Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

Walczak, Henning, Miller, Robert E., Ariail, Kiley, Gliniak, Brian, Griffith, Thomas S., Kubin, Marek, Chin, Wilson, Jones, Jon +8 more·1999·Nature Medicine

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Items 601–700 of 1,003

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  2. Sensitization of TRAIL-Induced Cell Death by 20(S)-Ginsenoside Rg3 via CHOP-Mediated DR5 Upregulation in Human Hepatocellular Carcinoma Cells
    Ju‐Yeon Lee, Kyung Hee Jung, Michael J. Morgan, Yi-Rae Kang, Hee‐Seung Lee, Gi-Bang Koo, Soon‐Sun Hong, Sung Won Kwon, You Sun Kim · 2012 · Molecular Cancer Therapeutics
  3. Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells
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    B. Nickoloff, Jian-Zhong Qin, V. Chaturvedi, P. Bacon, Jeffrey R. Panella, M. Denning · 2002 · Journal of Investigative Dermatology Symposium Proceedings
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    Sang‐Youel Park, Timothy R. Billiar, Dai‐Wu Seol · 2002 · Biochemical and Biophysical Research Communications
  6. Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D
    A Olsson, T Diaz, Miguel Aguilar‐Santelises, Anders Österborg, Fredrik Celsing, Mikael Jondal, LM Osorio · 2001 · Leukemia
  7. Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis
    Kallenberger, Stefan M., Beaudouin, Joël, Claus, Juliane, Fischer, Carmen, Sorger, Peter K., Legewie, Stefan, Eils, Roland · 2014 · Science Signaling
  8. Emerging applications of bacteria as antitumor agents
    Vipin Chandra Kalia, Sanjay K. S. Patel, Byung‐Kwan Cho, Thomas Keith Wood, Jung-Kul Lee · 2021 · Seminars in Cancer Biology
  9. Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL
    Norman Kock, Randa Kasmieh, Ralph Weissleder, Khalid Shah · 2007 · Neoplasia
  10. Tumor necrosis factor family ligand–receptor binding
    Gongyi Zhang · 2004 · Current Opinion in Structural Biology
  11. ROS and CHOP Are Critical for Dibenzylideneacetone to Sensitize Tumor Cells to TRAIL through Induction of Death Receptors and Downregulation of Cell Survival Proteins
    Sahdeo Prasad, Vivek Ramshankar Yadav, Jayaraj Ravindran, Bharat Bhushan Aggarwal · 2010 · Cancer Research · Retracted
  12. Suramin inhibits death receptor–induced apoptosis in vitro and fulminant apoptotic liver damage in mice
    Sören T. Eichhorst, Andreas Krueger, Susanne Sebens Müerköster, Stefanie C. Fas, Alexander Golks, Uwe Gruetzner, Louise Schubert, Christine Opelz, M Bilzer, Alexander L. Gerbes et al. · 2004 · Nature Medicine
  13. Functional expression of TWEAK in human hepatocellular carcinoma: possible implication in cell proliferation and tumor angiogenesis
    Tomoyuki Kawakita, Katsuya Shiraki, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Naoyuki Enokimura, Norihiko Yamamoto, Hiroshi Okano, Kazushi Sugimoto, Kazumoto Murata et al. · 2004 · Biochemical and Biophysical Research Communications
  14. Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells
    Xiao Zhang, Xiang Zhang, Shijie Hu, Minhua Zheng, Jie Zhang, Jianhui Zhao, Xiaofang Zhang, Bo Yan, Lintao Jia, Jing Zhao et al. · 2017 · Nucleic Acids Research
  15. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
    Santiago Grijalvo, Adele Alagia, Andreia F. Jorge, Ramón Eritja · 2018 · Genes
  16. c-E10 Is a Caspase-recruiting Domain-containing Protein That Interacts with Components of Death Receptors Signaling Pathway and Activates Nuclear Factor-κB
    Antonio Costanzo, Chantal Guiet, Pasquale Vito · 1999 · Journal of Biological Chemistry
  17. Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand and Chemotherapy Cooperate to Induce Apoptosis in Mesothelioma Cell Lines
    Weihong Liu, Ethan E. Bodle, Jessica Y. Chen, Mingxing Gao, GD Rosen, V. Courtney Broaddus · 2001 · American Journal of Respiratory Cell and Molecular Biology
  18. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells
    C.-Y. Jin, Dong‐Oh Moon, J.-D. Lee, M.-S. Heo, Yung Hyun Choi, C.-M. Lee, Y.-M. Park, Gi‐Young Kim · 2006 · Carcinogenesis
  19. Emerging roles of hypoxia‐inducible factors and reactive oxygen species in cancer and pluripotent stem cells
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  20. Changes in apoptosis during the development of colorectal cancer: a systematic review of the literature
