Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
Liberatore, Gabriel T., Jackson-Lewis, Vernice, Vukosavic, Slobodanka, Mandir, Allen S., Vila, Miquel, McAuliffe, W. Geoffrey, Dawson, Valina L., Dawson, Ted M. +1 more·1999·Nature Medicine
DOI 10.1038/70978
Cited by (1,000)
Items 501–600 of 1,000
- Manganese-Induced NF-κB Activation and Nitrosative Stress Is Decreased by Estrogen in Juvenile MiceJulie A. Moreno, Karin M. Streifel, Kelly A. Sullivan, William H. Hanneman, Ronald B. Tjalkens · 2011 · Toxicological Sciences
- Neuroprotective Role of Atractylenolide-I in an In Vitro and In Vivo Model of Parkinson’s DiseaseSandeep Vasant More, Dong‐Kug Choi · 2017 · Nutrients
- Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson’s Disease via Lysophosphatidic Acid ReceptorsJong Hee Choi, Minhee Jang, Seikwan Oh, Seung-Yeol Nah, Ik‐Hyun Cho · 2018 · Frontiers in Pharmacology
- Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitroMustafa Taleb Ardah, Madiha Mohieldin Merghani, M. Emdadul Haque · 2019 · Neurochemistry International
- L ‐3‐hydroxyacyl‐CoA dehydrogenase II protects in a model of Parkinson's diseaseKim Tieu, Céline Perier, Miquel Vila, Casper S. Caspersen, Hui‐Ping Zhang, Peter Teismann, Vernice R. Jackson-Lewis, David M. Stern, Shi Du Yan, Serge Przedborski · 2004 · Annals of Neurology
- Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activationLiyan Hou, Cong Zhang, Ke Wang, Xiaofang Liu, Hongwei Wang, Yuning Che, Fuqiang Sun, Xueying Zhou, Xiulan Zhao, Qingshan Wang · 2017 · Toxicology
- Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase‐2 via CD40: Relevance to Parkinson's diseaseTatsusada Okuno, Yuji Nakatsuji, Atsushi Kumanogoh, M. Moriya, Hiroshi Ichinose, Hisae Sumi, Harutoshi Fujimura, Hitoshi Kikutani, Saburo Sakoda · 2005 · Journal of Neuroscience Research
- Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficent miceGerecke, Kim M., Jiao, Yun, Pagala, Viswajeeth, Smeyne, Richard J. · 2012 · PLoS ONE
- Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the ratBarthwal, M.K., Srivastava, N., Dikshit, M. · 2001 · Redox Report
- Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axisQiang Ma, Jin-Lan Tian, Yao Lou, Ran Guo, Xiao-Ru Ma, Jianbin Wu, Jing Yang, Bing-Jie Tang, Shun Li, Mengsheng S. Qiu et al. · 2025 · Cell Reports
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathwayYuanye Li, Gang Chen, Jianya Zhao, Xiaoke Nie, Chunhua Wan, Jiao Liu, Zhiqing Duan, Guangfei Xu · 2013 · Toxicology
- A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's diseaseChi‐Jing Choong, Tsutomu Sasaki, Hideki Hayakawa, Toru Yasuda, Kousuke Baba, Yoshiyuki Hirata, Shinichi Uesato, Hideki Mochizuki · 2015 · Neurobiology of Aging
- Ratiometric SERS imaging and selective biosensing of nitric oxide in live cells based on trisoctahedral gold nanostructuresQiao Xu, Wei Liu, Li Li, Feng Zhou, Jian Er Zhou, Yang Tian · 2017 · Chemical Communications
- GYY4137, an H2S Slow-Releasing Donor, Prevents Nitrative Stress and α-Synuclein Nitration in an MPTP Mouse Model of Parkinson’s DiseaseXiao‐Ou Hou, Yuqing Yuan, Yulan Sheng, Baoshi Yuan, Yali Wang, Jiyue Zheng, Chun‐Feng Liu, Xiaohu Zhang, Li‐Fang Hu · 2017 · Frontiers in Pharmacology
- S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfoldingTomohiro Nakamura, Stuart A. Lipton · 2007 · Cell Death and Differentiation
- Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013Tullia Maraldi, David Vauzour, Cristina Angeloni · 2014 · Oxidative Medicine and Cellular Longevity
- Therapeutically targeting astrocytes with stem and progenitor cell transplantation following traumatic spinal cord injuryAditi Falnikar, Ke Li, Angelo C. Lepore · 2014 · Brain Research
- Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 ratsJang-Won Lee, Vı́ctor Tapias, Roberto Di Maio, J. Timothy Greenamyre, Jason R. Cannon · 2014 · Neurobiology of Aging
- Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in miceHironori Yokoyama, Sho Takagi, Yu Watanabe, Hiroyuki Kato, Tsutomu Araki · 2008 · Journal of Neural Transmission
- Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic miceStephen J. Crocker, Peter Liston, Hymie Anisman, Christopher J. Lee, Patrice D. Smith, N Earl, Charlie S. Thompson, David S. Park, Robert G. Korneluk, George S. Robertson · 2003 · Neurobiology of Disease
- Strain‐dependent susceptibility to MPTP and MPP‐induced Parkinsonism is determined by gliaMichelle Smeyne, Olga G. Goloubeva, Richard Jay Smeyne · 2001 · Glia
- The Neuroprotective Effect of Fisetin in the MPTP Model of Parkinson's DiseaseMital Y. Patel, Hirenkumar Panchal, Othman Ghribi, Kenza E. Benzeroual · 2012 · Journal of Parkinson s Disease
- Mapping and kinetics of microglia/neuron cell-to-cell contacts in the 6-OHDA murine model of Parkinson's diseaseAngélique Virgone‐Carlotta, Josselin Uhlrich, Muhammad Numan Akram, Denis Ressnikoff, Fabrice Chrétien, Chantal Domenget, Romain Kroum Gherardi, Geneviève Despars, Pierre Jurdic, Jérôme Honnorat et al. · 2013 · Glia
- Exacerbation of Dopaminergic Terminal Damage in a Mouse Model of Parkinson’s Disease by the G-Protein-Coupled Receptor Protease-Activated Receptor 1Cecily E. Hamill, William Michael Caudle, Jason R. Richardson, Hongjie Yuan, Kurt D. Pennell, James G. Greene, Gary Wright Miller, Stephen F. Traynelis · 2007 · Molecular Pharmacology
- Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stress: In vivo and in vitro evidenceCarmen Avagliano, Roberto Russo, Carmen De Caro, Claudia Cristiano, Giovanna La Rana, Giuseppe Piegari, Orlando Paciello, Rita Citraro, Emilio Russo, Giovambattista De Sarro et al. · 2016 · Pharmacological Research
- Role of Molecular Hydrogen in Ageing and Ageing‐Related DiseasesZhiling Fu, Jin Zhang, Yan Zhang · 2022 · Oxidative Medicine and Cellular Longevity
- NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian MiceMarina S. Hernandes, Cecília C. Café-Mendes, Luiz Roberto Britto · 2013 · Oxidative Medicine and Cellular Longevity
- Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy?Anna Rosa Carta, Augusta Pisanu, Ezio Carboni · 2011 · Parkinson s Disease
- Novel Para-Phenyl Substituted Diindolylmethanes Protect Against MPTP Neurotoxicity and Suppress Glial Activation in a Mouse Model of Parkinson’s DiseaseBriana R. De Miranda, Katriana A. Popichak, Sean L. Hammond, James Adam Miller, Stephen H Safe, Ronald B. Tjalkens · 2014 · Toxicological Sciences
- Spatial memory deficits and oxidative stress damage following exposure to lipopolysaccharide in a rodent model of Parkinson's diseaseLucian Hriţcu, Alin Stelian Ciobica, Marius Ștefan, Marius Mihăşan, Lavinia Palamiuc, Toshitaka Nabeshima · 2011 · Neuroscience Research
