A neural circuit for circadian regulation of arousal

Aston-Jones, Gary, Chen, Sheng, Zhu, Yan, Oshinsky, Michael L.·2001·Nature Neuroscience
DOI 10.1038/89522

Cited by (633)

Items 101–200 of 633

  1. Functional Organization of the Sympathetic Pathways Controlling the Pupil: Light-Inhibited and Light-Stimulated Pathways
    E. Szabadi · 2018 · Frontiers in Neurology
  2. Dopaminergic—adrenergic interactions in the wake promoting mechanism of modafinil
    Jonathan P. Wisor, Krister S. Eriksson · 2005 · Neuroscience
  3. An Endogenous Circadian Rhythm in Sleep Inertia Results in Greatest Cognitive Impairment upon Awakening during the Biological Night
    Frank A. J. L. Scheer, Thomas J. Shea, Michael F. Hilton, Steven A. Shea · 2008 · Journal of Biological Rhythms
  4. Serotonin Affects Movement Gain Control in the Spinal Cord
    Wei, K., Glaser, J. I., Deng, L., Thompson, C. K., Stevenson, I. H., Wang, Q., Hornby, T. G., Heckman, C. J., Kording, K. P. · 2014 · Journal of Neuroscience
  5. Intravitreal Injection of the Attenuated Pseudorabies Virus PRV Bartha Results in Infection of the Hamster Suprachiasmatic Nucleus Only by Retrograde Transsynaptic Transport via Autonomic Circuits
    Gary E. Pickard, Cynthia A. Smeraski, Christine C. Tomlinson, Bruce W. Banfield, Jessica D. Kaufman, Christine L. Wilcox, Lynn W. Enquist, Patricia J. Sollars · 2002 · Journal of Neuroscience
  6. Importance of the locus coeruleus-norepinephrine system in sleep-wake regulation: Implications for aging and Alzheimer's disease
    Maxime Van Egroo, Ekaterina Koshmanova, Gilles Vandewalle, Heidi I.L. Jacobs · 2022 · Sleep Medicine Reviews
  7. A molecular perspective of human circadian rhythm disorders
    Nicolas Cermakian, Diane B. Boivin · 2003 · Brain Research Reviews
  8. Central CO2chemoreception and integrated neural mechanisms of cardiovascular and respiratory control
    Patrice G. Guyenet, Ruth L. Stornetta, Stephen B.G. Abbott, Seth D. DePuy, Michal G. Fortuna, Roy Kanbar · 2010 · Journal of Applied Physiology
  9. Selective Optogenetic Activation of Rostral Ventrolateral Medullary Catecholaminergic Neurons Produces Cardiorespiratory Stimulation in Conscious Mice
    Stephen B.G. Abbott, Seth D. DePuy, Thành Nguyễn, Melissa B. Coates, Ruth L. Stornetta, Patrice G. Guyenet · 2013 · Journal of Neuroscience
  10. A role for sleep in brain plasticity
    Thien Thanh Dang‐Vu, Martin Desseilles, Philippe Peigneux, Pierre Maquet · 2006 · Developmental Neurorehabilitation
  11. Biological rhythms, higher brain function, and behavior: Gaps, opportunities, and challenges
    Benca, Ruth, Duncan, Marilyn J., Frank, Ellen, McClung, Colleen, Nelson, Randy J., Vicentic, Aleksandra · 2009 · Brain Research Reviews
  12. Genetic Evidence for a Role of CREB in Sustained Cortical Arousal
    Laurel A. Graves, Kevin M. Hellman, Sigrid Carlen Veasey, Julie A. Blendy, Allan I Pack, Ted G. Abel · 2003 · Journal of Neurophysiology
  13. Peripheral Circadian Oscillators in Mammals
    Steven A. Brown, Abdelhalim Azzi · 2013 · Handbook of experimental pharmacology
