Searching for genetic determinants in the new millennium

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Botstein, D., White, R. L., Skolnick, M. H., & Davis, R. W. (1980) · Europe PMC (PubMed Central) · Cited by 8,327

The Future of Genetic Studies of Complex Human Diseases

Risch, N., & Merikangas, K. (1996) · Science · doi:10.1126/science.273.5281.1516 · Cited by 5,355

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

Lander, E. S., & Kruglyak, L. (1995) · Nature Genetics · doi:10.1038/ng1195-241 · Cited by 5,236

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Spielman, R. S., McGinnis, R. E., & Ewens, W. J. (1993) · PubMed · Cited by 3,679

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Ellis, M. C., Fullan, A., et al. (1996) · Nature Genetics · doi:10.1038/ng0896-399 · Cited by 3,664

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

Weber, J. L., & May, P. E. (1989) · Europe PMC (PubMed Central) · Cited by 3,399

Genomic Control for Association Studies

Devlin, B., & Roeder, K. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.00997.x · Cited by 3,162 · cited 1×

A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.

Litt, M., & Luty, J. A. (1989) · PubMed · Cited by 1,962

Sequential tests for the detection of linkage.

Morton, N. E. (1955) · PubMed · Cited by 1,590

An introduction to genetic statistics

Kempthorne, O. (1957) · Medical Entomology and Zoology · Cited by 1,552

Tell-Tale SNPs: The Role of CYP2B6 in Methadone Fatalities

Ahmad, T. Z., Sabet, S., Primerano, D. A., Richards‐Waugh, L. L., & Rankin, G. O. (2016) · Journal of Analytical Toxicology · doi:10.1093/jat/bkw135 · Cited by 38

The Genetic Analysis of Multiple sclerosis in EuropeanS: concepts and design

Sawcer, S. J., & Compston, A. (2003) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2003.08.035 · Cited by 38

A scan statistic for identifying chromosomal patterns of SNP association

Sun, Y. V., Levin, A. M., Boerwinkle, E., Robertson, H., & Kardia, S. L. R. (2006) · Genetic Epidemiology · doi:10.1002/gepi.20173 · Cited by 38

PHARMACOGENOMICS OF ACUTE LEUKEMIA

Cheok, M. H.-C., Lugthart, S., & Evans, W. E. (2006) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.100018 · Cited by 38

Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene

Cox, N. J. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.20.2301 · Cited by 38

Detection of Oncogenic Mutations in the EGFR Gene in Lung Adenocarcinoma with Differential Sensitivity to EGFR Tyrosine Kinase InhibitorsPreprint

Thomas, R. K., Greulich, H. E., Yuza, Y., LEE, J. C., Tengs, T., Feng, W. W., CHEN, T.-H., Nickerson, E., SIMONS, J., EGHOLM, M., et al. (2005) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2005.70.056 · Cited by 38

MALDI Mass Spectrometry for Nucleic Acid Analysis

Gao, X., Tan, B. H., Sugrue, R. J., & Tang, K. (2012) · Topics in current chemistry · doi:10.1007/128_2012_366 · Cited by 37

Leveraging Hierarchical Population Structure in Discrete Association Studies

Carlson, J. M., Kadie, C. M., Mallal, S. A., & Heckerman, D. E. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000591 · Cited by 37

Genome‐wide Association Study of Agronomic Traits in a Spring‐Planted North American Elite Hard Red Spring Wheat Panel

Godoy, J., Gizaw, S. A., Chao, S., Blake, N. K., Carter, A. H., Cuthbert, R. D., Dubcovsky, J., Hucl, P., Kephart, K. D., Pozniak, C. J., et al. (2018) · Crop Science · doi:10.2135/cropsci2017.07.0423 · Cited by 37

Mannose-binding lectin haplotypes influence Brucella abortus infection in the water buffalo (Bubalus bubalis)

Capparelli, R., Parlato, M., Amoroso, M. G., Roperto, S., Marabelli, R., Roperto, F. P., & Iannelli, D. (2008) · Immunogenetics · doi:10.1007/s00251-008-0284-4 · Cited by 36

Genome-wide SNP association: Identification of susceptibility alleles for osteoarthritis

Abel, K. J., Reneland, R., Kammerer, S., Mah, S. P., Hoyal, C. R., Cantor, C. R., Nelson, M. R., & Braun, A. D. (2005) · Autoimmunity Reviews · doi:10.1016/j.autrev.2005.07.005 · Cited by 35

Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis: Table 1

Capon, F., Helms, C., Veal, C., Tillman, D., Burden, A. D., Barker, J. N., Bowcock, A. M., & Trembath, R. C. (2004) · Journal of Medical Genetics · doi:10.1136/jmg.2004.018226 · Cited by 37

Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease

Bodner, S. M., Berrettini, W. H., Deerlin, V. M. V., Bennett, D. A., Wilson, R. S., Trojanowski, J. Q., & Arnold, S. E. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30154 · Cited by 37

Genetic architecture of hemoglobin F control

Menzel, S., & Thein, S. L. (2009) · Current Opinion in Hematology · doi:10.1097/moh.0b013e328329d07a · Cited by 37

A genome screen for linkage disequilibrium in HLA-DRB1*15-positive Germans with multiple sclerosis based on 4666 microsatellite markers

Goedde, R., Sawcer, S. J., Böehringer, S., Miterski, B., Sindern, E., Haupts, M. R., Schimrigk, S., Compston, A., & Epplen, J. T. (2002) · Human Genetics · doi:10.1007/s00439-002-0801-8 · Cited by 37

Single nucleotide polymorphisms and disease gene mapping.

Bell, J. I. (2002) · Arthritis Research · doi:10.1186/ar555 · Cited by 39

Modifier genes in Mendelian disorders: the example of hemoglobin disorders

Sankaran, V. G., Lettre, G., Orkin, S. H., & Hirschhorn, J. N. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05821.x · Cited by 37

Genetic risks and childhood-onset asthma

Cookson, W., Moffatt, M. F., & Strachan, D. P. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.06.026 · Cited by 37

Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease

Baessler, A., Fischer, M., Mayer, B., Koehler, M., Wiedmann, S., Stark, K. J., Doering, A., Erdmann, J., Riegger, G. A. J., Schunkert, H., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm033 · Cited by 36

Multi-omics in mesial temporal lobe epilepsy with hippocampal sclerosis: Clues into the underlying mechanisms leading to disease

Bruxel, E. M., Bruno, D. D. C. F., do Canto, A. M., Geraldis, J. C., Godoi, A. B., Martin, M., & Lopes‐Cendes, Í. (2021) · Seizure · doi:10.1016/j.seizure.2021.03.002 · Cited by 36

Association of Agronomic Traits with SNP Markers in Durum Wheat (Triticum turgidum L. durum (Desf.))

Hu, X., Ren, J., Ren, X., Huang, S., Sabiel, S. A. I., Luo, M., Nevo, E., Fu, C., Peng, J. H., & Sun, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0130854 · Cited by 37

Association Study of 69 Genes in the Ret Pathway Identifies Low-penetrance Loci in Sporadic Medullary Thyroid Carcinoma

Ruiz‐Llorente, S., Montero‐Conde, C., Milne, R. L., Moya, C. M., Cebrián, A., Letón, R., Cascón, A., Mercadillo, F., Landa, I., Borrego, S., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-1638 · Cited by 36

Recent progress in livestock genomics and potential impact on breeding programs

Georges, M. (2001) · Theriogenology · doi:10.1016/s0093-691x(00)00442-8 · Cited by 36

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N., & Fukumaki, Y. (2001) · Psychiatric Genetics · doi:10.1097/00041444-200109000-00005 · Cited by 37

The Linking of Sociology and Biology

Guo, G. (2006) · Social Forces · doi:10.1353/sof.2006.0126 · Cited by 36

Association between lymphotoxin-α (tumor necrosis factor-β) intron polymorphism and predisposition to severe sepsis is modified by gender and age

Watanabe, E., Buchman, T. G., Hirasawa, H., & Zehnbauer, B. A. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181bc805d · Cited by 35

TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C

Askar, E., Bregadze, R., Mertens, J., Schweyer, S., Rosenberger, A., Ramadori, G. P., & Mihm, S. (2009) · Journal of Medical Virology · doi:10.1002/jmv.21491 · Cited by 35

Platelet glycoprotein Ibα and integrin α2β1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel

Paola, J. D., Jugessur, A., GOLDMAN, T., Reiland, J., TALLMAN, D., SAYAGO, C., & Murray, J. C. (2005) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2005.01273.x · Cited by 35

Genetics of schizophrenia: from animal models to clinical studies.

