The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway
Open accessAbstract
The intracellular retinoic acid-inducible gene I-like receptors (RLRs) sense viral ribonucleic acid and signal through the mitochondrial protein mitochondrial antiviral signalling (MAVS) to trigger the production of type I interferons and proinflammatory cytokines. In this study, we report that RLR activation promotes elongation of the mitochondrial network. Mimicking this elongation enhances signalling downstream from MAVS and favours the binding of MAVS to stimulator of interferon genes, an endoplasmic reticulum (ER) protein involved in the RLR pathway. By contrast, enforced mitochondrial fragmentation dampens signalling and reduces the association between both proteins. Our finding that MAVS is associated with a pool of mitofusin 1, a protein of the mitochondrial fusion machinery, suggests that MAVS is capable of regulating mitochondrial dynamics to facilitate the mitochondria-ER association required for signal transduction. Importantly, we observed that viral mitochondria-localized inhibitor of apoptosis, a cytomegalovirus (CMV) antiapoptotic protein that promotes mitochondrial fragmentation, inhibits signalling downstream from MAVS, suggesting a possible new immune modulation strategy of the CMV.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Multiple studies have demonstrated that mitochondrial fusion promotes, whereas mitochondrial fission inhibits RLR signaling (Castanier et al., 2010; Yasukawa et al., 2009; Zhao et al., 2012).”
From Mitochondria in the Regulation of Innate and Adaptive Immunity (2015) · cites this paper as Castanier et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Pathogen Recognition and Innate Immunity
Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 12,401
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Ishikawa, H., & Barber, G. N. (2008) · Nature · doi:10.1038/nature07317 · Cited by 3,576
Seth, R. B., Sun, L., Ea, C.-K., & Chen, Z. J. (2005) · Cell · doi:10.1016/j.cell.2005.08.012 · Cited by 3,329
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
Kawai, T., Takahashi, K., Sato, S., Coban, C., Kumar, H., Kato, H., Ishii, K. J., Takeuchi, O., & Akira, S. (2005) · Nature Immunology · doi:10.1038/ni1243 · Cited by 2,562
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
Meylan, E., Curran, J., Hofmann, K., Moradpour, D., Binder, M., Bartenschlager, R., & Tschopp, J. (2005) · Nature · doi:10.1038/nature04193 · Cited by 2,401
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
Chan, D. C. (2006) · Cell · doi:10.1016/j.cell.2006.06.010 · Cited by 1,987
Mitochondria: More Than Just a Powerhouse
McBride, H. M., Neuspiel, M., & Wasiak, S. (2006) · Current Biology · doi:10.1016/j.cub.2006.06.054 · Cited by 1,985
VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling
Xu, L., Wang, Y., Han, K.-J., Li, L., Zhai, Z., & Shu, H. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.08.014 · Cited by 1,849
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Zhong, B., Yang, Y., Li, S., Wang, Y., Li, Y., Diao, F., Lei, C., He, X., Zhang, L., Tien, P., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.09.003 · Cited by 1,514
RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway
Chiu, Y., MacMillan, J. B., & Chen, Z. J. (2009) · Cell · doi:10.1016/j.cell.2009.06.015 · Cited by 1,185
Cited by
Sorted by citations
Items 201–300 of 316
Gao, X., Chen, D., Hu, X., Zhou, Y., Wang, Y., Wu, C., Chen, J., Wang, Y., Pei, R., & Chen, X. (2018) · Journal of Innate Immunity · doi:10.1159/000489832 · Cited by 19
Genovese, I., Vezzani, B., Danese, A., Modesti, L., Vitto, V. A. M., Corazzi, V., Pelucchi, S., Pinton, P., & Giorgi, C. (2020) · Cell Calcium · doi:10.1016/j.ceca.2020.102308 · Cited by 21
Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner
Ferreira, A., Gouveia, A., Magalhães, A. C., Valença, I., Marques, M., Kagan, J. C., & Ribeiro, D. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.871977 · Cited by 19
