Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

Walczak, Henning, Miller, Robert E., Ariail, Kiley, Gliniak, Brian, Griffith, Thomas S., Kubin, Marek, Chin, Wilson, Jones, Jon +8 more·1999·Nature Medicine

Cited by (1,003)

Items 501–600 of 1,003

  1. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines
    Shashirekha Shetty, J. Brown Gladden, Elizabeth S. Henson, Xiaojie Hu, Jacylyn Villanueva, Neil Haney, Spencer Bruce Gibson · 2002 · APOPTOSIS
  2. Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells.
    Shi‐Yong Sun, Ping Yue, Waun Ki Hong, Reuben Lotan · 2000 · PubMed
  3. Tumor Associated Macrophages Protect Colon Cancer Cells from TRAIL-Induced Apoptosis through IL-1β- Dependent Stabilization of Snail in Tumor Cells
    Pawan Kaler, Vincent P. Galea, Leonard H. Augenlicht, Lidija Klampfer · 2010 · PLoS ONE
  4. Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized
    Christopher C. Valley, Andrew K. Lewis, Deepti J. Mudaliar, Jason D. Perlmutter, Anthony R. Braun, Christine B. Karim, David Dale Thomas, Jonathan Robert Brody, Jonathan N. Sachs · 2012 · Journal of Biological Chemistry
  5. Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer
    Fumiaki Ozawa, Helmut Friess, Jorg H. Kleeff, Zhongwei Xu, A. Zimmermann, M. Saeed Sheikh, Markus Wolfgang Büchler · 2001 · Cancer Letters
  6. Cholestasis Increases Tumor Necrosis Factor-Related Apoptotis-Inducing Ligand (TRAIL)-R2/DR5 Expression and Sensitizes the Liver to TRAIL-Mediated Cytotoxicity
    Hajime Higuchi, Steven F. Bronk, Makiko Taniai, Ali E. Canbay, Gregory James Gores · 2002 · Journal of Pharmacology and Experimental Therapeutics
  7. Evidence for a Role of TNF-Related Apoptosis-Inducing Ligand (TRAIL) in the Anemia of Myelodysplastic Syndromes
    Diana Campioni, Paola Secchiero, Federica Corallini, Elisabetta Melloni, Silvano Capitani, Francesco Lanza, Giorgio Zauli · 2005 · American Journal Of Pathology
  8. Cell death in drug-induced liver injury
    Andrea Iorga, Lily Dara · 2019 · Advances in pharmacology
  9. Relative resistance of fresh isolates of melanoma to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.
    Tuong Nguyen, Xu Dong Zhang, Peter Hersey · 2001 · PubMed
  10. Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis
    Patrizia Marini, A. Schmid, Verena Jendrossek, Heidrun Faltin, Peter T. Daniel, Wilfried Budach, Claus Belka · 2005 · BMC Cancer
  11. TRAIL Gene Therapy: From Preclinical Development to Clinical Application
    Thomas S. Griffith, Brittany Stokes, Tamara A. Kucaba, James K. Earel, Rebecca L. VanOosten, Erik L. Brincks, Lyse A. Norian · 2009 · Current Gene Therapy
  12. Apoptosis and the response to anticancer therapy
    Benjamin M. F. Mow, April L. Blajeski, Joya Chandra, Scott H. Kaufmann · 2001 · Current Opinion in Oncology
  13. Mesenchymal Stem Cells as a Novel Carrier for Targeted Delivery of Gene in Cancer Therapy Based on Nonviral Transfection
    Yulan Hu, Bin Huang, Tianyuan Zhang, Pei‐Hong Miao, Guping Tang, Yasuhiko Tabata, Jianqing Gao · 2012 · Molecular Pharmaceutics
  14. Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo
    Haipeng Liu, Danmei Su, Jinlong Zhang, Shuai‐Shuai Ge, Youwei Li, Fei Wang, Michel Gravel, Anne Roulston, Song Qin, Wei Min Xu et al. · 2017 · Scientific Reports
  15. Target Cell–Restricted Apoptosis Induction of Acute Leukemic T Cells by a Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Protein with Specificity for Human CD7
    Edwin Bremer, Douwe Freerk Samplonius, Matthias Peipp, Linda van Genne, Bart‐Jan Kroesen, Georg H. Fey, Martin Gramatzki, Lou F. M. H. de Leij, Wijnand Helfrich · 2005 · Cancer Research
  16. Nanoparticle‐Mediated Target Delivery of TRAIL as Gene Therapy for Glioblastoma
    Kui Wang, Forrest M. Kievit, Mike Jeon, John R. Silber, Richard G. Ellenbogen, Miqin Zhang · 2015 · Advanced Healthcare Materials
  17. TNF Superfamily: A Growing Saga of Kidney Injury Modulators
    María Dolores Sánchez-Niño, Alberto Benito‐Martín, Sara Gonçalves, Ana Belen Sanz, Alvaro Conrado Ucero, María Concepción Izquierdo, Adrian Mario Ramos, Sergio Berzal, Rafael Selgas, Marta Ruiz‐Ortega et al. · 2010 · Mediators of Inflammation
