The importance of repairing stalled replication forks

Mammalian Telomeres End in a Large Duplex Loop

Griffith, J. D., Comeau, L., Rosenfield, S., Stansel, R. M., Bianchi, A., Moss, H., & de Lange, T. (1999) · Cell · doi:10.1016/s0092-8674(00)80760-6 · Cited by 2,447 · see citing works

An alternative pathway for yeast telomere maintenance rescues est1− senescence

Lundblad, V., & Blackburn, E. H. (1993) · Cell · doi:10.1016/0092-8674(93)90234-h · Cited by 942 · see citing works

Recombinational Repair of DNA Damage in Escherichia coli and Bacteriophage λ

Kuzminov, A. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.4.751-813.1999 · Cited by 897 · see citing works

ISOLATION AND CHARACTERIZATION OF RECOMBINATION-DEFICIENT MUTANTS OF ESCHERICHIA COLI K12

Clark, A. J., & Margulies, A. D. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.2.451 · Cited by 828 · see citing works

MUTANTS OF ESCHERICHIA COLI K-12 DEFECTIVE IN DNA REPAIR AND IN GENETIC RECOMBINATION

Howard-Flanders, P., & Theriot, L. (1966) · Genetics · doi:10.1093/genetics/53.6.1137 · Cited by 636 · see citing works

RuvAB Acts at Arrested Replication Forks

Seigneur, M., Bidnenko, V., Ehrlich, S. D., & Michel, B. (1998) · Cell · doi:10.1016/s0092-8674(00)81772-9 · Cited by 538 · see citing works

UmuD′ 2 C is an error-prone DNA polymerase, Escherichia coli pol V

Tang, M., Shen, X., Frank, E. G., O’Donnell, M. E., Woodgate, R., & Goodman, M. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.8919 · Cited by 537 · see citing works

Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription

Kogoma, T. (1997) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.61.2.212-238.1997 · Cited by 525 · see citing works

The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis

Wagner, J. E., Grúz, P., Kim, S.-R., Yamada, M., Matsui, K., Fuchs, R. P., & Nohmi, T. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80376-7 · Cited by 474 · see citing works

DNA double‐strand breaks caused by replication arrest

Michel, B., Ehrlich, S. D., & Uzest, M. (1997) · The EMBO Journal · doi:10.1093/emboj/16.2.430 · Cited by 426 · see citing works

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication.

Malkova, A., Ivanov, E. L., & Haber, J. E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.14.7131 · Cited by 421 · see citing works

DNA recombination: the replication connection

Haber, J. E. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01413-9 · Cited by 412 · see citing works

RAD50 and RAD51 Define Two Pathways That Collaborate to Maintain Telomeres in the Absence of Telomerase

Le, S., Moore, J. K., Haber, J. E., & Greider, C. W. (1999) · Genetics · doi:10.1093/genetics/152.1.143 · Cited by 410 · see citing works

Collapse and repair of replication forks in Escherichia coli

Kuzminov, A. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.tb02403.x · Cited by 363 · see citing works

The Translocating RecBCD Enzyme Stimulates Recombination by Directing RecA Protein onto ssDNA in a χ-Regulated Manner

Anderson, D. G., & Kowalczykowski, S. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80315-3 · Cited by 324 · see citing works

PROKARYOTIC DNA REPLICATION

Marians, K. J. (1992) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.61.070192.003325 · Cited by 316 · see citing works

DNA synthesis dependent on genetic recombination: Characterization of a reaction catalyzed by purified bacteriophage T4 proteins

Formosa, T., & Alberts, B. (1986) · Cell · doi:10.1016/0092-8674(86)90522-2 · Cited by 248 · see citing works

Replication initiated at the origin (oriC) of the E. coli chromosome reconstituted with purified enzymes

Kaguni, J. M., & Kornberg, A. (1984) · Cell · doi:10.1016/0092-8674(84)90539-7 · Cited by 240 · see citing works

Chromosome Break-Induced DNA Replication Leads to Nonreciprocal Translocations and Telomere Capture

Bosco, G., & Haber, J. E. (1998) · Genetics · doi:10.1093/genetics/150.3.1037 · Cited by 220 · see citing works

recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli

Courcelle, J., Carswell-Crumpton, C., & Hanawalt, P. C. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.3714 · Cited by 218 · see citing works

