p73 is a human p53-related protein that can induce apoptosis

Jost, Christine A., Marin, Maria C., Jr, William G. Kaelin·1997·Nature

Cited by (943)

Items 101–200 of 943

  1. p73 Is Required for Survival and Maintenance of CNS Neurons
    Christine D. Pozniak, Fanie Barnabé‐Heider, Vladimir V. Rymar, Anna F. Lee, Abbas F. Sadikot, Freda D. Miller · 2002 · Journal of Neuroscience
  2. NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas
    Paola Leone, Maria Josefa Bello, José M. de Campos, Jesús Vaquero, Jose L Sarasa, Ángel Pestaña, JUAN ANTONIO REY · 1999 · Oncogene
  3. p53 in embryonic development: maintaining a fine balance
    Jong Min Choi, Lawrence A. Donehower · 1999 · Cellular and Molecular Life Sciences
  4. p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network
    Clayton B. Marshall, Deborah J. Mays, J. Scott Beeler, Jennifer M. Rosenbluth, Kelli Lynn Boyd, Gabriela L. Santos Guasch, Timothy M. Shaver, Lucy J. Tang, Qi Liu, Yu Shyr et al. · 2016 · Cell Reports
  5. Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1
    Mahmoud Alhosin, Abdurazzag Abusnina, Mayada Achour, Tanveer Sharif, Christian Dominique Muller, Jean Peluso, Thierry Chataigneau, Claire Lugnier, Valérie B. Schini‐Kerth, Christian Bronner et al. · 2009 · Biochemical Pharmacology
  6. TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity
    Richard Tomasini, Mylène Seux, Jonathan Nowak, Caroline Bontemps, Alice Carrier, Jean–Charles Dagorn, Marie‐Josèphe Pébusque, Juan Iovanna, Nelson Dusetti · 2005 · Oncogene
  7. Igfbp-3 mediates TGFβ1 proliferative response in colon cancer cells
    Sanjay Kansra, Daina Z. Ewton, Jingping Wang, Eileen Friedman · 2000 · International Journal of Cancer
  8. Identification of Direct p73 Target Genes Combining DNA Microarray and Chromatin Immunoprecipitation Analyses
    Giulia Fontemaggi, Itai Kela, Ninette Amariglio, Gideon Rechavi, Janakiraman Krishnamurthy, Sabrina Strano, Ada Sacchi, David Givol, Giovanni Blandino · 2002 · Journal of Biological Chemistry
  9. The Emerging p53 Gene Family
    William G. Kaelin · 1999 · JNCI Journal of the National Cancer Institute
  10. p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis
    Xiaohua Su, Deepavali Chakravarti, Elsa Renee Flores · 2013 · Nature reviews. Cancer
  11. Overexpression of the wild type p73 gene in human bladder cancer
    Akira Yokomizo, Ming Mai, Donald J. Tindall, Liang Cheng C, David G. Bostwick, Seiji Naito, David I Smith, Wanguo Liu · 1999 · Oncogene
  12. Oncogenes Induce and Activate Endogenous p73 Protein
    Alexander I. Zaika, Meredith S. Irwin, Christine Sansome, Ute Martha Moll · 2001 · Journal of Biological Chemistry
  13. c-Abl: activation and nuclear targets
    Yosef Shaul · 2000 · Cell Death and Differentiation
  14. Transdominant ΔTAp73 Isoforms Are Frequently Up-regulated in Ovarian Cancer. Evidence for Their Role as Epigenetic p53 Inhibitors in Vivo
    Nicole Concin, Kirsten Becker, Neda Slade, Susan H. Erster, Elizabeth Mueller-Holzner, Hanno Ulmer, Guenter Daxenbichler, Alain Gustave Zeimet, Robert Zeillinger, Christian Marth et al. · 2004 · Cancer Research
  15. p63 and p73 Transcriptionally Regulate Genes Involved in DNA Repair
    Yu‐Li Lin, Shomit Sengupta, Katherine Gurdziel, George W. Bell, Tyler Jacks, Elsa Renee Flores · 2009 · PLoS Genetics · Retracted
  16. p63 and p73 Transactivate Differentiation Gene Promoters in Human Keratinocytes
    Vincenzo De Laurenzi, Antonello Rossi, Alessandro Terrinoni, Daniela Barcaroli, Massimo Levrero, Antonio Costanzo, Richard A. Knight, Pietro Guerrieri, Gerry Melino · 2000 · Biochemical and Biophysical Research Communications
  17. Genetic Alterations in Esophageal Cancer
    Hiroyuki Kuwano, Hiroyuki Kato, Tatsuya Miyazaki, Minoru Fukuchi, Norihiro Masuda, Masanobu Nakajima, Yasuyuki Fukai, Makoto Sohda, Hitoshi Kimura, Ahmad Faried · 2004 · Surgery Today
  18. p73, a sophisticated p53 family member in the cancer world
    Toshinori Ozaki, Akira Nakagawara · 2005 · Cancer Science
  19. MDM2 and MDMX bind and stabilize the p53-related protein p73
    Weg M. Ongkeko, Xiao Qi Wang, Wai Yi Siu, Anita W.S. Lau, Katsumi Yamashita, Adrian Llewellyn Harris, Lynne S. Cox, Randy Y.C. Poon · 1999 · Current Biology