  14. Circadian insights into dopamine mechanisms
    Jorge Mendoza, Étienne Challet · 2014 · Neuroscience
  15. Pathophysiological basis of migraine prophylaxis
    Francesca Galletti, Letizia Maria Cupini, Ilenia Corbelli, Paolo Calabresi, Paola Sarchielli · 2009 · Progress in Neurobiology
  16. Entrainment of Circadian Rhythms Depends on Firing Rates and Neuropeptide Release of VIP SCN Neurons
    Cristina N. Mazuski, John H. Abel, Samantha P. Chen, Tracey O. Hermanstyne, Jeff R. Jones, Tatiana Simon, Francis J. Doyle, Erik D. Herzog · 2018 · Neuron
  17. Functional neuroanatomy of sleep and circadian rhythms
    Alan M. Rosenwasser · 2009 · Brain Research Reviews
  18. Current Prophylactic Medications for Migraine and Their Potential Mechanisms of Action
    Till Sprenger, Michele Viana, Cristina Tassorelli · 2018 · Neurotherapeutics
  19. The brain's master circadian clock: Implications and opportunities for therapy of sleep disorders
    Phyllis C. Zee, Prasanth Manthena · 2006 · Sleep Medicine Reviews
  20. Circadian rhythms in executive function during the transition to adolescence: the effect of synchrony between chronotype and time of day
    Constanze Hahn, Jason M. Cowell, Ursula J. Wiprzycka, David Goldstein, Martin Roland Ralph, Lynn Hasher, Philip David Zelazo · 2012 · Developmental Science
  21. Expression of prokineticins and their receptors in the adult mouse brain
    Michelle Cheng, Frances M. Leslie, Qun‐Yong Zhou · 2006 · The Journal of Comparative Neurology
  22. Adrenergic Signaling Plays a Critical Role in the Maintenance of Waking and in the Regulation of REM Sleep
    Ming Ouyang, Kevin M. Hellman, Ted G. Abel, STEVEN A. THOMAS · 2004 · Journal of Neurophysiology
  23. Orexin Neurons Are Necessary for the Circadian Control of REM Sleep
    Sándor Kántor, Takatoshi Mochizuki, Agnieszka M. Janisiewicz, Erika L. Clark, Seiji Nishino, Thomas E. Scammell · 2009 · SLEEP
  24. Neurofeedback in ADHD and insomnia: Vigilance stabilization through sleep spindles and circadian networks
    Martijn Arns, J. Leon Kenemans · 2012 · Neuroscience & Biobehavioral Reviews
  25. A new neuron model under electromagnetic field
    Fuqiang Wu, Jun Ma, Ge Zhang · 2018 · Applied Mathematics and Computation
  26. Adenosine, Caffeine, and Performance: From Cognitive Neuroscience of Sleep to Sleep Pharmacogenetics
    Emily Urry, Hans‐Peter Landolt · 2014 · Current topics in behavioral neurosciences
  27. A Wake-Promoting Circadian Output Circuit in Drosophila
    Angélique Lamaze, Patrick Krätschmer, Ko‐Fan Chen, Simon A. Lowe, James E.C. Jepson · 2018 · Current Biology
  28. Abnormal Sleep, Circadian Rhythm Disruption, and Delirium in the ICU: Are They Related?
    Marietou Daou, Irene Telías, Magdy K. Younes, Laurent Jean Brochard, Mary Elizabeth Wilcox · 2020 · Frontiers in Neurology
  29. A Local, Bottom-Up Perspective on Sleep Deprivation and Neurobehavioral Performance
    Hans P. A. Van Dongen, Gregory Lucas Belenky, James M. Krueger · 2011 · Current Topics in Medicinal Chemistry
