WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra

A theory of biological pattern formation

Gierer, A., & Meinhardt, H. (1972) · Kybernetik · doi:10.1007/bf00289234 · Cited by 3,158

Wnt signaling: a common theme in animal development

Cadigan, K. M., & Nusse, R. (1997) · Genes & Development · doi:10.1101/gad.11.24.3286 · Cited by 2,567

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destrée, O., & Clevers, H. (1996) · Cell · doi:10.1016/s0092-8674(00)80112-9 · Cited by 1,824

Evidence for a clade of nematodes, arthropods and other moulting animals

Aguinaldo, A. M. A., Turbeville, J. M., Linford, L. S., Rivera, M. C., Garey, J. R., Raff, R. A., & Lake, J. A. (1997) · Nature · doi:10.1038/387489a0 · Cited by 1,609

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.

Wetering, M. L. V. D., Cavallo, R. A., Dooijes, D., van Beest, M., van Es, J. V., Loureiro, J., Ypma, A., Hursh, D., Jones, T. L., Bejsovec, A., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)81925-x · Cited by 1,347

Animal evolution: interrelationships of the living phyla

(2012) · Choice Reviews Online · doi:10.5860/choice.50-1469 · Cited by 1,041

Principles of Development

Wolpert, L., Tickle, C. A., Arias, A. M., Lawrence, P. A., & Locke, J. C. W. (2019) · Oxford University Press eBooks · doi:10.1093/hesc/9780198800569.001.0001 · Cited by 991

Early animal evolution: emerging views from comparative biology and geology

Knoll, A. H., & Carroll, S. B. (1999) · Science · doi:10.1126/science.284.5423.2129 · Cited by 821

Principles of Development

Webster, S. (2018) · doi:10.1002/9781394322084.ch1 · Cited by 786

PCR primer: a laboratory manual.

Dieffenbach, C. W., & Dveksler, G. S. (2003) · Cited by 733

The evolution and development of coloniality in hydrozoans

Cartwright, P., Travert, M. K., & Sanders, S. M. (2020) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.22996 · Cited by 22

The Life Cycle of Aurelia aurita Depends on the Presence of a Microbiome in Polyps Prior to Onset of Strobilation

Jensen, N., Weiland‐Bräuer, N., Joel, S., Chibani, C. M., & Schmitz, R. A. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.00262-23 · Cited by 26

From Sphere to Torus: A Topological View of the Metazoan Body Plan

Jockusch, H. (2003) · Bulletin of Mathematical Biology · doi:10.1006/bulm.2002.0319 · Cited by 22

Preparation Techniques for Transmission Electron Microscopy of Hydra

Holstein, T. W., Hess, M. W., & Salvenmoser, W. (2010) · Methods in cell biology · doi:10.1016/s0091-679x(10)96013-5 · Cited by 22

Cloning and characterisation of PKB and PRK homologs from Hydra and the evolution of the protein kinase family

Herold, M., Cikala, M., MacWilliams, H. K., David, C. N., & Böttger, A. (2002) · Development Genes and Evolution · doi:10.1007/s00427-002-0267-7 · Cited by 22

A WNTer wonderland in Snowbird

He, X., & Axelrod, J. D. (2006) · Development · doi:10.1242/dev.02452 · Cited by 22

Models for the generation of the embryonic body axes: ontogenetic and evolutionary aspects

Meinhardt, H. (2004) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2004.06.012 · Cited by 22

Selective inhibition of protein kinases blocks the formation of a new axis, the beginning of budding, in Hydra

Fabila, Y., Navarro, L., Fujisawa, T., Bode, H. R., & Salgado, L. M. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00351-9 · Cited by 22

A model for budding in hydra: pattern formation in concentric rings

Berking, S. (2003) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(03)00012-2 · Cited by 22

On some features of embryonic development and metamorphosis of Aurelia aurita (Cnidaria, Scyphozoa)

Mayorova, T. D., Kosevich, I. A., & Melekhova, O. P. (2012) · Russian Journal of Developmental Biology · doi:10.1134/s1062360412050050 · Cited by 21

Dysregulation of the Wnt/β-Catenin Signaling Pathway in Canine Cutaneous Melanotic Tumor

Han, J.-I., Kim, D.-Y., & Na, K. (2009) · Veterinary Pathology · doi:10.1177/0300985809359303 · Cited by 21

