Circular RNAs: splicing’s enigma variations

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990

Natural RNA circles function as efficient microRNA sponges

Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K., & Kjems, J. (2013) · Nature · doi:10.1038/nature11993 · Cited by 7,985

Circular RNAs are abundant, conserved, and associated with ALU repeats

Jeck, W. R., Sorrentino, J. A., Wang, K., Slevin, M. K., Burd, C. E., Liu, J., Marzluff, W. F., & Sharpless, N. E. (2013) · RNA · doi:10.1261/rna.035667.112 · Cited by 4,388

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

Salzman, J., Gawad, C., Wang, P. L., Lacayo, N., & Brown, P. O. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030733 · Cited by 2,239

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

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Circular transcripts of the testis-determining gene Sry in adult mouse testis

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miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA

Hansen, T. B., Wiklund, E. D., Bramsen, J. B., Villadsen, S. B., Statham, A. L., Clark, S. J., & Kjems, J. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.359 · Cited by 996

Initiation of Protein Synthesis by the Eukaryotic Translational Apparatus on Circular RNAs

Chen, C.-Y., & Sarnow, P. (1995) · Science · doi:10.1126/science.7536344 · Cited by 766

Emerging Roles for Natural MicroRNA Sponges

Ebert, M. S., & Sharp, P. A. (2010) · Current Biology · doi:10.1016/j.cub.2010.08.052 · Cited by 490

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

Mercer, T. R., Gerhardt, D. J., Dinger, M. E., Crawford, J., Trapnell, C., Jeddeloh, J. A., Mattick, J. S., & Rinn, J. L. (2011) · Nature Biotechnology · doi:10.1038/nbt.2024 · Cited by 490

Circular RNAs as Promising Biomarkers: A Mini-Review

Abu, N., & Jamal, R. A. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00355 · Cited by 86

Long noncoding RNA turnover

Yoon, J., Kim, J., & Gorospe, M. (2015) · Biochimie · doi:10.1016/j.biochi.2015.03.001 · Cited by 84

Identification of differentially expressed circular RNAs in human colorectal cancer

Zhang, P., Zuo, Z., Shang, W., Wu, A., Bi, R., Wu, J., Li, S., Sun, X., & Jiang, L. (2017) · Tumor Biology · doi:10.1177/1010428317694546 · Cited by 82

CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p

Wang, S., Xue, X., Wang, R., Li, X., Li, Q., Wang, Y., Xie, P., Kang, Y.-H., Meng, R., & Feng, X. (2018) · Cancer Management and Research · doi:10.2147/cmar.s174778 · Cited by 82

Role of the ciRS-7/miR-7 axis in the regulation of proliferation, apoptosis and inflammation of chondrocytes induced by IL-1β.

Zhou, X.-D., Jiang, L.-F., Fan, G.-M., Yang, H.-Y., Wu, L.-D., Huang, Y., Xu, N.-W., & Li, J. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.03.037 · Cited by 71

The biogenesis and biological functions of circular RNAs and their molecular diagnostic values in cancers

Zhang, H., Shen, Y., Li, Z., Ruan, Y., Li, T., Xiao, B., & Sun, W. (2019) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.23049 · Cited by 80

Multifaceted p21 in carcinogenesis, stemness of tumor and tumor therapy

Xiao, B., Zhao, Y., Jia, X., Wu, J., Wang, Y., & Huang, F. (2020) · World Journal of Stem Cells · doi:10.4252/wjsc.v12.i6.481 · Cited by 79

CircRNA hsa_circ_0004585 as a potential biomarker for colorectal cancer

Tian, J., Xi, X., Wang, J., Yu, J., Huang, Q., Ma, R., Zhang, X., Hai, L., & Wang, L. (2019) · Cancer Management and Research · doi:10.2147/cmar.s199436 · Cited by 77

Circ‐RNF111 contributes to paclitaxel resistance in breast cancer by elevating E2F3 expression via miR ‐140‐5p