  20. Targeting p53 for enhanced radio- and chemo-sensitivity
    Chao Lü, Wafik S. El‐Deiry · 2009 · APOPTOSIS
  21. Inactivation of p53 but Not p73 by Adenovirus Type 5 E1B 55-Kilodalton and E4 34-Kilodalton Oncoproteins
    Judith C. Roth, Claudia König, Sandra Wienzek‐Lischka, Silke Weigel, Susanne Ristea, Matthias Dobbelstein · 1998 · Journal of Virology
  22. Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis
    Hong-Ran Choi, John G. Batsakis, Feng Zhan, Erich M. Sturgis, Mario Armando Luna, Adel K. El‐Naggar · 2002 · Human Pathology
  23. Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders
    Jonathan N. Glickman, Annie Yang, Aliakbar Shahsafaei, Frank McKeon, Robert Daniel Odze · 2001 · Human Pathology
  24. Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.
    S Kovalev, N D Marchenko, Steven L. Swendeman, Michael P. LaQuaglia, Ute Martha Moll · 1998 · PubMed
  25. Mismatch Repair Processing of Carcinogen-DNA Adducts Triggers Apoptosis
    Jianxin Wu, Liya Gu, Huixian Wang, Nicholas E. Geacintov, Guo‐Min Li · 1999 · Molecular and Cellular Biology
  26. Evolution of Functions within the p53/p63/p73 Family
    Vincenzo De Laurenzi, Gerry Melino · 2000 · Annals of the New York Academy of Sciences
  27. Developmental Roles of p73 in Cajal-Retzius Cells and Cortical Patterning
    Gundela Meyer, Alfredo Cabrera Socorro, Carlos G. Pérez‐García, Luis Martínez Millán, Nancy Walker, Daniel Caput · 2004 · Journal of Neuroscience
  28. p53 induces the expression of its antagonist p73ΔN, establishing an autoregulatory feedback loop
    Natalia N Kartasheva, Ana Contente, Claudia Lenz-Stöppler, Judith C. Roth, Matthias Dobbelstein · 2002 · Oncogene
  29. Tetramer formation of tumor suppressor protein p53: Structure, function, and applications
    Rui Kamada, 侑 戸口, Takao Nomura, Toshiaki Imagawa, Kazuyasu Sakaguchi · 2015 · Biopolymers
  30. HTLV-1 Tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration
    Yasuo Ariumi, Atsushi Kaida, Jye-Yee Lin, Masami Hirota, Osamu Masui, Shoji Yamaoka, Yoichi Taya, Kunitada Shimotohno · 2000 · Oncogene
  31. Structure, function and regulation of p63 and p73
    Massimo Levrero, Vincenzo De Laurenzi, Antonio Costanzo, Ji‐Ming Gong, Gerry Melino, J Y J Wang · 1999 · Cell Death and Differentiation
  32. Meningiomas May Be a Component Tumor of Multiple Endocrine Neoplasia Type 1
    Behnam Asgharian, Yuan‐Jia Chen, Nicholas J. Patronas, Paolo L. Peghini, James C. Reynolds, Alexander O. Vortmeyer, Zhengping Zhuang, David J. Venzon, Fathia Gibril, Robert T. Jensen · 2004 · Clinical Cancer Research
  33. Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression
    Michimasa Nozaki, Mitsuhiro Tada, Hiroyuki Kobayashi, C L Zhang, Yutaka Sawamura, Hiroshi Abe, Nobuaki Ishii, Erwin G. Van Meir · 1999 · Neuro-Oncology
  34. p53 induces TAP1 and enhances the transport of MHC class I peptides
    Kuichun Zhu, Jian Wang, Jianhui Zhu, Jieyuan Jiang, Jiang Shou, Xinbin Chen · 1999 · Oncogene
  35. Transactivation-deficient p73α (p73Δexon2) inhibits apoptosis and competes with p53
    I Filippovitch, Natasha Sorokina, Magtouf Hnaidi Gatei, Ygal Haupt, Karen Hobson, Eli Moallem, Kevin J. Spring, Michelle A Mould, Michael A. McGuckin, Martin Francis Lavin et al. · 2001 · Oncogene
  36. Mdm2-mediated NEDD8 Modification of TAp73 Regulates Its Transactivation Function
    Ian R. Watson, Alvaro Blanch, Dan C.C. Lin, Michael Ohh, Meredith S. Irwin · 2006 · Journal of Biological Chemistry
  37. Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans
    Hans van Bokhoven, Frank McKeon · 2002 · Trends in Molecular Medicine
  38. A Second p53-Related Protein, p73L, with High Homology to p73
    Makoto Senoo, Naohiko Seki, Miki Ohira, Sumio Sugano, Manabu Watanabe, Makoto Tachibana, Takashi Tanaka, Yoichi Shinkai, Hiroyuki Kato · 1998 · Biochemical and Biophysical Research Communications
  39. p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent
    Shingo Ichimiya, Yoshinori Nimura, Hajime Kageyama, Naoyuki Takada, Masao Sunahara, Tomotane Shishikura, Yohko Nakamura, Shigeru Sakiyama, Naohiko Seki, Miki Ohira et al. · 1999 · Oncogene
  40. The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation
    Giulia Fontemaggi, Aymone Gurtner, Sabrina Strano, Yujiro Higashi, Ada Sacchi, Giulia Piaggio, Giovanni Blandino · 2001 · Molecular and Cellular Biology
  41. Ubiquitin-dependent Degradation of p73 Is Inhibited by PML
    Francesca Bernassola, Paolo Salomoni, Andrew Oberst, Charles J. Di Como, Michele Pagano, Gerry Melino, Pier Paolo Pandolfi · 2004 · The Journal of Experimental Medicine
  42. Adenovirus and cell cycle control
    Haggit Ben-Israel · 2002 · Frontiers in bioscience
  43. The p53 family in nervous system development and disease
    W. Bradley Jacobs, David R. Kaplan, Freda D. Miller · 2006 · Journal of Neurochemistry
  44. DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis
    Estelle Schmitt, Claudie Paquet, Myriam Beauchemin, Richard Bertrand · 2007 · Journal of Zhejiang University SCIENCE B
  45. p53, p63 and p73 – solos, alliances and feuds among family members
    Ute Martha Moll, Susan H. Erster, Alex Zaika · 2001 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  46. p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA Damage
    Jian Ren, Rakesh Datta, Hisashi Shioya, Yongqing Li, Eiji Oki, Verena Biedermann, Ajit K. Bharti, Donald W. Kufe · 2002 · Journal of Biological Chemistry
  47. TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
    Marta Majdan, Gregory S. Walsh, Raquel S. Aloyz, Freda D. Miller · 2001 · The Journal of Cell Biology
  48. The transcriptional activities of p53 and its homologue p51/p63: similarities and differences.
    Akira Shimada, Shunsuke Kato, Kentaro Enjo, M Osada, Yoji Ikawa, Kimitoshi Kohno, Masuo Obinata, Ryunosuke Kanamaru, Shuntaro Ikawa, Chikashi Ishioka · 1999 · PubMed
  49. A Gene Signature-Based Approach Identifies mTOR as a Regulator of p73
    Jennifer M. Rosenbluth, Deborah J. Mays, Maria F. Pino, Luo Jia Tang, Jennifer A. Pietenpol · 2008 · Molecular and Cellular Biology
  50. ΔTAp73 Upregulation Correlates With Poor Prognosis in Human Tumors: Putative In Vivo Network Involving p73 Isoforms, p53, and E2F-1
    Gemma Domínguez, José M. García, Cristina Peña, Javier Silva, Vanesa García‐Barberán, Lara Martínez, Constanza Maximiano, M. Escobar Gomez, José A. Rivera, Carmen García-Andrade et al. · 2005 · Journal of Clinical Oncology
  51. Identification of Three Functions of the Adenovirus E4orf6 Protein That Mediate p53 Degradation by the E4orf6-E1B55K Complex
    Emmanuelle Querido, Megan R. Morrison, Huan Chu Pham Dang, Sarah W.-L. Thirlwell, Dominique Boivin, Philip E. Branton · 2001 · Journal of Virology
  52. Analysis of p53/BAX/p16ink4a/CDKN2 in Esophageal Squamous Cell Carcinoma: High BAX and p16ink4a/CDKN2 Identifies Patients With Good Prognosis
    Isrid Sturm, Henrik Petrowsky, Roland Volz, Matthias Lorenz, Silke Radetzki, Timo Hillebrand, G. Wolff, Steffen Hauptmann, Bernd Dörken, Peter T. Daniel · 2001 · Journal of Clinical Oncology
  53. p73 or p53 Directly Regulates Human p53 Transcription to Maintain Cell Cycle Checkpoints
    Shulin Wang, Wafik S. El‐Deiry · 2006 · Cancer Research
  54. DNA mismatch repair system
    Sung‐Hoon Jun, Tae‐Gyun Kim, Changill Ban · 2006 · FEBS Journal
  55. Correlation between Clinicopathological Features and Karyotype in Spindle Cell Sarcomas
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  56. Manganese Superoxide Dismutase Is a p53 -Regulated Gene That Switches Cancers between Early and Advanced Stages
    Dhar, Sanjit K., Tangpong, Jitbanjong, Chaiswing, Luksana, Oberley, Terry D., St. Clair, Daret K. · 2011 · Cancer Research
  57. P63 gene mutations and human developmental syndromes
    Brunner, Han G., Hamel, Ben C.J., Bokhoven, Hans van · 2002 · American Journal of Medical Genetics
  58. Extracts of Strawberry Fruits Induce Intrinsic Pathway of Apoptosis in Breast Cancer Cells and Inhibits Tumor Progression in Mice
    Ranganatha R. Somasagara, Mahesh Bhaskar Hegde, Kishore Kumar CHIRUVELLA, Anjaneyulu Musini, Bibha Choudhary, Sathees C. Raghavan · 2012 · PLoS ONE
  59. Genetic and epigenetic changes in stomach cancer
    Hiroshi Yokozaki, Wataru Yasui, Eiichi Tahara · 2001 · International review of cytology
  60. ΔNp73β Is Active in Transactivation and Growth Suppression