Critical Behavior and Axis Defining Symmetry Breaking inHydraEmbryonic Development

Gamba, A., Nicodemi, M., Soriano, J., & Ott, A. (2012) · Physical Review Letters · doi:10.1103/physrevlett.108.158103 · Cited by 21

The Rapid Regenerative Response of a Model Sea Anemone Species Exaiptasia pallida Is Characterised by Tissue Plasticity and Highly Coordinated Cell Communication

van der Burg, C. A., Pavasovic, A., Gilding, E. K., Pelzer, E., Surm, J. M., Smith, H. L., Walsh, T. P., & Prentis, P. J. (2020) · Marine Biotechnology · doi:10.1007/s10126-020-09951-w · Cited by 21

Expression of Wnt and TGF-Beta Pathway Components during Whole-Body Regeneration from Cell Aggregates in Demosponge Halisarca dujardinii

Borisenko, I., Bolshakov, F. V., Ereskovsky, A. V., & Lavrov, A. (2021) · Genes · doi:10.3390/genes12060944 · Cited by 21

CRH and SRIF Have Opposite Effects on the Wnt/β-Catenin Signalling Pathway Through PKA/GSK-3β in Corticotroph Pituitary Cells

Khattak, M. N. K., Buchfelder, M., Kleindienst, A., Schöfl, C., & Kremenevskaja, N. (2010) · Cancer Investigation · doi:10.3109/07357907.2010.494318 · Cited by 21

Activities of the protein kinases STK, PI3K, MEK, and ERK are required for the development of the head organizer in Hydra magnipapillata

Arvizu, F., Aguilera‐Méndez, A., & Salgado, L. M. (2006) · Differentiation · doi:10.1111/j.1432-0436.2006.00078.x · Cited by 21

Cloning of noggin gene from hydra and analysis of its functional conservation using Xenopus laevis embryos

Chandramore, K., Ito, Y., Takahashi, S., Asashima, M., & Ghaskadbi, S. (2010) · Evolution & Development · doi:10.1111/j.1525-142x.2010.00412.x · Cited by 20

Foot formation in Hydra: A novel gene, anklet, is involved in basal disk formation

Amimoto, Y., Kodama, R., & Kobayakawa, Y. (2006) · Mechanisms of Development · doi:10.1016/j.mod.2006.03.002 · Cited by 20

In vivo electroporation for genetic manipulations of whole Hydra polyps

Bosch, T. C. G., Augustin, R., Gellner, K., Khalturin, K., & Lohmann, J. U. (2002) · Differentiation · doi:10.1046/j.1432-0436.2002.700403.x · Cited by 20

How Somatic Adult Tissues Develop Organizer Activity

Vogg, M. C., Wenger, Y., & Galliot, B. (2016) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2015.11.002 · Cited by 19

Autoaggressive, multi-headed and other mutant phenotypes in Hydractinia echinata (Cnidaria: Hydrozoa)

Müller, W. A. (2002) · The International Journal of Developmental Biology · doi:10.1387/ijdb.12533026 · Cited by 20

Detection of Expression Patterns in Hydra Pattern Formation

Bode, H. R., Lengfeld, T., Hobmayer, B., & Holstein, T. W. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-469-2_7 · Cited by 20

The foot formation stimulating peptide pedibin is also involved in patterning of the head in hydra

Hoffmeister‐Ullerich, S. (2001) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00401-4 · Cited by 20

Crosstalk Between β-CATENIN-Mediated Cell Adhesion and the WNT Signaling Pathway

Liu, D.-X., Hao, S.-L., & Yang, W. (2022) · DNA and Cell Biology · doi:10.1089/dna.2022.0424 · Cited by 19

Evolution of Hox-like genes in Cnidaria: Study of Hydra Hox repertoire reveals tailor-made Hox-code for Cnidarians

Reddy, P. C., Unni, M., Gungi, A., Agarwal, P., & Galande, S. (2015) · Mechanisms of Development · doi:10.1016/j.mod.2015.08.005 · Cited by 19

Control of foot differentiation in Hydra: Phylogenetic footprinting indicates interaction of head, bud and foot patterning systems

Siebert, S., Thomsen, S., Reimer, M. M., & Bosch, T. C. G. (2005) · Mechanisms of Development · doi:10.1016/j.mod.2005.04.010 · Cited by 20