Zang, H.-L., Li, Y., Zhang, X., & Huang, G. (2020) · Thoracic Cancer · doi:10.1111/1759-7714.13475 · Cited by 76

Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3

Zhou, J., Zhang, W., Peng, F., Sun, J., He, Z., & Wu, S. (2018) · Cancer Management and Research · doi:10.2147/cmar.s155923 · Cited by 75

CircRNA fibroblast growth factor receptor 3 promotes tumor progression in non‐small cell lung cancer by regulating Galectin‐1‐AKT/ERK1/2 signaling

Qiu, B., Zhang, P., Xiong, D., Xu, J., Long, X., Zhu, S., Ye, X., Wu, Y., Pei, X., Zhang, X., et al. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27783 · Cited by 73

Design and application of circular RNAs with protein-sponge function

Schreiner, S., Didio, A., Hung, L.-H., & Bindereif, A. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa1085 · Cited by 74

Noncoding RNAs: New Players in Cancers

Chen, X., Fan, S., & Song, E. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-1498-7_1 · Cited by 73

Long non‐coding RNAs in corticogenesis: deciphering the non‐coding code of the brain

Aprea, J., & Calegari, F. (2015) · The EMBO Journal · doi:10.15252/embj.201592655 · Cited by 72

RNA Dynamics in Alzheimer’s Disease

Rybak‐Wolf, A., & Plass, M. (2021) · Molecules · doi:10.3390/molecules26175113 · Cited by 72

CircGFRA1 facilitates the malignant progression of HER‐2‐positive breast cancer via acting as a sponge of miR‐1228 and enhancing AIFM2 expression

Bazhabayi, M., Qiu, X., Li, X., Yang, A., Wen, W., Zhang, X., Xiao, X., He, R., & Liu, P. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16963 · Cited by 70

Circular RNAs: A Novel Player in Development and Disease of the Central Nervous System

Xie, L., Mao, M., Xiong, K., & Jiang, B. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00354 · Cited by 70

Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy

André, L. M., Ausems, C. R. M., Wansink, D. G., & Wieringa, B. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00368 · Cited by 68

The Role of Circular RNAs in Cerebral Ischemic Diseases: Ischemic Stroke and Cerebral Ischemia/Reperfusion Injury

Yang, J., Chen, M., Cao, R. Y., Li, Q. X., & Zhu, F. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1426-1_25 · Cited by 68

The Role of Circular RNAs in Immune-Related Diseases

Xie, R., Zhang, Y., Zhang, J., Li, J., & Zhou, X. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00545 · Cited by 69

CircMTO1 inhibits liver fibrosis via regulation of miR‐17‐5p and Smad7

Wang, W., Dong, R., Guo, Y. G., He, J., Shao, C., Yi, P., Yu, F., Gu, D., & Zheng, J. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14432 · Cited by 66

Circular RNAs signature predicts the early recurrence of stage III gastric cancer after radical surgery

Zhang, Y., Li, J., Yu, J., Liu, H., Shen, Z., Ye, G., Mou, T., Qi, X., & Li, G. (2017) · Oncotarget · doi:10.18632/oncotarget.15288 · Cited by 65

Novel RNA Modifications in the Nervous System: Form and Function

Satterlee, J. S., Basanta‐Sanchez, M., Blanco, S., Li, J. B., Meyer, K. D., Pollock, J. D., Sadri‐Vakili, G., & Rybak‐Wolf, A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3236-14.2014 · Cited by 63

FUS‐induced circular RNA ZNF609 promotes tumorigenesis and progression via sponging miR‐142‐3p in lung cancer

Liu, S., Yang, N., Jiang, X., Wang, J., Dong, J., & Gao, Y. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29481 · Cited by 61

Circ008913,viamiR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis

Xiao, T., Xue, J., Shi, M., Chen, C., Luo, F., Xu, H., Chen, X., Sun, B., Sun, Q., Yang, Q., et al. (2018) · Metallomics · doi:10.1039/c8mt00207j · Cited by 61

Non-coding RNA regulation of synaptic plasticity and memory: Implications for aging