  30. The hypocretins and sleep
    de Lecea, Luis, Sutcliffe, J. Gregor · 2005 · The FEBS Journal
  31. The development of sleep–wake rhythms and the search for elemental circuits in the infant brain.
    Mark Samuel BLUMBERG, Andrew J. Gall, William D. Todd · 2014 · Behavioral Neuroscience
  32. Sleep- and circadian rhythm–associated pathways as therapeutic targets in bipolar disorder
    Bellivier, Frank, Geoffroy, Pierre-Alexis, Etain, Bruno, Scott, Jan · 2015 · Expert Opinion on Therapeutic Targets
  33. When the Locus Coeruleus Speaks Up in Sleep: Recent Insights, Emerging Perspectives
    Alejandro Osorio-Forero, Najma Cherrad, Lila Banterle, Laura M. J. Fernandez, Anita Lüthi · 2022 · International Journal of Molecular Sciences
  34. Regulation and function of extra‐SCN circadian oscillators in the brain
    Kimberly Begemann, Anne‐Marie Neumann, Henrik Oster · 2020 · Acta Physiologica
  35. Time after time: inputs to and outputs from the mammalian circadian oscillators
    David Morse, Paolo Sassone‐Corsi · 2002 · Trends in Neurosciences
  36. Modulation of physiological reflexes by pain: role of the locus coeruleus
    E. Szabadi · 2012 · Frontiers in Integrative Neuroscience
  37. The effects of red and blue light on alertness and mood at night
    Barbara Plitnick, Mariana G. Figueiro, Brittany Wood, Mark S. Rea · 2010 · Lighting Research & Technology
  38. Regional brain glucose metabolism during morning and evening wakefulness in humans: Preliminary findings
    Buysse, Daniel J., Nofzinger, Eric A., Germain, Anne, Meltzer, Carolyn C., Wood, Annette, Ombao, Hernando, Kupfer, David J., Moore, Robert Y. · 2004 · SLEEP
  39. Medial vestibular connections with the hypocretin (orexin) system
    Seth S. Horowitz, Jane H. Blanchard, Lawrence P. Morin · 2005 · The Journal of Comparative Neurology
  40. Exposure to Blue Light Increases Subsequent Functional Activation of the Prefrontal Cortex During Performance of a Working Memory Task
    Anna Alkozei, Ryan S. Smith, Derek Pisner, John R. Vanuk, Sarah M. Berryhill, Andrew Fridman, Bradley R. Shane, Sara A. Knight, William D. S. Killgore · 2016 · SLEEP
  41. Chemogenetic Activation of Melanopsin Retinal Ganglion Cells Induces Signatures of Arousal and/or Anxiety in Mice
    Nina Milosavljevic, Jasmina Cehajic‐Kapetanovic, Christopher A. Procyk, Robert James Lucas · 2016 · Current Biology
  42. Circadian rhythms and pain
    Jacob R. Bumgarner, William H. Walker, Randy J. Nelson · 2021 · Neuroscience & Biobehavioral Reviews
  43. Indirect projections from the suprachiasmatic nucleus to the ventrolateral preoptic nucleus: a dual tract‐tracing study in rat
    Samüel Deurveilher, Joan Burns, Kazue Semba · 2002 · European Journal of Neuroscience
  44. Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception
    Marei Warnecke, Henrik Oster, Jean-Pierre Revelli, Gonzalo Álvarez-Bolado, Gregor Eichele C · 2005 · Genes & Development
  45. Prokineticin 2 and circadian clock output
    Qun‐Yong Zhou, Michelle Cheng · 2005 · FEBS Journal
  46. Characterization of cannabinoid-1 receptors in the locus coeruleus: Relationship with mu-opioid receptors
    Jillian L. Scavone, Ken Mackie, Elisabeth J. Van Bockstaele · 2009 · Brain Research
  47. Neural Correlates of Migration: Activation of Hypothalamic Clock(s) in and out of Migratory State in the Blackheaded Bunting (Emberiza melanocephala)
    Ashutosh Rastogi, Yatinesh Kumari, Sangeeta Rani, Vinod Kumar · 2013 · PLoS ONE
