Cited by 372Dermatology and Skin DiseasesAdvancements in Transdermal Drug DeliveryContact Dermatitis and Allergies

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Changes in the Ceramide Profile of Atopic Dermatitis Patients

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Ishikawa, Junko, Narita, Hirofumi, Kondo, Naoki, Hotta, Mitsuyuki, Takagi, Yutaka, Masukawa, Yoshinori, Kitahara, Takashi, Takema, Yoshinori, Koyano, Satomi, Yamazaki, Soji, Hatamochi, Atsushi·2010·Journal of Investigative Dermatology

DOI 10.1038/jid.2010.161

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Crossref · 10.1038/jid.2010.161

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14 of 14 references verified0 citation errors · 0 not checkable

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Epidermal Lipids, Barrier Function, and Desquamation
Elias, P. M. (1983) · Journal of Investigative Dermatology · doi:10.1038/jid.1983.12 · Cited by 1,356
Decreased Level of Ceramides in Stratum Corneum of Atopic Dermatitis: An Etiologic Factor in Atopic Dry Skin?
Imokawa, G., Abe, A., Jin, K., Higaki, Y., Kawashima, M., & Hidano, A. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470233 · Cited by 1,040
Ceramide and cholesterol composition of the skin of patients with atopic dermatitis
Nardo, A. D. (1998) · Acta Dermato Venereologica · doi:10.1080/00015559850135788 · Cited by 483
Ceramide composition of the psoriatic scale
Motta, S., Monti, M., Sesana, S., Caputo, R., Carelli, S., & Ghidoni, R. (1993) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(93)90135-n · Cited by 435
Characterization of overall ceramide species in human stratum corneum
Masukawa, Y., Narita, H., Shimizu, E., Kondo, N., Sugai, Y., Oba, T., Homma, R., Ishikawa, J., Takagi, Y., Kitahara, T., et al. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800014-jlr200 · Cited by 322
Self-citation
Stratum corneum lipid abnormalities in atopic dermatitis
Yamamoto, A., Serizawa, S., Ito, M., & Sato, Y. (1991) · Archives of Dermatological Research · doi:10.1007/bf01106105 · Cited by 272
Deficiency of Epidermal Protein-Bound ω-Hydroxyceramides in Atopic Dermatitis
Macheleidt, O., Sandhoff, K., & Kaiser, H. W. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01833.x · Cited by 236
Comprehensive quantification of ceramide species in human stratum corneum
Masukawa, Y., Narita, H., Sato, H., Naoe, A., Kondo, N., Sugai, Y., Oba, T., Homma, R., Ishikawa, J., Takagi, Y., et al. (2009) · Journal of Lipid Research · doi:10.1194/jlr.d800055-jlr200 · Cited by 228
Self-citation
Two Ceramide Subfractions Detectable in Cer(AS) Position by HPTLC in Skin Surface Lipids of Non-Lesional Skin of Atopic Eczema
Bleck, O., Abeck, D., Ring, J., Hoppe, U., Vietzke, J., Wolber, R., Brandt, O., & Schreiner, V. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00809.x · Cited by 135
Ceramide profiles of the uninvolved skin in atopic dermatitis and psoriasis are comparable to those of healthy skin
Farwanah, H., Raith, K., Neubert, R. H. H., & Wohlrab, J. (2005) · Archives of Dermatological Research · doi:10.1007/s00403-005-0551-2 · Cited by 123

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Atopic dermatitis
Weidinger, S., & Novak, N. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00149-x · Cited by 1,908
Atopic dermatitis
Weidinger, S., Beck, L. A., Bieber, T., Kabashima, K., & Irvine, A. D. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0001-z · Cited by 1,549
The important role of stratum corneum lipids for the cutaneous barrier function
van Smeden, J., Janssens, M., Gooris, G. S., & Bouwstra, J. A. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.11.006 · Cited by 549
Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients
Janssens, M., van Smeden, J., Gooris, G. S., Bras, W., Portale, G., Caspers, P. J., Vreeken, R. J., Hankemeier, T., Kezic, S., Wolterbeek, R., et al. (2012) · Journal of Lipid Research · doi:10.1194/jlr.p030338 · Cited by 488
TNF-α and Th2 Cytokines Induce Atopic Dermatitis–Like Features on Epidermal Differentiation Proteins and Stratum Corneum Lipids in Human Skin Equivalents
Danso, M. O., van Drongelen, V., Mulder, A. A., van Esch, J., Scott, H. C., van Smeden, J., Ghalbzouri, A. E., & Bouwstra, J. A. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.83 · Cited by 327

