p73 is a human p53-related protein that can induce apoptosis

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The presence of an intronic deletion in p73 and high levels of ZEB1 alter the TAp73/ΔTAp73 ratio in colorectal carcinomas

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p73 mutations are not detected in sporadic and hereditary breast cancer

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p73β, a Variant of p73, Enhances Wnt/β-Catenin Signaling in Saos-2 Cells

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Tyrosine kinase inhibitors in the treatment of chronic myeloid leukaemia: so far so good?

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Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control

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Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma

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Role of p53 and p73 genes polymorphisms in susceptibility to esophageal cancer: a case control study in a northern Indian population

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BAX and Tumor Suppressor TRP53 Are Important in Regulating Mutagenesis in Spermatogenic Cells in Mice1

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TIP60 Represses Transcriptional Activity of p73β via an MDM2-bridged Ternary Complex

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MCL1 binds and negatively regulates the transcriptional function of tumor suppressor p73

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Differential expression of p53, p63 and p73 protein and mRNA for DMBA‐induced hamster buccal‐pouch squamous‐cell carcinomas

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Induction of p73β by a naphthoquinone analog is mediated by E2F‐1 and triggers apoptosis in HeLa cells

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Screening for neuroblastoma: progress and pitfalls.

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NBP is the p53 homolog p63

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Lack of Homozygously Inactivated p73 in Single-Copy MYCN Primary Neuroblastomas and Neuroblastoma Cell Lines

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CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

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Distinct Chromosomal Profiles in Metastasizing and Non‐Metastasizing Colorectal Carcinomas

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p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

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STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death

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Rapid expansion of T cells: Effects of culture and cryopreservation and importance of short-term cell recovery

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The TP73 complex network: Ready for clinical translation in cancer?

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The neurogene BTG2TIS21/PC3 is transactivated by ΔNp73α via p53 specifically in neuroblastoma cells

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Telomerase activation and cell proliferation during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis

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Different intracellular compartmentalization of TA and ΔNp73 in non-small cell lung cancer

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Targeted Deletion of p73 in Mice Reveals Its Role in T Cell Development and Lymphomagenesis

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Functional implication of p73 protein stability in neuronal cell survival and death

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Detection of tenascin-C isoforms in colorectal mucosa, ulcerative colitis, carcinomas and liver metastases

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Epigenetic aberrations in natural killer/T-cell lymphoma: diagnostic, prognostic and therapeutic implications

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Interaction of mutant p53 with p73: A Surface Plasmon Resonance and Atomic Force Spectroscopy study

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p73α regulates the sensitivity of bone marrow mesenchymal stem cells to DNA damage agents

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The Diverse Functions of Mutant 53, Its Family Members and Isoforms in Cancer

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The Undervalued Avenue to Reinstate Tumor Suppressor Functionality of the p53 Protein Family for Improved Cancer Therapy-Drug Repurposing

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Tyr99 phosphorylation determines the regulatory milieu of tumor suppressor p73

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Expression of TAp73 and ΔNp73 isoform transcripts in thyroid tumours

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Differential effects of diverse p53 isoforms on TAp73 transcriptional activity and apoptosis

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Clinical and molecular features of mucosa‐associated lymphoid tissue (MALT) lymphomas of salivary glands

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A sequence element of p53 that determines its susceptibility to viral oncoprotein-targeted degradation

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Analysis of CDKN1A polymorphisms

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Radiation-induced G1 arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations

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Induction of Apoptosis in Melanoma Cell Lines by p53 and its Related Proteins

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Cerebellar cell lines established from a p53-deficient adult mouse

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Epigenetic Abnormalities in Chondrosarcoma

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Tumor Suppressors p53, p63TAα, p63TAy, p73α, and p73β Use Distinct Pathways to Repress Telomerase Expression

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TAp73 inhibits cell invasion and migration by directly activating KAI1 expression in colorectal carcinoma

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TAp73 Induction by Nitric Oxide

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p73 G4C14‐to‐A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck

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Plasmodium-infected erythrocytes (pRBC) induce endothelial cell apoptosis via a heme-mediated signaling pathway

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Molecular Regulation of Cell Death and Therapeutic Strategies for Cell Death Induction in Prostate Carcinoma

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p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes

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Allelic losses as prognostic markers for breast cancers

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Filamin A negatively regulates the transcriptional activity of p73α in the cytoplasm

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Overexpression of p73 enhances cisplatin-induced apoptosis in HeLa cells

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Reactivation of mutant p53 by a one-hybrid adaptor protein.

