Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor

Inositol trisphosphate and calcium signalling

Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545

The Cerebellum as a Neuronal Machine

Eccles, J. C., Ito, M., & Szentágothai, J. (1967) · Springer eBooks · doi:10.1007/978-3-662-13147-3 · Cited by 3,229

Genetic variants and strains of the laboratory mouse

(1990) · Choice Reviews Online · doi:10.5860/choice.28-1324 · Cited by 1,492

Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices.

Llinas, R. H., & Sugimori, M. (1980) · The Journal of Physiology · doi:10.1113/jphysiol.1980.sp013357 · Cited by 1,061

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

Furuichi, T., Yoshikawa, S., Miyawaki, A., Wada, K., Maeda, N., & Mikoshiba, K. (1989) · Nature · doi:10.1038/342032a0 · Cited by 1,041

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

Aiba, A., Kano, M., Chen, C., Stanton, M. E., Fox, G. D., Herrup, K., Zwingman, T. A., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90205-4 · Cited by 930

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

Aiba, A. (1994) · Cell · doi:10.1016/0092-8674(94)90204-6 · Cited by 614

Synaptic‐ and agonist‐induced excitatory currents of Purkinje cells in rat cerebellar slices.

Llano, I., Marty, A., Armstrong, C. M., & Konnerth, A. (1991) · The Journal of Physiology · doi:10.1113/jphysiol.1991.sp018465 · Cited by 488

Synaptic currents in cerebellar Purkinje cells.

Konnerth, A., Llano, I., & Armstrong, C. M. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.7.2662 · Cited by 424

Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene

Takeshima, H., lino, M., Takekura, H., Nishi, M., Kuno, J., Minowa, O., Takano, H., & Noda, T. (1994) · Nature · doi:10.1038/369556a0 · Cited by 390

The Cytoprotective Effects of Dantrolene

Inan, S., & Wei, H. (2010) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181f7181c · Cited by 86

Clinical Neurogenetics

Shakkottai, V. G., & Fogel, B. L. (2013) · Neurologic Clinics · doi:10.1016/j.ncl.2013.04.006 · Cited by 81

The Synaptic Targeting of mGluR1 by Its Carboxyl-Terminal Domain Is Crucial for Cerebellar Function

Ohtani, Y., Miyata, M., Hashimoto, K., Tabata, T., Kishimoto, Y., Fukaya, M., Kase, D., Kassai, H., Nakao, K., Hirata, T., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3542-13.2014 · Cited by 84

Lateral Diffusion of Inositol 1,4,5-Trisphosphate Receptor Type 1 Is Regulated by Actin Filaments and 4.1N in Neuronal Dendrites

Fukatsu, K., Bannai, H., Zhang, S., Nakamura, H., Inoue, T., & Mikoshiba, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408364200 · Cited by 82

Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

Uchida, K., Aramaki, M., Nakazawa, M., Yamagishi, C., Makino, S., Fukuda, K., Nakamura, T., Takahashi, T., Mikoshiba, K., & Yamagishi, H. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012500 · Cited by 78

Forebrain-Specific Inactivation of G q /G 11 Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation

Wettschureck, N., van der Stelt, M., Tsubokawa, H., Krestel, H. E., Moers, A., Petrosino, S., Schütz, G., Marzo, V. D., & Offermanns, S. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00397-06 · Cited by 76

Cellular and circuit mechanisms underlying spinocerebellar ataxias

Meera, P., Pulst, S. M., & Otis, T. S. (2016) · The Journal of Physiology · doi:10.1113/jp271897 · Cited by 83

Inositol 1,4,5‐trisphosphate receptors and neurodegenerative disorders

Egorova, P. A., & Борисович, Б. И. (2017) · FEBS Journal · doi:10.1111/febs.14366 · Cited by 82

STIM1/ORAI1 Loss-of-Function and Gain-of-Function Mutations Inversely Impact on SOCE and Calcium Homeostasis and Cause Multi-Systemic Mirror Diseases