Earls, L. R., Westmoreland, J. J., & Zakharenko, S. S. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.03.004 · Cited by 60

Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs

Pfafenrot, C., Schneider, T. P., Müller, C., Hung, L.-H., Schreiner, S., Ziebuhr, J., & Bindereif, A. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab1096 · Cited by 59

circ‐PKD2 inhibits carcinogenesis via the miR‐204‐3p/APC2 axis in oral squamous cell carcinoma

Gao, L., Zhao, C., Li, S., Dou, Z., Wang, Q., Liu, J., Ren, W., & Zhi, K. (2019) · Molecular Carcinogenesis · doi:10.1002/mc.23065 · Cited by 58

Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53

Zhang, X., Zhao, Y., Kong, P., Han, M., & Li, B. (2019) · Medical Science Monitor · doi:10.12659/msm.915926 · Cited by 58

CircRNA–miRNA interactions in atherogenesis

Tong, K.-L., Tan, K., Lim, Y., Tien, X.-Y., & Wong, P. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04455-8 · Cited by 59

Circular RNA expression profiles of mouse ovaries during postnatal development and the function of circular RNA epidermal growth factor receptor in granulosa cells

Jia, W., Xu, B., & Wu, J. (2018) · Metabolism · doi:10.1016/j.metabol.2018.04.002 · Cited by 58

RNA-seq of circular RNAs identified circPTPN22 as a potential new activity indicator in systemic lupus erythematosus

Miao, Q., Zhong, Z., Jiang, Z., Lin, Y., Ni, B., Yang, W., & Tang, J. (2019) · Lupus · doi:10.1177/0961203319830493 · Cited by 56

ciRS-7 targeting miR-135a-5p promotes neuropathic pain in CCI rats via inflammation and autophagy

Cai, W., Zhang, Y., & Su, Z. (2020) · Gene · doi:10.1016/j.gene.2020.144386 · Cited by 56

Circ_0001658 promotes the proliferation and metastasis of osteosarcoma cells via regulating miR‐382‐5p/YB‐1 axis

Wang, L., Wang, P., Su, X., & Zhao, B. (2019) · Cell Biochemistry and Function · doi:10.1002/cbf.3452 · Cited by 55

Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens

Zhang, X., Yan, Y., Lei, X., Li, A., Zhang, H., Dai, Z., Li, X., Chen, W., Lin, W., Chen, F., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.16442 · Cited by 55

Dysregulated circRNA_100876 suppresses proliferation of osteosarcoma cancer cells by targeting microRNA‐136

Jin, J. J., Chen, A., Qiu, W., Chen, Y., Li, Q., Zhou, X., & Jin, D. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28837 · Cited by 54

CRBPDL: Identification of circRNA-RBP interaction sites using an ensemble neural network approach

Niu, M., Zou, Q., & Lin, C. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009798 · Cited by 54

Regulation of microRNAs function by circular RNAs in human cancer

Han, C., Seebacher, N. A., Hornicek, F. J., Kan, Q., & Duan, Z. (2017) · Oncotarget · doi:10.18632/oncotarget.19930 · Cited by 55

The expression profile and clinical significance of circRNA0003906 in colorectal cancer

Zhuo, F., Lin, H., Chen, Z., Huang, Z., & Hu, J. (2017) · OncoTargets and Therapy · doi:10.2147/ott.s147378 · Cited by 52

CircRNA expression profile and functional analysis in testicular tissue of patients with non-obstructive azoospermia

Ge, P., Zhang, J., Zhou, L., Lv, M., Li, Y., Wang, J., & Zhou, D. (2019) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-019-0541-4 · Cited by 52

Viruses join the circular RNA world

Tan, K., & Lim, Y. (2020) · FEBS Journal · doi:10.1111/febs.15639 · Cited by 51

Circular RNAs: Functions and Prospects in Glioma

Zheng, H., Hu, S., Liu, Z., Wei-xin, S., Zhao, Y., & Li, M. (2018) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1211-2 · Cited by 49

Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression

Chen, S., Wu, W., Li, Q.-H., Xie, B., Shen, F., Du, Y., Zong, Z., Wang, L., Wei, X., & Zhao, Y. (2021) · Cell Death Discovery · doi:10.1038/s41420-020-00381-0 · Cited by 49

The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis

Xu, J., Du, W. W., Wu, N., Li, F., Li, X., Xie, Y., Wang, S., & Yang, B. B. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.03.007 · Cited by 50

Hsa_circ_0003998 Promotes Chemoresistance via Modulation of miR-326 in Lung Adenocarcinoma Cells

Yu, W., Peng, W., Sha, H., & Li, J. (2019) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504018x15420734828058 · Cited by 48

The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression

Yao, B., Zhu, S., Wei, X., Chen, M., Feng, Y., Li, Z., Xu, X., Zhang, Y., Wang, Y., Zhou, J., et al. (2022) · Molecular Cancer · doi:10.1186/s12943-022-01598-6 · Cited by 48

Hsa_circ_0003998 promotes cell proliferation and invasion by targeting miR-326 in non-small cell lung cancer

Yu, W., Jiang, H., Zhang, H., & Li, J. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s174750 · Cited by 47

Diabetic retinopathy: reversibility of epigenetic modifications and new therapeutic targets

Zhang, X., Zhao, L., Hambly, B. D., Bao, S., & Wang, K. (2017) · Cell & Bioscience · doi:10.1186/s13578-017-0167-1 · Cited by 47

The Novel Circular RNA Circ-PGAP3 Promotes the Proliferation and Invasion of Triple Negative Breast Cancer by Regulating the miR-330-3p/Myc Axis

He, D., Yang, X., Kuang, W., Huang, G., Liu, X., & Zhang, Y. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s274574 · Cited by 47

Exosomes in Immune Regulation

Schwarzenbach, H., & Gahan, P. B. (2021) · Non-Coding RNA · doi:10.3390/ncrna7010004 · Cited by 47

Circular RNAs in early brain development and their influence and clinical significance in neuropsychiatric disorders

Zhuo, C., Zhou, C., Zhu, J., Hou, W., Jiang, D., Tian, H., Wang, L., & Jia, F. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.268969 · Cited by 48

CircMAN1A2 is upregulated by Helicobacter pylori and promotes development of gastric cancer

Guo, R., Cui, X., Li, X., Zang, W., Chang, M., Sun, Z., Liu, Z., Sun, Y., Jia, J., & Li, W. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04811-y · Cited by 45

Identification of circular RNAs hsa_circ_0044235 and hsa_circ_0068367 as novel biomarkers for systemic lupus erythematosus

Luo, Q., Zhang, L., Li, X., Fu, B., Guo, Y., Huang, Z., & Li, J. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4302 · Cited by 45

Circulating plasma circular RNAs as novel diagnostic biomarkers for congenital heart disease in children

Wu, J., Li, J., Liu, H., Yin, J., Zhang, M., Yu, Z., & Miao, H. (2019) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22998 · Cited by 44

CircRNA_103809 Suppresses the Proliferation and Metastasis of Breast Cancer Cells by Sponging MicroRNA-532-3p (miR-532-3p)

Liu, M., Luo, C., Dong, J., Guo, J., Luo, Q., Ye, C., & Guo, Z. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00485 · Cited by 44

Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis

Deng, Y., Zhu, H., Xiao, L., Liu, C., & Meng, X. (2020) · Aging · doi:10.18632/aging.202234 · Cited by 44

circDiaph3 regulates rat vascular smooth muscle cell differentiation, proliferation, and migration

Xu, J., Chang, N., Rong, Z., Li, T., Xiao, L., Yao, Q., Jiang, R., & Jiang, J. (2018) · The FASEB Journal · doi:10.1096/fj.201800243rrr · Cited by 43

Circular RNAs as Potential Biomarkers and Therapeutic Targets for Metabolic Diseases

Zaiou, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-12668-1_10 · Cited by 44

