p73 is a human p53-related protein that can induce apoptosis

Jost, Christine A., Marin, Maria C., Jr, William G. Kaelin·1997·Nature

Cited by (943)

Items 501–600 of 943

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  2. TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity
    Dongshi Chen, Lihua Ming, Fangdong Zou, Peng Ye, Bennett Van Houten, Jian Yu, Lin Zhang · 2014 · Oncotarget
  3. Diallyl disulfide enhances carbon ion beams–induced apoptotic cell death in cervical cancer cells through regulating Tap73 /ΔNp73
    Cuixia Di, Chao Sun, Hongyan Li, Jing Si, Hong Zhang, Lu Han, Qiuyue Zhao, Liu Yang, Bin Liu, Guoying Miao et al. · 2015 · Cell Cycle
  4. The role of wild-type p53 in the differentiation of primary hemopoietic and muscle cells
    Giuseppina Mazzaro, Gianluca Bossi, Sabrina Coen, Ada Sacchi, Silvia Soddu · 1999 · Oncogene
  5. Critical roles of Wnt5a–Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ΔNp63β-mediated epithelial–mesenchymal transition
    Taiki Sakamoto, Shintaro Kawano, Ryota Matsubara, Yuichi Goto, Teppei Jinno, Yasuyuki Maruse, Naoki Kaneko, Yuma Hashiguchi, Taichi Hattori, Shoichi Tanaka et al. · 2017 · Oral Oncology
  6. Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras
    Tongbo Zhu, T Tsuji, Changyan Chen · 2009 · Oncogene
  7. p73 Interacts with Human Immunodeficiency Virus Type 1 Tat in Astrocytic Cells and Prevents Its Acetylation on Lysine 28
    Shohreh Amini, Giuseppe Mameli, Luis Del Valle, Anna Skowrońska, Krzysztof Reiss F, Benjamin B. Gelman, Martyn K. White, Kamel Khalili, Bassel E. Sawaya · 2005 · Molecular and Cellular Biology
  8. HtrA2 enhances the apoptotic functions of p73 on bax
    Mirko Marabese, Marco Mazzoletti, Faina Vikhanskaya, Massimo Broggini · 2008 · Cell Death and Differentiation
  9. The Role of E3, E4 Ubiquitin Ligase (UBE4B) in Human Pathologies
    N. G. Antoniou, Nefeli Lаgopati, Dimitrios-Ilias Balourdas, Michail Nikolaou, Alexandros Papalampros, Panagiotis V. S. Vasileiou, Vassilios Myrianthopoulos, Athanassios Kotsinas, Yosef Shiloh, Michalis Liontos et al. · 2019 · Cancers
  10. The Cul4A–DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity
    Martina Malatesta, Angelo Peschiaroli, Elisa Maria Memmi, Jinsong Zhang, A Antonov, Douglas R. Green, Nickolai A. Barlev, A. V. Garabadgiu, Pengbo Zhou, Gerry Melino et al. · 2012 · Oncogene
  11. Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1
    Shourong Wu, Saomi Murai, Kazunori Kataoka, Makoto Miyagishi · 2007 · Biochemical and Biophysical Research Communications
  12. TAp73 isoforms antagonize Notch signalling in SH‐SY5Y neuroblastomas and in primary neurones
    Claudie Hooper, Mahvash Tavassoli, J. Paul Chapple, Dafe Uwanogho, Richard J. Goodyear, Gerry Melino, Simon Lovestone, Richard Killick · 2006 · Journal of Neurochemistry
  13. Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, Contribute to Risk of Cutaneous Melanoma
    Chunying Li, Kexin Chen, Zhensheng Liu, Li‐E Wang, Jeffrey E. Gershenwald, Jeffrey E. Lee, Victor Gerardo Prieto, Madeleine A. Duvic, Elizabeth Ann Grimm, Qingyi Wei · 2007 · Journal of Investigative Dermatology
  14. Functional analysis of p53 tumor suppressor in yeast
    Jana Šmardová, Jan Šmarda, Jana Koptíková · 2005 · Differentiation
  15. p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo
    Jesús Pérez‐Losada, Di Wu, Reyno Delrosario, Allan Balmain, Jian‐Hua Mao · 2005 · Oncogene
  16. Relief of p53-mediated Telomerase Suppression by p73
    Wen Hong Toh, Satoru Kyo, Kanaga Sabapathy · 2005 · Journal of Biological Chemistry
  17. Non-p53 p53RE binding protein, a human transcription factor functionally analogous to P53
    Xiaoya Zeng, Arnold J. Levine, Hua Lu · 1998 · Proceedings of the National Academy of Sciences
  18. Clinical implications of the deregulated TP73 isoforms expression in cancer
    Núria Rodríguez, A. Peláez, Rodrigo Barderas, Gemma Domínguez · 2017 · Clinical & Translational Oncology
  19. RETRACTED: MicroRNA-361-3p promotes human breast cancer cell viability by inhibiting the E2F1/P73 signalling pathway
    Bin Hua, Yao Li, Xin Yang, Xiaojuan Niu, Yanyang Zhao, Xiaoquan Zhu · 2020 · Biomedicine & Pharmacotherapy · Retracted