Recombinational DNA Repair in Bacteria and the RecA Protein

Cox, M. M. (1999) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60726-6 · Cited by 217 · see citing works

“Break Copy” Duplication: A Model for Chromosome Fragment Formation in Saccharomyces cerevisiae

Morrow, D. M., Connelly, C. J., & Hieter, P. (1997) · Genetics · doi:10.1093/genetics/147.2.371 · Cited by 215 · see citing works

Role of PriA in Replication Fork Reactivation in Escherichia coli

Sandler, S. J., & Marians, K. J. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.1.9-13.2000 · Cited by 213 · see citing works

Mechanisms in Recombination

Grell, R. F. (1974) · Springer eBooks · doi:10.1007/978-1-4684-2133-0 · Cited by 203 · see citing works

Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex and RecA protein

Tang, M., Bruck, I., Eritja, R., Turner, J., Frank, E. G., Woodgate, R., O’Donnell, M. E., & Goodman, M. F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.17.9755 · Cited by 202 · see citing works

The DNA replication protein PriA and the recombination protein RecG bind D-loops

McGlynn, P., Al-Deib, A. A., Liu, J., Marians, K. J., & Lloyd, R. G. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1120 · Cited by 198 · see citing works

Homologous Genetic Recombination: The Pieces Begin to Fall into Place

Clark, A. J., & Sandler, S. J. (1994) · Critical Reviews in Microbiology · doi:10.3109/10408419409113552 · Cited by 197 · see citing works

RECOMBINATION AND RECOMBINATION-DEPENDENT DNA REPLICATION IN BACTERIOPHAGE T4

Mosig, G. (1998) · Annual Review of Genetics · doi:10.1146/annurev.genet.32.1.379 · Cited by 196 · see citing works

The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair

Kogoma, T., Cadwell, G. W., Barnard, K. G., & Asai, T. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.5.1258-1264.1996 · Cited by 180 · see citing works

Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage

Woodgate, R., & Ennis, D. G. (1991) · Molecular and General Genetics MGG · doi:10.1007/bf00264207 · Cited by 175 · see citing works

Differential Suppression of priA2::kan Phenotypes in Escherichia coli K-12 by Mutations in priA, lexA, and dnaC

Sandler, S. J., Samra, H. S., & Clark, A. J. (1996) · Genetics · doi:10.1093/genetics/143.1.5 · Cited by 173 · see citing works

The cytoplasmic domain of FtsK protein is required for resolution of chromosome dimers

Steiner, W. W., Liu, G., Donachie, W. D., & Kuempel, P. L. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01198.x · Cited by 167 · see citing works

A model for a umuDC -dependent prokaryotic DNA damage checkpoint

Opperman, T. J., Murli, S., Smith, B. T., & Walker, G. C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9218 · Cited by 166 · see citing works

Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response

Nurse, P., Zavitz, K. H., & Marians, K. J. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.21.6686-6693.1991 · Cited by 159 · see citing works

Chromosomal Rearrangements Occur in S. cerevisiae rfa1 Mutator Mutants Due to Mutagenic Lesions Processed by Double-Strand-Break Repair

Chen, C. C., Umezu, K., & Kolodner, R. D. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80109-4 · Cited by 157 · see citing works

A phenotype for enigmatic DNA polymerase II: A pivotal role for pol II in replication restart in UV-irradiated Escherichia coli

Rangarajan, S., Woodgate, R., & Goodman, M. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9224 · Cited by 153 · see citing works

Two alternative mechanisms for initiation of DNA replication forks in bacteriophage T4: priming by RNA polymerase and by recombination.

Luder, A., & Mosig, G. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.4.1101 · Cited by 148 · see citing works

Recombination by Replication

Kogoma, T. (1996) · Cell · doi:10.1016/s0092-8674(00)81229-5 · Cited by 133 · see citing works

A broadening view of recombinational DNA repair in bacteria

Cox, M. M. (1998) · Genes to Cells · doi:10.1046/j.1365-2443.1998.00175.x · Cited by 131 · see citing works

THE U.V. SENSITIVITY OF BACTERIA: ITS RELATION TO THE DNA REPLICATION CYCLE

Hanawalt, P. C. (1966) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1966.tb05756.x · Cited by 130 · see citing works

Replication fork assembly at recombination intermediates is required for bacterial growth

