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Gene therapy: trials and tribulations

Somia, Nikunj, Verma, Inder M.·2000·Nature Reviews Genetics
DOI 10.1038/35038533
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Abstract

The art and science of gene therapy has received much attention of late. The tragic death of 18-year-old Jesse Gelsinger, a volunteer in a Phase I clinical trial, has overshadowed the successful treatment of three children suffering from a rare but fatal immunological disease. In the light of the success and tragedy, it is timely to consider the challenges faced by gene therapy--a novel form of molecular medicine that may be poised to have an important impact on human health in the new millennium.

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Authors
Somia, N., & Verma, I. M.
Venue
Nature Reviews Genetics
Publisher
Springer Science and Business Media LLC
Published
2000-11
Volume
1
Issue
2
Pages
91-99
ISSN
  • 1471-0056
  • 1471-0064
DOI
10.1038/35038533
Cited by
554
References
5
Language
en
Licence
www.springer.com/tdm (tdm)

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Somia, N., & Verma, I. M. (2000). Gene therapy: trials and tribulations. Nature Reviews Genetics. https://doi.org/10.1038/35038533