Silva‐Rojas, R., Laporte, J., & Böhm, J. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.604941 · Cited by 78

The use of transgenic mouse models to reveal the functions of Ca2+ buffer proteins in excitable cells

Schwaller, B. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.11.008 · Cited by 75

Abolished InsP3R2 function inhibits sweat secretion in both humans and mice

Klar, J., Hisatsune, C., Baig, S. M., Tariq, M., Johansson, A., Rasool, M., Malik, N. A., Ameur, A., Sugiura, K., Feuk, L., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci70720 · Cited by 75

Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver

Feriod, C. N., de Oliveira, A. G., Guerra, M. T., Nguyen, L. L., Richards, K. M., Jurczak, M. J., Ruan, H., Camporez, J. P., Yang, X., Shulman, G. I., et al. (2016) · Hepatology Communications · doi:10.1002/hep4.1012 · Cited by 80

The genetic architecture of aniridia and Gillespie syndrome

Hall, H. N., Williamson, K. A., & FitzPatrick, D. R. (2018) · Human Genetics · doi:10.1007/s00439-018-1934-8 · Cited by 75

Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics

Guo, D., Yang, X., & Shi, L. (2020) · Cells · doi:10.3390/cells9040835 · Cited by 73

Loss of Flight and Associated Neuronal Rhythmicity in Inositol 1,4,5-Trisphosphate Receptor Mutants ofDrosophila

Banerjee, S., Lee, J., Venkatesh, K., Wu, C., & Hasan, G. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0656-04.2004 · Cited by 73

IP3 receptors regulate vascular smooth muscle contractility and hypertension

Lin, Q., Zhao, G., Fang, X., Peng, X., Tang, H., Wang, H., Jing, R., Liu, J., Lederer, W. J., Chen, J., et al. (2016) · JCI Insight · doi:10.1172/jci.insight.89402 · Cited by 73

SCA15 Due to Large ITPR1 Deletions in a Cohort of 333 White Families With Dominant Ataxia

Marelli, C., van de Leemput, J., Johnson, J. O., Tison, F., Thauvin‐Robinet, C., Picard, F., Tranchant, C., Hernandez, D. G., Huttin, B., Boulliat, J., et al. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.81 · Cited by 72

Aberrant IP 3 receptor activities revealed by comprehensive analysis of pathological mutations causing spinocerebellar ataxia 29

Ando, H., Hirose, M., & Mikoshiba, K. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1811129115 · Cited by 74

The Friedreich's ataxia gene encodes a novel phosphatidylinositol–4–phosphate 5–kinase

Carvajal, J. J., Pook, M. A., dos Santos, M., Doudney, K., Hillermann, R., Minogue, S., Williamson, R., Hsuan, J. J., & Chamberlain, S. (1996) · Nature Genetics · doi:10.1038/ng1096-157 · Cited by 72

Ion channel dysfunction in cerebellar ataxia

Bushart, D. D., & Shakkottai, V. G. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.02.005 · Cited by 71

Intracellular Ca2+ release channels in evolution

Sorrentino, V., Barone, V., & Rossi, D. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00139-8 · Cited by 71

Spinocerebellar ataxia type 15 (sca15) maps to 3p24.2-3pter:

Knight, M. A., Kennerson, M. L., Anney, R., Matsuura, T., Nicholson, G. A., Salimi-Tari, P., Gardner, R. J. M., Storey, E., & Forrest, S. M. (2003) · Neurobiology of Disease · doi:10.1016/s0969-9961(03)00029-9 · Cited by 70

A Genome-Wide Significant Linkage for Severe Depression on Chromosome 3: The Depression Network Study

Breen, G. D., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N. J., Gill, M., Korszun, A., Maier, W., Middleton, L. T., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10091342 · Cited by 69

Functions of Class V Myosins in Neurons*

Hammer, J., & Wagner, W. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r113.514497 · Cited by 60

Regulated Disruption of Inositol 1,4,5-Trisphosphate Signaling inCaenorhabditis elegansReveals New Functions in Feeding and Embryogenesis