Liu, J., Xu, L., Sandler, S. J., & Marians, K. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3552 · Cited by 130 · see citing works

PriA-directed Assembly of a Primosome on D Loop DNA

Liu, J., & Marians, K. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25033 · Cited by 117 · see citing works

FtsK‐dependent and ‐independent pathways of Xer site‐specific recombination

Recchia, G. D., Aroyo, M., Wolf, D., Blakely, G., & Sherratt, D. J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.20.5724 · Cited by 113 · see citing works

Sister Chromatid Exchange Frequencies in Escherichia coli Analyzed by Recombination at the dif Resolvase Site

Steiner, W. W., & Kuempel, P. L. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.23.6269-6275.1998 · Cited by 107 · see citing works

Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand 1 1Edited by M. Yaniv

Cordeiro‐Stone, M., Makhov, A. M., Zaritskaya, L., & Griffith, J. D. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2847 · Cited by 102 · see citing works

Double-strand end repair via the RecBC pathway in Escherichia coli primes DNA replicationPreprint

Kuzminov, A., & Stahl, F. W. (1999) · Genes & Development · doi:10.1101/gad.13.3.345 · Cited by 101 · see citing works

dnaC mutations suppress defects in DNA replication‐ and recombination‐associated functions in priB and priC double mutants in Escherichia coli K‐12

Sandler, S. J., Marians, K. J., Zavitz, K. H., Coutu, J., Parent, M. A., & Clark, A. J. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01576.x · Cited by 95 · see citing works

Degradation of individual chromosomes in recA mutants of Escherichia coli

Skarstad, K., & Boye, E. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.17.5505-5509.1993 · Cited by 92 · see citing works

Cell division is required for resolution of dimer chromosomes at the dif locus of Escherichia coli

Steiner, W. W., & Kuempel, P. L. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00651.x · Cited by 90 · see citing works

Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNA

West, S. C., Cassuto, E., & Howard-Flanders, P. (1981) · Nature · doi:10.1038/294659a0 · Cited by 82 · see citing works

RecG helicase activity at three- and four-strand DNA structures

McGlynn, P., & Lloyd, R. G. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.15.3049 · Cited by 82 · see citing works

Instability of inhibited replication forks in E. coli

Kuzminov, A. (1995) · BioEssays · doi:10.1002/bies.950170810 · Cited by 81 · see citing works

A Replicator’s View of Recombination (and Repair)

Skalka, A. (1974) · Springer eBooks · doi:10.1007/978-1-4684-2133-0_37 · Cited by 77 · see citing works

Pathways for Homologous Recombination Between Chromosomal Direct Repeats in Salmonella typhimurium

Galitski, T., & Roth, J. R. (1997) · Genetics · doi:10.1093/genetics/146.3.751 · Cited by 69 · see citing works

PriA: At the Crossroads of DNA Replication and Recombination

Marians, K. J. (1999) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60719-9 · Cited by 66 · see citing works

SOS response as an adaptive response to DNA damage in prokaryotes

Shinagawa, H. (1996) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-9088-5_14 · Cited by 65 · see citing works

Tandem Repeat Recombination Induced by Replication Fork Defects in Escherichia coli Requires a Novel Factor, RadC

Saveson, C. J., & Lovett, S. T. (1999) · Genetics · doi:10.1093/genetics/152.1.5 · Cited by 64 · see citing works

Enzymology of DNA in Replication in Prokaryote

Marians, K. J., & McMacken, R. (1984) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238409113604 · Cited by 60 · see citing works

Dissecting the functional role of PriA protein‐catalysed primosome assembly in Escherichia coli DNA replication

Zavitz, K. H., & Marians, K. J. (1991) · Molecular Microbiology · doi:10.1111/j.1365-2958.1991.tb01846.x · Cited by 47 · see citing works

sbcB sbcC null mutations allow RecF‐mediated repair of arrested replication forks in rep recBC mutants

Bidnenko, V., Seigneur, M., Penel‐Colin, M., Bouton, M., Ehrlich, S. D., & Michel, B. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01532.x · Cited by 43 · see citing works

Recombinational crossroads: Eukaryotic enzymes and the limits of bacterial precedents

Cox, M. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.22.11764 · Cited by 32 · see citing works

Site‐specific recombination at dif by Haemophilus influenzae XerC

Neilson, L., Blakely, G., & Sherratt, D. J. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01231.x · Cited by 30 · see citing works

