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Cited by 502

The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.

Ionizing Radiation: The Good, the Bad, and the Ugly

Open access
Ryan, Julie L.·2012·Journal of Investigative Dermatology

Abstract

Skin changes from ionizing radiation have been scientifically documented since 1902 (Hymes et al., 2006). Ionizing radiation is a widely accepted form of treatment for various types of cancer. Despite the technological advances, radiation skin injury remains a significant problem. This injury, often referred to as radiation dermatitis, occurs in about 95% of patients receiving radiation therapy for cancer and ranges in severity from mild erythema to moist desquamation and ulceration (McQuestion, 2011; Salvo et al., 2010). Ionizing radiation is not only a concern for cancer patients, but also a public health concern due to the potential for and reality of a nuclear and/or radiological event. Recently, the United States has increased efforts to develop medical countermeasures to protect against radiation toxicities from acts of bioterrorism, as well as cancer treatment. Management of radiation dermatitis would improve the therapeutic benefit of radiation therapy for cancer and potentially the mortality expected in any “dirty bomb” attack (Benderitter et al., 2010; Muller and Meineke, 2010). Currently, there is no effective treatment to prevent or mitigate radiation skin injury. This review summarizes “the good, the bad and the ugly” of current and evolving knowledge regarding mechanisms of and treatments for radiation skin injury.

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Metadata

Authors
Ryan, J. L.
Venue
Journal of Investigative Dermatology
Publisher
Elsevier BV
Published
2012-03
Volume
132
Issue
3
Pages
985-993
ISSN
0022-202X (ISSN-L)
OpenAlex
W2015571719
Cited by
502
References
71
FWCI
13.35
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Ionizing Radiation: The Good, the Bad, and the Ugly. https://app.cochat.ai/papers/10.1038/jid.2011.411
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Ryan, J. L. (2012). Ionizing Radiation: The Good, the Bad, and the Ugly. Journal of Investigative Dermatology. https://doi.org/10.1038/jid.2011.411

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.