The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Extending the lifespan of long-lived mice
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“There is overwhelming evidence that single gene mutations in nutrient-sensing pathways, such as insulin/insulin-like growth factor (IGF) signaling (Bartke et al., 2001) or the mechanistic target of rapamycin (mTOR) signaling pathways, extend lifespan and health span in invertebrates.”
From Metformin as a tool to target aging (2016) · cites this paper as Bartke et al., 2001
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“The lifespan and healthspan of invertebrates are extended by mutations in pathways such as the DAF-2, a gene that encodes for the IGF-1 pathway in the nematode Caenorhabditis elegans (C. elegans), or the mTOR signaling pathways that are linked to accelerating the aging process (60, 62–65).”
From A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan (2021) · cites this paper as [63]
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Cites
Kimura, K. D., Tissenbaum, H. A., Liu, Y., & Ruvkun, G. (1997) · Science · doi:10.1126/science.277.5328.942 · Cited by 2,250
Tatar, M., Kopelman, A. H., Epstein, D., Tu, M., Yin, C. ‐., & Garofalo, R. S. (2001) · Science · doi:10.1126/science.1057987 · Cited by 1,630
Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein
Clancy, D. J., Gems, D., Harshman, L. G., Oldham, S., Stocker, H., Hafen, E., Leevers, S. J., & Partridge, L. (2001) · Science · doi:10.1126/science.1057991 · Cited by 1,436
Dwarf mice and the ageing process
Brown‐Borg, H. M., Borg, K. E., Meliska, C. J., & Bartke, A. (1996) · Nature · doi:10.1038/384033a0 · Cited by 1,091
Regulation of Longevity and Stress Resistance by Sch9 in Yeast
Fabrizio, P., Pozza, F., Pletcher, S. D., Gendron, C. M., & Longo, V. D. (2001) · Science · doi:10.1126/science.1059497 · Cited by 874
Flurkey, K., Papaconstantinou, J., Miller, R. A., & Harrison, D. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111158898 · Cited by 826
Assessment of Growth Parameters and Life Span of GHR/BP Gene-Disrupted Mice 1
Coschigano, K. T., Clemmons, D., Bellush, L. L., & Kopchick, J. J. (2000) · Endocrinology · doi:10.1210/endo.141.7.7586 · Cited by 611
The Retardation of Aging by Caloric Restriction: Studies in Rodents and Primates
Weindruch, R. H. (1996) · Toxicologic Pathology · doi:10.1177/019262339602400618 · Cited by 268
Delayed Aging in Ames Dwarf Mice. Relationships to Endocrine Function and Body Size
Bartke, A. (2000) · Results and problems in cell differentiation · doi:10.1007/978-3-540-48003-7_10 · Cited by 109
Harris, S. B., Gunion, M. W., Rosenthal, M. J., & Walford, R. L. (1994) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(94)90053-1 · Cited by 81
Research works printed but not linked: 1
- Mattison, J. A. et al. J. Am. Aging Assoc. 23, 9–16 (2000).
Cited by
Sorted by citations
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
Holzenberger, M., Dupont, J., Ducos, B., Leneuve, P., Géloën, A., Even, P. C., Cervera, P., & Le Bouc, Y. (2003) · Nature · doi:10.1038/nature01298 · Cited by 2,109
Ink4a/Arf expression is a biomarker of aging
Krishnamurthy, J., Torrice, C., Ramsey, M. R., Kovalev, G. I., Al-Regaiey, K., Su, L., & Sharpless, N. E. (2004) · Journal of Clinical Investigation · doi:10.1172/jci22475 · Cited by 1,486
The Endocrine Regulation of Aging by Insulin-like Signals
Tatar, M., Bartke, A., & Antebi, A. (2003) · Science · doi:10.1126/science.1081447 · Cited by 1,327
The plasticity of aging: insights from long-lived mutants
Kenyon, C. (2005) · Cell · doi:10.1016/j.cell.2005.02.002 · Cited by 1,338
Metformin as a tool to target aging
Barzilai, N., Crandall, J. P., Kritchevsky, S. B., & Espeland, M. A. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.05.011 · Cited by 1,096
Metadata
- Authors
- Bartke, A., Wright, J. C., Mattison, J. A., Ingram, D. K., Miller, R. A., & Roth, G. S.
- Affiliations
- Southern Illinois University Carbondale (US)
- National Institutes of Health (US)
- University of Michigan (US)
- Corresponding author
- Bartke, Andrzej
- Venue
- Nature
- Published
- 2001-11-22
- Volume
- 414
- Issue
- 6862
- Pages
- 412-412
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1994357518
- Cited by
- 422
- References
- 11
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 12 · 2023: 10 · 2022: 5 · 2021: 15 · 2020: 11 · 2019: 15 · 2018: 20 · 2017: 9 · 2016: 9 · 2015: 18 · 2014: 14 · 2013: 19 · 2012: 12
- FWCI
- 6.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Keywords
- Ames dwarf mice, lifespan extension, caloric restriction, PROP1, dietary restriction, aging mechanisms
- MeSH terms
- Animals, Energy Intake, Dwarfism, Female, Longevity, Male, Mice, Mutant Strains, Transcription Factors, Homeodomain Proteins, Mice
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