Enzyme Studies of ϕX174 DNA Replication

Arai, K., Arai, N., Shlomai, J., Kobori, J. A., Polder, L., Low, R. L., ̈bscher, U. H., Bertsch, L. L., & Kornberg, A. (1981) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60392-x · Cited by 17 · see citing works

Stochastic Gene Expression in a Single Cell

Elowitz, M. B., Levine, A. J., Siggia, E. D., & Swain, P. S. (2002) · Science · doi:10.1126/science.1070919 · Cited by 5,441 · see citing works

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073723 · Cited by 3,317 · see citing works

Cellular roles of DNA topoisomerases: a molecular perspective

Wang, J. C. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm831 · Cited by 2,364 · see citing works

How antibiotics kill bacteria: from targets to networks

Kohanski, M. A., Dwyer, D. J., & Collins, J. J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2333 · Cited by 2,266 · see citing works

Cell cycle checkpoint signaling through the ATM and ATR kinases

Abraham, R. T. (2001) · Genes & Development · doi:10.1101/gad.914401 · Cited by 1,966 · see citing works

ATR: an essential regulator of genome integrity

Cimprich, K. A., & Cortez, D. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2450 · Cited by 1,798 · see citing works

Cancer Susceptibility and the Functions of BRCA1 and BRCA2

Venkitaraman, A. R. (2002) · Cell · doi:10.1016/s0092-8674(02)00615-3 · Cited by 1,713 · see citing works

Surviving the Acid Test: Responses of Gram-Positive Bacteria to Low pH

Cotter, P. D., & Hill, C. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.3.429-453.2003 · Cited by 1,378 · see citing works

Chromosomal stability and the DNA double-stranded break connection

van Gent, D. C., Hoeijmakers, J. H. J., & Kanaar, R. (2001) · Nature Reviews Genetics · doi:10.1038/35056049 · Cited by 1,219 · see citing works

BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks

Moynahan, M. E., Pierce, A. J., & Jasin, M. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00174-5 · Cited by 1,007 · see citing works

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

Moynahan, M. E., & Jasin, M. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2851 · Cited by 923 · see citing works

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

Prakash, R., Zhang, Y., Feng, W., & Jasin, M. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016600 · Cited by 869 · see citing works

DNA Double-Strand Break Repair: All's Well that Ends Well

Wyman, C., & Kanaar, R. (2006) · Annual Review of Genetics · doi:10.1146/annurev.genet.40.110405.090451 · Cited by 806 · see citing works

Toward Maintaining the Genome: DNA Damage and Replication Checkpoints

Nyberg, K. A., Michelson, R. J., Putnam, C. W., & Weinert, T. A. (2002) · Annual Review of Genetics · doi:10.1146/annurev.genet.36.060402.113540 · Cited by 770 · see citing works

Oxidative Stress Resistance in<i>Deinococcus radiodurans</i>

Slade, D., & Radman, M. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00015-10 · Cited by 761 · see citing works

Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes

Goodman, M. F. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.083101.124707 · Cited by 727 · see citing works

RecQ helicases: caretakers of the genome

Hickson, I. D. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1012 · Cited by 680 · see citing works

DNA double-strand break repair: From mechanistic understanding to cancer treatment

HELLEDAY, T., LO, J., VANGENT, D., & ENGELWARD, B. (2007) · DNA Repair · doi:10.1016/j.dnarep.2007.02.006 · Cited by 640 · see citing works

Integrative and Conjugative Elements (ICEs): What They Do and How They Work

Johnson, C. M., & Grossman, A. D. (2015) · Annual Review of Genetics · doi:10.1146/annurev-genet-112414-055018 · Cited by 610 · see citing works

RecBCD Enzyme and the Repair of Double-Stranded DNA Breaks

Dillingham, M. S., & Kowalczykowski, S. C. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00020-08 · Cited by 586 · see citing works

Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance

Cirz, R. T., Chin, J. K., Andes, D. R., de Crécy‐Lagard, V., Craig, W. A., & Romesberg, F. E. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030176 · Cited by 576 · see citing works

SSB as an Organizer/Mobilizer of Genome Maintenance Complexes

Shereda, R. D., Kozlov, A. G., Lohman, T. M., Cox, M. M., & Keck, J. L. (2008) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230802341296 · Cited by 554 · see citing works

Is quorum sensing a side effect of diffusion sensing?