Emerging roles of hsa_circ_0005075 targeting miR-431 in the progress of HCC

Li, M.-F., Li, Y., He, Y., Wang, Q., Zhang, Y., Li, X., Meng, X., Huang, C. Z., & Li, J. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.150 · Cited by 42

Significant function and research progress of biomarkers in gastric cancer (Review)

Ye, D., Xu, G., Ma, W., Li, Y., Luo, W., Xiao, Y., Liu, Y., & Zhang, Z. (2019) · Oncology Letters · doi:10.3892/ol.2019.11078 · Cited by 43

Downregulation of circular RNA circPVT1 restricts cell growth of hepatocellular carcinoma through downregulation of Sirtuin 7 via microRNA‐3666

Li, Y., Shi, H., Yuan, J., Qiao, L., Dong, L., & Wang, Y. (2020) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13273 · Cited by 42

Circular RNAs in depression: Biogenesis, function, expression, and therapeutic potential

Gan, H., Lei, Y., Yuan, N., Tang, K., Hao, W., Ma, Q., Wu, M., Zhou, X., Li, X., Huang, J., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111244 · Cited by 41

Circular RNAs as a New Field in Gene Regulation and their Implications in Translational Research

Vidal, A. F., Sandoval, G. T., de Magalhães, L. L., Santos, S. E., & Ribeiro‐dos‐Santos, Â. (2016) · Epigenomics · doi:10.2217/epi.16.3 · Cited by 41

Hsa_circ_0079530 promotes cell proliferation and invasion in non-small cell lung cancer

Li, J., Wang, J., Chen, Z., Chen, Y., & Jin, M. (2018) · Gene · doi:10.1016/j.gene.2018.04.059 · Cited by 41

The effect of Hsa_circ_0001451 in clear cell renal cell carcinoma cells and its relationship with clinicopathological features

Wang, G., Xue, W., Jian, W., Liu, P., Wang, Z., Wang, C., Li, H., Yu, Y., Zhang, D., & Zhang, C. L. (2018) · Journal of Cancer · doi:10.7150/jca.25902 · Cited by 40

Circular RNAs as potential biomarkers and therapeutics for cardiovascular disease

Wang, W., Wang, Y., Piao, H., Li, B., Huang, M., Zhu, Z., Li, D., Wang, T., Xu, R., & Liu, K. (2019) · PeerJ · doi:10.7717/peerj.6831 · Cited by 40

Screening of up‑ and downregulation of circRNAs in HBV‑related hepatocellular carcinoma by microarray

Cui, S., Qian, Z., Chen, Y., Li, L., Li, P., & Ding, H. (2017) · Oncology Letters · doi:10.3892/ol.2017.7265 · Cited by 39

Screening and bioinformatics analysis of circular RNA expression profiles in hepatitis B-related hepatocellular carcinoma

Wang, S., Cui, S., Zhao, W., Qian, Z., Liu, H., Chen, Y., Lv, F., & Ding, H.-G. (2018) · Cancer Biomarkers · doi:10.3233/cbm-170910 · Cited by 39

Circular RNA expression profiles during the differentiation of mouse neural stem cells

Yang, Q., Wu, J., Zhao, J., Xu, T., Zhao, Z., Song, X., & Han, P. (2018) · BMC Systems Biology · doi:10.1186/s12918-018-0651-1 · Cited by 39

Circular RNA circANKRD36 regulates Casz1 by targeting miR‐599 to prevent osteoarthritis chondrocyte apoptosis and inflammation

Zhou, J., Deng, S. H., Fang, H., Du, X., Peng, H., & Hu, Q. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15884 · Cited by 39

CircRNAs and RNA-Binding Proteins Involved in the Pathogenesis of Cancers or Central Nervous System Disorders

Ikeda, Y., Morikawa, S., Nakashima, M., Yoshikawa, S., Taniguchi, K., Sawamura, H., Suga, N., Tsuji, A., & Matsuda, S. (2023) · Non-Coding RNA · doi:10.3390/ncrna9020023 · Cited by 41