Gregorczyk-Zboroch, K. P., Wyżewski, Z., Szczepanowska, J., Toka, F. N., Mielcarska, M. B., Bossowska-Nowicka, M., Gieryńska, M. M., Boratyńska-Jasińska, A., Struzik, J., Niemiałtowski, M., et al. (2018) · Viruses · doi:10.3390/v10050266 · Cited by 19
An Overview of Current Knowledge of Deadly CoVs and Their Interface with Innate Immunity
Zhang, Y., Gargan, S., Lu, Y., & Stevenson, N. J. (2021) · Viruses · doi:10.3390/v13040560 · Cited by 17
Connection Between HIV and Mitochondria in Cardiovascular Disease and Implications for Treatments
Hinton, A. O., Jr., N′jai, A. U., Vue, Z., & Wanjalla, C. N. (2024) · Circulation Research · doi:10.1161/circresaha.124.324296 · Cited by 20
The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein
Li, S., Liu, S., Dai, Z., Zhang, Q., Xu, Y., Chen, Y., Jiang, Z., Huang, W., & Sun, H. (2021) · Scientific Reports · doi:10.1038/s41598-021-93430-2 · Cited by 17
Mitochondria Drive Immune Responses in Critical Disease
Tiwari‐Heckler, S., Robson, S. C., & Longhi, M. S. (2022) · Cells · doi:10.3390/cells11244113 · Cited by 18
Flaviviruses manipulate mitochondrial processes to evade the innate immune response
Boytz, R., Keita, K., Pawlak, J. B., & Laurent-Rolle, M. (2024) · npj Viruses · doi:10.1038/s44298-024-00057-x · Cited by 17
Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization
Nobre, L., Wise, D., Ron, D., & Volmer, R. (2015) · PLOS ONE · doi:10.1371/journal.pone.0136883 · Cited by 12
Caspase-8 and FLIP Regulate RIG-I/MDA5-induced Innate Immune Host Responses to Picornaviruses
Buskiewicz, I. A., Koenig, A., Huber, S. A., & Budd, R. C. (2012) · Future Virology · doi:10.2217/fvl.12.115 · Cited by 16
Tajpara, P., Schuster, C., Schön, E., Kienzl, P., Vierhapper, M. F., Mildner, M., & Elbe‐Bürger, A. (2018) · The FASEB Journal · doi:10.1096/fj.201701090r · Cited by 16
dos Reis, L. M., Berçot, M. R., Castelucci, B. G., Martins, A. J. E., Castro, G., & Moraes‐Vieira, P. M. (2023) · Viruses · doi:10.3390/v15020525 · Cited by 17
Hofstadter, W. A., Cook, K. C., Tsopurashvili, E., Gebauer, R., Pražák, V., Machala, E. A., Park, J. W., Grünewald, K., Quemin, E. R. J., & Cristea, I. M. (2024) · Nature Communications · doi:10.1038/s41467-024-51680-4 · Cited by 14
Brucella abortus DNA is a major bacterial agonist to activate the host innate immune system
Campos, P. C., Gomes, M. T. R., Guimarães, G. R., Franco, M. M. S. C., Marim, F. M., & Oliveira, S. C. (2014) · Microbes and Infection · doi:10.1016/j.micinf.2014.08.010 · Cited by 15
Sato, Y., Yoshino, H., Kashiwakura, I., & Tsuruga, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010420 · Cited by 15
The critical roles of STING in mitochondrial homeostasis
Zou, S., Wang, B., Yi, K., Su, D., Chen, Y., Li, N., & Geng, Q. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115938 · Cited by 17
Lara-Hernández, I., Muñoz-Escalante, J. C., Bernal‐Silva, S., Noyola, D. E., Wong‐Chew, R. M., Comas‐García, A., & Comas‐García, M. (2023) · Viruses · doi:10.3390/v15071518 · Cited by 13
The Gut-Brain Axis in Alzheimer’s and Parkinson’s Diseases: The Catalytic Role of Mitochondria
Candeias, E., Pereira-Santos, A. R., Empadinhas, N., Cardoso, S. M., & Esteves, A. R. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240524 · Cited by 16
Modulation of Mitochondria During Viral Infections
Reshi, L., Wang, H., & Hong, J. (2018) · InTech eBooks · doi:10.5772/intechopen.73036 · Cited by 13
On the offense and defense: mitochondrial recovery programs amidst targeted pathogenic assault
Mahmud, S. A., Qureshi, M. A., & Pellegrino, M. W. (2021) · FEBS Journal · doi:10.1111/febs.16126 · Cited by 13
Huang, K., Pei, S., Sun, Y., Xu, X., Fang, Y., Lai, M., Xiang, G., Feng, X., & Zheng, X. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04615-22 · Cited by 13
