Searching for genetic determinants in the new millennium

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Botstein, D., White, R. L., Skolnick, M. H., & Davis, R. W. (1980) · Europe PMC (PubMed Central) · Cited by 8,327

The Future of Genetic Studies of Complex Human Diseases

Risch, N., & Merikangas, K. (1996) · Science · doi:10.1126/science.273.5281.1516 · Cited by 5,355

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

Lander, E. S., & Kruglyak, L. (1995) · Nature Genetics · doi:10.1038/ng1195-241 · Cited by 5,236

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Spielman, R. S., McGinnis, R. E., & Ewens, W. J. (1993) · PubMed · Cited by 3,679

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R., Ellis, M. C., Fullan, A., et al. (1996) · Nature Genetics · doi:10.1038/ng0896-399 · Cited by 3,664

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

Weber, J. L., & May, P. E. (1989) · Europe PMC (PubMed Central) · Cited by 3,399

Genomic Control for Association Studies

Devlin, B., & Roeder, K. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.00997.x · Cited by 3,162 · cited 1×

A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.

Litt, M., & Luty, J. A. (1989) · PubMed · Cited by 1,962

Sequential tests for the detection of linkage.

Morton, N. E. (1955) · PubMed · Cited by 1,590

An introduction to genetic statistics

Kempthorne, O. (1957) · Medical Entomology and Zoology · Cited by 1,552

Firing up the nature/nurture controversy: bioethics and genetic determinism

de Melo‐Martín, I. (2005) · Journal of Medical Ethics · doi:10.1136/jme.2004.008417 · Cited by 29

Three allele combinations associated with Multiple Sclerosis

Favorova, O. O., Favorov, A. V., Boiko, A. N., Andreewski, T. V., Sudomoina, M. A., Alekseenkov, A. D., Кулакова, О. Г., Gusev, E. I., Parmigiani, G., & Ochs, M. F. (2006) · BMC Medical Genetics · doi:10.1186/1471-2350-7-63 · Cited by 29

Endothelial nitric oxide synthase Glu298→Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample

Wolff, B., Braun, C., Schlüter, C., Grabe, H. J., Popowski, K., Völzke, H., Lüdemann, J., John, U., & Cascorbi, I. (2005) · Clinical Science · doi:10.1042/cs20050090 · Cited by 29

Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia

Underwood, S., Christoforou, A., Thomson, P. A., Wray, N. R., Tenesa, A., Whittaker, J. C., Adams, R. R., Hellard, S. L., Morris, S. W., Blackwood, D., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001786 · Cited by 29

Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap project

Nannya, Y., Taura, K., Kurokawa, M., Chiba, S., & Ogawa, S. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm205 · Cited by 30

Searching for susceptibility genes in schizophrenia

Jurewicz, I., Owen, R. J., O’Donovan, M. C., & Owen, M. J. (2001) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(01)00116-x · Cited by 29

Linkage disequilibrium analysis of the dopamine beta-hydroxylase gene in persistent attention deficit hyperactivity disorder

Inkster, B., Muglia, P., Jain, U., & Kennedy, J. (2004) · Psychiatric Genetics · doi:10.1097/01.ypg.0000107932.32051.1c · Cited by 31

A new gene for asthma: would you ADAM and Eve it?

Cookson, W. (2003) · Trends in Genetics · doi:10.1016/s0168-9525(03)00025-8 · Cited by 29

Genetics of Diabetic Nephropathy: Are There Clues to the Understanding of Common Kidney Diseases?

Conway, B. R., & Maxwell, A. P. (2009) · Nephron Clinical Practice · doi:10.1159/000224787 · Cited by 28

Accounting for Relatedness in Family Based Genetic Association Studies

McArdle, P. F., O’Connell, J. R., Pollin, T. I., Baumgarten, M., Shuldiner, A. R., Peyser, P. A., & Mitchell, B. D. (2007) · Human Heredity · doi:10.1159/000103861 · Cited by 28

The Predominance of the Environment over Genes in Cancer Causation: Implications for Genetic Epidemiology

Marchand, L. L. (2005) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-04-0816 · Cited by 28