Single cell transcriptomics of noncoding RNAs and their cell‐specificity

Gawronski, K. A. B., & Kim, J. (2017) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1433 · Cited by 38

A universal approach to investigate circRNA protein coding function

Mo, D., Li, X., Raabe, C. A., Cui, D., Vollmar, J.-F., Rozhdestvensky, T. S., Skryabin, B. V., & Brosius, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-48224-y · Cited by 38

Circular RNA cMTO1 Promotes PTEN Expression Through Sponging miR-181b-5p in Liver Fibrosis

Jin, H. Z., Li, C., Dong, P., Huang, J., Yu, J., & Zheng, J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00714 · Cited by 38

CircETFA upregulates CCL5 by sponging miR-612 and recruiting EIF4A3 to promote hepatocellular carcinoma

Chen, L., Rong, D., Hui, B., He, X., Jiang, W., Xu, Y., Cao, H., Xu, Z., & Tang, W. (2021) · Cell Death Discovery · doi:10.1038/s41420-021-00710-x · Cited by 38

Unearthing Regulatory Axes of Breast Cancer circRNAs Networks to Find Novel Targets and Fathom Pivotal Mechanisms

Afzali, F., & Salimi, M. (2019) · Interdisciplinary Sciences Computational Life Sciences · doi:10.1007/s12539-019-00339-6 · Cited by 37

Engineering circular RNA regulators to specifically promote circular RNA production

Qi, Y., Han, W., Chen, D., Zhao, J., Bai, L., Huang, F., Dai, Z., Li, G., Chen, C., Zhang, W., et al. (2021) · Theranostics · doi:10.7150/thno.56990 · Cited by 37

Epigenetic Regulation of Ferroptosis-Associated Genes and Its Implication in Cancer Therapy

Pei, Y.-Z., Qian, Y., Wang, H., & Tan, L. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.771870 · Cited by 35

Hypothesis: Artifacts, Including Spurious Chimeric RNAs with a Short Homologous Sequence, Caused by Consecutive Reverse Transcriptions and Endogenous Random Primers

Peng, Z., Yuan, C., Zellmer, L., Liu, S., Xu, N., & Liao, D. J. (2015) · Journal of Cancer · doi:10.7150/jca.11997 · Cited by 37

RT-qPCR Detection of Senescence-Associated Circular RNAs

Panda, A. C., Abdelmohsen, K., & Gorospe, M. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6670-7_7 · Cited by 35

CircPSMC3 alleviates the symptoms of PCOS by sponging miR‐296‐3p and regulating PTEN expression

Liu, J., Ding, J., Qu, B., Liu, J., Song, X., Suo, Q.-L., Zhou, A., & Yang, J. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15747 · Cited by 35

Overexpression of circ_CELSR1 facilitates paclitaxel resistance of ovarian cancer by regulating miR-149-5p/SIK2 axis

Wei, S., Qi, L., & Wang, L. (2021) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000001058 · Cited by 35

Exosomal circRNAs: Emerging Players in Tumor Metastasis

Zhou, H., He, X., He, Y., Ou, C., & Cao, P. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.786224 · Cited by 35

Comparative analysis of circular RNA enrichment methods

Shi, H., Zhou, Y., Jia, E., Liu, Z., Pan, M., Bai, Y., Zhao, X., & Ge, Q. (2021) · RNA Biology · doi:10.1080/15476286.2021.2012632 · Cited by 35

CircFOXK2 promotes hepatocellular carcinoma progression and leads to a poor clinical prognosis via regulating the Warburg effect

Zheng, J., Yan, X., Lu, T., Song, W., Li, Y., Liang, J., Zhang, J., Cai, J., Sui, X. Y., Xiao, J., et al. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02624-1 · Cited by 35

Circular and Micro RNAs from Arabidopsis thaliana Flowers Are Simultaneously Isolated from AGO-IP Libraries

Capelari, É. F., da Fonseca, G. C., Guzmán, F., & Margis, R. (2019) · Plants · doi:10.3390/plants8090302 · Cited by 34

Cocaine induces differential circular RNA expression in striatum

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