Walker, D. S., Gower, N. J. D., Ly, S., Bradley, G. L., & Baylis, H. A. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-08-0422 · Cited by 67

Calcium channelopathies in the central nervous system

Jen, J. C. (1999) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)80040-3 · Cited by 67

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia

Ouyang, K., Gomez-Amaro, R. L., Stachura, D. L., Tang, H., Peng, X., Fang, X., Traver, D. J., Evans, S. Μ., & Chen, J. (2014) · Nature Communications · doi:10.1038/ncomms5814 · Cited by 65

Ryanodine receptor calcium release channels: lessons from structure–function studies

Amador, F. J., Stathopulos, P. B., Enomoto, M., & Ikura, M. (2013) · FEBS Journal · doi:10.1111/febs.12194 · Cited by 66

Motor discoordination in mutant mice heterozygous for the type 1 inositol 1,4,5-trisphosphate receptor

Ogura, H., Matsumoto, M., & Mikoshiba, K. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00187-5 · Cited by 65

Phosphorylation of Homer3 by Calcium/Calmodulin-Dependent Kinase II Regulates a Coupling State of Its Target Molecules in Purkinje Cells

Mizutani, A., Kuroda, Y., Futatsugi, A., Furuichi, T., & Mikoshiba, K. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4738-07.2008 · Cited by 65

Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias

Tada, M., Nishizawa, M., & Onodera, O. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.01.007 · Cited by 64

Cellular Mechanisms of Myogenic Activity in Gastric Smooth Muscle.

Suzuki, H. (2000) · The Japanese Journal of Physiology · doi:10.2170/jjphysiol.50.289 · Cited by 64

IP 3 receptor mutations and brain diseases in human and rodents

Hisatsune, C., & Mikoshiba, K. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.13991 · Cited by 62

NCS-1 is a regulator of calcium signaling in health and disease

Boeckel, G. R., & Ehrlich, B. E. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2018.05.005 · Cited by 63

Astrocytic IP3Rs: Beyond IP3R2

Sherwood, M. W., Arizono, M., Panatier, A., Mikoshiba, K., & Oliet, S. H. R. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.695817 · Cited by 65

Glutamate Receptor δ2 Associates with Metabotropic Glutamate Receptor 1 (mGluR1), Protein Kinase Cγ, and Canonical Transient Receptor Potential 3 and Regulates mGluR1-Mediated Synaptic Transmission in Cerebellar Purkinje Neurons

Kato, A., Knierman, M. D., Siuda, E. R., Isaac, J. T. R., Nisenbaum, E. S., & Bredt, D. S. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0705-12.2012 · Cited by 68

Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia

Jarius, S., Scharf, M., Begemann, N., STÖCKER, W., Probst, C., Serysheva, I. I., Nagel, S., Graus, F., Psimaras, D., Wildemann, B., et al. (2014) · Journal of Neuroinflammation · doi:10.1186/s12974-014-0206-3 · Cited by 62

Cardiac arrhythmia and neuroexcitability gene variants in resected brain tissue from patients with sudden unexpected death in epilepsy (SUDEP)

Friedman, D. J., Kannan, K. S., Faustin, A., Shroff, S., Thomas, C., Heguy, A., Serrano, J., Snuderl, M., & Devinsky, O. (2018) · npj Genomic Medicine · doi:10.1038/s41525-018-0048-5 · Cited by 65

Aberrant Cerebellar Circuitry in the Spinocerebellar Ataxias

Robinson, K. J., Watchon, M., & Laird, A. S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00707 · Cited by 59

Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer's disease

Egorova, P. A., Александровна, П. Е., & Борисович, Б. И. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.03.010 · Cited by 60

Excitation–Contraction Coupling of the Mouse Embryonic Cardiomyocyte

Rapila, R., Korhonen, T., & Tavi, P. (2008) · The Journal of General Physiology · doi:10.1085/jgp.200809960 · Cited by 60