Redfield, R. R. (2002) · Trends in Microbiology · doi:10.1016/s0966-842x(02)02400-9 · Cited by 540 · see citing works

Recombination and the maintenance of plant organelle genome stability.

Maréchal, A., & Brisson, N. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03195.x · Cited by 501 · see citing works

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

Brown, E. J., & Baltimore, D. (2003) · Genes &amp; Development · doi:10.1101/gad.1067403 · Cited by 511 · see citing works

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cellsPreprint

Pierce, A. J., Hu, P., Han, M., Ellis, N. A., & Jasin, M. (2001) · Genes & Development · doi:10.1101/gad.946401 · Cited by 514 · see citing works

Replication fork stalling at natural impediments

Mirkin, E. V., & Mirkin, S. M. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00030-06 · Cited by 482 · see citing works

Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli

Dwyer, D. J., Kohanski, M. A., Hayete, B., & Collins, J. J. (2007) · Molecular Systems Biology · doi:10.1038/msb4100135 · Cited by 470 · see citing works

T-loops and the origin of telomeres

de Lange, T. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1359 · Cited by 461 · see citing works

Rad51 Recombinase and Recombination Mediators

Sung, P., Krejčí, L., Komen, S. V., & Sehorn, M. G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300027200 · Cited by 446 · see citing works

Defining the Roles of Nucleotide Excision Repair and Recombination in the Repair of DNA Interstrand Cross-Links in Mammalian Cells

Silva, I. U. D., McHugh, P. J., Clingen, P. H., & Hartley, J. A. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.21.7980-7990.2000 · Cited by 441 · see citing works

The Bacterial RecA Protein and the Recombinational DNA Repair of Stalled Replication Forks

Lusetti, S. L., & Cox, M. M. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.083101.133940 · Cited by 422 · see citing works

Structure, Molecular Mechanisms, and Evolutionary Relationships in DNA Topoisomerases

Corbett, K. D., & Berger, J. M. (2004) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.33.110502.140357 · Cited by 427 · see citing works

Regulation of Bacterial RecA Protein Function

Cox, M. M. (2007) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230701260258 · Cited by 412 · see citing works

The Saccharomyces cerevisiae Helicase Rrm3p Facilitates Replication Past Nonhistone Protein-DNA Complexes

Ivessa, A., Lenzmeier, B. A., Bessler, J. B., Goudsouzian, L. K., Schnakenberg, S. L., & Zakian, V. A. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00456-8 · Cited by 407 · see citing works

Recombinational repair and restart of damaged replication forks

McGlynn, P., & Lloyd, R. G. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm951 · Cited by 397 · see citing works

Identification and purification of two distinct complexes containing the five RAD51 paralogsPreprint

Masson, J., Tarsounas, M., Stasiak, A. Z., Stasiak, A., Punatar, R. S., McIlwraith, M. J., Benson, F. E., & West, S. C. (2001) · Genes & Development · doi:10.1101/gad.947001 · Cited by 395 · see citing works

Spatial and temporal organization of replicating Escherichia coli chromosomes

Lau, I. F., Filipe, S. R., Søballe, B., Økstad, O. A., Barre, F., & Sherratt, D. J. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03640.x · Cited by 391 · see citing works

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells11Edited by J. Karn

Arnaudeau, C., Lundin, C., & Helleday, T. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4564 · Cited by 387 · see citing works

Chemistry and Biology of DNA Repair

Schärer, O. D. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200523 · Cited by 381 · see citing works

Quinolones: Action and Resistance Updated

Drlica, K., Hiasa, H., Kerns, R. J., Malik, M., MUSTAEV, A. A., & Zhao, X. (2009) · Current Topics in Medicinal Chemistry · doi:10.2174/156802609789630947 · Cited by 377 · see citing works

Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance

McHugh, P. J., Spanswick, V. J., & Hartley, J. A. (2001) · The Lancet Oncology · doi:10.1016/s1470-2045(01)00454-5 · Cited by 378 · see citing works

Homologous repair of DNA damage and tumorigenesis:the BRCA connection

Jasin, M. (2002) · Oncogene · doi:10.1038/sj.onc.1206176 · Cited by 356 · see citing works