- Neurotrophic and neurotoxic effects of nitric oxide on fetal midbrain culturesSantiago Canals, Marı́a José Casarejos, Eulalia Rodríguez‐Martín, Sonsoles de Bernardo, M. A. Mena · 2001 · Journal of Neurochemistry
- Developing electrochemical sensor for point-of-care diagnostics of oxidative stress marker using imprinted bimetallic Fe/Pd nanoparticleEkta Roy, Santanu Patra, Rashmi Madhuri, Prashant K. Sharma · 2014 · Talanta
- Neuroprotective and Neurotherapeutic Effects of Tetrahedral Framework Nucleic Acids on Parkinson’s Disease in VitroWeitong Cui, Yuxi Zhan, Xiaoru Shao, Wei Fu, Dexuan Xiao, Junyao Zhu, Xin Qin, Tianyi Zhang, Mei Zhang, Yi Zhou et al. · 2019 · ACS Applied Materials & Interfaces
- Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson’s Disease: An In Silico and In Vivo StudyBabita Singh, Shivani Pandey, Mohammad Rumman, Shashank Kumar, Prem Prakash Kushwaha, Rajesh Verma, Abbas Ali Mahdi · 2021 · Frontiers in Pharmacology
- The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicityMélissa Côté, Janelle Drouin‐Ouellet, Francesca Cicchetti, Denis Soulet · 2011 · Brain Behavior and Immunity
- Mangiferin Antagonizes Rotenone: Induced Apoptosis Through Attenuating Mitochondrial Dysfunction and Oxidative Stress in SK-N-SH Neuroblastoma CellsKavitha, Mani, Manivasagam, Thamilarasan, Essa, Musthafa Mohamed, Tamilselvam, Kuppusamy, Selvakumar, Govindasamy Pushpavathy, Karthikeyan, Subran, Thenmozhi, Justin Arokiasamy, Subash, Selvaraju · 2014 · Neurochemical Research
- Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson’s diseaseBalachandran Krishnamma Binukumar, Varsha Shukla, Niranjana D. Amin, Philip G. Grant, M. Bhaskar, Susan Skuntz, Joseph P. Steiner, Harish C. Pant · 2015 · Molecular Biology of the Cell
- Differential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingEirini Lionaki, Ilias Gkikas, Nektarios Tavernarakis · 2016 · Frontiers in Genetics
- Brain-derived neurotropic factor and GABAergic transmission in neurodegeneration and neuroregenerationMiyoung Yang, Changjong Moon, Jinwook Kim, Sueun Lee, Sohi Kang, Sung‐Ho Kim, Jong-Choon Kim · 2017 · Neural Regeneration Research
- Demethoxycurcumin, a natural derivative of curcumin abrogates rotenone-induced dopamine depletion and motor deficits by its antioxidative and anti-inflammatory properties in Parkinsonian ratsSrinivasagam Rajasankar, Muthu Ramkumar, Veerapan Venkatesh Gobi, Udaiyappan Janakiraman, Thamilarasan Manivasagam, Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Ranganathan Chidambaram, Saravana Babu Chidambaram, Gilles J. Guillemin · 2018 · Pharmacognosy Magazine
- The unlikely partnership between LRRK 2 and α‐synuclein in Parkinson's diseaseNoémie Cresto, Camille Gardier, Francesco Gubinelli, Marie‐Claude Gaillard, Géraldine Liot, West Andrew B, Emmanuel Brouillet · 2018 · European Journal of Neuroscience
- Serum antibodies from Parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expressionVictor C. Huber, Tapan Kumar Mondal, Stewart Alan Factor, Richard F. Seegal, David A. Lawrence · 2006 · Journal of Neuroinflammation
- A cytokine mixture of GM‐CSF and IL‐3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6‐OHDA)‐induced Parkinsonism of ratsMohammed Emamussalehin Choudhury, Kana Sugimoto, Madoka Kubo, Masahiro Nagai, Masahiro Nomoto, Hisaaki Takahashi, Hajime Yano, Junya Tanaka · 2011 · Brain and Behavior
