Phagocytosis and clearance of apoptotic cells is mediated by MER

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J., Bratton, D. L., & Henson, P. M. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.7.2207 · Cited by 3,321

Programmed Cell Death in Animal Development

Jacobson, M. D., Weil, M., & RAFF, M. C. (1997) · Cell · doi:10.1016/s0092-8674(00)81873-5 · Cited by 2,685

A receptor for phosphatidylserine-specific clearance of apoptotic cells

Fadok, V. A., Bratton, D. L., Rose, D. M., Pearson, A. M., Ezekowitz, R. A. B., & Henson, P. M. (2000) · Nature · doi:10.1038/35011084 · Cited by 1,491

Phagocyte recognition of cells undergoing apoptosis

Savill, J., Fadok, V. A., Henson, P. M., & Haslett, C. (1993) · Immunology Today · doi:10.1016/0167-5699(93)90215-7 · Cited by 981

Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat

D'Cruz, P. M. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.4.645 · Cited by 884

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

Savill, J., Dransfield, I., Hogg, N., & Haslett, C. (1990) · Nature · doi:10.1038/343170a0 · Cited by 846

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

Savill, J., Hogg, N., Ren, Y., & Haslett, C. (1992) · Journal of Clinical Investigation · doi:10.1172/jci116019 · Cited by 818

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

O’Bryan, J. P., Frye, R. A., Cogswell, P. C., Neubauer, A., Kitch, B., Prokop, C. A., Espinosa, R., Beau, M. M. L., Earp, H. S., & Liu, E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.10.5016 · Cited by 746

A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo

Taylor, P. R., Carugati, A., Fadok, V. A., Cook, H. T., Andrews, M., Carroll, M. C., Savill, J., Henson, P. M., Botto, M., & Walport, M. J. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.3.359 · Cited by 724

Human CD14 mediates recognition and phagocytosis of apoptotic cells

Devitt, A., Moffatt, O., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998) · Nature · doi:10.1038/33169 · Cited by 681

High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily

Wu, H., Tang, H., Chen, Y., Wang, H., & Han, D. (2008) · Molecular Reproduction and Development · doi:10.1002/mrd.20917 · Cited by 15

RhoA/Phosphatidylinositol 3-Kinase/Protein Kinase B/Mitogen-Activated Protein Kinase Signaling after Growth Arrest–Specific Protein 6/Mer Receptor Tyrosine Kinase Engagement Promotes Epithelial Cell Growth and Wound Repair via Upregulation of Hepatocyte Growth Factor in Macrophages

Lee, Y.-J., Park, H.-J., Woo, S., Park, E., & Kang, J. L. (2014) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.114.215673 · Cited by 15

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Microbes, apoptosis and TIM-1 in the development of asthma

Umetsu, D. T., & DeKruyff, R. H. (2010) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2010.04136.x · Cited by 15

Increased Hematopoietic Cells in the mertk−/− Mouse Peritoneal Cavity: A Result of Augmented Migration

Williams, J., Wagner, N. J., Earp, H. S., Vilen, B. J., & Matsushima, G. K. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902784 · Cited by 15

Vitamin K-dependent proteins: Functions in blood coagulation and beyond

Benzakour, O. (2008) · Thrombosis and Haemostasis · doi:10.1160/th08-07-0497 · Cited by 15

O death where is thy sting? Immunologic tolerance to apoptotic self

Ravishankar, B., & McGaha, T. L. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1261-0 · Cited by 16

An ENU-Induced Mutation in the Mertk Gene ( Mertk nmf12 ) Leads to a Slow Form of Retinal Degeneration

Maddox, D. M., Hicks, W. L., Vollrath, D., LaVail, M. M., Naggert, J. Κ., & Nishina, P. M. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-7077 · Cited by 15

Clinical trials in retinal dystrophies

Eliott, D., Grob, S., Finn, A. P., & Papakostas, T. (2016) · Middle East African Journal of Ophthalmology · doi:10.4103/0974-9233.173135 · Cited by 19

Co-receptors are dispensable for tethering receptor-mediated phagocytosis of apoptotic cells

Park, B., Lee, J., Moon, H., Lee, G., Lee, D., Cho, J. H., & Park, D. (2015) · Cell Death and Disease · doi:10.1038/cddis.2015.140 · Cited by 15

Anti-Sm B cell tolerance and tolerance loss in systemic lupus erythematosus

Clarke, S. H. (2008) · Immunologic Research · doi:10.1007/s12026-008-8023-3 · Cited by 15

Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans

Harley, I. T. W., Allison, K., & Scofield, R. H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.953439 · Cited by 15

Does Antigen Masking by Ubiquitin Chains Protect from the Development of Autoimmune Diseases?