The Quantitative and Molecular Genetics of Individual Differences in Animal Personality

Laine, V. N., & van Oers, K. (2017) · Springer eBooks · doi:10.1007/978-3-319-59300-5_4 · Cited by 29

Spectrum of Nonrandom Associations Between Microsatellite Loci on Human Chromosome 11p15

Zapata, C., Rodrı́guez, S., Visedo, G., & Sacristán, F. (2001) · Genetics · doi:10.1093/genetics/158.3.1235 · Cited by 27

The genetics of autoimmune thyroid disease

Ayadi, H., Kacem, H. H., Rebaï, A., & Farid, N. R. (2004) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2004.05.002 · Cited by 28

Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons

Wang, Q. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh121 · Cited by 28

Familial Aggregation of Lone atrial Fibrillation in the Chinese Population

Yang, Y., Zhang, X.-L., Wang, X., Tan, H., Shi, H., Fang, W., & Liu, X. (2010) · Internal Medicine · doi:10.2169/internalmedicine.49.4130 · Cited by 27

Computational Approaches and Resources in Single Amino Acid Substitutions Analysis Toward Clinical Research

Doss, C. G. P., Chakraborty, C., Narayan, V., & Kumar, D. T. (2014) · Advances in protein chemistry and structural biology · doi:10.1016/b978-0-12-800168-4.00010-x · Cited by 27

Association between a polymorphism of the vasopressin 1B receptor gene and aggression in children

Luppino, D., Moul, C., Hawes, D. J., Brennan, J., & Dadds, M. R. (2014) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000036 · Cited by 27

Pharmacogenetics in schizophrenia: a review of clozapine studies

Kohlrausch, F. B. (2013) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2012-0970 · Cited by 26

Molecular genetics of autism spectrum disorders

Shastry, B. S. (2003) · Journal of Human Genetics · doi:10.1007/s10038-003-0064-9 · Cited by 27

Microfluidic Platform for Single Nucleotide Polymorphism Genotyping of the Thiopurine S-Methyltransferase Gene to Evaluate Risk for Adverse Drug Events

Chowdhury, J., Kagiala, G. V., Pushpakom, S. P., Lauzon, J., Makin, A. J., Atrazhev, A. M., Stickel, A. J., Newman, W. G., Backhouse, C., & Pilarski, L. M. (2007) · Journal of Molecular Diagnostics · doi:10.2353/jmoldx.2007.070014 · Cited by 27

Genetics of age-related macular degeneration

KLEIN, M., & Francis, P. J. (2003) · Ophthalmology Clinics of North America · doi:10.1016/s0896-1549(03)00063-4 · Cited by 26

A new era in finding Type 2 diabetes genes—the unusual suspects

Frayling, T. M. (2007) · Diabetic Medicine · doi:10.1111/j.1464-5491.2007.02172.x · Cited by 28

High-Resolution Mapping for Essential Hypertension Using Microsatellite Markers

Yatsu, K., Mizuki, N., Hirawa, N., Oka, A., Ito, N., Yamane, T., Ogawa, M., Shiwa, T., Tabara, Y., Ohno, S., et al. (2007) · Hypertension · doi:10.1161/01.hyp.0000257256.77680.02 · Cited by 27

Genetic polymorphisms in susceptibility to Type 1 Diabetes

Alizadeh, B. Z., & Koeleman, B. P. C. (2007) · Clinica Chimica Acta · doi:10.1016/j.cca.2007.09.021 · Cited by 27

Candidate gene approach for pharmacogenetic studies

Ring, H. Z., & Kroetz, D. L. (2002) · Pharmacogenomics · doi:10.1517/14622416.3.1.47 · Cited by 27

Genomic aspects of sporadic neurodegenerative diseases

Mitsui, J., & Tsuji, S. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.07.098 · Cited by 27

Preferential transmission of type 1 diabetes from parents to offspring: fact or artifact?