  20. Equilibrium Unfolding of the C-Terminal SAM Domain of p73
    Francisco N. Barrera, María T. Garzón, Javier Gómez, José L. Neira · 2002 · Biochemistry
  21. Enhancement of the radiosensitivity of cervical cancer cells by overexpressing p73α
    Stephanie Si Liu, Kelvin Y.K. Chan, Rebecca Ching-Yu Leung, Hkw Law, Tsin‐Wah Leung, Hys Ngan · 2006 · Molecular Cancer Therapeutics
  22. Analysis of p73 expression pattern in acute myeloid leukemias: lack of ΔN-p73 expression is a frequent feature of acute promyelocytic leukemia
    Maria Giulia Rizzo, Emanuela Giombini, Daniela Diverio, Marco Vignetti, Ada Sacchi, Ugo Testa, Francesco Lo‐Coco, Giovanni Blandino · 2004 · Leukemia
  23. PCAF is a coactivator for p73-mediated transactivation
    Lisa Zhao, Yue Liu, Nicholas Bertos, Xiang‐Jiao Yang, Daiqing Liao · 2003 · Oncogene
  24. N-myc Modulates Expression of p73 in Neuroblastoma
    Xiaoxiang Zhu, Katharina Wimmer, Rork D. Kuick, Barbara Lamb, Stephanie Motyka, Rama Jasty, Valerie P. Castle, Samir Hanash · 2002 · Neoplasia
  25. Transcription inhibition: A potential strategy for cancer therapeutics
    Frederick A. Derheimer, Ching‐Wei Chang, Mats E. Ljungman · 2005 · European Journal of Cancer
  26. p53: Emergency Brake and Target for Cancer Therapy
    Klas G. Wiman · 1997 · Experimental Cell Research
  27. Discussion of some ‘knowns’ and some ‘unknowns’ about the tumour suppressor p53
    Elizabeth Lieschke, Zilu Wang, Gemma L. Kelly, Andreas Strasser · 2018 · Journal of Molecular Cell Biology
  28. An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy
    Huiwen Li, Xinhui Cai, Xiaoyu Yang, Xuan Zhang · 2024 · European Journal of Medicinal Chemistry
  29. Virus against virus: strategies for using adenovirus vectors in the treatment of HPV-induced cervical cancer
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  30. Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) Tumorigenesis
    Dennis M. Timmerman, Tessa L. Remmers, Sanne Hillenius, Leendert H. J. Looijenga · 2021 · International Journal of Molecular Sciences
  31. Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition
    Jae‐Sun Shin, Ji‐Hyang Ha, Dong-Hwa Lee, Kyoung‐Seok Ryu, Kwang‐Hee Bae, Byoung Chul Park, Sung Goo Park, Gwan‐Su Yi, Seung‐Wook Chi · 2015 · Cell Cycle
  32. p73β-expressing recombinant adenovirus: a potential anticancer agent
    Sanjeev Das, Srikanth Nama, Sini Antony, Kumaravel Somasundaram · 2005 · Cancer Gene Therapy
  33. Runt‐related transcription factor 2 attenuates the transcriptional activity as well as DNA damage‐mediated induction of pro‐apoptotic TAp73 to regulate chemosensitivity
    Toshinori Ozaki, Hirokazu Sugimoto, Mizuyo Nakamura, Kiriko Hiraoka, Hiroyuki Yoda, Meixiang Sang, Kyoko Fujiwara, Hiroki Nagase · 2014 · FEBS Journal
  34. Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells
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  35. Efficient growth inhibition of HPV 16 E6-expressing cells by an adenovirus-expressing p53 homologue p73β
    Sanjeev Das, Wafik S. El‐Deiry, Kumaravel Somasundaram · 2003 · Oncogene
  36. HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX
    Gilad Doitsh, Yosef Shaul · 1999 · Oncogene
  37. Epigenetic Changes in Cancer and Preneoplasia
    James Gordon Herman · 2005 · Cold Spring Harbor Symposia on Quantitative Biology
  38. p73 cooperates with Ras in the activation of MAP kinase signaling cascade
    Fernandez-Garcia, B, Vaqué, J P, Herreros-Villanueva, M, Marques-Garcia, F, Castrillo, F, Fernandez-Medarde, A, León, J, Marín, M C · 2007 · Cell Death & Differentiation
  39. Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways
    Yin He, Xiangyu Cao, Yuchi Kong, S Wang, Ying Xia, Ruochen Bi, Jianli Liu · 2019 · Human & Experimental Toxicology
  40. Interplay between TAp73 Protein and Selected Activator Protein-1 (AP-1) Family Members Promotes AP-1 Target Gene Activation and Cellular Growth
    Deepa Subramanian, Wilawan Bunjobpol, Kanaga Sabapathy · 2015 · Journal of Biological Chemistry
  41. Multiple isoforms of the tumor protein p73 are expressed in the adult human telencephalon and choroid plexus and present in the cerebrospinal fluid