  18. Cyclooxygenase-2 Inhibition Sensitizes Human Colon Carcinoma Cells to TRAIL-Induced Apoptosis through Clustering of DR5 and Concentrating Death-Inducing Signaling Complex Components into Ceramide-Enriched Caveolae
    Sophie Martin, Darren C. Phillips, Kinga Székely Szücs, Lynda Elghazi, Fabienne Desmots, Janet A. Houghton · 2005 · Cancer Research
  19. Inducible Release of TRAIL Fusion Proteins from a Proapoptotic Form for Tumor Therapy
    Khalid Shah, Ching‐Hsuan Tung, Katherine S. Yang, Ralph Weissleder, Xandra O. Breakefield · 2004 · Cancer Research
  20. Type I and type II reactions in TRAIL-induced apoptosis – results from dose–response studies
    Justine Rudner, Verena Jendrossek, Kirsten Lauber, Peter T. Daniel, Sebastian Wesselborg, Claus Belka · 2004 · Oncogene
  21. Wogonin and Related Natural Flavones Overcome Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein Resistance of Tumors by Down-regulation of c-FLIP Protein and Up-regulation of TRAIL Receptor 2 Expression
    Jie Ding, Gernot Polier, Rebecca Köhler, Marco Giaisi, Peter H. Krammer, Min Li‐Weber · 2011 · Journal of Biological Chemistry
  22. The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells
    Mano Horinaka, Tatsushi Yoshida, Takumi Shiraishi, Susumu Nakata, Miki Wakada, Ryoko Nakanishi, Hoyoku Nishino, Toshiyuki Sakai · 2005 · Biochemical and Biophysical Research Communications
  23. Target cell‐restricted and ‐enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma‐associated antigen EGP2
    Edwin Bremer, Jos M. A. Kuijlen, Douwe Freerk Samplonius, Henning Walczak, Lou de Leij, Wijnand Helfrich · 2003 · International Journal of Cancer
  24. Atypical Teratoid/Rhabdoid Tumors of the Central Nervous System
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  25. Hepatitis B virus core protein inhibits TRAIL-induced apoptosis of hepatocytes by blocking DR5 expression
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  26. Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1
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  27. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27Kip1 and control of cyclin D1 expression
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  28. ABT-737 Induces Expression of the Death Receptor 5 and Sensitizes Human Cancer Cells to TRAIL-induced Apoptosis
    Jin Hyang Song, Karthikeyan Kandasamy, Andrew S. Kraft · 2008 · Journal of Biological Chemistry
  29. Surface-Enhanced Raman Scattering-Based Sensing In Vitro: Facile and Label-Free Detection of Apoptotic Cells at the Single-Cell Level
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  30. Is TRAIL hepatotoxic?
    Gregory Gores, Scott H. Kaufmann · 2001 · Hepatology
  31. Genetic Modification of T Lymphocytes for Adoptive Immunotherapy
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  32. HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP)
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  33. Novel Apoptosis-Inducing Agents for the Treatment of Cancer, a New Arsenal in the Toolbox
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  34. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis
    S-A Quast, Anja Berger, Jürgen Eberle · 2013 · Cell Death and Disease
  35. Targeting cyclooxygenase‐2 for prevention and therapy of colorectal cancer
    Frank A. Sinicrope · 2006 · Molecular Carcinogenesis
  36. Role of Cell-Death Ligand-Receptor System of Granulosa Cells in Selective Follicular Atresia in Porcine Ovary
    Naoko Inoue, Fuko Matsuda, Yasufumi Goto, Noboru MANABE · 2011 · Journal of Reproduction and Development
  37. TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome–positive leukemia cells
    Kanako Uno, Takeshi Inukai, Nobuhiko Kayagaki, Kumiko Goi, Hiroki Sato, Atsushi Nemoto, Kazuya Takahashi, Keiko Kagami, Noriko Yamaguchi, Hideo Yagita∥ et al. · 2003 · Blood
  38. Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells
    Seok‐Hyun Kim, Kunhong Kim, Jae Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, Wafik S. El‐Deiry · 2004 · Journal of Biological Chemistry
  39. Suppression of Tumor Growth Following Intralesional Therapy with TRAIL Recombinant Adenovirus
    Thomas S. Griffith, Elizabeth L. Broghammer · 2001 · Molecular Therapy
  40. Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors
    Bryant G. Darnay, Bharat B Aggarwal · 1999 · Annals of the Rheumatic Diseases