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  21. Improved Antitumor Activity and Tumor Targeting of NH2-Terminal–Specific PEGylated Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand
    Su Young Chae, Tae Hyung Kim, Kyeongsoon Park, Cheng‐Hao Jin, Sohee Son, Seulki Lee, Yu Seok Youn, Kwangmeyung Kim, Dong‐Gyu Jo, Ick Chan Kwon et al. · 2010 · Molecular Cancer Therapeutics
  22. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells
    Susan K. H. Gillespie, Jodie M. Borrow, Xu Dong Zhang, Peter Hersey · 2006 · APOPTOSIS
  23. Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancer xenografts
    Ahmed M El-Zawahry, John C. McKillop, Christina Voelkel‐Johnson · 2005 · BMC Cancer
  24. Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells
    Katharina Clodi, Doris Wimmer, Yang Li, Raymond G. Goodwin, Ulrich Jaeger, Georg Mann, H. Gadner, Anas Younes · 2000 · British Journal of Haematology
  25. Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma
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  26. Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways
    Marianne van Dijk, Anna McCormick, Tamas Sessler, Afshin Samali A, Éva Szegezdi · 2013 · Cell Death and Disease
  27. TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells
    Mark H. Tuthill, Antonella Montinaro, Julia Zinngrebe, Katharina Prieske, Peter Dráber, Silvia Prieske, Thomas E. Newsom-Davis, Silvia von Karstedt, Jonathan D. Graves, Henning Walczak · 2014 · Oncogene
  28. Efficient TRAIL-R1/DR4-Mediated Apoptosis in Melanoma Cells by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
    Bahtier M. Kurbanov, Christoph C. Geilen, Lothar F. Fecker, Constantin E. Orfanos, Jürgen Eberle · 2005 · Journal of Investigative Dermatology
  29. Activation of Wnt/β-Catenin Signaling Increases Apoptosis in Melanoma Cells Treated with Trail
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  30. Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis
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  31. Tumor-Infiltrating CD4+ T Lymphocytes Express APO2 Ligand (APO2L)/TRAIL upon Specific Stimulation with Autologous Lung Carcinoma Cells: Role of IFN-α on APO2L/TRAIL Expression and -Mediated Cytotoxicity
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  32. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
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  33. Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance
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  34. Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL
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  35. TNF-Related Apoptosis-Inducing Ligand: Non-Apoptotic Signalling
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  36. Clinical implications of the tumor necrosis factor family in benign and malignant hematologic disorders
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  38. The C-terminal Tails of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas Receptors Have Opposing Functions in Fas-associated Death Domain (FADD) Recruitment and Can Regulate Agonist-specific Mechanisms of Receptor Activation
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  42. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-κB activity
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  48. Aspirin Sensitizes Cancer Cells to TRAIL–Induced Apoptosis by Reducing Survivin Levels
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  49. Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL
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  50. TRAIL-death receptor endocytosis and apoptosis are selectively regulated by dynamin-1 activation
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  51. Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin
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  53. CASC2/miR-24/miR-221 modulates the TRAIL resistance of hepatocellular carcinoma cell through caspase-8/caspase-3
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  55. The ‘kiss of death’ by dendritic cells to cancer cells
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  57. Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature
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  58. PRMT5, a Novel TRAIL Receptor-Binding Protein, Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κB Activation
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