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Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization

Gong, Xin, Qian, Hongwu, Shao, Wei, Li, Jingxian, Wu, Jianping, Liu, Jun-Jie, Li, Wenqi, Wang, Hong-Wei, Espenshade, Peter, Yan, Nieng·2016·Cell Research
DOI 10.1038/cr.2016.123PMC PMC5099872
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Crossref · 10.1038/cr.2016.123

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  • SREBP-2 is synthesized as an inactive form and anchored to the ER membrane by SCAP, in a 4:4 oligomer ratio in yeast.

    “SREBP-2 is synthesized as an inactive form and anchored to the ER membrane by SREBP-cleavage activating protein (SCAP), in a 4:4 oligomer ratio in yeast68.”

    From Pathways and Molecular Mechanisms Governing LDL Receptor Regulation (2025) · cites this paper as [68]

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Research works printed but not linked: 38

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  9. Hughes AL, Todd BL, Espenshade PJ . SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 2005; 120:831–842. · DOI · Paper page
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Metadata

Authors
Gong, X., Qian, H., Shao, W., Li, J., Wu, J., Liu, J.-J., Li, W., Wang, H.-W., Espenshade, P., & Yan, N.
Venue
Cell Research
Publisher
Springer Science and Business Media LLC
Published
2016-11
Volume
26
Issue
11
Pages
1197-1211
ISSN
  • 1001-0602
  • 1748-7838
DOI
10.1038/cr.2016.123
PMC
PMC5099872
Cited by
31
References
2
Language
en
Licence
creativecommons.org/licenses/by-nc-sa/4.0 (tdm)

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