Guo, S., & Tuomilehto, J. O. (2002) · Genetic Epidemiology · doi:10.1002/gepi.10183 · Cited by 26

Improving Power for Testing Genetic Association in Case–Control Studies by Reducing the Alternative Space

Joo, J., Kwak, M., & Zheng, G. (2009) · Biometrics · doi:10.1111/j.1541-0420.2009.01241.x · Cited by 26

A sequence-specific DNA sensor for Hepatitis B virus diagnostics based on the host–guest recognition

Zheng, J., Chen, C., Wang, X., Zhang, F., & He, P. (2014) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2014.03.110 · Cited by 26

Societal development and the shifting influence of the genome on status attainment

Adkins, D. E., & Guo, G. (2008) · Research in Social Stratification and Mobility · doi:10.1016/j.rssm.2008.06.001 · Cited by 26

Chronic Health Conditions in Childhood Cancer Survivors: Is it All Treatment-Related—or Do Genetics Play a Role?

Armenian, S. H., & Bhatia, R. (2009) · Journal of General Internal Medicine · doi:10.1007/s11606-009-0995-8 · Cited by 27

The identification of novel and differentially expressed apple-tree genes under low-temperature stress using high-throughput Illumina sequencing

Du, F., Xu, J., Li, D., & Wang, X. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3802-5 · Cited by 26

Paediatric pharmacogenomics: an overview

Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2012) · Archives of Disease in Childhood · doi:10.1136/archdischild-2012-302852 · Cited by 26

Family-Based Samples Can Play an Important Role in Genetic Association Studies

Lange, E. M., Sun, J., Lange, L. A., Zheng, S. L., Duggan, D. J., Carpten, J. D., Grönberg, H., Isaacs, W. B., Xu, J., & Chang, B. (2008) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0183 · Cited by 24

qNCLB7.02, a novel QTL for resistance to northern corn leaf blight in maize

Wang, J., Xu, Z., Yang, J., Lu, X., Zhou, Z., Zhang, C., Zheng, L., Tian, R., Hao, Z., Yong, H., et al. (2018) · Molecular Breeding · doi:10.1007/s11032-017-0770-1 · Cited by 26

How bioinformatics can help reverse engineer human aging

DEMAGALHAES, J., & Toussaint, O. (2004) · Ageing Research Reviews · doi:10.1016/j.arr.2003.08.006 · Cited by 27

Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia

van der Vleuten, G. M., Isaacs, A. J., Zeng, W., ter Avest, E., Talmud, P. J., Dallinga‐Thie, G. M., van Duijn, C. M., Stalenhoef, A. F. H., & Graaf, J. D. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.10.012 · Cited by 27

Type 2 diabetes and the genetics of signal transduction: A study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms

Bottini, N., Gloria‐Bottini, F., Borgiani, P., Antonacci, E., Lucarelli, P., & Bottini, E. (2004) · Metabolism · doi:10.1016/j.metabol.2004.03.006 · Cited by 26

Advances in statistical human genetics over the last 25 years

Elston, R. C., & Spence, M. A. (2006) · Statistics in Medicine · doi:10.1002/sim.2650 · Cited by 26

Assessing the quality of case-control association studies on the genetic basis of sepsis

Vitali, S. H., & Randolph, A. G. (2005) · Pediatric Critical Care Medicine · doi:10.1097/01.pcc.0000161572.12676.91 · Cited by 24

Genome Survey for Loci That Influence Successful Aging: Sample Characterization, Method Validation, and Initial Results for the Y Chromosome

Zubenko, G. S., Stiffler, J. S., Hughes, H. B., Fatigati, M. J., & Zubenko, W. N. (2002) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200209000-00016 · Cited by 26

Supervised learning-based tagSNP selection for genome-wide disease classifications

Liu, Q., Yang, J. Y., Chen, Z., Yang, M. Q., Sung, A. H., & Huang, X. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-s1-s6 · Cited by 26

Compendium of genome-wide scans of lipid-related phenotypes

Bossé, Y., Chagnon, Y. C., Després, J., Rice, T., Rao, D. C., Bouchard, C., Përusse, L., & Vohl, M. (2004) · Journal of Lipid Research · doi:10.1194/jlr.r400008-jlr200 · Cited by 26

Invited Commentary: Testing for Hardy-Weinberg Disequilibrium Using a Genome Single-Nucleotide Polymorphism Scan Based on Cases Only

Weinberg, C. R. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwg151 · Cited by 26

Unveiling the mysteries of the genetics of osteoporosis

Alonso, N., & Ralston, S. H. (2014) · Journal of Endocrinological Investigation · doi:10.1007/s40618-014-0149-7 · Cited by 25

Design Considerations for Genetic Linkage and Association Studies

Nsengimana, J., & Bishop, D. T. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-555-8_13 · Cited by 27

An Overview of Association Mapping

Oraguzie, N. C., & Wilcox, P. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-36011-9_1 · Cited by 28

The “Missing Heritability” of Psychiatric Disorders: Elusive Genes or Non-Existent Genes?

