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Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

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SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

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The metabolic regulation of aging

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Autophagy as a therapeutic target in cancer

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Dietary Restriction in Long-Lived Dwarf Flies

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Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

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A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan

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Minireview: The Role of Oxidative Stress in Relation to Caloric Restriction and Longevity

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Age to survive: DNA damage and aging

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Oxidative Stress and Autophagy in Cardiac Disease, Neurological Disorders, Aging and Cancer

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Long-Lived Growth Hormone Receptor Knockout Mice: Interaction of Reduced Insulin-Like Growth Factor I/Insulin Signaling and Caloric Restriction

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Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster : not required, but its activity modulates the response

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Remarkable longevity and stress resistance of nematode PI3K‐null mutants

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Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

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The Size–Life Span Trade-Off Decomposed: Why Large Dogs Die Young

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Growth Hormone Deficiency: Health and Longevity

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Aging, Atherosclerosis, and IGF-1

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Drosophila lifespan control by dietary restriction independent of insulin‐like signaling

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Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

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It is time to classify biological aging as a disease

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A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan

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Identification of potential caloric restriction mimetics by microarray profiling

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An investigation into the relationship between age and physiological function in highly active older adults

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The Role of Insulin-like Growth Factor-1 (IGF-1) in the Control of Neuroendocrine Regulation of Growth

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Calorie restriction and SIR2 genes—Towards a mechanism

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Isolated Growth Hormone Deficiency (GHD) in Childhood and Adolescence: Recent Advances

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Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice

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Subfield History: Caloric Restriction, Slowing Aging, and Extending Life

Masoro, E. J. (2003) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2003.8.re2 · Cited by 149

Calorie Restriction and Dietary Restriction Mimetics: A Strategy for Improving Healthy Aging and Longevity

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Additive regulation of hepatic gene expression by dwarfism and caloric restriction

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Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice

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Regulation of longevity and oxidative stress by nutritional interventions: Role of methionine restriction

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Regulation of GH and GH Signaling by Nutrients

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Royal Jelly prolongs the life span of C3H/HeJ mice: correlation with reduced DNA damage

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Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice

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Is height related to longevity?

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Reactive Metabolites and AGE/RAGE-Mediated Cellular Dysfunction Affect the Aging Process – A Mini-Review

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Growth Hormone and Aging: Updated Review

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Two-Year Body Composition Analyses of Long-Lived GHR Null Mice

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Gene expression profile of long‐lived Ames dwarf mice and Little mice

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Canagliflozin extends life span in genetically heterogeneous male but not female mice

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Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin

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Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction

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What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

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Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity

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Caloric restriction-induced life extension of rats and mice: A critique of proposed mechanisms

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Gene Expression Patterns in Calorically Restricted Mice: Partial Overlap with Long-Lived Mutant Mice

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Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice

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Biochemical Genetic Pathways that Modulate Aging in Multiple Species: Figure 1.Preprint

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Life history response of Mediterranean fruit flies to dietary restriction

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SIRT 1 but not its increased expression is essential for lifespan extension in caloric‐restricted mice

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Metabolic effects of intra‐abdominal fat in GHRKO mice

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