    Gang Liu, Susan E. Nozell, Hui Xiao, Xinbin Chen · 2003 · Molecular and Cellular Biology
  61. Mutation analysis of P73 and TP53 in Merkel cell carcinoma
    Mireille Van Gele, Mourad Kaghad, J. Helen Leonard, Nadine Van Roy, J.M. Naeyaert, M. L. Geerts, Simon Van Belle, V.F.J. Cocquyt, Julia A. Bridge, Raf Sciot et al. · 2000 · British Journal of Cancer
  62. ΔNp73 Facilitates Cell Immortalization and Cooperates with Oncogenic Ras in Cellular Transformation In Vivo
    Oleksi Petrenko, Alexander I. Zaika, Ute Martha Moll · 2003 · Molecular and Cellular Biology
  63. A novel HECT-type E3 ubiquitin ligase, NEDL2, stabilizes p73 and enhances its transcriptional activity
    Kou Miyazaki, Toshinori Ozaki, Chiaki Kato, Takayuki Hanamoto, Tomoyuki Fujita, S Irino, Kenichi Watanabe, Takahito Nakagawa, Akira Nakagawara · 2003 · Biochemical and Biophysical Research Communications
  64. p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
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  65. Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1
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  66. Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck
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  67. HMGA1 Inhibits the Function of p53 Family Members in Thyroid Cancer Cells
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  68. p53-Mediated Regulation of Proliferating Cell Nuclear Antigen Expression in Cells Exposed to Ionizing Radiation
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  69. Tumor Protein 53-Induced Nuclear Protein 1 Enhances p53 Function and Represses Tumorigenesis
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  70. Regulation of Apoptosis in Prostate Cancer
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  72. The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis
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  73. Induction of p57 KIP2 expression by p73β
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  74. Association ofp53 codon arg72pro andp73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of japanese breast cancer
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  75. p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor
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  76. Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins
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  77. p73 is transcriptionally regulated by DNA damage, p53, and p73
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  78. The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function
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  81. P73 functionally replaces p53 in Adriamycin‐treated, p53‐deficient breast cancer cells
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  82. Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia.
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  84. Regulation and activation of p53 and its family members
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  85. Expression of homologues for p53 and p73 in the softshell clam (Mya arenaria), a naturally-occurring model for human cancer
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  86. From p63 to p53 across p73
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  87. Survivin regulates the p53 tumor suppressor gene family
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  88. Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53
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  89. Expression of ΔNp73 Predicts Poor Prognosis in Lung Cancer
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  97. Role of the newer p53 family proteins in malignancy
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  98. Binding of the C-terminal Sterile α Motif (SAM) Domain of Human p73 to Lipid Membranes
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  99. MDM2 Antagonist Nutlin-3 Displays Antiproliferative and Proapoptotic Activity in Mantle Cell Lymphoma
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  100. Identification and Characterization of HIPK2 Interacting with p73 and Modulating Functions of the p53 Familyin Vivo
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