Joober, R., Boksa, P., Benkelfat, C., & Rouleau, G. (2002) · Journal of Psychiatry & Neuroscience · doi:10.1139/jpn.0252 · Cited by 30

Long-Term Consequences of Hematopoietic Stem Cell Transplantation: Current State of the Science

Baker, K. S., Armenian, S. H., & Bhatia, R. (2009) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2009.09.017 · Cited by 35

An Integrative Approach for Studying the Etiology of Alcoholism and

Jacob, T., Sher, K. J., Bucholz, K. K., True, W., Sirevaag, E. J., Rohrbaugh, J., Nelson, E. C., Neuman, R. J., Todd, R. D., Slutske, W. S., et al. (2001) · Twin Research · doi:10.1375/twin.4.2.103 · Cited by 39

Two HLA DRB 1 alleles confer independent genetic susceptibility to Graves disease: Relevance of cross-population studies

Marga, M., Denisova, A., Sochnev, A., Pīrāgs, V., & Farid, N. R. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.1431 · Cited by 35

Sex hormone-binding globulin polymorphisms in familial and sporadic breast cancer

Försti, A., Jin, Q., Grzybowska, E. A., Söderberg, M. P., Zientek, H., Sieminska, M., Rogozińska-Szczepka, J., Chmielik, E., Utracka-Hutka, B., & Hemminki, K. (2002) · Carcinogenesis · doi:10.1093/carcin/23.8.1315 · Cited by 35

Mendelian Randomization Studies Promise to Shorten the Journey to FDA Approval

Roberts, R. (2018) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2018.08.001 · Cited by 31

ADHD: strategies to unravel its genetic architecture

Buitelaar, J. K. (2006) · Springer eBooks · doi:10.1007/3-211-31222-6_1 · Cited by 34

Population-specific functional variant of the TPH2 gene 2755C>A polymorphism contributes risk association to major depression and anxiety in Chinese peripartum women

Lin, Y.-M. J., Ko, H., Chang, F., Yeh, T. L., & Sun, H. S. (2009) · Archives of Women s Mental Health · doi:10.1007/s00737-009-0088-z · Cited by 36

The role of linkage studies for common diseases

Gulcher, J. R. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00188-x · Cited by 34

Linkage Disequilibrium Grouping of Single Nucleotide Polymorphisms (SNPs) Reflecting Haplotype Phylogeny for Efficient Selection of Tag SNPs

Takeuchi, F., Yanai, K., Morii, T., Ishinaga, Y., Taniguchi-Yanai, K., Nagano, S., & Kato, N. (2005) · Genetics · doi:10.1534/genetics.104.038232 · Cited by 37

Immunogenetics of pemphigus: An update

Tron, F., Gilbert, D., Joly, P., Mouquet, H., Drouot, L., Ayed, M. B., Sellami, M., Masmoudi, H., & Makni, S. (2006) · Autoimmunity · doi:10.1080/08916930600971497 · Cited by 32

Combined Linkage and Association Tests in Mx

Posthuma, D., de Geus, E. D., Boomsma, D., & Neale, M. (2004) · Behavior Genetics · doi:10.1023/b:bege.0000013732.19486.74 · Cited by 32

Genetic Variation: Polymorphisms and Mutations

Wright, A. F. (2005) · Encyclopedia of Life Sciences · doi:10.1038/npg.els.0005005 · Cited by 34

Premature ovarian failure and gene polymorphisms

van Dooren, M. F., Bertoli‐Avella, A. M., & Oldenburg, R. A. (2009) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e32832e0813 · Cited by 34

Electroanalysis of single-nucleotide polymorphism by hairpin DNA architectures

Abi, A., & Ferapontova, E. E. (2012) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-012-6633-z · Cited by 33

Genetic association studies in female reproduction: from candidate-gene approaches to genome-wide mapping

Zhao, H., & Chen, Z. (2013) · Molecular Human Reproduction · doi:10.1093/molehr/gat040 · Cited by 33

Correlation and Path Coefficient Analyses in Sugarcane Genotypes of Ethiopia

Tena, E., Mekbib, F., & Ayana, A. (2016) · American Journal of Plant Sciences · doi:10.4236/ajps.2016.710141 · Cited by 33

Genome-wide association mapping of spot blotch resistance to three different pathotypes of Cochliobolus sativus in the USDA barley core collection