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  42. Design of a novel MDM2 binding peptide based on the p53 family
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  43. Differential expression of two new members of the p53 family, p63 and p73, in extramammary Paget’s disease
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  45. Association of p73 G4C14-to-A4T14 (GC/AT) polymorphism with breast cancer survival
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  46. Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or Apoptin
    Poramaporn Klanrit, Marcella Flinterman, Edward William Odell, Gerry Melino, Richard Killick, James Scott Norris, Mahvash Tavassoli · 2008 · Cell Cycle
  47. p53-Independent Induction of Apoptosis by the HTLV-I Tax Protein Following UV Irradiation
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  48. Regulation of the p53 Homolog p73 by Adenoviral Oncogene E1A
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  50. Compensatory Expression of p73 in PARP-Deficient Mouse Fibroblasts as Response to a Reduced Level of Regularly Spliced Wild-Type p53 Protein
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  51. TAp63γ can substitute for p53 in inducing expression of the maspin tumor suppressor
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  52. Inhibition of p63 Transcriptional Activity by p14ARF: Functional and Physical Link between Human ARF Tumor Suppressor and a Member of the p53 Family
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  53. p73: Structure and function
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  55. p73 can suppress the proliferation of cells that express mutant p53
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  56. Differential expression of p53, p63 and p73 proteins in human buccal squamous-cell carcinomas
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  57. p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription
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  58. Mutation and Expression of the p51 Gene in Human Lung Cancer
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  59. Allelic imbalance and instability of microsatellite loci on chromosome 1p in human non-small-cell lung cancer
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  60. p73 G4C14-A4T14 polymorphism and cancer risk: a meta-analysis based on 27 case-control studies
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  61. Dual Role of p73 in Cancer Microenvironment and DNA Damage Response
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  62. Regulation of ΔNp63α by NFκΒ
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  76. p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas
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  78. Transcriptional Regulation by p53 and p73
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  79. Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA
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  82. MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells
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  86. NF-κB regulates the stability and activity of p73 by inducing its proteolytic degradation through a ubiquitin-dependent proteasome pathway
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  88. Adenovirus E1-transformed cells grow despite the continuous presence of transcriptionally active p53
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  90. Refined chromosomal localization of the putative tumor suppressor gene TP73
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  95. Transactivation-dependent and -independent Regulation of p73 Stability
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  96. p73 expression for human buccal epithelial dysplasia and squamous cell carcinoma: Does it correlate with nodal status of carcinoma and is there a relationship with malignant change of epithelial dysplasia?
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  99. p73 Protein Expression Correlates With Radiation-Induced Apoptosis in the Lack of p53 Response to Radiation Therapy for Cervical Cancer
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