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    Schleich, K, Buchbinder, J H, Pietkiewicz, S, Kähne, T, Warnken, U, Öztürk, S, Schnölzer, M, Naumann, M, Krammer, P H, Lavrik, I N · 2016 · Cell Death & Differentiation
  42. Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-κB but is related to downregulation of initiator caspases and DR4
    Bahtier M. Kurbanov, Lothar F. Fecker, Christoph C. Geilen, Wolfram Sterry, Jürgen Eberle · 2006 · Oncogene
  43. TRAIL and doxorubicin combination enhances anti-glioblastoma effect based on passive tumor targeting of liposomes
    Liangran Guo, Li Fan, Zhiqing Pang, Jinfen Ren, Yulong Ren, Jingwei Li, Jie Chen, Ziyi Wen, Xinguo Jiang · 2011 · Journal of Controlled Release
  44. Serum bioactive lysophospholipids prevent TRAIL-induced apoptosis via PI3K/Akt-dependent cFLIP expression and Bad phosphorylation
    Y-C Kang, K-M Kim, KS Lee, Seung Namkoong, SJ Lee, J-A Han, D Jeoung, Kwon‐Soo Ha, Y-G Kwon, Y-M Kim · 2004 · Cell Death and Differentiation
  45. Treating Metastatic Solid Tumors With Bortezomib and a Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor Agonist Antibody
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  46. Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction
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  47. Nitric oxide-induced apoptosis in tumor cells
    Victor Umansky, Volker Schirrmacher · 2001 · Advances in cancer research
  48. Tumor necrosis factor–related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway
    Paola Secchiero, Arianna Gonelli, Prisco Mirandola, Elisabetta Melloni, Loris Zamai, Claudio Celeghini, Daniela Milani, Giorgio Zauli · 2002 · Blood
  49. Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2
    Eiji Mori, M Thomas, Kazuhiro Motoki, K Nakazawa, T. Tahara, Kazuma Tomizuka, I. Ishida, Shun Kataoka · 2003 · Cell Death and Differentiation
  50. Selective Inhibition of IκB Kinase Sensitizes Mantle Cell Lymphoma B Cells to TRAIL by Decreasing Cellular FLIP Level
    Gaël Roué, Patricia Pérez‐Galán, Mònica López‐Guerra, Neus Villamor, Elı́as Campo, Dolors Colomer · 2007 · The Journal of Immunology
  51. Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer
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  52. Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes.
    Sorin Armeanu, Ulrich M. Lauer, Irina Smirnow, Martin Schenk, Thomas S. Weiß, Michael Gregor, Michael Bitzer · 2003 · PubMed
  53. Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway
    Clarissa von Haefen, Bernhard F. Gillissen, Philipp Hemmati, Jana Wendt, Dilek Güner, Alicja Mrozek, Claus Belka, Bernd Dörken, Peter T. Daniel · 2004 · Oncogene
  54. IFN-?induces cell death in human hepatoma cells through a trail/death receptor-mediated apoptotic pathway
    Eui‐Cheol Shin, Ju Mi Ahn, Chul Hoon Kim, Youjeong Choi, Young Soo Ahn, Hoguen Kim, Se‐Jong Kim, Jeon Han Park · 2001 · International Journal of Cancer
  55. Akkermansia muciniphila Aspartic Protease Amuc_1434* Inhibits Human Colorectal Cancer LS174T Cell Viability via TRAIL-Mediated Apoptosis Pathway
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  56. Engineering Exosomes Endowed with Targeted Delivery of Triptolide for Malignant Melanoma Therapy
    Liangdi Jiang, Yongwei Gu, Yue Du, Xiaomeng Tang, Xin Wu, Jiyong Liu · 2021 · ACS Applied Materials & Interfaces
  57. Recent Advances in CAR-Based Solid Tumor Immunotherapy
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  59. Direct Binding of Fas-associated Death Domain (FADD) to the Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor DR5 Is Regulated by the Death Effector Domain of FADD
    Lance R. Thomas, Adrianna L. Henson, John C. Reed, Freddie R. Salsbury, Andrew M. Thorburn · 2004 · Journal of Biological Chemistry
  60. Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: Involvement of ROS-dependent ER-stress
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  61. HIV Type 1-Infected Dendritic Cells Induce Apoptotic Death in Infected and Uninfected Primary CD4 T Lymphocytes
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  68. Pancreatic Adenocarcinoma Cell Lines Show Variable Susceptibility to TRAIL-Mediated Cell Death
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