Yan, X., Zhao, X., Zhou, M., Sun, Y., & Xu, T. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.858179 · Cited by 12
Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections
Ren, S., Ding, C., & Sun, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103689 · Cited by 13
Superresolution imaging of viral protein trafficking
Colberg‐Poley, A. M., Patterson, G. H., Salka, K., Bhuvanendran, S., Yang, D. X., & Jaiswal, J. K. (2015) · Medical Microbiology and Immunology · doi:10.1007/s00430-015-0395-0 · Cited by 12
Li, W., Wang, X., Lin, Y., Zhou, Y., Li, J., Zhang, X.-Y., & Chen, X. (2023) · Marine Life Science & Technology · doi:10.1007/s42995-023-00189-8 · Cited by 11
Małkowska, P., & Niedźwiedzka‐Rystwej, P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1010635 · Cited by 11
Supramolecular organizing centers at the interface of inflammation and neurodegeneration
Sušjan, P., Ramuta, T. Ž., Boršić, E., Orehek, S., & Hafner‐Bratkovič, I. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.940969 · Cited by 11
Mao, X., Meng, G., Li, M., & Wei, J. (2014) · DNA and Cell Biology · doi:10.1089/dna.2014.2567 · Cited by 10
Allen, C. H., Ahmed, D., Raiche-Tanner, O., Chauhan, V., Mostaço-Guidolin, L. B., Cassol, E., & Murugkar, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-93043-9 · Cited by 9
Mitochondrial Dynamics and Apoptosis
Harwig, M. C., & Youle, R. J. (2011) · Springer eBooks · doi:10.1007/978-94-007-1291-1_4 · Cited by 9
Intricacy of Mitochondrial Dynamics and Antiviral Response During RNA Virus Infection
Singh, S., Dirani, K., & Kumar, A. (2022) · Frontiers in Virology · doi:10.3389/fviro.2022.918806 · Cited by 8
Innate sensing and cellular metabolism: role in fine tuning antiviral immune responses
Ahmed, D., Daraawi, M. A., & Cassol, E. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiac011 · Cited by 8
Curto, P., Santa, C., Cortes, L., Manadas, B. J., & Simões, I. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00814-21 · Cited by 8
Zhou, J., Xi, Y., Wu, T., Zeng, X., Yuan, J., Peng, L., Fu, H., & Zhou, C. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1506292 · Cited by 10
Natural products alleviate atrial fibrillation by modulating mitochondrial quality control
Ge, T., Zou, R., Zhang, M., Hu, J., He, K., Li, G., Zhang, T., & Fan, X. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156555 · Cited by 9
Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens
Paul, P., & Tiwari, B. (2023) · Virulence · doi:10.1080/21505594.2023.2265095 · Cited by 7
The diverse roles of peroxisomes in the interplay between viruses and mammalian cells
Jiang, H., Nair, V., Sun, Y., & Ding, C. (2023) · Antiviral Research · doi:10.1016/j.antiviral.2023.105780 · Cited by 7
Non-apoptotic functions of cell death effectors in inflammation and innate immunity
Morizot, A., & Saleh, M. (2012) · Microbes and Infection · doi:10.1016/j.micinf.2012.06.005 · Cited by 7
CK2 induced RIG-I drives metabolic adaptations in IFNγ-treated glioma cells
Ghildiyal, R., & Sen, E. (2015) · Cytokine · doi:10.1016/j.cyto.2015.10.009 · Cited by 7
Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production
Yang, Y. S., Xiong, S., Cai, B., Luo, H. B., Dong, E., Li, Q., Ji, G., Zhao, C., Wen, Y., Wei, Y., et al. (2017) · Scientific Reports · doi:10.1038/srep44303 · Cited by 8
Interruption of mitochondrial symbiosis is associated with the development of osteoporosis
Zhang, H., Zhao, R. Z., Wang, X., Qi, Y., Sandai, D. A., Wang, W., Song, Z., & Liang, Q. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1488489 · Cited by 7
Cheramangalam, R. N., Anand, T., Pandey, P., Balasubramanian, D., Varghese, R., Singhal, N., Nagarkar-Jaiswal, S., & Jaiswal, M. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010493 · Cited by 6
Yu, X., Jiang, H., Li, J., Ding, J., Chen, K., Ding, Z., & Xu, X. (2023) · Veterinary Microbiology · doi:10.1016/j.vetmic.2023.109973 · Cited by 6
The SARS-CoV2 and mitochondria: the impact on cell fate.
