The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Laboratory animals as surrogate models of human obesity
Open accessAbstract
Obesity and obesity-related metabolic diseases represent a growing socioeconomic problem throughout the world. Great emphasis has been put on establishing treatments for this condition, including pharmacological intervention. However, there are many obstacles and pitfalls in the development process from pre-clinical research to the pharmacy counter, and there is no certainty that what has been observed pre-clinically will translate into an improvement in human health. Hence, it is important to test potential new drugs in a valid translational model early in their development. In the current mini-review, a number of monogenetic and polygenic models of obesity will be discussed in view of their translational character.
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Citations
Cites
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Cited by
Collins, K. H., Herzog, W., MacDonald, G. Z., Reimer, R. A., Rios, J. L., Smith, I. C., Zernicke, R. F., & Hart, D. A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00112 · Cited by 308
Obesity Impairs the Adaptive Immune Response to Influenza Virus
Green, W. D., & Beck, M. A. (2017) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201706-447aw · Cited by 253
John, L. M., Petersen, N., Gerstenberg, M. K., Torz, L., Pedersen, K., Christoffersen, B. Ø., & Kuhre, R. E. (2022) · Communications Biology · doi:10.1038/s42003-022-03895-8 · Cited by 31
Metadata
- Authors
- Nilsson, C., Raun, K., Yan, F.-F., Larsen, M. O., & Tang-Christensen, M.
- Venue
- Acta Pharmacologica Sinica
- Published
- 2012-02
- Volume
- 33
- Issue
- 2
- Pages
- 173-181
- ISSN
- 0253-9756 (ISSN-L)
- 1671-4083
- 1745-7254
- OpenAlex
- W1971297175
- Cited by
- 275
- References
- 84
- FWCI
- 4.80
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