Weil, R. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00262 · Cited by 14

Contribution of histidine-rich glycoprotein in clearance of immune complexes and apoptotic cells: Implications for ameliorating autoimmune diseases

Gorgani, N. N., & Theofilopoulos, A. N. (2007) · Autoimmunity · doi:10.1080/08916930701358883 · Cited by 14

Macrophage apoptosis in rat skeletal muscle treated with bupivacaine hydrochloride: Possible role of MCP‐1

堀口, 泰., Shibata, M., Ito, Y., Eid, N. A. S., Abe, M., & Otsuki, Y. (2002) · Muscle & Nerve · doi:10.1002/mus.10162 · Cited by 14

Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes

Wang, X., Malawista, A., Qian, F., Ramsey, C. N., Allore, H. G., & Montgomery, R. R. (2018) · Oncotarget · doi:10.18632/oncotarget.23851 · Cited by 14

Membrane receptor MerTK is a newly identified transcriptional regulator that associates to chromatin as nanoclusters during human DC differentiationPreprint

Borgman, K. J. E., Flórez‐Grau, G., Ricci, M. A., Manzo, C., Lakadamyali, M., Cambi, A., Benítez‐Ribas, D., Campelo, F., & Parajo, M. F. G. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.16.044974 · Cited by 13

Experimental Use of Murine Lupus Models

Peng, S. L. (2004) · Humana Press eBooks · doi:10.1385/1-59259-805-6:227 · Cited by 13

Involvement of Ran in the regulation of phagocytosis against virus infection in S2 cells

Ye, T., & Zhang, X. (2013) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2013.07.015 · Cited by 13

MafB enhances efferocytosis in RAW264.7 macrophages by regulating Axl expression

Sato, M., Shibata, Y., Inoue, S., Igarashi, A., Tokairin, Y., Yamauchi, K., Kimura, T., Nemoto, T., Sato, K., Nakano, H., et al. (2017) · Immunobiology · doi:10.1016/j.imbio.2017.10.007 · Cited by 13

Functional Genomics of the Retina to Elucidate its Construction and Deconstruction

Blond, F., & Léveillard, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194922 · Cited by 14

Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair

Ranta, A., & Kumar, S. (2020) · International review of cytology · doi:10.1016/bs.ircmb.2020.09.008 · Cited by 13

Autoimmune cytopenias associated with autoantibodies to nuclear envelope polypeptides

Coppo, P., Clauvel, J., Bengoufa, D., Fuentès, V., Gouilleux‐Gruart, V., Courvalin, J., & Lassoued, K. (2004) · American Journal of Hematology · doi:10.1002/ajh.20188 · Cited by 13

Central Nervous System Diseases and Inflammation

Tenner, A. J., & Pisalyaput, K. (2007) · Springer eBooks · doi:10.1007/978-0-387-73894-9_8 · Cited by 14

GENES AND GENETICS OF MURINE LUPUS

Kono, D. H., Baccalà, R., & Theofilopoulos, A. N. (2004) · Elsevier eBooks · doi:10.1016/b9-78-012433-9/01950-0119 · Cited by 13

The modulation of macrophage activation by tyrosine phosphorylation

Tietzel, I. (2002) · Frontiers in bioscience · doi:10.2741/tietzel · Cited by 13

The C-Mer Gene Is Induced by Epstein-Barr Virus Immediate-Early Protein BRLF1

Li, Y., Mahajan, N. P., Webster-Cyriaque, J. Y., Bhende, P. M., Hong, G. K., Earp, H. S., & Kenney, S. C. (2004) · Journal of Virology · doi:10.1128/jvi.78.21.11778-11785.2004 · Cited by 13