Joseph, J. (2012) · Applied Developmental Science · doi:10.1080/10888691.2012.667343 · Cited by 26

Child and adolescent psychiatric genetics

Hebebrand, J., Scherag, A., SCHIMMELMANN, B. G., & Hinney, A. (2010) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-010-0091-y · Cited by 25

Polymorphisms of cell cycle control genes influence the development of sporadic medullary thyroid carcinoma

Barbieri, R. B., Búfalo, N. E., Secolin, R., da Assumpção, L. V. M., Maciel, R. M. B., Cerutti, J. M., & Ward, L. S. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0461 · Cited by 26

Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women

Gaudet, M. M., Chanock, S. J., Lissowska, J., Berndt, S. I., Yang, X. R., Pepłońska, B., Brinton, L. A., Welch, R., Yeager, M., Bardin‐Mikolajczak, A., et al. (2006) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000215067.29342.6f · Cited by 25

The role of Self‐Defined Race/Ethnicity in Population Structure Control

Liu, X.-Q., Paterson, A., John, E., & Knight, J. (2006) · Annals of Human Genetics · doi:10.1111/j.1469-1809.2005.00255.x · Cited by 28

The IgA nephropathy Biobank. An important starting point for the genetic dissection of a complex trait

Schena, F. P., Cerullo, G., Torres, D. D., Scolari, F., Foramitti, M., Amoroso, A., Pirulli, D., Floege, J., Mertens, P. R., Zerres, K., et al. (2005) · BMC Nephrology · doi:10.1186/1471-2369-6-14 · Cited by 25

The Genetics of Atrial Fibrillation

Ellinor, P. T., & MacRae, C. A. (2003) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2003.03307.x · Cited by 25

Comparison of population‐ and family‐based methods for genetic association analysis in the presence of interacting loci

Howson, J. M. M., Barratt, B. J., Todd, J. A., & Cordell, H. J. (2005) · Genetic Epidemiology · doi:10.1002/gepi.20077 · Cited by 25

Genetic susceptibility to obstructive sleep apnea in the obese child

Kalra, M., & Chakraborty, R. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2006.09.003 · Cited by 25

PlantQTL-GE: a database system for identifying candidate genes in rice and Arabidopsis by gene expression and QTL information

Zeng, H., Luo, L., Zhang, W., Zhou, J. Y., Li, Z., Liu, H., Zhu, T., Feng, X., & Zhong, Y. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl814 · Cited by 25

Genetic Susceptibility, HIV Infection, and the Kidney

Kiryluk, K., Martino, J., & Gharavi, A. G. (2007) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.00320107 · Cited by 25

Effects of Natural Selection on Interpopulation Divergence at Polymorphic Sites in Human Protein-Coding Loci

Hughes, A. L., Packer, B. R., Welch, R. A., Bergen, A. W., Chanock, S. J., & Yeager, M. (2005) · Genetics · doi:10.1534/genetics.104.037077 · Cited by 25

Endothelial nitric oxide synthase T-786C polymorphism in rheumatoid arthritis: association with extraarticular manifestations

Brenol, C. V., Chies, J. A. B., Brenol, J. C. T., Monticielo, O. A., Franciscatto, P. C., Birriel, F. C., Neves, A. G., & Xavier, R. M. (2008) · Clinical Rheumatology · doi:10.1007/s10067-008-1018-6 · Cited by 24

Candidate Gene Approach to Identify Genes Underlying Quantitative Traits and Develop Diagnostic Markers in Potato

Gebhardt, C., Li, L., Pajerowska‐Mukthar, K., Achenbach, U., Sattarzadeh, A., Bormann, C. A., Ilarionova, E., & Ballvora, A. (2007) · Crop Science · doi:10.2135/cropsci2007.04.0005ipbs · Cited by 24

Functional polymorphism of human glutathione transferase A3: effects on xenobiotic metabolism and steroid biosynthesis.