  48. Functional plasticity of the circadian timing system in old age: light exposure
    Eus J.W. Van Someren, Rixt F. Riemersma, Dick Frans Swaab · 2002 · Progress in brain research
  49. Monoaminergic Modulation of Motor Cortex Function
    Clément Vitrac, Marianne Benoit‐Marand · 2017 · Frontiers in Neural Circuits
  50. Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity
    Heinrich S. Gompf, Gary Aston‐Jones · 2008 · Brain Research
  51. Multilevel Interactions of Stress and Circadian System: Implications for Traumatic Stress
    Agorastos Agorastos, Nicolas C. Nicolaides, Vasilios P. Bozikas, George Panagiotis Chrousos, Panagiota Pervanidou · 2020 · Frontiers in Psychiatry
  52. Why Trypanosomes Cause Sleeping Sickness
    Gabriella B. S. Lundkvist, Krister Kristensson, Marina Bentivoglio · 2004 · Physiology
  53. Circadian biomarkers, circadian genes and bipolar disorders
    Vanessa Milhiet, Bruno Étain, Carole Boudebesse, Frank Bellivier · 2011 · Journal of Physiology-Paris
  54. Intergeniculate leaflet and ventral lateral geniculate nucleus afferent connections: An anatomical substrate for functional input from the vestibulo‐visuomotor system
    Seth S. Horowitz, Jane H. Blanchard, Lawrence P. Morin · 2004 · The Journal of Comparative Neurology
  55. Circadian Preference Modulates the Neural Substrate of Conflict Processing across the Day
    Christina Schmidt, Philippe Peigneux, Yves Leclercq, Virginie Sterpenich A, Gilles Vandewalle, Christophe L. M. Phillips, Pierre Berthomier, Christian Berthomier, Gilberte Tinguely, Steffen Gais et al. · 2012 · PLoS ONE
  56. Organization of cell and tissue circadian pacemakers: A comparison among species
    Mariska J. Vansteensel, Stephan H. Michel, Johanna H. Meijer · 2007 · Brain Research Reviews
  57. Altered circadian profiles in attention-deficit/hyperactivity disorder: An integrative review and theoretical framework for future studies
    Lindita Imeraj, Edmund J. S. Sonuga-Barke, Inge Antrop, Herbert Roeyers, Roeljan Wiersema, Sarah Bal, Dirk Deboutte · 2012 · Neuroscience & Biobehavioral Reviews
  58. Lateral Hypothalamic Orexin/Hypocretin Neurons That Project to Ventral Tegmental Area Are Differentially Activated with Morphine Preference
    Kimberlei A. Richardson, Gary Aston‐Jones · 2012 · Journal of Neuroscience
  59. Altered Circadian and Homeostatic Sleep Regulation in Prokineticin 2-Deficient Mice
    Wang‐Ping Hu, Jia‐Da Li, Chengkang Zhang, Lisa N Boehmer, Jerome M. Siegel, Qun-Yong Zhou · 2007 · SLEEP
  60. Circadian regulation of membrane physiology in neural oscillators throughout the brain
    Jodi R. Paul, Jennifer A. Davis, Lacy K. Goode, Bryan Becker, Allison R. Fusilier, Aidan Meador-Woodruff, Karen L. Gamble · 2019 · European Journal of Neuroscience
  61. Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal
    G. C. M. Harris, Gary Aston‐Jones · 2006 · Behavioural Brain Research
  62. Development of circadian rhythms: Role of postnatal light environment
    Elisabeth Brooks, Maria Mercè Canal · 2013 · Neuroscience & Biobehavioral Reviews
  63. Biological Timekeeping
    Martha Ulbrick Gillette, Sabra M. Abbott, Jennifer M. Arnold · 2012 · Sleep Medicine Clinics
  64. The cognitive impact of light: illuminating ipRGC circuit mechanisms
    Heather L. Mahoney, Tiffany M. Schmidt · 2024 · Nature reviews. Neuroscience
  65. The hypocretin/orexin system in health and disease
    Seiji Nishino · 2003 · Biological Psychiatry