Efferocytosis in Health and Disease

Li, C., Yang, Y., Zhou, F., Jiang, Q., Jiang, Y., Huang, X., Zhang, Y., Ye, Z., Xu, G. X., Kao, G., et al. (2025) · MedComm · doi:10.1002/mco2.70546 · Cited by 15

Gas6 and Protein S Ligands Cooperate to Regulate MerTK Rhythmic Activity Required for Circadian Retinal Phagocytosis

Parinot, C., Chatagnon, J., Rieu, Q., Roux, S., Néel, D., Hamieh, A., & Nandrot, E. F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126630 · Cited by 12

Role of transcription factors in apoptotic cells clearance

Gao, Y.-Q., Jiao, Y., Gong, X., Liu, J., Xiao, H., & Zheng, Q. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1110225 · Cited by 12

Genetic polymorphism of the growth arrest-specific 6 gene is associated with cutaneous vasculitis in Taiwanese patients with systemic lupus erythematosus

Wu, C., Hu, C., Chan, C.-J., Chang, S., & Hsu, P. (2012) · Clinical Rheumatology · doi:10.1007/s10067-012-2027-z · Cited by 12

Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy

Llópiz, D., Ruiz, M., Silva, L., Repáraz, D., Aparicio, B., Egea, J., Lasarte, J. J., Redín, E., Calvo, A., Angel, M., et al. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.11.022 · Cited by 12

Cellular Nrf2 Levels Determine Cell Fate during Chemical Carcinogenesis in Esophageal Epithelium

Horiuchi, M., Taguchi, K., Hirose, W., Tsuchida, K., Suzuki, M., Taniyama, Y., Kamei, T., & Yamamoto, M. P. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00536-20 · Cited by 12

Functional specialization of short-lived and long-lived macrophage subsets in human tonsils

Alaoui, L., Villar, J., Leclère, R., Gallou, S. L., Relouzat, F., Michaud, H., Tarte, K., Teissier, N., Favier, B., Roussel, M., et al. (2023) · The Journal of Experimental Medicine · doi:10.1084/jem.20230002 · Cited by 11

Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle

Nasir, N. J. M., Heemskerk, H., Jenkins, J., Hamadee, N. H., Bunte, R. M., & Tucker‐Kellogg, L. (2023) · eLife · doi:10.7554/elife.85633 · Cited by 11

Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T‐cell responses

Valente, M., Baey, C., Louche, P., Dutertre, C., Vimeux, L., Marañón, C., Hosmalin, A., & Feuillet, V. (2014) · European Journal of Immunology · doi:10.1002/eji.201344191 · Cited by 12

Microglia at the Centre of Brain Research: Accomplishments and Challenges for the Future

Soares, N. L., & Vieira, H. L. A. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03456-1 · Cited by 14

Autoantibodies that bind glomeruli: Cross‐reactivity with bacterial antigen

Chowdhry, I. A., Kowal, C., Hardin, J., Zhou, Z., & Diamond, B. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21143 · Cited by 12

Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Behçet’s disease

Qin, J., Li, L., Zhang, D., Yu, H., Tan, H., Zhang, J., Deng, B., Kijlstra, A., & Yang, P. (2016) · Scientific Reports · doi:10.1038/srep26662 · Cited by 12

Potential Oncogenic Effect of the MERTK-Dependent Apoptotic-Cell Clearance Pathway in Starry-Sky B-Cell Lymphoma

Farnworth, S. L., Barth, N. D., Melville, L. A., Paterson, M., Lynch, C., Holland, P. J., Dransfield, I., & Gregory, C. D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01759 · Cited by 12

Cell death, autoantigen cleavage, and autoimmunity

Pollard, K. M. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10415 · Cited by 12

SOCS1 regulates a subset of NFκB-target genes through direct chromatin binding and defines macrophage functional phenotypes

Coelho, D. R., Palma, F. R., Paviani, V., LaFond, K. M., Huang, Y., Wang, D., Wray, B. D., Rao, S., Yue, F., Bonini, M. G., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106442 · Cited by 11