Hydra, a candidate for an alternative model in environmental genomics

Yum, S., Woo, S., Lee, A., Won, H., & Kim, J. (2014) · Molecular & Cellular Toxicology · doi:10.1007/s13273-014-0038-3 · Cited by 19

Important roles for epithelial cell peptides in hydra development

Takahashi, T., & Fujisawa, T. (2009) · BioEssays · doi:10.1002/bies.200800163 · Cited by 19

Planarian organizers

Sureda-Gómez, M., & Adell, T. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.05.021 · Cited by 18

Models for patterning primary embryonic body axes: The role of space and time

Meinhardt, H. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.06.005 · Cited by 19

A systematic review on toxicity assessment of persistent emerging pollutants (EPs) and associated microplastics (MPs) in the environment using the Hydra animal model

Vimalkumar, K., Sangeetha, S., LewisOscar, F., Kay, P., & Pugazhendhi, A. (2022) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2022.109320 · Cited by 19

The Hippo pathway regulates axis formation and morphogenesis in Hydra

Brooun, M., Salvenmoser, W., Dana, C. E., Sudol, M., Steele, R. E., Hobmayer, B., & McNeill, H. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2203257119 · Cited by 17

Confinement Modulates Axial Patterning in Regenerating Hydra

Maroudas-Sacks, Y., Garion, L., Suganthan, S., Popovic, M. A., & Keren, K. (2024) · PRX Life · doi:10.1103/prxlife.2.043007 · Cited by 18

Wnt affects symmetry and morphogenesis during post-embryonic development in colonial chordates

Maio, A. D., Setar, L., Tiozzo, S., & Tomaso, A. W. D. (2015) · EvoDevo · doi:10.1186/s13227-015-0009-3 · Cited by 18

Field and laboratory investigations of budding in the tetillid sponge Cinachyrella cavernosa

Singh, A., & Thakur, N. L. (2015) · Invertebrate Biology · doi:10.1111/ivb.12074 · Cited by 18

Differential regulation of myc homologs by Wnt/β‐Catenin signaling in the early metazoan Hydra

Hartl, M., Glasauer, S. M. K., Gufler, S., Raffeiner, A., Puglisi, K., Breuker, K., Bister, K., & Hobmayer, B. (2019) · FEBS Journal · doi:10.1111/febs.14812 · Cited by 18

Mouth Function Determines the Shape Oscillation Pattern in Regenerating Hydra Tissue Spheres

Wang, R., Goel, T., Khazoyan, K., Sabry, Z., Quan, H. J., Diamond, P. H., & Collins, E. S. (2019) · Biophysical Journal · doi:10.1016/j.bpj.2019.07.051 · Cited by 17

Expression of Wnt pathway genes in polyps and medusa‐like structures of Ectopleura larynx ( C nidaria: Hydrozoa)

Nawrocki, A. M., & Cartwright, P. (2013) · Evolution & Development · doi:10.1111/ede.12045 · Cited by 18

The Emergence of Pattern in Embryogenesis: Regulation of β-Catenin Localization During Early Sea Urchin Development

Ettensohn, C. A. (2006) · Science s STKE · doi:10.1126/stke.3612006pe48 · Cited by 18

Embryonic expression of priapulid Wnt genes

Hogvall, M., Vellutini, B. C., Martín-Durán, J. M., Hejnol, A., Budd, G. E., & Janßen, R. (2019) · Development Genes and Evolution · doi:10.1007/s00427-019-00636-6 · Cited by 17

Gene expression alterations from reversible to irreversible stages during coral metamorphosis

Ishii, Y., Hatta, M., Deguchi, R., Kawata, M., & Maruyama, S. (2022) · Zoological Letters · doi:10.1186/s40851-022-00187-1 · Cited by 17

Canalized Morphogenesis Driven by Inherited Tissue Asymmetries in Hydra Regeneration

Shani-Zerbib, L., Garion, L., Maroudas-Sacks, Y., Braun, E., & Keren, K. (2022) · Genes · doi:10.3390/genes13020360 · Cited by 17

Asymmetric requirement of surface epithelial β‐catenin during the upper and lower jaw development

Sun, Y., Teng, I., Huo, R., Rosenfeld, M. G., Olson, L. E., Li, X., & Li, X. (2012) · Developmental Dynamics · doi:10.1002/dvdy.23755 · Cited by 17

