Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

Rab GTPases as coordinators of vesicle traffic

Stenmark, H. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2728 · Cited by 3,413

Rab proteins as membrane organizers

Zerial, M., & McBride, H. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35052055 · Cited by 3,381

Secretory Granule Exocytosis

Burgoyne, R. D., & Morgan, A. (2003) · Physiological Reviews · doi:10.1152/physrev.00031.2002 · Cited by 934

The Immunology of Macrophage Activation Syndrome

Crayne, C. B., Albeituni, S., Nichols, K. E., & Cron, R. Q. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00119 · Cited by 633

Perforin-mediated target-cell death and immune homeostasis

Voskoboinik, I., Smyth, M. J., & Trapani, J. A. (2006) · Nature reviews. Immunology · doi:10.1038/nri1983 · Cited by 592

Rab Proteins and the Compartmentalization of the Endosomal System

Wandinger-Ness, A., & Zerial, M. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a022616 · Cited by 586

A Family of Rab27-binding Proteins

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Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

Mazodier, K. (2005) · Blood · doi:10.1182/blood-2005-05-1980 · Cited by 290

Exome Sequencing and the Management of Neurometabolic Disorders

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RAB23 Mutations in Carpenter Syndrome Imply an Unexpected Role for Hedgehog Signaling in Cranial-Suture Development and Obesity

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Gene expression profiling of peripheral blood from patients with untreated new‐onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome

Fall, N., Barnes, M., Thornton, S., Luyrink, L., Olson, J., Ilowite, N. T., Gottlieb, B. S., Griffin, T., Sherry, D. D., Thompson, S., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22981 · Cited by 245

SNAREing immunity: the role of SNAREs in the immune system

Stow, J. L., Manderson, A. P., & Murray, R. Z. (2006) · Nature Reviews Immunology · doi:10.1038/nri1980 · Cited by 235

Ferritin is secreted via 2 distinct nonclassical vesicular pathways

Truman-Rosentsvit, M., Berenbaum, D., Spektor, L., Cohen, L. A., Belizowsky-Moshe, S., Lifshitz, L., Ma, J., Li, W., Kesselman, E., Abutbul-Ionita, I., et al. (2018) · Blood · doi:10.1182/blood-2017-02-768580 · Cited by 223

The Rab27a/Granuphilin Complex Regulates the Exocytosis of Insulin-Containing Dense-Core Granules

Yi, Z., Yokota, H., Torii, S., Aoki, T., Hosaka, M., Zhao, S., Takata, K., Takeuchi, T., & Izumi, T. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.6.1858-1867.2002 · Cited by 228

Rab27a

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The road to lysosome-related organelles: Insights from Hermansky-Pudlak syndrome and other rare diseases

Bowman, S. L., Bi‐Karchin, J., Le, L., & Marks, M. S. (2019) · Traffic · doi:10.1111/tra.12646 · Cited by 219

Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis

Kaufman, K. M., Linghu, B., Szustakowski, J. D., Husami, A., Yang, F., Zhang, K., Filipovich, A. H., Fall, N., Harley, J. B., Nirmala, N. R., et al. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38793 · Cited by 207

MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes

El‐Amraoui, A., Schonn, J., Küssel‐Andermann, P., Blanchard, S., Desnos, C., Henry, J., Wolfrum, U., Darchen, F., & Petit, C. (2002) · The EMBO Reports · doi:10.1093/embo-reports/kvf090 · Cited by 187

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

Krzewski, K., Gil-Krzewska, A., Nguyen, V., Peruzzi, G., & Coligan, J. E. (2013) · Blood · doi:10.1182/blood-2012-08-453738 · Cited by 170

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes

Gibbs, D., Azarian, S. M., Lillo, C., Kitamoto, J., Klomp, A. E., Steel, K. P., Libby, R. T., & Williams, D. S. (2004) · Journal of Cell Science · doi:10.1242/jcs.01580 · Cited by 152

Pleiotropic effects of coat colour-associated mutations in humans, mice and other mammals

Reissmann, M., & Ludwig, A. (2013) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2013.03.014 · Cited by 149

Detecting adaptive introgression in human evolution using convolutional neural networks

Gower, G., Picazo, P. I., Fumagalli, M., & Racimo, F. (2021) · eLife · doi:10.7554/elife.64669 · Cited by 95

Rim2α Determines Docking and Priming States in Insulin Granule Exocytosis

Yasuda, T., Shibasaki, T., Minami, K., Takahashi, H., Mizoguchi, A., Uriu, Y., Numata, T., Mori, Y., Miyazaki, J.-I., Miki, T., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.05.017 · Cited by 110

The Recycling Endosome Protein Rab17 Regulates Melanocytic Filopodia Formation and Melanosome Trafficking

Beaumont, K. A., Hamilton, N. A., Moores, M. T., Brown, D. L., Ohbayashi, N., Cairncross, O., Cook, A. L., Smith, A. G., Misaki, R., Fukuda, M., et al. (2011) · Traffic · doi:10.1111/j.1600-0854.2011.01172.x · Cited by 97

Granuphilin Modulates the Exocytosis of Secretory Granules through Interaction with Syntaxin 1a

Torii, S., Zhao, S., Yi, Z., Takeuchi, T., & Izumi, T. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.15.5518-5526.2002 · Cited by 94

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis

Fujiwara, T., Ye, S., Castro-Gomes, T., Winchell, C. G., Andrews, N. W., Voth, D. E., Varughese, K. I., Mackintosh, S. G., Feng, Y., Pavlos, N., et al. (2016) · JCI Insight · doi:10.1172/jci.insight.86330 · Cited by 92

Involvement of Rab27b in the Regulated Secretion of Pituitary Hormones

Zhao, S., Torii, S., Yokota-Hashimoto, H., Takeuchi, T., & Izumi, T. (2002) · Endocrinology · doi:10.1210/endo.143.5.8823 · Cited by 90

Rab GTPases: Key players in melanosome biogenesis, transport, and transfer

Fukuda, M. (2021) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12931 · Cited by 78

Rab GTPases implicated in inherited and acquired disorders

Mitra, S., Cheng, K. W., & Mills, G. B. (2011) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2010.12.005 · Cited by 78

CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer

Macpherson, I. R., Rainero, E., Mitchell, L. E., van den Berghe, P. V., Speirs, C., Dozynkiewicz, M. A., Chaudhary, S., Kalna, G., Edwards, J., Timpson, P., et al. (2014) · Journal of Cell Science · doi:10.1242/jcs.135947 · Cited by 77

Hemophagocytic lymphohistiocytosis and primary immune deficiency disorders

Faitelson, Y., & Grunebaum, E. (2014) · Clinical Immunology · doi:10.1016/j.clim.2014.09.008 · Cited by 51

Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34

Chen, L., Hu, J., Yun, Y., & Wang, T. (2010) · Molecular Membrane Biology · doi:10.3109/09687680903417470 · Cited by 51

The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis

Wang, X.-M., Yik, W. Y., Zhang, P., Lu, W., Dranchak, P. K., Shibata, D., Steinberg, S. J., & Hacia, J. G. (2012) · Stem Cell Research & Therapy · doi:10.1186/scrt130 · Cited by 33

Role of Rab27 in synaptic transmission at the squid giant synapse

Yu, E., Kanno, E., Choi, S., Sugimori, M., Moreira, J. E., Llinás, R. R., & Fukuda, M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804825105 · Cited by 31

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

Yatsu, A., Shimada, H., Ohbayashi, N., & Fukuda, M. (2015) · Biology Open · doi:10.1242/bio.201411114 · Cited by 28