Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.
Walczak, Henning, Miller, Robert E., Ariail, Kiley, Gliniak, Brian, Griffith, Thomas S., Kubin, Marek, Chin, Wilson, Jones, Jon +8 more·1999·Nature Medicine
DOI 10.1038/5517
Cited by (1,003)
Items 501–600 of 1,003
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- Recent progress in nanomedicine-based combination cancer therapy using a site-specific co-delivery strategyShiyang Shen, Meng Liu, Teng Li, Shiqi Lin, Ran Mo · 2017 · Biomaterials Science
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