IP3 Receptor Plasticity Underlying Diverse Functions

Hamada, K., & Mikoshiba, K. (2019) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034433 · Cited by 59

ROR Regulates Multiple Aspects of Dendrite Development in Cerebellar Purkinje Cells In Vivo

Takeo, Y. H., Kakegawa, W., Miura, E., & Yuzaki, M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0075-15.2015 · Cited by 58

InsP3 receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

Lür, G., Sherwood, M. W., Ebisui, E., Haynes, L. P., Feske, S., Sutton, R., Burgoyne, R. D., Mikoshiba, K., Petersen, O. H., & Tepikin, A. V. (2011) · Biochemical Journal · doi:10.1042/bj20110083 · Cited by 59

Tyr-167/Trp-168 in Type 1/3 Inositol 1,4,5-Trisphosphate Receptor Mediates Functional Coupling between Ligand Binding and Channel Opening

Yamazaki, H., Chan, J., Ikura, M., Michikawa, T., & Mikoshiba, K. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.140129 · Cited by 59

IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice

Hisatsune, C., Miyamoto, H., Hirono, M., Yamaguchi, N., Sugawara, T., Ogawa, N., Ebisui, E., Ohshima, T., Yamada, M., Hensch, T. K., et al. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00156 · Cited by 59

Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells

Zhao, G., Neeb, Z. P., Leo, M. D., Pachuau, J., Adebiyi, A., Ouyang, K., Chen, J., & Jaggar, J. H. (2010) · The Journal of General Physiology · doi:10.1085/jgp.201010453 · Cited by 59

Large conductance calcium-activated potassium channels affect both spontaneous firing and intracellular calcium concentration in cerebellar Purkinje neurons

Womack, M. D., Hoang, C. V., & Khodakhah, K. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.05.016 · Cited by 58

Seizure disorders in mutant mice: Relevance to human epilepsies

Puranam, R. S., & McNamara, J. O. (1999) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)80041-5 · Cited by 58

Genetic Dissection of itpr Gene Function Reveals a Vital Requirement in Aminergic Cells of Drosophila Larvae

Joshi, R., Venkatesh, K., Srinivas, R., Nair, S. S., & Hasan, G. (2004) · Genetics · doi:10.1534/genetics.166.1.225 · Cited by 56

Effects of zonisamide on neurotransmitter exocytosis associated with ryanodine receptors

Yoshida, S., Okada, M., Zhu, G., & Kaneko, S. (2005) · Epilepsy Research · doi:10.1016/j.eplepsyres.2005.10.001 · Cited by 55

Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice

Matsumoto, M., & Nagata, E. (1999) · Journal of Molecular Medicine · doi:10.1007/s001090050370 · Cited by 56

Involvement of IP3 receptors in LTP and LTD induction in guinea pig hippocampal CA1 neuronsPreprint

Taufiq, A. M., Fujii, S., Yamazaki, Y., Sasaki, H., Kaneko, K., Li, J., Kato, H., & Mikoshiba, K. (2005) · Learning & Memory · doi:10.1101/lm.17405 · Cited by 55

An ITPR1 gene deletion causes spinocerebellar ataxia 15/16: A genetic, clinical and radiological description

Novak, M. J. U., Sweeney, M. G., Li, A., Treacy, C., Hoskote, C., Giunti, P., Goold, R., Davis, M. B., Houlden, H., & Tabrizi, S. J. (2010) · Movement Disorders · doi:10.1002/mds.23223 · Cited by 55

Inositol 1,4,5-Trisphosphate Receptor Type 1 in Granule Cells, Not in Purkinje Cells, Regulates the Dendritic Morphology of Purkinje Cells through Brain-Derived Neurotrophic Factor Production

Hisatsune, C., Kuroda, Y., Akagi, T., Torashima, T., Hirai, H., Hashikawa, T., Inoue, T., & Mikoshiba, K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3269-06.2006 · Cited by 54

Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test

Galeotti, N., Bartolini, A., & Ghelardini, C. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.09.005 · Cited by 54