Epigenomic landscape of enhancer elements during Hydra head organizer formation

Reddy, P. C., Gungi, A., Ubhe, S., & Galande, S. (2020) · Epigenetics & Chromatin · doi:10.1186/s13072-020-00364-6 · Cited by 15

High regenerative capacity is a general feature within colonial dendrophylliid corals (Anthozoa, Scleractinia)

Luz, B. L. P., Miller, D. J., & Kitahara, M. V. (2021) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.23021 · Cited by 17

Wnt4, the first member of the Wnt family identified in Schistosoma japonicum, regulates worm development by the canonical pathway

Li, H., Wang, X., Jin, Y., Xia, Y., Feng, X., Yang, J., Qi, X., Yuan, C., & Lin, J. (2010) · Parasitology Research · doi:10.1007/s00436-010-1933-8 · Cited by 17

Expression of the AmphiTcf gene in amphioxus: Insights into the evolution of the TCF/LEF gene family during vertebrate evolution

Lin, H., Holland, L. Z., & Holland, N. D. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20971 · Cited by 17

Epigenetic Regulation in Hydra: Conserved and Divergent Roles

Pillai, A., Gungi, A., Reddy, P. C., & Galande, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.663208 · Cited by 16

Remote Magneto–Thermal Modulation of Reactive Oxygen Species Balance Enhances Tissue Regeneration In Vivo

Tommasini, G., Sol‐Fernández, S. D., Flavián‐Lázaro, A. C., Lewińska, A., Wnuk, M., Tortiglione, C., & Moros, M. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202405282 · Cited by 16

Identification and expression characterization of WntA during intestinal regeneration in the sea cucumber Apostichopus japonicus

Li, X., Sun, L., Yang, H., Zhang, L., Miao, T., Xing, L., & Huo, D. (2017) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2017.06.005 · Cited by 16

Extracellular matrix and morphogenesis in cnidarians: a tightly knit relationship

Bergheim, B. G., & Özbek, S. (2019) · Essays in Biochemistry · doi:10.1042/ebc20190021 · Cited by 16

Differential gene regulation in DAPT-treated Hydra reveals candidate direct Notch signalling targets

Moneer, J., Siebert, S., Krebs, S., Cazet, J. F., Prexl, A., Pan, Q., Juliano, C. E., & Böttger, A. (2021) · Journal of Cell Science · doi:10.1242/jcs.258768 · Cited by 13

Frizzled7 dictates embryonic morphogenesis: implications for colorectal cancer progression

Vincan, E. (2007) · Frontiers in bioscience · doi:10.2741/2410 · Cited by 16

Real time dynamics of β-catenin expression during Hydra development, regeneration and Wnt signalling activation

Iachetta, R., Ambrosone, A., Klimovich, A. V., Wittlieb, J., Onorato, G., Candeo, A., D’Andrea, C., Intartaglia, D., Scotti, N., Blasio, M., et al. (2018) · The International Journal of Developmental Biology · doi:10.1387/ijdb.180092ct · Cited by 16

сWnt signaling modulation results in a change of the colony architecture in a hydrozoan

Bagaeva, T. S., Kupaeva, D. M., Vetrova, A. A., Kosevich, I. A., Kraus, Y. A., & Kremnyov, S. V. (2019) · Developmental Biology · doi:10.1016/j.ydbio.2019.08.019 · Cited by 16

Cnidaria

Technau, U., Genikhovich, G., & Kraus, J. E. M. (2015) · Springer eBooks · doi:10.1007/978-3-7091-1862-7_6 · Cited by 17

Wound healing phytoconstituents from seed kernel of Entada pursaetha DC. and their molecular docking studies with glycogen synthase kinase 3-β

Vidya, S. M., Krishna, V., Manjunatha, B. K., Bharath, B. R., Rajesh, K. P.-G., Manjunatha, H., & Mankani, K. L. (2011) · Medicinal Chemistry Research · doi:10.1007/s00044-011-9860-5 · Cited by 16

Control of foot differentiation in Hydra: in vitro evidence that the NK-2 homeobox factor CnNK-2 autoregulates its own expression and uses pedibin as target gene

Thomsen, S., Till, A., Wittlieb, J., Beetz, C., Khalturin, K., & Bosch, T. C. G. (2004) · Mechanisms of Development · doi:10.1016/j.mod.2003.12.001 · Cited by 16

MAPK signaling links the injury response to Wnt-regulated patterning in Hydra regenerationPreprint

Tursch, A., Bartsch, N., & Holstein, T. W. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.06.189795 · Cited by 16

Hydra’s Lasting Partnership with Microbes: The Key for Escaping Senescence?