- In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazoleBobby Thomas, Karuppagounder S. Saravanan, Kochupurackal P. Mohanakumar · 2007 · Neurochemistry International
- Nitric Oxide Donors Induce Neurotrophin-Like Survival Signaling and Protect Neurons against ApoptosisCarsten Culmsee, Norbert Gerling, Stefan Landshamer, Bianca Rickerts, Hans‐Jürgen Duchstein, Kazuo Umezawa, Susanne Klumpp, Josef Krieglstein · 2005 · Molecular Pharmacology
- Silibinin Attenuates MPP + -Induced Neurotoxicity in the Substantia Nigra In VivoUn Ju Jung, Min‐Tae Jeon, Myung‐Sook Choi, Sang Ryong Kim · 2014 · Journal of Medicinal Food
- Neuroprotection by Silencing iNOS Expression in a 6-OHDA Model of Parkinson’s DiseaseMin Li, Fu-rong Dai, Xiaoping Du, Qidong Yang, Yuxiang Chen · 2012 · Journal of Molecular Neuroscience
- Pathological consequences of inducible nitric oxide synthase expression in hippocampal slice culturesSophie Duport, John Garthwaite · 2005 · Neuroscience
- Involvement of dopaminergic neuronal cystatin C in neuronal injury‐induced microglial activation and neurotoxicityGarima Dutta, David S. Barber, Ping Zhang, Nicholas J. Doperalski, Bin Liu · 2012 · Journal of Neurochemistry
- Role of Nitric Oxide in Motor Control: Implications for Parkinson's Disease Pathophysiology and TreatmentElaine Del-Bel, Fernando E. Padovan‐Neto, Rita Raisman‐Vozari, Márcio Lazzarini · 2011 · Current Pharmaceutical Design
- Effect of Microglia Activation on Dopaminergic Neuronal Injury Induced by Manganese, and Its Possible MechanismMingchao Liu, Tongjian Cai, Fang Zhao, Gang Zheng, Qiang Wang, Yaoming Chen, Chuanshu Huang, Wenjing Luo, Jingyuan Chen · 2009 · Neurotoxicity Research
- Attenuation of MPTP/MPP+ toxicity in vivo and in vitro by an 18-mer peptide derived from prosaposinHuiling Gao, C. Li, Hiroaki Nabeka, Tetsuya Shimokawa, Shouichiro Saito, Zhan‐You Wang, Yaming Cao, Seiji Matsuda · 2013 · Neuroscience
- GPER activation is effective in protecting against inflammation-induced nigral dopaminergic loss and motor function impairmentJulieta Mendes‐Oliveira, Filipa Lopes Campos, Rita Alexandra Videira, Graça Baltazar · 2017 · Brain Behavior and Immunity
- Recombinant human granulocyte colony‐stimulating factor protects against MPTP‐induced dopaminergic cell death in mice by altering Bcl‐2/Bax expression levelsXuqing Cao, Hiroyuki Arai, Yong‐Ri Ren, Hideki Oizumi, Ning Zhang, Shiho Seike, Tsuyoshi Furuya, Toru Yasuda, Yoshikuni Mizuno, Hideki Mochizuki · 2006 · Journal of Neurochemistry
- Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAPAndis Klegeris, Patrick L. McGeer · 2003 · Journal of Leukocyte Biology
- Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6Rituraj Niranjan, Chandishwar Nath, Rakesh Shukla · 2012 · Free Radical Research
- 1H MRS identifies lactate rise in the striatum of MPTP‐treated C57BL/6 miceKeiko Koga, Atsushi Mori, Satoshi Ohashi, Naoki Kurihara, Hisashi Kitagawa, Makoto Ishikawa, Yasuhide Mitsumoto, Masami Nakai · 2006 · European Journal of Neuroscience
- Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In VivoHai‐Jing Zhong, Lijuan Liu, Cheong‐Meng Chong, Lihua Lu, Modi Wang, Daniel Shiu‐Hin Chan, Philip Wai Hong Chan, Simon Ming‐Yuen Lee, Dik‐Lung Ma, Chung‐Hang Leung · 2014 · PLoS ONE
- Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitroTeresa Iuvone, Giuseppe Esposito, Daniele De Filippis, Tiziana Bisogno, Stefania Petrosino, Caterina Scuderi, Vincenzo Di Marzo, Luca Steardo · 2007 · Journal of Molecular Medicine