Wang, R., Leng, Y., Ali, S., Wang, M., & Zhong, S. (2017) · Molecular Breeding · doi:10.1007/s11032-017-0626-8 · Cited by 33

Epistasis: Searching for Interacting Genetic Variants Using Crosses

Ehrenreich, I. M. (2017) · Genetics · doi:10.1534/genetics.117.203059 · Cited by 35

Understanding the molecular basis of celiac disease: What genetic studies reveal

Monsuur, A. J., & Wijmenga, C. (2006) · Annals of Medicine · doi:10.1080/07853890600989054 · Cited by 33

Genomic Epidemiology of Complex Disease: The Need for an Electronic Evidence-based Approach to Research Synthesis

Bracken, M. B. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi200 · Cited by 33

Multistage Sampling for Genetic Studies

Elston, R. C., Lin, D., & Gang, Z. (2007) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.8.080706.092357 · Cited by 33

Genetic Variation and Human Aging: Progress and Prospects

Melzer, D. R., Hurst, A. J., & Frayling, T. M. (2007) · The Journals of Gerontology Series A · doi:10.1093/gerona/62.3.301 · Cited by 35

Candidate gene case-control studies

Daly, A. K. (2003) · Pharmacogenomics · doi:10.1517/phgs.4.2.127.22629 · Cited by 31

Genetic Analyses in Asthma

Hakonarson, H. H., & Halapi, E. C. (2002) · American Journal of PharmacoGenomics · doi:10.2165/00129785-200202030-00001 · Cited by 33

Calpain 10: the first positional cloning of a gene for type 2 diabetes?

Permutt, M. A., Bernal‐Mizrachi, E., & Inoue, H. (2000) · Journal of Clinical Investigation · doi:10.1172/jci11228 · Cited by 33

Cardiovascular Pharmacogenomics: Current Status, Future Prospects

Anderson, J. L., Carlquist, J. F., Home, B. D., & Muhlestein, J. B. (2003) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/107424840300800i110 · Cited by 33

Manhattan versus Reykjavik

Abbott, A. (2000) · Nature · doi:10.1038/35019167 · Cited by 32

An overview of the genetic susceptibility to alcoholism

Buscemi, L., & Turchi, C. (2011) · Medicine Science and the Law · doi:10.1258/msl.2010.010054 · Cited by 34

Genetic aspects of pulmonary responses to inhaled pollutants

Kleeberger, S. R. (2005) · Experimental and Toxicologic Pathology · doi:10.1016/j.etp.2005.05.017 · Cited by 32

The Search for Genetic Variants and Epigenetics Related to Asthma

Lee, S., Park, J., & Park, C. (2011) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2011.3.4.236 · Cited by 33

Identification of QTLs for drought tolerance traits on wheat chromosome 2A using association mapping.

Ahmad, M., Khan, S. H., Khan, A. S., Kazi, A. M., & Basra, S. M. A. (2014) · International Journal of Agriculture and Biology · Cited by 32

Calcium-sensing receptor gene polymorphisms in patients with calcium nephrolithiasis

Vezzoli, G., Terranegra, A., & Soldati, L. (2012) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0b013e3283542290 · Cited by 32

The Genetics of Epilepsy in the Belgian Tervuren and Sheepdog

Oberbauer, A. M. (2003) · Journal of Heredity · doi:10.1093/jhered/esg010 · Cited by 32

Discovery and development of integrative biological markers for schizophrenia

Oertel‐Knöchel, V., Bittner, R. A., Knöchel, C., Prvulovic, D., & Hampel, H. J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.05.006 · Cited by 33

Definition of candidate low risk APC alleles in a Swedish population

Zhou, X., Eriksson, U. K., Werelius, B., Kressner, U., Xiao, S., & Lindblom, A. (2004) · International Journal of Cancer · doi:10.1002/ijc.20173 · Cited by 32

Cancer classification and pathway discovery using non-negative matrix factorization

Zeng, Z., Vo, A. H., Mao, C., Clare, S. E., Khan, S. A., & Luo, Y. (2019) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2019.103247 · Cited by 35

Backward Haplotype Transmission Association (BHTA) Algorithm – A Fast Multiple-Marker Screening Method

Lo, S., & Zheng, T. (2002) · Human Heredity · doi:10.1159/000066194 · Cited by 31