He, J., & Bosch, T. C. G. (2022) · Microorganisms · doi:10.3390/microorganisms10040774 · Cited by 15

Mechano-Chemical Coupling in Hydra Regeneration and Patterning

Wang, R., Bialas, A. L., Goel, T., & Collins, E. S. (2023) · Integrative and Comparative Biology · doi:10.1093/icb/icad070 · Cited by 15

Mechanochemical patterning localizes the organizer of a luminal epithelium

Weevers, S. L., Falconer, A. D., Mercker, M., Sadeghi, H., Rozema, D., Ferenc, J., Maître, J., Ott, A., Oelz, D., Marciniak-Czochra, A. K., et al. (2025) · Science Advances · doi:10.1126/sciadv.adu2286 · Cited by 15

Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates

Bailles, A., Serafini, G., Andreas, H., Zechner, C., Modes, C. D., & Tomančák, P. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2423437122 · Cited by 15

The putative Notch ligand HyJagged is a transmembrane protein present in all cell types of adult Hydra and upregulated at the boundary between bud and parent

Prexl, A., Münder, S., Loy, B., Kremmer, E., Tischer, S., & Böttger, A. (2011) · BMC Cell Biology · doi:10.1186/1471-2121-12-38 · Cited by 15

Combined exposure to big endothelin-1 and mechanical loading in bovine sternal cores promotes osteogenesis

Meyer, L. A., Johnson, M. G., Cullen, D. M., Vivanco, J. F., Blank, R. D., Ploeg, H., & Smith, E. L. (2016) · Bone · doi:10.1016/j.bone.2016.02.001 · Cited by 14

Environmental and molecular regulation of asexual reproduction in the sea anemone Nematostella vectensis

Al‐Shaer, L., Leach, W. B., Baban, N., Yagodich, M., Gibson, M. C., & Layden, M. J. (2023) · Royal Society Open Science · doi:10.1098/rsos.230152 · Cited by 14

On being a Hydra with, and without, a nervous system: what do neurons add?

Hanson, A. J. (2023) · Animal Cognition · doi:10.1007/s10071-023-01816-8 · Cited by 18

Phylogenetic Origins of Brain Organisers

Robertshaw, E., & Kiecker, C. M. (2012) · Scientifica · doi:10.6064/2012/475017 · Cited by 14

Genome-wide screening reveals the emergence and divergence of RTK homologues in basal Metazoan Hydra magnipapillata

Reddy, P. C., Bidaye, S. S., & Ghaskadbi, S. (2011) · Journal of Biosciences · doi:10.1007/s12038-011-9065-6 · Cited by 14

Branching in Colonial Hydroids

Kosevich, I. A. (2007) · Springer eBooks · doi:10.1007/0-387-30873-3_5 · Cited by 14

Animal development in the microbial world: The power of experimental model systems

McFall‐Ngai, M., & Bosch, T. C. G. (2020) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.10.002 · Cited by 14

Diversification of the Metazoa: Ediacarans, colonies, and the origin of eumetazoan complexity by nested modularity

Dewel, R. A., Dewel, W. C., & McKinney, F. K. (2001) · Historical Biology · doi:10.1080/10292380109380592 · Cited by 14

The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra

Vogg, M. C., Ferenc, J., Buzgariu, W. C., Perruchoud, C., Sanchez, P. G. L., Beccari, L. L., Nuninger, C., Cras, Y. L., Delucinge-Vivier, C., Papasaikas, P., et al. (2022) · Science Advances · doi:10.1126/sciadv.abo0694 · Cited by 13

The dynamic genomes of Hydra and the anciently active repeat complement of animal chromosomes

Kon‐Nanjo, K., Kon, T., Koubková-Yu, T. C.-T., Rodriguez‐Terrones, D., Falcon, F., Martínez, D. E., Steele, R. E., Tanaka, E. M., Holstein, T. W., & Simakov, O. (2025) · Genome biology · doi:10.1186/s13059-025-03653-z · Cited by 17