The disabled 1 gene is disrupted by a replacement with L1 fragment in yotari mice

Kojima, T., Nakajima, K., & Mikoshiba, K. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00313-7 · Cited by 55

Cardiac inositol 1,4,5-trisphosphate receptors

Garcia, M. I., & Boehning, D. F. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.11.017 · Cited by 53

Stroke Pattern Interpretation: The Variability of Hypertensive versus Amyloid Angiopathy Hemorrhage

Lang, E. W., Ya, Z. R., Preul, C., Hugo, H., Hempelmann, R. G., Buhl, R. M., Barth, H., Klinge, H., & Mehdorn, H. M. (2001) · Cerebrovascular Diseases · doi:10.1159/000047691 · Cited by 54

Ca 2+ transport and signalling in enamel cells

Nurbaeva, M. K., Eckstein, M., Feske, S., & Lacruz, R. S. (2016) · The Journal of Physiology · doi:10.1113/jp272775 · Cited by 53

Eyeblink conditioning, motor control, and the analysis of limbic-cerebellar interactions

Weiss, C., & Disterhoft, J. F. (1996) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00081929 · Cited by 54

Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development

Shimobayashi, E., & Kapfhammer, J. P. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170529104000 · Cited by 51

Association of the type 1 inositol (1,4,5)-trisphosphate receptor with 4.1N protein in neurons

Maximov, A., Tang, T.-S., & Борисович, Б. И. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(02)00027-1 · Cited by 51

Hydrogen peroxide increases GABAergic mIPSC through presynaptic release of calcium from IP3 receptor‐sensitive stores in spinal cord substantia gelatinosa neurons

Takahashi, A., Mikami, M., & Yang, J. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05323.x · Cited by 50

Crucial Role of Type 1, but Not Type 3, Inositol 1,4,5-Trisphosphate (IP 3 ) Receptors in IP 3 -Induced Ca 2+ Release, Capacitative Ca 2+ Entry, and Proliferation of A7r5 Vascular Smooth Muscle Cells

Wang, Y., Chen, J., Wang, Y., Taylor, C. W., Hirata, Y., Hagiwara, H., Mikoshiba, K., Toyo‐oka, T., Omata, M., & Sakaki, Y. (2001) · Circulation Research · doi:10.1161/01.res.88.2.202 · Cited by 50

Disruption of metabotropic glutamate receptor signalling is a major defect at cerebellar parallel fibre–Purkinje cell synapses in staggerer mutant mice

Mitsumura, K., Hosoi, N., Furuya, N., & Hirai, H. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.207563 · Cited by 48

Intracellular calcium channels: Inositol-1,4,5-trisphosphate receptors

Fedorenko, O. A., Александровна, П. Е., Enomoto, M., Stathopulos, P. B., Ikura, M., & Борисович, Б. И. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.10.074 · Cited by 48

Structural Studies of Inositol 1,4,5-Trisphosphate Receptor

Chan, J., Yamazaki, H., Ishiyama, N., Seo, M., Mal, T. K., Michikawa, T., Mikoshiba, K., & Ikura, M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.140160 · Cited by 48

Inositol Phosphates and Phosphoinositides in Health and Disease

Shi, Y. H., Azab, A. N., Thompson, M. N., & Greenberg, M. L. (2006) · Springer eBooks · doi:10.1007/0-387-27600-9_11 · Cited by 46

Recent Advances in the Genetics of Epilepsy: Insights from Human and Animal Studies

Prasad, A. N., Prasad, C., & Stafstrom, C. E. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb02004.x · Cited by 47

Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels

Katoh‐Semba, R., TAKEUCHI, I. K., Inaguma, Y., Ichisaka, S., Hata, Y., Tsumoto, T., Iwai, M., Mikoshiba, K., & Kato, K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.t01-1-00138.x · Cited by 47

Functional Characterization of the Type 1 Inositol 1,4,5-Trisphosphate Receptor Coupling Domain SII(±) Splice Variants and the Opisthotonos Mutant Form

