 2018 · FEMS Microbiology Reviews
  76. Loss of heterozygosity and DNA damage repair in Saccharomyces cerevisiae
    Yasukazu Daigaku, Kingo Endo, Eri Watanabe, Tetsuya Ono, Kazuo Yamamoto · 2004 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  77. Replication Fork Reversal Occurs Spontaneously after Digestion but Is Constrained in Supercoiled Domains
    Marta Fierro‐Fernández, Pablo Hernández, Dora B. Krimer, Jorge B. Schvartzman · 2007 · Journal of Biological Chemistry
  78. Werner Syndrome Protein--Unwinding Function to Explain Disease
    Raymond J. Monnat, Yannick Saintigny · 2004 · Science of Aging Knowledge Environment
  79. Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres
    Mariana C. Gadaleta, Mukund M. Das, Hideki Tanizawa, Ya-Ting Chang, Ken-ichi Noma, Toru Nakamura, Eishi Noguchi · 2016 · PLoS Genetics
  80. The structural ensemble of a Holliday junction determined by X-ray scattering interference
    Thomas Zettl, Xuesong Shi, Steve L. Bonilla, Steffen M. Sedlak, Jan Lipfert, Daniel Herschlag · 2020 · Nucleic Acids Research
  81. Whole-genome sequencing and genomic-based acid tolerance mechanisms of Lactobacillus delbrueckii subsp. bulgaricus LJJ
    Weixun Li, Lan Yang, Wenlong Nan, Jing Lü, Shuwen Zhang, Obaroakpo Joy Ujiroghene, Xiaoyang Pang, Jiaping Lv · 2020 · Applied Microbiology and Biotechnology
  82. UvrD303, a Hyperhelicase Mutant That Antagonizes RecA-Dependent SOS Expression by a Mechanism That Depends on Its C Terminus
    Richard C. Centore, Michael C. Leeson, Steven J. Sandler · 2008 · Journal of Bacteriology
  83. Bacillus subtilis Bacteriophage SPP1-encoded Gene 34.1 Product is a Recombination-dependent DNA Replication Protein
    María I. Martínez-Jiménez, Juan C. Alonso, Silvia Ayora · 2005 · Journal of Molecular Biology
  84. Biochemical characterization of RecA variants that contribute to extreme resistance to ionizing radiation
    Joseph R. Piechura, Tzu-Ling Tseng, Hsin-Fang Hsu, Rose T Byrne, Tricia A. Windgassen, Sindhu Chitteni‐Pattu, John R. Battista, Hung‐Wen Li, Michael Matthew Cox · 2014 · DNA repair
  85. An ‘open’ structure of the RecOR complex supports ssDNA binding within the core of the complex
    Jens Radzimanowski, François Dehez, Adam R. Round, Axel Bidon‐Chanal, Sean M. McSweeney, Joanna Timmins · 2013 · Nucleic Acids Research
  86. Unwinding of Forked DNA Structures by UvrD
    Chris J. Cadman, Steven W. Matson, Peter McGlynn · 2006 · Journal of Molecular Biology
  87. Single-molecule imaging of Bacteroides fragilis AddAB reveals the highly processive translocation of a single motor helicase
    Marcel Reuter, Frances Parry, David T. F. Dryden, Garry W. Blakely · 2010 · Nucleic Acids Research
  88. Structure and Function of the PriC DNA Replication Restart Protein
    Sarah R. Wessel, Claudia C. Cornilescu, Gabriel Cornilescu, Alice Metz, Maxime Leroux, Kaifeng Hu, Steven J. Sandler, John L. Markley, James L. Keck · 2016 · Journal of Biological Chemistry
  89. Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells
    Andrea J. Hartlerode, Nicholas A. Willis, Anbazhagan Rajendran, John P. Manis, Ralph Scully · 2016 · PLoS Genetics
  90. Characterization of Newly Gained Introns in Daphnia Populations
    Wenli Li, Robert K. Kuzoff, Chen Khuan Wong, Abraham E. Tucker, Michael Lynch · 2014 · Genome Biology and Evolution
  91. Ribonuclease E Modulation of the Bacterial SOS Response
    Robert Manasherob, Christine Miller, Kwang-sun Kim, Stanley N. Cohen · 2012 · PLoS ONE
  92. Dynamics of the Interaction of RecG Protein with Stalled Replication Forks
    Zhiqiang Sun, Mohtadin Hashemi, Galina Warren, Piero R. Bianco, Yuri L. Lyubchenko · 2018 · Biochemistry
  93. RecA‐independent recombination: Dependence on the Escherichia coli RarA protein
    Kanika Jain, Elizabeth A. Wood, Zachary J Romero, Michael M. Cox · 2020 · Molecular Microbiology
  94. Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2
    Yuichi Morozumi, Ryohei Ino, S Ikawa, Naozumi Mimida, Takeshi Shimizu, Seiichi Toki, Hiroaki Ichikawa, Takehiko Shibata, Hitoshi Kurumizaka · 2013 · PLoS ONE
  95. Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination
    Tae‐Jin Kim, Sindhu Chitteni‐Pattu, Benjamin L. Cox, Elizabeth Anne Wood, Steven J. Sandler, Michael Matthew Cox · 2015 · PLoS Genetics
  96. In Vivo Evidence for a recA -Independent Recombination Process in Escherichia coli That Permits Completion of Replication of DNA Containing UV Damage in Both Strands
    Ali I. Ozgenc, Edward S. Szekeres, Christopher W. Lawrence · 2005 · Journal of Bacteriology
  97. A Postsynaptic Role for Rhp55/57 That Is Responsible for Cell Death in Δrqh1 Mutants Following Replication Arrest in Schizosaccharomyces pombe
    Justin C. Hope, Mohamed Maftahi, Greg A. Freyer · 2005 · Genetics
  98. Expression of thePemHomeobox Gene in Sertoli Cells Increases the Frequency of Adjacent Germ Cells with Deoxyribonucleic Acid Strand Breaks
    Chad M. Wayne, Keith A. Sutton, Miles Wilkinson · 2002 · Endocrinology
  99. Stimulation of Dmc1-mediated DNA strand exchange by the human Rad54B protein
    Naoyuki Sarai, Wataru Kagawa, Takashi Kinebuchi, Ako Kagawa, Kozo Tanaka, Kiyoshi Miyagawa, S Ikawa, Takehiko Shibata, Hitoshi Kurumizaka, Shigeyuki Yokoyama · 2006 · Nucleic Acids Research
  100. Frequent template switching in postreplication gaps: suppression of deleterious consequences by the Escherichia coli Uup and RadD proteins
    Zachary J Romero, Thomas J. Armstrong, Sarah S. Henrikus, Stefanie H. Chen, David J. Glass, Alexander E. Ferrazzoli, Elizabeth Anne Wood, Sindhu Chitteni‐Pattu, Antoine M. van Oijen, Susan T. Lovett et al. · 2019 · Nucleic Acids Research