- STAT1 Mediates Oroxylin A Inhibition of iNOS and Pro-Inflammatory Cytokines Expression in Microglial BV-2 CellsPo-Wen Liu, Meifang Chen, Andy Po‐Yi Tsai, Tony J.-F. Lee · 2012 · PLoS ONE
- Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in miceGao, Liang, Brenner, David, Llorens-Bobadilla, Enric, Saiz-Castro, Gonzalo, Frank, Tobias, Wieghofer, Peter, Hill, Oliver, Thiemann, Meinolf, Karray, Saoussen, Prinz, Marco et al. · 2015 · Journal of Experimental Medicine
- Enhanced Astrocytic Nitric Oxide Production and Neuronal Modifications in the Neocortex of a NOS2 Mutant MouseYossi Buskila, Yasmin Abu‐Ghanem, Yifat Levi, Arie Moran, Ettie Grauer, Yael Amitai · 2007 · PLoS ONE
- Full and partial peroxisome proliferation-activated receptor-gamma agonists, but not delta agonist, rescue of dopaminergic neurons in the 6-OHDA Parkinsonian model is associated with inhibition of microglial activation and MMP expressionMona Sadeghian, Lilia Marinova-Mutafchieva, Lauren Broom, Janet L. Davis, David J. Virley, Andrew D. Medhurst, David Trevor Dexter · 2012 · Journal of Neuroimmunology
- The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6Rituraj Niranjan, Chandishwar Nath, Rakesh Shukla · 2010 · Free Radical Research
- Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson diseaseCarmen Noelker, Lydie J. Morel, Anke Osterloh, Daniel Alvarez‐Fischer, Thomas Lescot, Minka Breloer, Maike Gold, Wolfgang Hermann Oertel, Carmen Henze, Patrick Pierre Michel et al. · 2014 · Journal of Neuroinflammation
- Aquaporin 4: A key player in Parkinson's diseaseOmid Reza Tamtaji, Mohammad Behnam, Mohammad Ali Pourattar, Hamed Jafarpour, Zatollah Asemi · 2019 · Journal of Cellular Physiology
- Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinson’s DiseaseChien‐Wei Feng, Nan‐Fu Chen, Chun‐Sung Sung, Hsiao‐Mei Kuo, San‐Nan Yang, Chien‐Liang Chen, Han-Chun Hung, Bing‐Hung Chen, Zhi‐Hong Wen, Wu-Fu Chen · 2019 · Frontiers in Neuroscience
- Upregulation of microglial C1q expression has no effects on nigrostriatal dopaminergic injury in the MPTP mouse model of Parkinson diseaseCandan Depboylu, Kathrin Schorlemmer, Martin Klietz, Wolfgang Hermann Oertel, Eberhard Weihe, Günter U. Höglinger, Martin K.-H. Schäfer · 2011 · Journal of Neuroimmunology
- Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxideWen Yi Zhang, Tomomi Gotoh, Seiichi Oyadomari, Masataka Mori · 2000 · Molecular Brain Research
- Commentary: Progressive inflammation as a contributing factor to early development of Parkinson's diseaseSuraj Pradhan, Katrin I. Andreasson · 2012 · Experimental Neurology
- Prothrombin kringle-2 induces death of mesencephalic dopaminergic neurons in vivo and in vitro via microglial activationKim, Sang Ryong, Chung, Eun Sook, Bok, Eugene, Baik, Hyung Hwan, Chung, Young Cheul, Won, So Yoon, Joe, Eunhye, Kim, Tae Hyong, Kim, Soung Soo, Jin, Min Young et al. · 2010 · Journal of Neuroscience Research
- Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridineGenaro Gabriel Ortíz, Fermín Paúl Pacheco-Moisés, Víctor M. Gómez-Rodríguez, Erika Daniela González-Renovato, Erandis D. Torres-Sánchez, Ana Cristina Ramírez Anguiano · 2013 · Metabolic Brain Disease