Tu, H., Miyakawa, T., Wang, Z., Glouchankova, L., Iino, M., & Борисович, Б. И. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)75548-3 · Cited by 47

Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes

Ye, R., Ni, M., Wang, M., Luo, S. D., Zhu, G., Chow, R. H.-P., & Lee, A. S. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0012 · Cited by 46

A positive feedback loop linking enhanced mGluR function and basal calcium in spinocerebellar ataxia type 2

Meera, P., Pulst, S. M., & Otis, T. S. (2017) · eLife · doi:10.7554/elife.26377 · Cited by 46

Ataxia, arrhythmia and ion-channel gene defects

Doyle, J., & Stubbs, L. J. (1998) · Trends in Genetics · doi:10.1016/s0168-9525(97)01370-x · Cited by 46

The Moonwalker Mouse: New Insights into TRPC3 Function, Cerebellar Development, and Ataxia

Becker, E. B. E. (2014) · The Cerebellum · doi:10.1007/s12311-014-0564-5 · Cited by 45

Inositol 1,4,5-tripshosphate receptor, calcium signalling and huntington’s disease

Борисович, Б. И. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6191-2_11 · Cited by 45

Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP(3) type 1 receptor.

Nagase, T., Ito, K., Kato, K., Kaneko, K., Kohda, K., Matsumoto, M., Hoshino, A., Inoue, T., Fujii, S., Kato, H., et al. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00803-5 · Cited by 47

De novo ITPR1 variants are a recurrent cause of early-onset ataxia, acting via loss of channel function

Synofzik, M., Helbig, K. L., Harmuth, F., Deconinck, T., Tanpaiboon, P., Sun, B., Guo, W., Wang, R., Palmaer, E., Tang, S., et al. (2018) · European Journal of Human Genetics · doi:10.1038/s41431-018-0206-3 · Cited by 44

Toward a high-resolution structure of IP3R channel

Serysheva, I. I. (2014) · Cell Calcium · doi:10.1016/j.ceca.2014.08.002 · Cited by 43

Pathophysiological consequences of isoform-specific IP3 receptor mutations

Kerkhofs, M., Seitaj, B., Ivanova, H., Monaco, G., Bultynck, G., & Parys, J. B. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2018.06.004 · Cited by 43

High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsy

Conte, G., Parras, A., Alves, M., Ollà, I., de Diego-García, L., Beamer, E. H., Alalqam, R., Ocampo, A., Méndez, R., Henshall, D. C., et al. (2020) · Epilepsia · doi:10.1111/epi.16714 · Cited by 43

cGK Substrates

Schlossmann, J., & Desch, M. (2008) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-68964-5_9 · Cited by 43

Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβ

Sugawara, T., Hisatsune, C., Miyamoto, H., Ogawa, N., & Mikoshiba, K. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617270114 · Cited by 45

Cyst formation following disruption of intracellular calcium signaling

Kuo, I. Y., DesRochers, T. M., Kimmerling, E. P., Nguyen, L. L., Ehrlich, B. E., & Kaplan, D. L. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1412323111 · Cited by 41

Reevaluating the Role of Vascular Changes in the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia

Gold, G., Giannakopoulos, P., & Bouras, C. (1998) · European Neurology · doi:10.1159/000007968 · Cited by 40

Spinocerebellar ataxia in the Italian Spinone dog is associated with an intronic GAA repeat expansion in ITPR1

Forman, O. P., Risio, L. D., Matiasek, K., Platt, S. R., & Mellersh, C. S. (2014) · Mammalian Genome · doi:10.1007/s00335-014-9547-6 · Cited by 40

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle

Wang, Q., Yue, W. W. S., Jiang, Z., Xue, T., Kang, S. H., Bergles, D. E., Mikoshiba, K., Offermanns, S., & Yau, K. (2017) · Current Biology · doi:10.1016/j.cub.2017.05.022 · Cited by 40

Disrupted Calcium Signaling in Animal Models of Human Spinocerebellar Ataxia (SCA)