  66. Melancholic-Like Behaviors and Circadian Neurobiological Abnormalities in Melatonin MT1 Receptor Knockout Mice
    Stefano Comai, Rafael Ochoa‐Sanchez, Sergio Domínguez-López, Francis Rodriguez Bambico, Gabriella Gobbi · 2015 · The International Journal of Neuropsychopharmacology
  67. Circadian Mechanisms Underlying Reward-Related Neurophysiology and Synaptic Plasticity
    Puja K. Parekh, Colleen A. McClung · 2016 · Frontiers in Psychiatry
  68. The Neurobiology of Circadian Rhythms
    Patricia J. Sollars, Gary E. Pickard · 2015 · Psychiatric Clinics of North America
  69. Physiologically-based modeling of sleep–wake regulatory networks
    Victoria Booth, Cecilia Diniz Behn · 2014 · Mathematical Biosciences
  70. What keeps us awake?–the role of clocks and hourglasses, light, and melatonin
    Cajochen, Christian, Chellappa, Sarah, Schmidt, Christina · 2010 · International review of neurobiology
  71. Sleep and Headache
    K. C. Brennan, Andrew C. Charles · 2009 · Seminars in Neurology
  72. A Quartet Neural System Model Orchestrating Sleep and Wakefulness Mechanisms
    Yuichi Tamakawa, Akihiro Karashima, Yoshimasa Koyama, N. Katayama, Mitsuyuki Nakao · 2005 · Journal of Neurophysiology
  73. Circadian Rhythms and Measures of CNS/Autonomic Interaction
    Francesco Riganello, Valeria Prada, Andrea Soddu, Carol Di Perri, Walter G. Sannita · 2019 · International Journal of Environmental Research and Public Health
  74. Pushing the Limits: Chronotype and Time of Day Modulate Working Memory-Dependent Cerebral Activity
    Christina Schmidt, Fabienne Collette, Carolin Reichert, Micheline Maire, Gilles Vandewalle, Philippe Peigneux, Christian Cajochen · 2015 · Frontiers in Neurology
  75. Transgenic approach reveals expression of the VPAC2 receptor in phenotypically defined neurons in the mouse suprachiasmatic nucleus and in its efferent target sites
    Imre Kalló, Theodosis Κalamatianos, Nzinga Wiltshire, Sanbing Shen, W. John Sheward, Anthony J. Harmar, Clive W. Coen · 2004 · European Journal of Neuroscience
  76. Delayed Orexin Signaling Consolidates Wakefulness and Sleep: Physiology and Modeling
    Cecilia Diniz Behn, Nancy Kopell, Emery N. Brown, Takatoshi Mochizuki, Thomas E. Scammell · 2008 · Journal of Neurophysiology
  77. Layer- and area-specific actions of norepinephrine on cortical synaptic transmission
    Humberto Salgado, Mario Treviño, Marco Atzori · 2016 · Brain Research
  78. The circadian clock at the intercept of sleep and pain
    Vinko Palada, Ian Gilron, Barbara Canlon, Camilla I. Svensson, Eija Anneli Kalso · 2019 · Pain
  79. Circadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: Insights from a transgenic mouse model
    L David Willison, Takashi Kudo, Dawn H. Loh, Dika A. Kuljis, Christopher Scott Colwell · 2013 · Experimental Neurology
  80. Expression of VIP and/or PACAP receptor mRNA in peptide synthesizing cells within the suprachiasmatic nucleus of the rat and in its efferent target sites
    Theodosis Κalamatianos, Imre Kalló, Hugh David Piggins, Clive W. Coen · 2004 · The Journal of Comparative Neurology
  81. Inputs and Outputs of the Mammalian Circadian Clock
    Ashley N. Starnes, Jeff R. Jones · 2023 · Biology
  82. Locus coeruleus neurons originate in alar rhombomere 1 and migrate into the basal plate: Studies in chick and mouse embryos
    Pilar Aroca, Beatriz Lorente-Cánovas, Francisco R. Mateos, Luis Puelles · 2006 · The Journal of Comparative Neurology
  83. Physiological links of circadian clock and biological clock of aging