Tyro3 Promotes the Maturation of Glutamatergic Synapses

Miao, S., Fourgeaud, L., Burrola, P., Stern, S., Zhang, Y., Happonen, K. E., Novak, S. W., Gage, F. H., & Lemke, G. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1327423 · Cited by 12

MerTK negatively regulates Staphylococcus aureus induced inflammatory response via SOCS1/SOCS3 and Mal

Zahoor, A., Yang, C., Yang, Y., Akhtar, M. F., Umar, T., Khan, M. A., Ahmad, S., Deng, G., & Guo, M. (2020) · Immunobiology · doi:10.1016/j.imbio.2020.151960 · Cited by 11

Remodeling the Tumor Myeloid Landscape to Enhance Antitumor Antibody Immunotherapies

Hussain, K., Cragg, M. S., & Beers, S. A. (2021) · Cancers · doi:10.3390/cancers13194904 · Cited by 11

Triamcinolone regulated apopto-phagocytic gene expression patterns in the clearance of dying retinal pigment epithelial cells. A key role of Mertk in the enhanced phagocytosis

Albert, R., Kristóf, E., Zahuczky, G., Szatmári-Tóth, M., Veréb, Z., Oláh, B., Moe, M. C., Facskó, A., Fésüs, L., & Petrovski, G. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.10.026 · Cited by 11

Rab GTPases in the differential processing of phagocytosed pathogens versus efferocytosed apoptotic cells.

Taefehshokr, N., Yin, C., & Heit, B. (2021) · PubMed · doi:10.14670/hh-18-252 · Cited by 12

Experimental Use of Mouse Models of Systemic Lupus Erythematosus

Peng, S. L. (2012) · Methods in molecular biology · doi:10.1007/978-1-60761-720-4_7 · Cited by 12

Basic Science for the Clinician 42

Sigal, L. H. (2007) · JCR Journal of Clinical Rheumatology · doi:10.1097/01.rhu.0000256288.09733.22 · Cited by 11

Structural, Quantitative and Functional Comparison of Amyloid P Component in Sera from Patients with Systemic Lupus Erythematosus and Healthy Donors

Sen, J. W., Recke, C., Rahbek, L., Skogstrand, K., & Heegaard, N. (2002) · Scandinavian Journal of Immunology · doi:10.1046/j.1365-3083.2002.01178.x · Cited by 12

Increased Expression of MERTK is Associated with a Unique Form of Canine Retinopathy

Ahonen, S., Arumilli, M., Seppälä, E. H., Hakosalo, O., Kaukonen, M. K., Komáromy, A. M., & Lohi, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0114552 · Cited by 11

Apoptotic cells, autoantibodies, and the role of HMGB1 in the subcellular localization of an autoantigen

Sanford, A. N., Dietzmann, K., & Sullivan, K. E. (2005) · Journal of Autoimmunity · doi:10.1016/j.jaut.2005.08.005 · Cited by 11

ORIGINS OF ANTINUCLEAR ANTIBODIES

Reeves, W. H., Satoh, M., & Richards, H. B. (2004) · Elsevier eBooks · doi:10.1016/b978-012433901-9/50018-1 · Cited by 13

Defective clearance of nucleosomes and systemic lupus erythematosus

Maekawa, Y., & Yasutomo, K. (2001) · Trends in Immunology · doi:10.1016/s1471-4906(01)02084-1 · Cited by 11

GAS6/TAM Axis as Therapeutic Target in Liver Diseases

Tutusaus, A., Morales, A., de Frutos, P. G., & Marı́, M. (2024) · Seminars in Liver Disease · doi:10.1055/a-2275-0408 · Cited by 10

ICAM1+ gingival fibroblasts modulate periodontal inflammation to mitigate bone loss

Kim, W., Prasongyuenyong, K., Ko, A., Debnath, R., Chen, Z., Zhou, J. X., Shaaf, E., & Ko, K. I. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1484483 · Cited by 10

MERTK inhibition improves therapeutic efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

