Ingram, Donald K.

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 4,290

Metformin improves healthspan and lifespan in mice

Martin-Montalvo, A., Mercken, E. M., Mitchell, S. J., Palacios, H. H., Mote, P. L., Scheibye-Knudsen, M., Gomes, A. P., Ward, T. M., Minor, R. K., Blouin, M.-J., et al. (2013) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 1,445

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

Pearson, K. J., Baur, J. A., Lewis, K. N., Peshkin, L., Price, N. L., Labinskyy, N., Swindell, W. R., Kamara, D., Minor, R. K., Perez, E., et al. (2008) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 1,162

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

Mattison, J. A., Roth, G. S., Beasley, T. M., Tilmont, E. M., Handy, A. M., Herbert, R. L., Longo, D. L., Allison, D. B., Young, J. E., Bryant, M., et al. (2012) · Nature

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 1,145

Caloric restriction improves health and survival of rhesus monkeys

Mattison, J. A., Colman, R. J., Beasley, T. M., Allison, D. B., Kemnitz, J. W., Roth, G. S., Ingram, D. K., Weindruch, R., de Cabo, R., & Anderson, R. M. (2017) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 838

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

López-Lluch, G., Hunt, N., Jones, B., Zhu, M., Jamieson, H., Hilmer, S., Cascajo, M. V., Allard, J., Ingram, D. K., Navas, P., et al. (2006) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 699

Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

Youm, Y.-H., Grant, R. W., McCabe, L. R., Albarado, D. C., Nguyen, K. Y., Ravussin, A., Pistell, P., Newman, S., Carter, R., Laque, A., et al. (2013) · Cell Metabolism

Inflammasome and immune disordersGenetics, Aging, and Longevity in Model Organisms

Cited by 674

Interventions to slow aging in humans: are we ready?

Longo, V. D., Antebi, A., Bartke, A., Barzilai, N., Brown‐Borg, H. M., Caruso, C., Curiel, T. J., Cabo, R., Franceschi, C., Gems, D., et al. (2015) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 592

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., et al. (2016) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 451

AGEMAP: A Gene Expression Database for Aging in Mice

Zahn, J. M., Poosala, S., Owen, A. B., Ingram, D. K., Lustig, A., Carter, A., Weeraratna, A. T., Taub, D. D., Gorospe, M., Mazan-Mamczarz, K., et al. (2007) · PLoS Genetics

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 431

Extending the Lifespan of Long-Lived Mice

Bartke, A., Wright, J. C., Mattison, J. A., Ingram, D. K., Miller, R. A., & Roth, G. S. (2001) · Nature

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 422

A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults

Stote, K. S., Baer, D. J., Spears, K., Paul, D. R., Harris, G. K., Rumpler, W. V., Strycula, P., Najjar, S. S., Ferrucci, L., Ingram, D. K., et al. (2007) · The American Journal of Clinical Nutrition

Dietary Effects on HealthNutrition, Health and Food Behavior

Cited by 392

Dietary Restriction Benefits Learning and Motor Performance of Aged Mice

Ingram, D. K., Weindruch, R., Spangler, E. L., Freeman, J. R., & Walford, R. L. (1987) · Journal of Gerontology

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 342

Overexpression of dopamine D2 receptors reduces alcohol self‐administration

Thanos, P. K., Volkow, N. D., Freimuth, P., Umegaki, H., Ikari, H., Roth, G., Ingram, D. K., & Hitzemann, R. (2001) · Journal of Neurochemistry

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 324

Age and gender effects on microglia and astrocyte numbers in brains of mice

Mouton, P. R., Long, J. M., Lei, D.-L., Howard, V., Jucker, M., Calhoun, M. E., & Ingram, D. K. (2002) · Brain Research

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 320

Dietary deprivation extends lifespan in Caenorhabditis elegans

Lee, G. D., Wilson, M. A., Zhu, M., Wolkow, C. A., De Cabo, R., Ingram, D. K., & Zou, S. (2006) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 307

Effects of intermittent feeding upon body weight and lifespan in inbred mice: interaction of genotype and age

Goodrick, C. L., Ingram, D. K., Reynolds, M. A., Freeman, J. R., & Cider, N. (1990) · Mechanisms of Ageing and Development

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 279

Nutrition, Brain Aging, and Neurodegeneration: Table 1.

Joseph, J., Cole, G., Head, E., & Ingram, D. (2009) · The Journal of Neuroscience

Dementia and Cognitive Impairment ResearchNutritional Studies and Diet

Cited by 264

Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet

White, C. L., Pistell, P. J., Purpera, M. N., Gupta, S., Fernandez-Kim, S.-O., Hise, T. L., Keller, J. N., Ingram, D. K., Morrison, C. D., & Bruce-Keller, A. J. (2009) · Neurobiology of Disease

Birth, Development, and HealthFatty Acid Research and Health

Cited by 245

Stereological analysis of astrocyte and microglia in aging mouse hippocampus

Long, J. M., Kalehua, A. N., Muth, N. J., Calhoun, M. E., Jucker, M., Hengemihle, J. M., Ingram, D. K., & Mouton, P. R. (1998) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 163

Metformin Supplementation and Life Span in Fischer-344 Rats

Smith, D. L., Elam, C. F., Mattison, J. A., Lane, M. A., Roth, G. S., Ingram, D. K., & Allison, D. B. (2010) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 153

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

Thanos, P. K., Taintor, N. B., Rivera, S. N., Umegaki, H., Ikari, H., Roth, G., Ingram, D. K., Hitzemann, R., Fowler, J. S., Gatley, S. J., et al. (2004) · Alcoholism Clinical and Experimental Research

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 125

Measures of Healthspan as Indices of Aging in Mice—A Recommendation

Richardson, A., Fischer, K. E., Speakman, J. R., de Cabo, R., Mitchell, S. J., Peterson, C. A., Rabinovitch, P., Chiao, Y. A., Taffet, G., Miller, R. A., et al. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 81

Optimal window of caloric restriction onset limits its beneficial impact on T‐cell senescence in primates

Messaoudi, I., Fischer, M., Warner, J., Park, B., Mattison, J., Ingram, D. K., Totonchy, T., Mori, M., & Nikolich‐Žugich, J. (2008) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 57