Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
Liberatore, Gabriel T., Jackson-Lewis, Vernice, Vukosavic, Slobodanka, Mandir, Allen S., Vila, Miquel, McAuliffe, W. Geoffrey, Dawson, Valina L., Dawson, Ted M. +1 more·1999·Nature Medicine
DOI 10.1038/70978
Cited by (1,000)
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- IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitisAdam Ian Kaplin · 2005 · Journal of Clinical Investigation
- The acute and the long‐term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activationMahmoud M. Iravani, Clement C. M. Leung, Mona Sadeghian, Claire O. Haddon, Sarah Rose, Peter G. Jenner · 2005 · European Journal of Neuroscience
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- The Endotoxin-Induced Neuroinflammation Model of Parkinson's DiseaseKemal Uğur Tüfekçi, Şermin Genç, Kürşad Genç · 2011 · Parkinson s Disease
- Oxidative stress regulated genes in nigral dopaminergic neuronal cells: correlation with the known pathology in Parkinson’s diseaseMyung Sik Yoo, Hong Sung Chun, Jessica J. Son, Lorraine A. DeGiorgio, Dae Joon Kim, Chu Peng, Jin H. Son · 2003 · Molecular Brain Research
- Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregatesShigeki Arawaka, Hiroyasu Sato, Asuka Sasaki, Shingo Koyama, Takeo Kato · 2017 · Acta Neuropathologica Communications
- Blood–Brain Barrier Permeable Photoacoustic Probe for High-Resolution Imaging of Nitric Oxide in the Living Mouse BrainZhiyong Jiang, Zhaolun Liang, Yijing Cui, Changli Zhang, Jing Wang, Hong Wang, Tianzhu Wang, Yuncong Chen, Weijiang He, Zhipeng Liu et al. · 2023 · Journal of the American Chemical Society
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- Nitrated α-Synuclein Induces the Loss of Dopaminergic Neurons in the Substantia Nigra of RatsZhongwang Yu, Xiaohui Xu, Zhenghua Xiang, Jianfeng Zhou, Zhaohuan Zhang, Chun Hu, Cheng He · 2010 · PLoS ONE
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- Delayed peripheral Nerve Degeneration, Regeneration, and pain in Mice Lacking Inducible Nitric Oxide SynthaseDan Levy, Paul Kubes, Douglas William Zochodne · 2001 · Journal of Neuropathology & Experimental Neurology
- Systemic LPS administration induces brain inflammation but not dopaminergic neuronal death in the substantia nigraHey‐Kyeong Jeong, Ilo Jou, Eun-hye Joe · 2010 · Experimental & Molecular Medicine
- Mitochondrial Dysfunction and Oxidative Stress in Parkinson’s DiseaseIsaac G. Onyango · 2007 · Neurochemical Research
- Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease.C. Depboylu, S. Stricker, Jean-Pierre Ghobril, W. Oertel, Josef Priller, G. Höglinger · 2012 · Experimental Neurology