- Oxidative and nitrosative stress in serum of patients with Parkinson’s diseaseHikmet Can Çubukçu, Mustafa Yurtdaş, İlker Durak, Bilal Aytaç, Hafize Nalan Güneş, Burcu Gökçe Çokal, Tahir Kurtuluş Yoldaş, İlker Durak · 2016 · Neurological Sciences
- Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivoAnn Kristin Frøyset, Amanda J. Edson, Naouel Gharbi, Essa Ahsan Khan, Daniel Christiaan Dondorp, Qing Bai, Ettore Tiraboschi, Maximiliano L. Suster, Joanne B. Connolly, Edward A. Burton et al. · 2018 · Redox Biology
- GardeninA confers neuroprotection against environmental toxin in a Drosophila model of Parkinson’s diseaseUrmila Maitra, Thomas Harding, Qiaoli Liang, Lukasz M. Ciesla · 2021 · Communications Biology
- Mouse models of α-synucleinopathy and Lewy pathologyBernd Sommer, Samuel Barbieri, Katja Hofele, Karl‐Heinz Wiederhold, A. Probst, Claudia Mistl, Simone Danner, S Kauffmann, Will P. J. M. Spooren, Markus Tolnay et al. · 2000 · Experimental Gerontology
- Tumor necrosis factor-alpha receptor ablation in a chronic MPTP mouse model of Parkinson's diseaseAndreas Leng, Anna Mura, Joram Feldon, Boris Ferger · 2004 · Neuroscience Letters
- Role of nitric oxide synthase against MPTP neurotoxicity in miceR. Kurosaki, Y. Muramatsu, Mari Michimata, Mitsunobu Matsubara, Hisanori Kato, Y. Imai, Yasuto Itoyama, Tsutomu Araki · 2002 · Neurological Research
- Development of an electrochemical sensor for nitric oxide based on carbon paste electrode modified with Nafion, gold nanoparticles and graphene nanoribbonsNadine Wenninger, Urška Bračič, Alexander Kollau, Kingkan Pungjunun, Gerd Leitinger, Kurt Kalcher, Astrid Ortner · 2021 · Sensors and Actuators B Chemical
- Curcumin Protects Nigrostriatal Dopaminergic Neurons and Reduces Glial Activation in 6-Hydroxydopamine Hemiparkinsonian Mice ModelWanida Tripanichkul, Em-orn Jaroensuppaperch · 2011 · International Journal of Neuroscience
- Adenosine receptors in neurological disordersFrancesco Impagnatiello, Elena Bastia, Ennio Ongini, Angela Monopoli · 2000 · Emerging Therapeutic Targets
- α‐synuclein oligomers enhance astrocyte‐induced synapse formation through TGF‐β1 signaling in a Parkinson's disease modelLuan Pereira Diniz, Isadora C. Pereira Matias, Ana Paula Bérgamo Araújo, Matheus Nunes Garcia, Fernanda G. Q. Barros‐Aragão, Soniza Vieira Alves‐Leon, Jorge Marcondes de Souza, Débora Foguel, Cláudia Pinto Figueiredo, Carolina Alvares da Cunha de Azeredo Braga et al. · 2019 · Journal of Neurochemistry
- Nuclear factor kappa-B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low-level inflammatory stimulation with MPTPDavid L. Carbone, Julie A. Moreno, Ronald B. Tjalkens · 2008 · Brain Research
- Characterization and comparative analysis of a new mouse microglial cell model for studying neuroinflammatory mechanisms during neurotoxic insultsSouvarish Sarkar, Emir Malovic, Deeksha Sarda, Vivek Lawana, Dharmin Rokad, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy · 2018 · NeuroToxicology
- Selective Neuronal Death in Neurodegenerative Diseases: The Ongoing Mystery.Srinivasa Subramaniam · 2019 · Europe PMC (PubMed Central)
- A two-photon ratiometric fluorescent probe for real-time imaging and quantification of NO in neural stem cells during activation regulationMengyu Liang, Zhichao Liu, Zhonghui Zhang, Yuxiao Mei, Yang Tian · 2022 · Chemical Science