Establishing Bilateral Symmetry in Hydrozoan Planula Larvae, a Review of Siphonophore Early Development

Mańko, M. K., Munro, C., & Leclère, L. (2023) · Integrative and Comparative Biology · doi:10.1093/icb/icad081 · Cited by 13

Tracking mechanical and morphological dynamics of regenerating Hydra tissue fragments using a two fingered micro-robotic hand

Veschgini, M., Gebert, F., Khangai, N., Ito, H., Suzuki, R., Holstein, T. W., Mae, Y., Arai, T., & Tanaka, M. (2016) · Applied Physics Letters · doi:10.1063/1.4943402 · Cited by 13

Non-developmental dimensions of adult regeneration in Hydra

Galliot, B., Buzgariu, W., Schenkelaars, Q., & Wenger, Y. (2018) · The International Journal of Developmental Biology · doi:10.1387/ijdb.180111bg · Cited by 13

Regeneration inHydra

Galliot, B. (2013) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0001096.pub3 · Cited by 13

Stem cell differentiation trajectories in Hydra resolved at single-cell resolutionPreprint

Siebert, S., Farrell, J. A., Cazet, J. F., Abeykoon, Y., Primack, A. S., Schnitzler, C. E., & Juliano, C. E. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/460154 · Cited by 14

From injury to patterning—MAPKs and Wnt signaling in Hydra

Tursch, A., & Holstein, T. W. (2023) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2023.01.003 · Cited by 12

Hydra gasdermin-gated pyroptosis signalling regulates tissue regeneration

Chen, S., Gong, Y., Li, S., Yang, D., Zhang, Y., & Liu, Q. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.104904 · Cited by 12

Expression and molecular diversity of Tcf7l2 in the developing murine cerebellum and brain

Nazwar, T. A., Glassmann, A., & Schilling, K. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.21989 · Cited by 12

Fluctuations and differential contraction during regeneration ofHydra vulgaristissue toroids

Krahe, M., Wenzel, I., Lin, K.-N., Fischer, J., Goldmann, J., Kästner, M., & Fütterer, C. (2013) · New Journal of Physics · doi:10.1088/1367-2630/15/3/035004 · Cited by 12

Organizer regions in marine colonial hydrozoans

Mayorova, T. D., Kosevich, I. A., Dulin, N. O., Savina, E. O., & Kraus, Y. A. (2015) · Zoology · doi:10.1016/j.zool.2014.12.001 · Cited by 12

Modulation of Wnt signaling: A route to speciation?

Duffy, D. J. (2011) · Europe PMC (PubMed Central) · doi:10.4161/cib.4.1.13712 · Cited by 12

Mechanochemical induction of wrinkling morphogenesis on elastic shells

Zakharov, A. P., & Dasbiswas, K. (2021) · Soft Matter · doi:10.1039/d1sm00003a · Cited by 11

Wnt signaling in whole-body regeneration

Petersen, C. P. (2023) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2023.01.007 · Cited by 9

Musculature development in planuloids of Cassiopeia xamachana (Cnidaria: Scyphozoa)

Khabibulina, V., & Starunov, V. V. (2019) · Zoomorphology · doi:10.1007/s00435-019-00444-6 · Cited by 11

Modeling mechanochemical pattern formation in elastic sheets of biological matter

Zakharov, A. P., & Dasbiswas, K. (2021) · The European Physical Journal E · doi:10.1140/epje/s10189-021-00086-x · Cited by 11

Novel missense mutation in WNT6 in 100 couples with unexplained recurrent miscarriage

Zhang, Y., Li, G., Fan, Y., Cui, Y., Huang, S., Ma, J., Yan, J., & Chen, Z. (2015) · Human Reproduction · doi:10.1093/humrep/dev028 · Cited by 11

Glycogen Synthase Kinase 3β Inhibitor Delivered by Chitosan Nanocapsules Promotes Safe, Fast, and Efficient Activation of Wnt Signaling In Vivo

Ambrosone, A., Matteis, L. D., Serrano‐Sevilla, I., Tortiglione, C., & de la Fuente, J. M. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.9b01820 · Cited by 10

Excess hydrogen peroxide inhibits head and foot regeneration in hydra by affecting DNA repair and expression of essential genes

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