Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

Walczak, Henning, Miller, Robert E., Ariail, Kiley, Gliniak, Brian, Griffith, Thomas S., Kubin, Marek, Chin, Wilson, Jones, Jon +8 more·1999·Nature Medicine

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Items 901–1,000 of 1,003

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  6. Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line
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  7. Bifidobacterium longum as a delivery system of TRAIL and endostatin cooperates with chemotherapeutic drugs to inhibit hypoxic tumor growth
    Boqiang Hu, L Kou, Chao Li, L-P Zhu, Y-R Fan, Z-W Wu, J-J Wang, G-X Xu · 2009 · Cancer Gene Therapy
  8. Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors
    Toshihiko Doi, Haruyasu Murakami, Atsushi Ohtsu, Nozomu Fuse, Takayuki Yoshino, Nobuyuki Yamamoto, Narikazu Boku, Yusuke Onozawa, C-P. Hsu, Kevin S. Gorski et al. · 2010 · Cancer Chemotherapy and Pharmacology
  9. TRAIL/TRAIL‐R in hematologic malignancies
    Ugo Testa · 2010 · Journal of Cellular Biochemistry
  10. Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effect
    Ja Young Seol, Kyungho Park, Chang‐Il Hwang, Woong‐Yang Park, Chul‐Gyu Yoo, Young Whan Kim, Sung Koo Han, Young‐Soo Shim, Choon‐Taek Lee · 2003 · Cancer Gene Therapy
  11. Stem cells are resistant to TRAIL receptor‐mediated apoptosis
    Éva Szegezdi, Aoife O’Reilly, Davy Yeung, Reaz Vawda, Deanna L. Taylor, Mary J. Murphy, Afshin Samali A, Huseyin Mehmet · 2008 · Journal of Cellular and Molecular Medicine
  12. Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response
    Lihua Chen, Chen Chen Jiang, Kelly A. Avery‐Kiejda, Yufang Wang, Rick Francis Thorne, Xu Dong Zhang, Peter Hersey · 2007 · Carcinogenesis
  13. Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3
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  14. Non-Hodgkin’s B-cell lymphoma: Advances in molecular strategies targeting drug resistance
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  15. Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy
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  16. Oxidative stress-driven DR5 upregulation restores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles in colorectal cancer
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  17. Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells
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  18. Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand and Its Receptor Expression and the Pathway of Apoptosis in Human Pancreatic Cancer
    Kennichi Satoh, Kenzo Kaneko, Morihisa Hirota, Atsushi Masamune, Akihiko Satoh, Tooru Shimosegawa · 2001 · Pancreas
  19. Dexamethasone inhibits TRAIL-induced apoptosis of thyroid cancer cells via Bcl-xL induction
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  20. cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis
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  21. The involvement of oxidative stress in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in HeLa cells
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  22. Novel biological therapies for the treatment of multiple myeloma
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  23. A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents
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  24. Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors
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  27. Tumour necrosis factor‐related apoptosis‐inducing ligand (TRAIL)‐induced chemokine release in both TRAIL‐resistant and TRAIL‐sensitive cells via nuclear factor kappa B
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  29. Overcoming Acquired Resistance to TRAIL by Chemotherapeutic Agents and Calpain Inhibitor I through Distinct Mechanisms
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  33. Delphinidin sensitizes prostate cancer cells to TRAIL-induced apoptosis, by inducing DR5 and causing caspase-mediated HDAC3 cleavage
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  36. Blockade of Death Receptor-Mediated Pathways Early in the Signaling Cascade Coincides with Distinct Apoptosis Resistance in Cutaneous T-Cell Lymphoma Cells
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  39. Trail Receptor-Targeted Therapy
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  41. Mesenchymal Progenitors Expressing<scp>TRAIL</scp>Induce Apoptosis in Sarcomas
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  42. Detection of soluble TRAIL in HBV infected patients and its clinical implications
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  43. Roles of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling Pathway in Granulosa Cell Apoptosis During Atresia in Pig Ovaries
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  45. Suppression of orthotopically implanted hepatocarcinoma in mice by umbilical cord-derived mesenchymal stem cells with sTRAIL gene expression driven by AFP promoter
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  46. Increased Apoptosis Induction in Hepatocellular Carcinoma by a Novel Tumor-Targeted TRAIL Fusion Protein Combined With Bortezomib
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  47. Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway
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  48. The role of XIAP in resistance to TNF-related apoptosis-inducing ligand (TRAIL) in Leukemia
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  49. Death Receptor Ligands, in Particular TRAIL, to Overcome Drug Resistance
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  50. Enhanced Metastasis Suppression by Targeting TRAIL Receptor 2 in a Murine Model of Triple-Negative Breast Cancer
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  51. Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model
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  53. CELL DEATH AT THE MILLENNIUM
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  57. Death receptor-4 (DR4) expression is regulated by transcription factor NF-κB in response to etoposide treatment
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  58. DAPK2 is a novel modulator of TRAIL-induced apoptosis
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  59. Combined modality therapy with TRAIL or agonistic death receptor antibodies
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