Tetlow, N., Coggan, M., Casarotto, M., & P. Board (2004) · Pharmacogenetics (London) · doi:10.1097/00008571-200410000-00003 · Cited by 27

Statistical assessment of functional categories of genes deregulated in pathological conditions by using microarray data

Maglietta, R., Piepoli, A., Catalano, D., Licciulli, F., Carella, M., Liuni, S., Pesole, G., Perri, F., & Ancona, N. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm289 · Cited by 24

The Genetics and Development of Scoliosis

Kusumi, K., & Dunwoodie, S. L. (2009) · Springer eBooks · doi:10.1007/978-1-4419-1406-4 · Cited by 25

Design and analysis in genetic studies of human ageing and longevity

Tan, Q., Kruse, T. A., & Christensen, K. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.10.002 · Cited by 25

Simple association analysis combining data from trios/sibships and unrelated controls

Chen, Y., & Lin, H. (2008) · Genetic Epidemiology · doi:10.1002/gepi.20325 · Cited by 24

QuickSNP: an automated web server for selection of tagSNPs

Grover, D., Woodfield, A. S., Verma, R., Zandi, P. P., Levinson, D. F., & Potash, J. B. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm329 · Cited by 24

A genotyping strategy based on incorporation and cleavage of chemically modified nucleotides

Wolfe, J. L., Kawate, T., Sarracino, D. A., Zillmann, M., Olson, J. D., Stanton, V. P., & Verdine, G. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162346699 · Cited by 24

Genetics of Atrial Fibrillation

Lubitz, S. A., Yi, B. A., & Ellinor, P. T. (2008) · Cardiology Clinics · doi:10.1016/j.ccl.2008.09.007 · Cited by 25

Methyl-CpG Binding Domain 1Gene Polymorphisms and Risk of Primary Lung Cancer

Jang, J.-S., Lee, S. J., Choi, J. E., Ick, S., Lee, E. B., Park, T. I., Kim, C. H., Lee, W. K., Kam, S., Choi, J., et al. (2005) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0423 · Cited by 24

The genetics of alopecia areata

Aita, V. M., & Christiano, A. M. (2001) · Dermatologic Therapy · doi:10.1046/j.1529-8019.2001.01041.x · Cited by 24

Single nucleotide polymorphisms (SNPs) are inherited from parents and they measure heritable events.

Hemminki, K., Försti, A., & Bermejo, J. L. (2005) · Journal of Carcinogenesis · doi:10.1186/1477-3163-4-2 · Cited by 24

Genetic Analysis of Multiple Sclerosis in Europeans

Barcellos, L. F., & Thomson, G. (2003) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2003.08.004 · Cited by 25

Score test for detecting linkage to complex traits in selected samples

Lebrec, J., Putter, H., & van Houwelingen, H. C. (2004) · Genetic Epidemiology · doi:10.1002/gepi.20012 · Cited by 24

Quantitative Similarity-Based Association Tests Using Population Samples

Zhang, S., & Zhao, H. (2001) · The American Journal of Human Genetics · doi:10.1086/323037 · Cited by 24

Clinical Trials in Cardiovascular Medicine in an Era of Marginal Benefit, Bias, and Hyperbole

Loscalzo, J. (2005) · Circulation · doi:10.1161/circulationaha.105.594614 · Cited by 24

Functional Marker Development Across Species in Selected Traits

Cardoso, H. G., & Arnholdt‐Schmitt, B. (2013) · Springer eBooks · doi:10.1007/978-94-007-5687-8_21 · Cited by 23

Persistence Criteria for Susceptibility Genes for Schizophrenia: a Discussion from an Evolutionary Viewpoint

Doi, N., Hoshi, Y., Itokawa, M., Usui, C., Yoshikawa, T., & Tachikawa, H. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007799 · Cited by 26