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Amphiphysin IIb-1, a novel splicing variant of amphiphysin II, regulates p73β function through protein-protein interactions

Kim, K., Kim, T.-S., Kang, K., & Choi, K. (2001) · Oncogene · doi:10.1038/sj.onc.1204839 · Cited by 15

p73α is a candidate effector in the p53 independent apoptosis pathway of cisplatin damaged primary murine colonocytes

Oniscu, A., Sphyris, N., Morris, R. G., Bader, S. A., & Harrison, D. J. (2004) · Journal of Clinical Pathology · doi:10.1136/jcp.2003.012559 · Cited by 16

Activating transcription factor 3 inhibits NF‑κB p65 signaling pathway and mediates apoptosis and cell cycle arrest in cervical cancer cells

Arsanjani, A. A., Abuei, H., Behzad‐Behbahani, A., Bagheri, Z., Arabsolghar, R., & Farhadi, A. (2022) · Infectious Agents and Cancer · doi:10.1186/s13027-022-00475-7 · Cited by 15

Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL

Yoon, M.-K., Kim, B.-Y., Lee, J.-Y., Ha, J., Kim, S. A., Lee, D.-H., Lee, M.-S., Lee, M., Choi, J. S., Cho, J. H., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.003061 · Cited by 15

p53-Related Transcription Targets of TAp73 in Cancer Cells—Bona Fide or Distorted Reality?

Wang, C., Teo, C. R., & Sabapathy, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041346 · Cited by 15

Whole-exome sequencing and bioinformatics analysis of a case of non-alpha-fetoprotein-elevated lung hepatoid adenocarcinoma

Yao, Y., Guan, X., Bao, G., Liang, J., Li, T. X., & Zhong, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.945038 · Cited by 15

Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus

Huang, Z., Gao, M., Li, Q., Tao, K., Xiao, Q., Cao, W., & Feng, W. (2013) · Oncotarget · doi:10.18632/oncotarget.1339 · Cited by 15

Association of Combined p73 and p53 Genetic Variants with Tumor HPV16-Positive Oropharyngeal Cancer

Wang, Z., Sturgis, E. M., Guo, W., Song, X., Zhang, F., Xu, L., Wei, Q., & Li, G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035522 · Cited by 15

Redox state of p63 and p73 core domains regulates sequence-specific DNA binding

Tichý, V., Navrátilová, L., Adámik, M., Fojta, M., & Brázdová, M. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.02.097 · Cited by 15

Functional characterization of naturally occurring mutants (P405R and P425L) of p73α and p73β found in neuroblastoma and lung cancer

Naka, M., Ozaki, T., Takada, N., Takahashi, M., Shishikura, T., Sakiyama, S., Tada, M., Todo, S., & Nakagawara, A. (2001) · Oncogene · doi:10.1038/sj.onc.1204470 · Cited by 15

Overexpression of p16INK4a correlates with high expression of p73 in breast carcinomas

García‐Barberán, V., Silva, J., Domínguez, G., García, J. M., Peña, C., Rodríguez, R., Provencio, M., España, P., & Bonilla, F. (2004) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.04.008 · Cited by 15

p63 and p73, members of the p53 gene family, transactivate PKCδ

Ponassi, R., Terrinoni, A., Chikh, A., Rufini, A., Lena, A. M., Sayan, B. S., Melino, G., & Candi, E. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.07.031 · Cited by 15

Detection of Epstein-Barr virus (EBV) genomes in the serum of patients with EBV-associated Hodgkin's disease

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p53CP is p51/p63, the third member of the p53 gene family: partial purification and characterization

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Relationship between TP73 polymorphism (G4C14–A4T14) and cancer risk: A meta-analysis based on literatures

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MYCN is amplified during S phase, and c‑myb is involved in controlling MYCN expression and amplification in MYCN‑amplified neuroblastoma cell lines

Aygün, N., & Altungöz, O. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9686 · Cited by 14

P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition

Zhang, Y., Young, A. M., Zhang, J., & Chen, X. (2015) · Oncotarget · doi:10.18632/oncotarget.4374 · Cited by 14

Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc -induced lymphomas

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p53 Pathway Alterations in Brain Tumors

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Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target