Structural dynamics of individual Holliday junctions

McKinney, S., Déclais, A., Lilley, D. M. J., & Ha, T. (2002) · Nature Structural Biology · doi:10.1038/nsb883 · Cited by 355 · see citing works

Characterization of homologous recombination induced by replication inhibition in mammalian cells

Saintigny, Y., Delacôte, F., Varès, G., Petitot, F., Lambert, S., Averbeck, D., & López, B. S. (2001) · The EMBO Journal · doi:10.1093/emboj/20.14.3861 · Cited by 334 · see citing works

Impact of Spontaneous Prophage Induction on the Fitness of Bacterial Populations and Host-Microbe Interactions

Nanda, A. M., Thormann, K. M., & Frunzke, J. (2014) · Journal of Bacteriology · doi:10.1128/jb.02230-14 · Cited by 319 · see citing works

The bacterial LexA transcriptional repressor

Butala, M., Žgur-Bertok, D., & Busby, S. J. W. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8378-6 · Cited by 315 · see citing works

Sperm DNA Fragmentation: A New Guideline for Clinicians

Agarwal, A. K., Majzoub, A. A., Baskaran, S., Selvam, M. K. P., Cho, C., Henkel, R., Finelli, R., Leisegang, K., Sengupta, P., Zenoaga-Barbăroşie, C., et al. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.200128 · Cited by 341 · see citing works

THE SOS RESPONSE: Recent Insights into umuDC -Dependent Mutagenesis and DNA Damage Tolerance

Sutton, M. D., Smith, B. T., Godoy, V. G., & Walker, G. C. (2000) · Annual Review of Genetics · doi:10.1146/annurev.genet.34.1.479 · Cited by 318 · see citing works

Effects of oxygen concentration and antioxidants on the in vitro developmental ability, production of reactive oxygen species (ROS), and DNA fragmentation in porcine embryos

Kitagawa, Y., Suzuki, K., Yoneda, A., & Watanabe, T. (2004) · Theriogenology · doi:10.1016/j.theriogenology.2004.01.011 · Cited by 307 · see citing works

Human DNA Polymerase η Promotes DNA Synthesis from Strand Invasion Intermediates of Homologous Recombination

McIlwraith, M. J., Vaisman, A., Liu, Y., Fanning, E., Woodgate, R., & West, S. C. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.10.001 · Cited by 304 · see citing works

Antigenic variation in trypanosomes: Enhanced phenotypic variation in a eukaryotic parasite

DAVIDBARRY, J., & McCulloch, R. (2001) · Advances in Parasitology/Advances in parasitology · doi:10.1016/s0065-308x(01)49037-3 · Cited by 305 · see citing works

Transcription as a source of genome instability

Kim, N., & Jinks-Robertson, S. (2012) · Nature reviews genetics · doi:10.1038/nrg3152 · Cited by 297 · see citing works

Real-Time Observation of RecA Filament Dynamics with Single Monomer Resolution

Joo, C., McKinney, S., Nakamura, M., Rasnik, I., Myong, S., & Ha, T. (2006) · Cell · doi:10.1016/j.cell.2006.06.042 · Cited by 298 · see citing works

Structural Analysis of DNA Replication Fork Reversal by RecG

Singleton, M. R., Scaife, S., & Wigley, D. B. (2001) · Cell · doi:10.1016/s0092-8674(01)00501-3 · Cited by 297 · see citing works

Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51

Wu, L., Davies, S. L., Levitt, N. C., & Hickson, I. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009471200 · Cited by 296 · see citing works

Impairment of replication fork progression mediates RNA polII transcription‐associated recombination

Prado, F., & Aguilera, A. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600602 · Cited by 294 · see citing works

Rescue of arrested replication forks by homologous recombination

Michel, B., Flores, M. J., Viguera, E., Grompone, G., Seigneur, M., & Bidnenko, V. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111008798 · Cited by 292 · see citing works

The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase

Karras, G. I., & Jentsch, S. (2010) · Cell · doi:10.1016/j.cell.2010.02.028 · Cited by 282 · see citing works

Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2

Venkitaraman, A. R. (2014) · Science · doi:10.1126/science.1252230 · Cited by 290 · see citing works

Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNAPreprint

Ivessa, A., Zhou, J., Schulz, V., Monson, E. K., & Zakian, V. A. (2002) · Genes & Development · doi:10.1101/gad.982902 · Cited by 284 · see citing works