Llópiz, D., Silva, L., Ruiz, M., Castro-Alejos, C., Aparicio, B., Vegas, L., Infante, S., Santamaría, E., & Sarobe, P. (2025) · OncoImmunology · doi:10.1080/2162402x.2025.2473165 · Cited by 12

MerTK Does Not Mediate Phagocytosis of Staphylococcus aureus but Attenuates Inflammation Induced by Staphylococcal Lipoteichoic Acid Through Blocking NF-κB Activation

Zhang, B., Wu, H., Fang, L., Ding, P., Xu, K., Yang, Q., & Liu, R. (2017) · Inflammation · doi:10.1007/s10753-017-0595-4 · Cited by 10

Whole-Exome Sequencing Identified a TBX6 Loss of Function Mutation in a Patient with Distal Vaginal Atresia

Chu, C., Li, L., Lü, D., Duan, A., Luo, L., Li, S., & Yin, C. (2019) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2019.06.006 · Cited by 10

Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia

Bousset, L., Septier, A., Buñay, J., Voisin, A., Guiton, R., Damon‐Soubeyrand, C., Renaud, Y., Haze, A. D., Sapin, V., Fogli, A., et al. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000948 · Cited by 12

Molecular mechanisms insulating proliferation from genotoxic stress in B lymphocytes

Wright, N., Mandal, M., & Clark, M. R. (2023) · Trends in Immunology · doi:10.1016/j.it.2023.06.010 · Cited by 10

Tyro3 receptor tyrosine kinases in the heterogeneity of apoptotic cell uptake

Jeffrey, L. C. (2009) · Frontiers in bioscience · doi:10.2741/3401 · Cited by 10

Role of TLR2 in the pathogenesis of autoimmune diabetes and its therapeutic implication

Lee, M., Kim, D., Lee, J., Kim, S., & Kim, H. S. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1231 · Cited by 10

Environmental Factors Affecting Phagocytosis of Dying Cells:Smoking and Static Magnetic Fields

Dini, L., & Vergallo, C. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9293-0_15 · Cited by 10

Opposite Roles of MerTK Ligands Gas6 and Protein S During Retinal Phagocytosis

Nandrot, E. F. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-75402-4_70 · Cited by 11

Tampering with the Immune System

Schwartzberg, P. L. (2001) · Science · doi:10.1126/science.1063291 · Cited by 10

Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders

Sahara, N., & Higuchi, M. (2023) · FEBS Open Bio · doi:10.1002/2211-5463.13711 · Cited by 9

The Role of TAM Receptors in Bone

Engelmann, J., Ragipoglu, D., Batalla, I. B., & Loges, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010233 · Cited by 9

Novel Compound MMV1804559 from the Global Health Priority Box Exhibits In Vitro and In Vivo Activity against Madurella mycetomatis

Ma, J., Eadie, K., Schippers, M., Fahal, A. H., Laleu, B., Verbon, A., & van de Sande, W. W. J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116227 · Cited by 9

MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming

Zewdie, E. Y., Edwards, G. M., Hunter, D. M., Earp, H. S., & Holtzhausen, A. (2024) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-23-0666 · Cited by 9

Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment

Guo, J., He, J., Xu, S., Chen, X., Zhu, Z., Ji, X., & Wu, D. (2024) · Biomolecules · doi:10.3390/biom14101293 · Cited by 9

Immune checkpoint inhibitor induces cardiac injury by impairing efferocytosis of macrophages via MerTK cleavage

Zhang, Y., Cao, Z., Jia, H., Feng, Y., Sun, X., Wu, H., Xu, B., & Wei, Z. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114263 · Cited by 9

Plasma extracellular vesicle surface-located GAS6/PROS1 and CD39/CD73 attenuate inflammation

Fabiano, M. P., Adamczyk, A. M., Gololobova, O. A., Mazzitelli, I. G., Leicaj, M. L., Grosso, T. M., Pérez, P. S., Alvarez, C. L., Schachter, J., Palmer, S., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116096 · Cited by 12

A flexible high content imaging assay for profiling macrophage efferocytosis

Clark, R., Usselmann, L. E. J., Brown, M. R., Goeppert, A. U., & Corrigan, A. M. (2019) · Journal of Immunological Methods · doi:10.1016/j.jim.2019.112636 · Cited by 9