Madeddu, E., Maniga, B., Zaffanello, M., Fanos, V., & Marcialis, A. (2022) · PubMed Central · doi:10.23750/abm.v93i2.10327 · Cited by 6
DRP1 Association in Inflammation and Metastasis: A Review
Nandan, P. K., Job, A. T., & Tamizhselvi, R. (2024) · Current Drug Targets · doi:10.2174/0113894501304751240819111831 · Cited by 6
Suicide watch: how cytomegalovirus interferes with the cell-death pathways of infected cells
Andoniou, C. E. (2010) · Tissue Antigens · doi:10.1111/j.1399-0039.2010.01494.x · Cited by 6
Do mitochondria have an immune system?
Popkov, V. A., Zorova, L. D., Korvigo, I. O., Silachev, D. N., Jankauskas, S. S., Babenko, V. A., Pevzner, I. B., Danilina, T. I., Zorov, S. D., Plotnikov, E. Y., et al. (2016) · Biochemistry (Moscow) · doi:10.1134/s0006297916100217 · Cited by 5
Innate Immune Priming by cGAS as a Preparatory Countermeasure Against RNA Virus InfectionPreprint
Parker, M. T., Gopinath, S., Perez, C. E., Linehan, M. M., Crawford, J. M., Iwasaki, A., & Lindenbach, B. D. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/434027 · Cited by 6
Abbas, R., & Ghssein, G. (2025) · Clinical bioenergetics · doi:10.3390/clinbioenerg1020008 · Cited by 6
Qu, Y., Ren, S.-H., Liao, Y., Qiu, X., Tan, L., Song, C.-P., Sun, Y.-J., & Ding, C. (2026) · Autophagy · doi:10.1080/15548627.2026.2624746 · Cited by 5
Weber, L., & Vièyres, G. (2022) · Cells · doi:10.3390/cells11193149 · Cited by 5
Prasad, K. P., Krishnan, R., Uthaman, S. K., Jeena, K., & Kumar, P. V. (2024) · Fish Pathology · doi:10.3147/jsfp.59.39 · Cited by 5
Cellular Titanomachy: Viral Forces Clash with Mitochondrial Power
Defresne, T., Suspène, R., & Vartanian, J. (2025) · Annual Review of Virology · doi:10.1146/annurev-virology-092623-090901 · Cited by 5
Park, J. W., Tyl, M. D., & Cristea, I. M. (2023) · Biomolecules · doi:10.3390/biom13050869 · Cited by 4
Chivé, C., Eon-Bertho, A., Martίn-Faivre, L., Tête, A., Izabelle, C., Sallenave, J., García-Verdugo, I., & Baeza‐Squiban, A. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126687 · Cited by 5
MAVS Positively Regulates Mitochondrial Integrity and Metabolic Fitness in B Cells
Wang, H., Sun, W., Traba, J., Wu, J., Qi, C., Amo, L., Kole, H. K., Scott, B. L., Singh, K., Sack, M. N., et al. (2023) · ImmunoHorizons · doi:10.4049/immunohorizons.2300038 · Cited by 4
Gregorczyk-Zboroch, K. P., Szulc‐Dąbrowska, L., Pruchniak, P., Gieryńska, M. M., Mielcarska, M. B., Biernacka, Z., Wyżewski, Z., Lasocka, I., Świtlik, W. Z., Szepietowska, A., et al. (2024) · Pathogens · doi:10.3390/pathogens13090717 · Cited by 4
Thomas, D. W., Yang, J., Cho, S. J., & Stout-Delgado, H. W. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103329 · Cited by 4
Metabolic Regulation of Immunity
Wang, R., Wang, T., & Tait, S. W. G. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-31696-5.00020-6 · Cited by 4
The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Madsen, H. B., Pease, L. I., Scanlan, R.-L., Akbari, M., Rasmussen, L. J., Shanley, D. P., & Bohr, V. A. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1290681 · Cited by 4
Osei, D., Baumgart‐Vogt, E., Ahlemeyer, B., & Herden, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031849 · Cited by 4
Effect of infectious bursal disease virus infection on energy metabolism in embryonic chicken livers
Li, Y., Yang, D., Jia, Y., He, L., Li, J., Chen, Y., Liao, C., Yu, Z., & Zhang, C. (2019) · British Poultry Science · doi:10.1080/00071668.2019.1647586 · Cited by 4