Sasaki, Y., Tamura, M., Takeda, K., Ogi, K., Nakagaki, T., Koyama, R., Idogawa, M., Hiratsuka, H., & Tokino, T. (2016) · Oncotarget · doi:10.18632/oncotarget.11366 · Cited by 15

Interplay Between the p53 Tumor Suppressor Protein Family and Cdk5: Novel Therapeutic Approaches for the Treatment of Neurodegenerative Diseases Using Selective Cdk Inhibitors

Węsierska‐Gądek, J., Strosznajder, J. B., & Schmid, G. (2006) · Molecular Neurobiology · doi:10.1385/mn:34:1:27 · Cited by 14

Apoptosis in neuroendocrine tumours

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p53 is involved in clearance of ionizing radiation-induced RAD51 foci in a human colon cancer cell line

Orre, L. M., Stenerlöw, B., Dhar, S., Larsson, R. L., Lewensohn, R., & Lehtiö, J. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.085 · Cited by 14

Novel Cell-specific and Dominant Negative Anti-apoptotic Roles of p73 in Transformed Leukemia Cells

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The role of wild-type and mutated N-ras in the malignant transformation of liver cells

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Molecular Mechanisms Responsible for In Vitro Cytotoxic Attributes of Conyza bonariensis Extract against Lymphoblastic Leukaemia Jurkat Cells

Saleem, M., Schini‐Kerth, V. B., Hussain, K., Khalid, S. H., Asif, M., Alhosin, M., Akhtar, M. F., Ahmad, B., Raza, A., & Mahrukh, M. (2021) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520621666210906092314 · Cited by 13

Possible involvement of ΔNp63 downregulation in the invasion and metastasis of oral squamous cell carcinoma via induction of a mesenchymal phenotype

Goto, Y., Kawano, S., Matsubara, R., Kiyosue, T., Hirano, M., Jinno, T., Maruse, Y., Toyoshima, T., Kitamura, R., Tanaka, H., et al. (2013) · Clinical & Experimental Metastasis · doi:10.1007/s10585-013-9628-z · Cited by 13

Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia

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Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers

Persson, M., Andersson, M. K., Sahlin, P., Mitani, Y., Brandwein‐Weber, M., Frierson, H. F., Moskaluk, C. A., Fonseca, I., Ferrarotto, R., Boecker, W., et al. (2023) · The Journal of Pathology · doi:10.1002/path.6172 · Cited by 13

p63 and p73 in Tumor Suppression and Promotion

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The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan

Song, G., Valdez, B. C., Li, Y., Dominguez, J. R., Corn, P. G., Champlin, R. E., & Andersson, B. S. (2013) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2013.856007 · Cited by 13

Neuronal Activity: From In Vitro Preparation to Behaving Animals

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Kinase activity-independent suppression of p73α by AMP-activated kinase α (AMPKα)

Lee, Y.-G., Lee, S.-W., Sin, H.-S., Kim, E., & Um, S.-J. (2008) · Oncogene · doi:10.1038/onc.2008.452 · Cited by 13

Alteration of p73 in pediatric de novo acute lymphoblastic leukemia

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Pattern of Expression of p53, Its Family Members, and Regulators during Early Ocular Development and in the Post-Mitotic Retina

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Combination treatment with auranofin and nutlin-3a induces synergistic cytotoxicity in breast cancer cells

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TAp73β-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics

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Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy

Liang, J., Parchaliuk, D. L., Medina, S. J., Sorensen, G., Landry, L., Huang, S., Wang, M., Kong, Q., & Booth, S. A. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-201 · Cited by 13

Differential regulation of transcription and induction of programmed cell death by human p53‐family members p63 and p73

Dietz, S., Rother, K., Bamberger, C., Schmale, H., Mössner, J., & Engeland, K. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03093-4 · Cited by 59

New Monoclonal Antibodies Recognizing the p53 Tumour Suppressor Protein Homologue p73

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p73, a sophisticated p53 family member in the cancer world

Ozaki, T., & Nakagawara, A. (2005) · Cancer Science · doi:10.1111/j.1349-7006.2005.00116.x · Cited by 141

p73 can suppress the proliferation of cells that express mutant p53

Willis, A. C., Pipes, T., Zhu, J., & Chen, X. (2003) · Oncogene · doi:10.1038/sj.onc.1206505 · Cited by 25

The Emerging p53 Gene Family

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