Topological challenges to DNA replication: Conformations at the fork

Postow, L., Crisona, N. J., Peter, B. J., Hardy, C. D., & Cozzarelli, N. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111006998 · Cited by 280 · see citing works

Suffering in silence: the tolerance of DNA damage

Friedberg, E. C. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1781 · Cited by 271 · see citing works

Replisome assembly and the direct restart of stalled replication forks

Heller, R. C., & Marians, K. J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2058 · Cited by 268 · see citing works

Human Mus81-Associated Endonuclease Cleaves Holliday Junctions In Vitro

Chen, X., Melchionna, R., Aliouat‐Denis, C., Gaillard, P.-H. L., Blasina, A., de Weyer, I. V., Boddy, M. N., Russell, P. R., Vialard, J. E., & McGowan, C. H. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00375-6 · Cited by 267 · see citing works

Encoded errors: mutations and rearrangements mediated by misalignment at repetitive DNA sequences

Lovett, S. T. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04076.x · Cited by 267 · see citing works

Homologous Recombination Resolution Defect in Werner Syndrome

Saintigny, Y., Makienko, K., Swanson, C. L., Emond, M. J., & Monnat, R. J. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.20.6971-6978.2002 · Cited by 257 · see citing works

Tn7: smarter than we thought

Peters, J. E., & Craig, N. L. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35099006 · Cited by 256 · see citing works

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility proteinPreprint

Lomonosov, M., Anand, S., Sangrithi, M. N., Davies, R. C., & Venkitaraman, A. R. (2003) · Genes & Development · doi:10.1101/gad.279003 · Cited by 256 · see citing works

Motoring along with the bacterial RecA protein

Cox, M. M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2099 · Cited by 252 · see citing works

Natural Competence and the Evolution of DNA Uptake Specificity

Mell, J. C., & Redfield, R. J. (2014) · Journal of Bacteriology · doi:10.1128/jb.01293-13 · Cited by 251 · see citing works

Double-strand breaks and tumorigenesis

Pierce, A. J., Stark, J. M., Araujo, F. D., Moynahan, M. E., Berwick, M., & Jasin, M. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02149-3 · Cited by 269 · see citing works

DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae

Broomfield, S., Hryciw, T., & Xiao, W. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(01)00091-x · Cited by 243 · see citing works

Mre11 Protein Complex Prevents Double-Strand Break Accumulation during Chromosomal DNA Replication

Costanzo, V., Robertson, K., Bibikova, M., Kim, E., Grieco, D., Gottesman, M., Carroll, D., & Gautier, J. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00294-5 · Cited by 239 · see citing works

DNA Damage Responses in Prokaryotes: Regulating Gene Expression, Modulating Growth Patterns, and Manipulating Replication ForksPreprint

Kreuzer, K. N. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012674 · Cited by 228 · see citing works

Preventing replication fork collapse to maintain genome integrity

Cortez, D. (2015) · DNA Repair · doi:10.1016/j.dnarep.2015.04.026 · Cited by 223 · see citing works

Positive Torsional Strain Causes the Formation of a Four-way Junction at Replication Forks

Postow, L., Ullsperger, C., Keller, R. W., Bustamante, C., Vologodskii, A. V., & Cozzarelli, N. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006736200 · Cited by 237 · see citing works

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

Griffin, C. S., Simpson, P. J., Wilson, C. R., & Thacker, J. (2000) · Nature Cell Biology · doi:10.1038/35036399 · Cited by 232 · see citing works

Do bacteria have sex?

Redfield, R. J. (2001) · Nature Reviews Genetics · doi:10.1038/35084593 · Cited by 230 · see citing works

Recombinational DNA Repair of Damaged Replication Forks inEscherichia coli: Questions

Cox, M. M. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.090016 · Cited by 226 · see citing works

The many faces of DNA polymerases: Strategies for mutagenesis and for mutational avoidance

Friedberg, E. C., Feaver, W. J., & Gerlach, V. L. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.120152397 · Cited by 222 · see citing works

Replication fork reversal and the maintenance of genome stability

Atkinson, J., & McGlynn, P. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp244 · Cited by 221 · see citing works

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage

Vance, J. R., & Wilson, T. E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202242599 · Cited by 217 · see citing works