Mitochondria and Antiviral Immunity
Thomas, S., & Gale, M. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3612-0_10 · Cited by 4
Hou, J., Lu, P., Cui, X., Luo, L., Pan, Q., & Li, J. (2026) · Advanced Science · doi:10.1002/advs.202513442 · Cited by 3
Understanding the mechanisms of mitochondrial rewiring during viral infections
Lopez-Nieto, M., & Locker, N. (2025) · Journal of General Virology · doi:10.1099/jgv.0.002128 · Cited by 6
Torices, S., Moreno, T., Osborne, O., Ramaswamy, S., Naranjo, O., Téglás, T., Park, M., Sun, E., & Toborek, M. J. (2025) · Brain · doi:10.1093/brain/awaf262 · Cited by 8
Zhao, F., & Fessler, M. B. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0373-3 · Cited by 3
Wang, L., & Nomura, M. (2015) · Genomics Data · doi:10.1016/j.gdata.2015.07.021 · Cited by 3
Mitochondrial function and dysfunction in innate immunity
Oliva, A., Meroño, C., & Traba, J. (2022) · Current Opinion in Physiology · doi:10.1016/j.cophys.2022.100571 · Cited by 3
Szulc‐Dąbrowska, L., Wyżewski, Z., Gregorczyk-Zboroch, K. P., Toka, F. N., Szczepanowska, J., Struzik, J., Nowak-Życzyńska, Z., Gieryńska, M. M., & Niemiałtowski, M. (2020) · Acta Virologica · doi:10.4149/av_2020_305 · Cited by 3
Arenavirus nucleoprotein localizes to mitochondriaPreprint
Baggio, F., Hetzel, U., Nufer, L., Kipar, A., & Hepojoki, J. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.06.370825 · Cited by 3
Shaping Viral Infection Outcomes via Organelle Remodeling
Hofstadter, W. A., & Cristea, I. M. (2025) · Annual Review of Virology · doi:10.1146/annurev-virology-092623-094221 · Cited by 3
Nishigori, M., Hirata, S., Kosako, H., Ichinohe, T., Nolte, H., Riemer, J., Langer, T., & Koshiba, T. (2026) · The EMBO Journal · doi:10.1038/s44318-026-00734-y · Cited by 4
Guimarães, E. S., Gomes, M. T. R., Moraes‐Vieira, P. M., & Oliveira, S. C. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf198 · Cited by 2
Torices, S., Moreno, T., Ramaswamy, S., Naranjo, O., Téglás, T., Osborne, O., Park, M., Sun, E., & Toborek, M. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.07.598027 · Cited by 2
Ahmed, D., Slade, A., Fatica, T., Baird, S. D., Bhattarai, K., Atallah, T., Cassol, E., & Holčík, M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1497766 · Cited by 1
Age-Related Changes in Immune Regulation by Noncoding RNAs
Wang, W., Qian, F., & Montgomery, R. R. (2019) · Springer eBooks · doi:10.1007/978-3-319-99375-1_109 · Cited by 1
Castillo‐Galán, S., Grünenwald, F., Hidalgo, Y., Cárdenas, C., Cádiz, M. I., Alcayaga‐Miranda, F., Khoury, M., & Cuenca, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104686 · Cited by 1
Mitochondrial Dynamics and Cellular Antiviral Immunity
Koshiba, T., & Kuboyama, M. (2011) · Seibutsu Butsuri · doi:10.2142/biophys.51.174 · Cited by 1
Metabolic Regulation of Antiviral Immune Responses in Macrophages
Ahmed, D. (2021) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2021-14431 · Cited by 1
Ahmed, D., Daraawi, M. A., Humphrey, A., Abdo, O., Roy, D., Sheridan, M.-E., Versey, Z., Mejlaoui, R., Jaworski, A. F., Edwards, A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.03.691914 · Cited by 1
CHARACTERIZATION OF THE ROLES OF TWO REGULATORS OF VIRUS INFECTION: GP78 AND BPIFB3
Jacobs, J. L. (2014) · D-Scholarship@Pitt (University of Pittsburgh)
Innate Immune Recognition of RNA-virus infection in human macrophages