Chromosome 21: from sequence to applications

Antonarakis, S. E. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00185-4 · Cited by 33

No association between non‐violent suicidal behavior and the serotonin transporter promoter polymorphism

Courtet, P., Burési, C., Abbar, M., Baud, P., Boulenger, J., Castelnau, D., Mouthon, D., & Malafosse, A. (2002) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10756 · Cited by 32

Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy

Chioza, B. A., Osei‐Lah, A. D., Nashef, L. A. M., Suárez-Merino, B., Wilkie, H., Sham, P. C., Knight, J., Asherson, P. J., & MAKOFF, A. J. (2002) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200896 · Cited by 32

Sequence variation and disease in the wake of the draft human genome

Goodstadt, L. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.20.2209 · Cited by 32

Identification of genetic variants in the neuronal form of tryptophan hydroxylase (TPH2)

Breidenthal, S. E., White, D. J., & Glatt, C. E. (2004) · Psychiatric Genetics · doi:10.1097/01.ypg.0000107929.32051.58 · Cited by 32

One gene and one outcome? No way

Chanock, S. J., & Wacholder, S. (2002) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(02)02356-0 · Cited by 32

Polygenic Inherited Predisposition to Breast CancerPreprint

Ponder, B. A. J., Antoniou, A. C., Dunning, A. M., Easton, D. F., & Pharoah, P. D. P. (2005) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2005.70.029 · Cited by 31

Linking Genes to Cardiovascular Diseases: Gene Action and Gene–Environment Interactions

Pasipoularides, A. D. (2015) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-015-9658-9 · Cited by 32

Genome‐wide and digital polymerase chain reaction epigenetic assessments of alcohol consumption

Philibert, R. A., Dogan, M. V., Noel, A., Miller, S., Krukow, B., Papworth, E., Cowley, J., Knudsen, A., Beach, S. R. H., & Black, D. W. (2018) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32636 · Cited by 30

Reduction of Sample Heterogeneity through Use of Population Substructure: An Example from a Population of African American Families with Sarcoidosis

Thompson, C. L., Rybicki, B. A., Iannuzzi, M. C., Elston, R. C., Iyengar, S. K., & Gray‐McGuire, C. (2006) · The American Journal of Human Genetics · doi:10.1086/507847 · Cited by 31

Candidate gene polymorphisms in solid cancers

Balasubramanian, S. P., Cox, A., Brown, N. J., & Reed, M. (2004) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2004.04.001 · Cited by 39

Complete DNA Sequence Variation in the Apolipoprotein H (β2‐glycoprotein I) Gene and Identification of Informative SNPs

Chen, Q., & Kamboh, M. I. (2005) · Annals of Human Genetics · doi:10.1111/j.1529-8817.2005.00211.x · Cited by 31

Genetic tests of biologic systems in affective disorders

Hattori, E., Liu, C., Zhu, H., & Gershon, E. S. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001695 · Cited by 31

Chipping away at complex behavior: Transcriptome/phenotype correlations in the mouse brain

Carter, T. A., Rio, J. A. D., Greenhall, J. A., Latronica, M. L., Lockhart, D. J., & Barlow, C. (2001) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00522-4 · Cited by 31

Design Considerations for Genetic Linkage and Association Studies

Nsengimana, J., & Bishop, D. T. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7274-6_13 · Cited by 31

Adaptive Two-Stage Analysis of Genetic Association in Case-Control Designs

Zheng, G., Song, K. S., & Elston, R. C. (2007) · Human Heredity · doi:10.1159/000099830 · Cited by 30

Association mapping of segregating sites in the early trypsin gene and susceptibility to dengue-2 virus in the mosquito Aedes aegypti

Gorrochótegui-Escalante, N., Lozano‐Fuentes, S., Bennett, K. E., Molina-Cruz, A., Beaty, B. J., & BlackIV, W. C. (2005) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2005.02.015 · Cited by 29

Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies

Lillioja, S., & Wilton, A. N. (2009) · Diabetologia · doi:10.1007/s00125-009-1324-9 · Cited by 30

Established and emerging strategies to crack the genetic code of obesity

Tam, V., Turcotte, M., & Meyre, D. (2018) · Obesity Reviews · doi:10.1111/obr.12770 · Cited by 31

Penetrance and Expressivity of Genes Involved in the Development of Epilepsy in the Genetically Epilepsy-Prone Rat (GEPR)