Cabozantinib Is Effective in Melanoma Brain Metastasis Cell Lines and Affects Key Signaling Pathways

Mannsåker, T. A., Hoang, T., Aasen, S. N., Bjørnstad, O. V., Parajuli, H., Sundstrøm, T., & Thorsen, F. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212296 · Cited by 9

Structure and functions of Mer, an innate immune checkpoint

Ubil, E., & Zahid, K. R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1244170 · Cited by 9

Macrophages in necrotic liver lesion repair: opportunities for therapeutical applications

Wang, Y., Rodrigues, R. M., Chen, C., Feng, D., Maccioni, L., & Gao, B. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00053.2024 · Cited by 10

Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers

Schell, S. L., Soni, C., Fasnacht, M. J., Domeier, P. P., Cooper, T. K., & Rahman, Z. S. M. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700611 · Cited by 9

Photoreceptor—RPE Interactions

Finnemann, S. C., & Chang, Y. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-374-5_4 · Cited by 9

Plasma Levels of Cell-Free Apoptotic DNA Ladders and Gamma-Glutamyltranspeptidase (GGT) in Diabetic Children

Langford, M. P., Redens, T. B., Harris, N. R., Lee, S., Jain, S. K., Reddy, S., & McVie, R. (2007) · Experimental Biology and Medicine · doi:10.3181/0701-rm-13 · Cited by 9

Recognition of apoptotic cells by viable cells is specific, ubiquitous, and species independent: analysis using photonic crystal biosensors

Pattabiraman, G., Lidstone, E. A., Palasiewicz, K., Cunningham, B. T., & Ucker, D. S. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-11-0700 · Cited by 9

Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage

Chen, C., Wu, Y.-Y., Lin, C., Kuo, C.-F., Han, C., Wang, S., Chuang, W., Chen, C.-Y., Wu, J.-J., Tsai, P.-J., et al. (2016) · Scientific Reports · doi:10.1038/srep26026 · Cited by 9

Adding Complexity to Phagocytic Signaling: Phagocytosis-Associated Cell Responses and Phagocytic Efficiency

García-García, E., & Rosales, C. (2006) · Springer eBooks · doi:10.1007/978-0-387-28669-3_5 · Cited by 9

A Common Pathway for All Autoimmune Diseases? The Unholy Alliance of Environment, Cell Death and Nucleic Acids

Hoffmann, M. H., & Steiner, G. E. (2009) · Current Immunology Reviews · doi:10.2174/157339509787314387 · Cited by 9

Role of Attraction and Danger Signals in the Uptake of Apoptotic and Necrotic Cells and its Immunological Outcome

Peter, C., Wesselborg, S., & Lauber, K. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9293-0_3 · Cited by 9

CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus

Chavula, T., To, S., Smith, J., Pedroza, M., Nimri, J., Devaraj, S., Wenderfer, S. E., Vogel, T. P., & Agarwal, S. K. (2024) · Journal of Autoimmunity · doi:10.1016/j.jaut.2024.103197 · Cited by 9

In the Eyes of the Beholder—New Mertk Knockout Mouse and Re-Evaluation of Phagocytosis versus Anti-Inflammatory Functions of MERTK

Ghosh, S., Finnemann, S. C., Vollrath, D., & Rothlin, C. V. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105299 · Cited by 8

Phosphatidylserine receptor and apoptosis: consequences of a non-ingested meal.

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A whodunit: an appointment with death

Giodini, A., & Albert, M. L. (2010) · Current Opinion in Immunology · doi:10.1016/j.coi.2010.01.023 · Cited by 8

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Kono, D. H., & Theofilopoulos, A. N. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-374994-9.10004-x · Cited by 8

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Cook, M. (2004) · Thrombosis Research · doi:10.1016/j.thromres.2004.06.037 · Cited by 8

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Gat, L. L., Gogat, K., Berghe, L. V. D., Brizard, M., Kobetz, A., Marchant, D., Abitbol, M. M., & Ménasche, M. (2003) · Cell Communication & Adhesion · doi:10.1080/714040418 · Cited by 8

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