The Bacterial RecA Protein as a Motor Protein

Cox, M. M. (2003) · Annual Review of Microbiology · doi:10.1146/annurev.micro.57.030502.090953 · Cited by 213 · see citing works

Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

Maser, R. S., Mirzoeva, O. K., Wells, J. M., Olivares, H. A., Williams, B. R., Zinkel, R. A., Farnham, P., & Petrini, J. H. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.6006-6016.2001 · Cited by 212 · see citing works

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways

Hussain, S. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh135 · Cited by 207 · see citing works

Spontaneous DNA breakage in single living Escherichia coli cells

Pennington, J. M., & Rosenberg, S. M. (2007) · Nature Genetics · doi:10.1038/ng2051 · Cited by 206 · see citing works

Linking the Cellular Functions ofBRCAGenes to Cancer Pathogenesis and Treatment

Venkitaraman, A. R. (2008) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathol.3.121806.151422 · Cited by 199 · see citing works

SOS-induced DNA polymerases enhance long-term survival and evolutionary fitness

Yeiser, B., Pepper, E. D., Goodman, M. F., & Finkel, S. E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092269199 · Cited by 202 · see citing works

An expanded view of bacterial DNA replication

Noirot‐Gros, M., Dervyn, E., Wu, L. J., Mervelet, P., Errington, J., Ehrlich, S. D., & Noirot, P. H. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122040799 · Cited by 200 · see citing works

Mechanisms of apoptosis induction by nucleoside analogs

Sampath, D., Rao, V. A., & Plunkett, W. K. (2003) · Oncogene · doi:10.1038/sj.onc.1207229 · Cited by 200 · see citing works

Tracing the network connecting brca and fanconi anaemia proteins

Venkitaraman, A. R. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1321 · Cited by 196 · see citing works

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair

Kais, Z., Rondinelli, B., Holmes, A. L., O’Leary, C., Kozono, D., D’Andrea, A. D., & Ceccaldi, R. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.031 · Cited by 198 · see citing works

Bacterial Chromosome Dynamics

Sherratt, D. J. (2003) · Science · doi:10.1126/science.1084780 · Cited by 199 · see citing works

Bacteriophage replication modules

Weigel, C., & Seitz, H. (2006) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2006.00015.x · Cited by 196 · see citing works

Enzymology of the repair of free radicals-induced DNA damage

Gros, L., Saparbaev, M. K., & Laval, J. (2002) · Oncogene · doi:10.1038/sj.onc.1206005 · Cited by 196 · see citing works

RecE/RecT and Redα/Redβ initiate double-stranded break repair by specifically interacting with their respective partnersPreprint

Muyrers, J. P. P., Zhang, Y., Buchholz, F., & Stewart, A. F. (2000) · Genes & Development · doi:10.1101/gad.14.15.1971 · Cited by 194 · see citing works

The replisome uses mRNA as a primer after colliding with RNA polymerase

Pomerantz, R. T., & O’Donnell, M. E. (2008) · Nature · doi:10.1038/nature07527 · Cited by 190 · see citing works

Managing DNA polymerases: Coordinating DNA replication, DNA repair, and DNA recombination

Sutton, M. D., & Walker, G. C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111036998 · Cited by 184 · see citing works

Base triplet stepping by the Rad51/RecA family of recombinases

Lee, J. Y., Terakawa, T., Qi, Z., Steinfeld, J. B., Redding, S., Kwon, Y., Gaines, W. A., Zhao, W., Sung, P., & Greene, E. C. (2015) · Science · doi:10.1126/science.aab2666 · Cited by 182 · see citing works

Recombinational DNA Repair of Damaged Replication Forks inEscherichia coli: Questions

Cox, M. M. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.090016 · Cited by 226 · see citing works

Review The nonmutagenic repair of broken replication forks via recombination

Cox, M. M. (2002)

The nonmutagenic repair of broken replication forks via recombination

Cox, M. M. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(02)00256-7 · Cited by 112 · see citing works

Recombinational DNA Repair in Bacteria and the RecA Protein

Cox, M. M. (1999) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60726-6 · Cited by 217 · see citing works

Recombinational DNA Repair in Bacteria: Postreplication

Rice, K. P., & Cox, M. M. (2001) · Encyclopedia of Life Sciences · doi:10.1038/npg.els.0000689 · Cited by 7 · see citing works