See all 372

Ceramide Plays a Major Role in the Pathogenesis of Atopic Dermatitis.
Ishida, K. (2019) · Data Archiving and Networked Services (DANS) · doi:10.17632/9443yrtkn9
Ceramide and cholesterol composition of the skin of patients with atopic dermatitis
Nardo, A. D. (1998) · Acta Dermato Venereologica · doi:10.1080/00015559850135788 · Cited by 483
Relationship of ceramide–, and free fatty acid–cholesterol ratios in the stratum corneum with skin barrier function of normal, atopic dermatitis lesional and non-lesional skins
Joo, K., Hwang, J.-H., Bae, S., Nahm, D., Park, H., Ye, Y., & Lim, K. (2014) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2014.10.001 · Cited by 57
Decreased Level of Ceramides in Stratum Corneum of Atopic Dermatitis: An Etiologic Factor in Atopic Dry Skin?
Imokawa, G., Abe, A., Jin, K., Higaki, Y., Kawashima, M., & Hidano, A. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470233 · Cited by 1,040
Decrease of Ceramides with Very Long–Chain Fatty Acids and Downregulation of Elongases in a Murine Atopic Dermatitis Model
Park, Y.-H., Jang, W.-H., Seo, J. A., Park, M., Lee, T. R., Park, Y.-H., Kim, D. K., & Lim, K. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.333 · Cited by 61
Stratum corneum lipid abnormalities in atopic dermatitis
Yamamoto, A., Serizawa, S., Ito, M., & Sato, Y. (1991) · Archives of Dermatological Research · doi:10.1007/bf01106105 · Cited by 272
Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role
Imokawa, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041613 · Cited by 29
Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype
Ishida, K., Takahashi, A., Bito, K., Draelos, Z. D., & Imokawa, G. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.01.014 · Cited by 29
The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis
Nugroho, W. T., Sawitri, S., Astindari, A., Utomo, B., Listiawan, M. Y., Ervianti, E., & Astari, L. (2023) · Indian Journal of Dermatology · doi:10.4103/ijd.ijd_991_22 · Cited by 24
Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management
Sakai, T. (2025) · The Journal of Dermatology · doi:10.1111/1346-8138.70098 · Cited by 6

Authors: Ishikawa, J., Narita, H., Kondo, N., Hotta, M., Takagi, Y., Masukawa, Y., Kitahara, T., Takema, Y., Koyano, S., Yamazaki, S., & Hatamochi, A.
Affiliations: Kao Corporation (Japan) (JP)
Dokkyo University (JP)
Corresponding author: Ishikawa, Junko
ORCID: Ishikawa, Junko
Kondo, Naoki
Hotta, Mitsuyuki
Takagi, Yutaka
Venue: Journal of Investigative Dermatology
Publisher: Elsevier BV
Published: 2010-10
Volume: 130
Issue: 10
Pages: 2511-2514
ISSN: 0022-202X (ISSN-L)
DOI: 10.1038/jid.2010.161
OpenAlex: W2028086345
Cited by: 372
References: 14
Citations by year: 2026: 17 · 2025: 29 · 2024: 31 · 2023: 32 · 2022: 30 · 2021: 24 · 2020: 26 · 2019: 30 · 2018: 34 · 2017: 23 · 2016: 27 · 2015: 9 · 2014: 18 · 2013: 19 · 2012: 9
FWCI: 15.96
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1888 d)
Locations: Journal of Investigative Dermatology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
Keywords: atopic dermatitis, ceramide, stratum corneum, transepidermal water loss, skin barrier function, skin barrier dysfunction, dry skin, epidermal lipids, healthy controls comparison, ceramide metabolism, ceramide transport
MeSH terms: Ceramides, Dermatitis, Atopic, Epidermis, Humans

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Changes in the Ceramide Profile of Atopic Dermatitis Patients

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