Prestori, F., Moccia, F. D., & D'Angelo, E. U. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010216 · Cited by 40

Carbamazepine prevents breakdown of neurotransmitter release induced by hyperactivation of ryanodine receptor

Yoshida, S., Okada, M., Zhu, G., & Kaneko, S. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.02.009 · Cited by 40

Skeletal Muscle IP3R1Receptors Amplify Physiological and Pathological Synaptic Calcium Signals

Zhu, H., Bhattacharyya, B. J., Lin, H., & Gomez, C. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3766-11.2011 · Cited by 38

Recent molecular approaches to understanding astrocyte function in vivo

Davila, D., Thibault, K., Fiacco, T. A., & Agulhon, C. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00272 · Cited by 42

A de novo missense mutation in the inositol 1,4,5‐triphosphate receptor type 1 gene causing severe pontine and cerebellar hypoplasia: Expanding the phenotype of ITPR1‐related spinocerebellar ataxia's

van Dijk, T., Barth, P. G., Reneman, L., Appelhof, B., Baas, F., & Poll‐The, B. T. (2016) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.37962 · Cited by 38

Virtual NEURON: a strategy for merged biochemical and electrophysiological modeling

Brown, S.-A. N., Moraru, I. I., Schaff, J. C., & Loew, L. M. (2011) · Journal of Computational Neuroscience · doi:10.1007/s10827-011-0317-0 · Cited by 37

Ca2+ signaling and spinocerebellar ataxia

Hisatsune, C., Hamada, K., & Mikoshiba, K. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2018.05.009 · Cited by 38

Gene disruption in mice: Models of development and disease

Shastry, B. S. (1998) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006865210012 · Cited by 37

Inositol-1,4,5-Trisphosphate Receptor-Mediated Ca Mobilization Is Not Required for Cerebellar Long-Term Depression in Reduced Preparations

Narasimhan, K., Pessah, I. N., & Linden, D. J. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.6.2963 · Cited by 37

Loss of IP3 Receptor–Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function

Tang, H., Wang, H., Lin, Q., Fan, F., Zhang, F., Peng, X., Fang, X., Liu, J., & Ouyang, K. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700109 · Cited by 37

The InsP3 receptor: its role in neuronal physiology and neurodegeneration

Banerjee, S., & Hasan, G. (2005) · BioEssays · doi:10.1002/bies.20298 · Cited by 35

Dysmetria of thought: Correlations and conundrums in the relationship between the cerebellum, learning, and cognitive processing

Schmahmann, J. D. (1996) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00081851 · Cited by 36

Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice

Matsumoto, M., & Nagata, E. (1999) · Journal of Molecular Medicine · doi:10.1007/s001090050370 · Cited by 56

An Analysis of the Activity of Two Disease Associated Mutations of the Inositol 1,4,5-Trisphosphate Receptor Type-1

Nienaber, T., Betzenhauser, M. J., Wagner, L. E., & Yule, D. I. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2009.12.2795 · Cited by 1

IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice

Hisatsune, C., Miyamoto, H., Hirono, M., Yamaguchi, N., Sugawara, T., Ogawa, N., Ebisui, E., Ohshima, T., Yamada, M., Hensch, T. K., et al. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00156 · Cited by 59

The Type 1 Inositol 1,4,5-Trisphosphate Receptor Gene Is Altered in theopisthotonosMouse

Street, V. A., Bosma, M. M., Demas, V., Regan, M. R., Lin, D. D., Robinson, L. C., Agnew, W. S., & Tempel, B. L. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-02-00635.1997 · Cited by 131

Widespread expression of inositol 1,4,5-trisphosphate receptor type 1 gene (Insp3r1) in the mouse central nervous system.

Furuichi, T., Simon‐Chazottes, D., Fujino, I., Yamada, N., Hasegawa, M. L., Miyawaki, A., Yoshikawa, S., Jl, G., & Mikoshiba, K. (1993) · PubMed · Cited by 200