Kerminen, J. (2011) · Työväentutkimus Vuosikirja
Brubaker, S. W. (2014) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Review Article Mitochondria and antiviral innate immunity
Koshiba, T., Bashiruddin, N. K., & Shun-ichiro, K. (2011)
Characterization of MAVS-dependent antiviral signaling
der Abteilung, A., München, L.-M.-U., & Reincke, M. (2014)
Influenza A virus modulation of mitochondria dynamics
Veríssimo, M. I. M. (2016) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
de Chassey, B., & Morel, É. (2021) · médecine/sciences · doi:10.1051/medsci/2021171
Age-Related Changes in Immune Regulation by Noncoding RNAs
Wang, W., Qian, F., & Montgomery, R. R. (2017) · Springer eBooks · doi:10.1007/978-3-319-64597-1_109-1
Cheramangalam, R. N., Anand, T., Pandey, P., Balasubramanian, D., Varghese, R., Singhal, N., Nagarkar-Jaiswal, S., & Jaiswal, M. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.24.513457
Osei, D., Baumgart‐Vogt, E., Ahlemeyer, B., & Herden, C. (2023) · Research Square · doi:10.21203/rs.3.rs-3331286/v1
Development and Application of a Multimodal Coherent Raman Scattering Microscope
Allen, C. H. (2024) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2024-15880
Drp1 promotes vascular smooth muscle cell death via adverse mitochondrial dynamicsPreprint
Patel, V. B., Jadli, A. S., Meechem, M. B., Gomes, K., Mackay, C. D. A., Edalat, P., & Palma, C. D. (2025) · Research Square · doi:10.21203/rs.3.rs-5968820/v1
MAVS Safeguards Mitochondrial Integrity to Drive a Potent Intrinsic Antiviral ProgramPreprint
Sah, V., Potharaju, P. S., Nair, K. S., Sahoo, P. P., Pooja, R. A., Basu, D., Tandel, D., Varadarajan, K. S., Chauhan, S., Patel, A. B., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.28.651145
DPV UL38 stabilizes MFN2 to subvert MAVS-mediated antiviral immunity in ducks
Tian, B., Wang, X., He, S., Cai, D., Tian, Y., Wang, M., Jia, R., Chen, S., Zhu, D., Liu, M., et al. (2025) · Veterinary Microbiology · doi:10.1016/j.vetmic.2025.110721
Metadata
- Authors
- Castanier, C., Garcin, D., Vazquez, A., & Arnoult, D.
- Affiliations
- Université Paris-Sud (FR)
- University of Geneva (CH)
- Corresponding author
- Arnoult, Damien
- Venue
- The EMBO Reports
- Published
- 2009-12-18
- Volume
- 11
- Issue
- 2
- Pages
- 133-138
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- PMC
- PMC2828750
- OpenAlex
- W1993205112
- Cited by
- 316
- References
- 17
- Citations by year
- 2026: 10 · 2025: 18 · 2024: 14 · 2023: 20 · 2022: 19 · 2021: 26 · 2020: 27 · 2019: 23 · 2018: 19 · 2017: 20 · 2016: 16 · 2015: 17 · 2014: 22 · 2013: 11 · 2012: 20
- FWCI
- 7.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- EMBO Reports (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › interferon and immune responses
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Keywords
- mitochondrial dynamics, RIG-I-like receptors, MAVS, mitochondrial fusion, mitofusin 1, mitochondrial fragmentation, STING, type I interferon signaling, viral RNA sensing, cytomegalovirus, immune evasion, antiviral innate immunity
- MeSH terms
- STING Protein, Antiviral Agents, Cells, Cultured, HeLa Cells, Humans, Immunity, Innate, Membrane Proteins, Mitochondria, Protein Binding, Virus Diseases, Signal Transduction, Receptors, Retinoic Acid, Mitochondrial Proteins, Organelle Shape, Organelle Size
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review