Genome-Wide Association Studies and Colorectal Cancer

Marchand, L. L. (2009) · Surgical Oncology Clinics of North America · doi:10.1016/j.soc.2009.07.004 · Cited by 21

Sociological Ambivalence and the Order of Scientific Knowledge

Arribas‐Ayllon, M., & Bartlett, A. (2013) · Sociology · doi:10.1177/0038038513477937 · Cited by 23

Genetic epidemiology of bipolar disorder

Merikangas, K. R., & Yu, K. J. (2002) · Clinical Neuroscience Research · doi:10.1016/s1566-2772(02)00038-5 · Cited by 23

Genetics of Allergic Disease

Steinke, J. W., & Borish, L. (2006) · Medical Clinics of North America · doi:10.1016/j.mcna.2005.08.005 · Cited by 23

655Val and 1170Pro ERBB2 SNPs in Familial Breast Cancer Risk and BRCA1 Alterations

Tommasi, S., Fedele, V., Lacalamita, R., Bruno, M., Schittulli, F., Ginzinger, D. G., Scott, G., Eppenberger‐Castori, S., Calistri, D., Casadei, S., et al. (2007) · Analytical Cellular Pathology · doi:10.1155/2007/512518 · Cited by 23

Genome-wide association studies: progress in identifying genetic biomarkers in common, complex diseases.

Kingsmore, S. F., Lindquist, I. E., Mudge, J., & Beavis, W. D. (2007) · PubMed Central · Cited by 23

Confirmation of the DRB1-DQB1 loci as the major component of IDDM1 in the isolated founder population of Sardinia

Zavattari, P. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.20.2967 · Cited by 23

Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia

Lilja, H. E., Suviolahti, E., Soro‐Paavonen, A., Hiekkalinna, T., Day, A., Lange, K. L., Sobel, E. M., Taskinen, M., Peltonen, L., Perola, M., et al. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400141-jlr200 · Cited by 23

Genewindow: an interactive tool for visualization of genomic variation

Staats, B. J., Qi, L., Beerman, M. B., Sicotte, H., Burdett, L. A., Packer, B. R., Chanock, S. J., & Yeager, M. (2005) · Nature Genetics · doi:10.1038/ng0205-109 · Cited by 23

Association mapping of complex diseases in linked regions: estimation of genetic effects and feasibility of testing rare variants

Wang, W. Y. S., Cordell, H. J., & Todd, J. A. (2002) · Genetic Epidemiology · doi:10.1002/gepi.10216 · Cited by 23

Development of novel biomedicine based on genome science

Baba, Y. (2001) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(00)00201-3 · Cited by 23

Application of genomics and proteomics in Type 1 diabetes pathogenesis research

Sparre, T., Bergholdt, R., Nerup, J., & Pociot, F. (2003) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.3.6.743 · Cited by 24

Correspondence analysis of microarray time-course data in case–control design

Tan, Q., Brusgaard, K., Kruse, T. A., Oakeley, E. J., Hemmings, B. A., Beck‐Nielsen, H., Hansen, L., & Gaster, M. (2004) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2004.06.001 · Cited by 23

Regulatory Rewiring in a Cross Causes Extensive Genetic Heterogeneity

Matsui, T., Linder, R. A., Phan, J. L., Seidl, F., & Ehrenreich, I. M. (2015) · Genetics · doi:10.1534/genetics.115.180661 · Cited by 22

Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses

Feldmann, M. J., Piepho, H., Bridges, W. C., & Knapp, S. J. (2021) · PLoS Genetics · doi:10.1371/journal.pgen.1009762 · Cited by 21

Current status of predictive biomarkers for neoadjuvant therapy in esophageal cancer

Uemura, N., & Kondo, T. (2014) · World Journal of Gastrointestinal Pathophysiology · doi:10.4291/wjgp.v5.i3.322 · Cited by 22

Apolipoprotein E ε4 Allele was Associated With Nonlesional Mesial Temporal Lobe Epilepsy in Han Chinese Population

Li, Z., Ding, C., Gong, X., Wang, X., & Cui, T. (2016) · Medicine · doi:10.1097/md.0000000000002894 · Cited by 22

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