- A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: Pharmacological validation with R-(−)-deprenylLeann P. Quinn, M.J. Perren, Kim T. Brackenborough, P.L. Woodhams, Martin Vidgeon-Hart, Helen Chapman, Menelas N. Pangalos, Neil Upton, David J. Virley · 2007 · Journal of Neuroscience Methods
- PSMC5 Regulates Microglial Polarization and Activation in LPS-Induced Cognitive Deficits and Motor Impairments by Interacting with TLR4Bi, Wei, Bao, Keyao, Zhou, Xinqi, Deng, Yihui, Li, Xiaoting, Zhang, Jiawei, Lan, Xin, Zhao, Jiayi, Lu, Daxiang, Xu, Yezi et al. · 2023 · Journal of Neuroinflammation
- The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degenerationJanelle Drouin‐Ouellet, Claire Gibrat, M. Bousquet, Frédéric Calon, Jasna Križ, Francesca Cicchetti · 2011 · Journal of Neuroinflammation
- Arbutin attenuates behavioral impairment and oxidative stress in an animal model of Parkinson's disease.Masoumeh Dadgar, Mahdi Pouramir, Zohreh Dastan, Maryam Ghasemi‐Kasman, Manouchehr Ashrafpour, Ali Akbar Moghadamnia, Soraya Khafri, Mohsen Pourghasem · 2018 · Europe PMC (PubMed Central)
- 3,4-Dihydroxyphenylacetic acid (DOPAC) modulates the toxicity induced by nitric oxide in PC-12 cells via mitochondrial dysfunctioningCarla Nunes, Leonor M. Almeida, João A.N. Laranjinha · 2008 · NeuroToxicology
- Switching the Microglial Harmful Phenotype Promotes Lifelong Restoration of Subtantia Nigra Dopaminergic Neurons from Inflammatory Neurodegeneration in Aged MiceFrancesca L’Episcopo, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Maria C. Morale, Francesco Impagnatiello, Bianca Marchetti · 2011 · Rejuvenation Research
- Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian ratsKazuhiro Takuma, Tatsunori Tanaka, Tsuyoshi Takahashi, Naoki Hiramatsu, Yuki Ota, Yukio Ago, Toshio Matsuda · 2012 · European Journal of Pharmacology
- trans ‐Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide StimulationYan Fu, Pin Yang, Yang Zhao, Liqing Zhang, Zhangang Zhang, Xianwen Dong, Zhongping Wu, Ying Xu, Yongjun Chen · 2017 · Evidence-based Complementary and Alternative Medicine
- Immunoregulation of microglial polarization: an unrecognized physiological function of α-synucleinNa Li, Tessandra Stewart, Lifu Sheng, Min Yan Shi, Eugene M. Cilento, Yufeng Wu, Jau-Syong Hong, Jing Zhang · 2020 · Journal of Neuroinflammation
- Glial Cell Response: A Pathogenic Factor in Parkinson's DiseaseDu Chu Wu, Kim Tieu, Oren S. Cohen, Dong‐Kug Choi, Miquel Vila, Vernice R. Jackson-Lewis, Peter Teismann, Serge Przedborski · 2002 · Journal of NeuroVirology
- Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthasesAna López, Francisco Ortiz, Carolina Doerrier, Carmen Venegas, Marisol Fernández‐Ortiz, Paula Aranda‐Martínez, María Elena Díaz-Casado, Beatriz I. Fernández-Gil, Eliana Barriocanal‐Casado, Germaine Escames et al. · 2017 · PLoS ONE
- Nitric oxide‐producing microglia mediate thrombin‐induced degeneration of dopaminergic neurons in rat midbrain slice cultureHiroshi Katsuki, Mitsugi Okawara, Haruki Shibata, Toshiaki Kume, Akinori Akaike · 2006 · Journal of Neurochemistry
- Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicityBin Xing, Tao Xin, Lingling Zhao, Randy L. Hunter, Yan Chen, Guoying Bing · 2010 · Journal of Neuroimmunology
- Parasitic manipulation and neuroinflammation: Evidence from the system Microphallus papillorobustus (Trematoda) - Gammarus (Crustacea)Simone Helluy, Frédéric Thomas A · 2010 · Parasites & Vectors