    Fang Liu, Hung-Chun Chang · 2017 · Protein & Cell
  84. Noradrenergic ensemble-based modulation of cognition over multiple timescales
    Nelson K. B. Totah, Nikos K. Logothetis, Oxana Eschenko · 2018 · Brain Research
  85. Paraventricular–subparaventricular hypothalamic lesions selectively affect circadian function
    Robert Y. Moore, Rebecca L. Danchenko · 2002 · Chronobiology International
  86. Effects of HF-rTMS over the left and right DLPFC on proactive and reactive cognitive control
    Matías M. Pulopulos, Jens Allaert, Marie–Anne Vanderhasselt, Álvaro Sánchez-López, Sara De Witte, Chris Baeken, Rudi De Raedt · 2020 · Social Cognitive and Affective Neuroscience
  87. Roles of tau pathology in the locus coeruleus (LC) in age-associated pathophysiology and Alzheimer’s disease pathogenesis: Potential strategies to protect the LC against aging
    Akiko Satoh, Koichi Iijima · 2017 · Brain Research
  88. The hypothalamus in episodic brain disorders
    Sebastiaan Overeem, Jorine A van Vliet, Gert Jan Lammers, Frans G. Zitman, Dick Frans Swaab, Michel Dominique Ferrari · 2002 · The Lancet Neurology
  89. Developmental divergence of sleep‐wake patterns in orexin knockout and wild‐type mice
    Mark Samuel BLUMBERG, Cassandra M. Coleman, Eric D. Johnson, Cynthia S. Shaw · 2007 · European Journal of Neuroscience
  90. The Attenuated Pseudorabies Virus Vaccine Strain Bartha K61: A Brief Review on the Knowledge Gathered during 60 Years of Research
    Jonas L. Delva, Hans Nauwynck, Thomas C. Mettenleiter, Herman W. Favoreel · 2020 · Pathogens
  91. The Circadian System Contributes to Apnea Lengthening across the Night in Obstructive Sleep Apnea
    Matthew P. Butler, Carolina Smales, Huijuan Wu, Mohammad V. Hussain, Yusef A. Mohamed, Miki Morimoto, Steven A. Shea · 2015 · SLEEP
  92. Hypothalamic contribution to sleep–wake cycle development
    Karl Æ. Karlsson, Joy C. Kreider, Mark Samuel BLUMBERG · 2003 · Neuroscience
  93. Suprachiasmatic nucleus projection to the medial prefrontal cortex: a viral transneuronal tracing study
    Sylvester, C.M, Krout, K.E, Loewy, A.D · 2002 · Neuroscience
  94. A Review of Sleep and Its Disorders in Patients with Parkinson's Disease in Relation to Various Brain Structures
    Isobel Timothea French, Kalai Arasu Muthusamy · 2016 · Frontiers in Aging Neuroscience
  95. Emerging from an unresponsive wakefulness syndrome: Brain plasticity has to cross a threshold level
    Sergio Bagnato, Cristina Boccagni, Antonino Santangelo, Alexander A. Fingelkurts, Andrew A. Fingelkurts, Giuseppe Galardi · 2013 · Neuroscience & Biobehavioral Reviews
  96. Weak relationships between suppression of melatonin and suppression of sleepiness/fatigue in response to light exposure
    Melanie Rüger, Marijke C. M. Gordijn, Domien G. M. Beersma, Bonnie de Vries, Serge Daan · 2005 · Journal of Sleep Research
  97. Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters
    Pamela Snodgrass-Belt, Jenifer L. Gilbert, Fred C. Davis · 2005 · Brain Research
  98. Circadian and Sleep-Wake Dependent Impact on Neurobehavioral Function
    Christian Cajochen, Katharina Blatter, Dieter Wallach · 2004 · Psychologica Belgica
  99. Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy
    Sebastiaan Overeem, Thomas E. Scammell, Gert Jan Lammers · 2002 · Current Opinion in Neurology
  100. Adrenergic Signaling in Circadian Control of Immunity
    Sarah Leach, Kazuhiro Suzuki · 2020 · Frontiers in Immunology