Kurtz, B., Lehman, J. M., Garlick, P., Amberg, J., Mishra, P. K., Dailey, J. W., Weber, R. J., & Jobe, P. C. (2001) · Journal of Neurogenetics · doi:10.3109/01677060109167379 · Cited by 30

Ecogeographic and genetic determinants of kernel weight and colour of wild barley (Hordeum spontaneum) populations in Israel

Chen, G., Suprunova, T. P., Krugman, T., Fahima, T., & Nevo, E. (2004) · Seed Science Research · doi:10.1079/ssr2004163 · Cited by 30

O papel do gene e da molécula HLA-G na expressão clínica das doenças reumatológicas

Brenol, C. V., Veit, T. D., Chies, J. A. B., & Xavier, R. M. (2012) · Revista Brasileira de Reumatologia · doi:10.1590/s0482-50042012000100009 · Cited by 30

Possible evidence for a common risk locus for bipolar affective disorder and schizophrenia on chromosome 4p16 in patients from the Faroe Islands

Als, T. D., Dahl, H. A., Flint, T. J., Wang, A. G., Vang, M., Mors, O. N., Kruse, T. A., & Ewald, H. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001393 · Cited by 30

Post-genome respiratory epidemiology: a multidisciplinary challenge

Kauffmann, F., & the Post Genome Respiratory Epidemiology group (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00076803 · Cited by 29

A Role for XRCC4 in Age at Diagnosis and Breast Cancer Risk

Allen‐Brady, K., Cannon‐Albright, L., Neuhausen, S. L., & Camp, N. J. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0959 · Cited by 30

The Genome Assembly Archive: A New Public Resource

Salzberg, S. L., Church, D. M., DiCuccio, M. N., Yaschenko, E., & Ostell, J. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020285 · Cited by 30

Genomes, Transcriptomes, and Proteomes

Gerling, I., Solomon, S. S., & Bryer‐Ash, M. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.2.190 · Cited by 30

Applying a new generation of genetic maps to understand human inflammatory disease

Hafler, D. A., & Jager, P. L. D. (2005) · Nature reviews. Immunology · doi:10.1038/nri1532 · Cited by 31

A Genomewide Screen in a Four-Generation Dutch Family with Celiac Disease: Evidence for Linkage to Chromosomes 6 and 9

van Belzen, M. J., Vrolijk, M. M., Meijer, J. W. R., Crusius, J. B. A., Pearson, P. L., Sandkuijl, L. A., Houwen, R. H. J., & Wijmenga, C. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04072.x · Cited by 30

Image-activated cell sorting

Ding, T., Lee, K. C. M., Tsia, K. K., Siegel, T. N., Carlo, D. D., & Goda, K. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00334-1 · Cited by 28

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Lee, J. H., Barral, S., Cheng, R., Chacón, I. J., Santana, V., Williamson, J., Lantigua, R., Medrano, M. A., Jiménez‐Velázquez, I. Z., Stern, Y., et al. (2007) · Neurogenetics · doi:10.1007/s10048-007-0103-3 · Cited by 29

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Mattarucchi, E., Marsoni, M., Binelli, G., Passi, A. G., Curto, F. L., Pasquali, F., & Porta, G. (2005) · BMB Reports · doi:10.5483/bmbrep.2005.38.5.555 · Cited by 29

Identification of single-nucleotide polymorphisms in the human N-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia

Makino, C., Shibata, H., Ninomiya, H., Tashiro, N., & Fukumaki, Y. (2005) · Psychiatric Genetics · doi:10.1097/00041444-200509000-00014 · Cited by 29

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Marigorta, U. M., Lao, Ó., Casals, F., Calafell, F., Morcillo-Suárez, C., Faria, R., Bosch, E., Serra, F., Bertranpetit, J., Dopazo, H., et al. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-55 · Cited by 32

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Dean, M. C. (2003) · Human Mutation · doi:10.1002/humu.10259 · Cited by 91

Dialogues Clin. Neurosci.

Ropers, H. (2010) · MPG.PuRe (Max Planck Society)

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Bamshad, M. J., Nickerson, D. A., & Chong, J. X. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.07.011 · Cited by 253

The strategy of gene mapping and the approach to genome wide search for human genetic diseases

An, Z. (2001) · Chinese Journal of Disease Control and Prevention