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Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions

Yuan, Q., Wang, Y., Song, R., Hou, X., Yu, K., Zheng, J., Zhang, J., Pu, X., Han, J., & Zong, L. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00225 · Cited by 23 · see citing works

Eplerenone nanoemulsions for treatment of hypertension. Part I: Experimental design for optimization of formulations and physical characterization

Özdemir, S., Çelik, B., Acar, E. T., Duman, G., & Üner, M. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.03.011 · Cited by 23 · see citing works

A quality by design approach for optimization of Lecithin/Span® 80 based nanoemulsions loaded with hydrophobic drugs

Real, D. A., Hoffmann, S. R. K., Leonardi, D., Goycoolea, F. M., & Salomon, C. J. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.114743 · Cited by 22 · see citing works

Cell type-targeting nanoparticles in treating central nervous system diseases: Challenges and hopes

Guo, S., & Yi, C. (2023) · Nanotechnology Reviews · doi:10.1515/ntrev-2023-0158 · Cited by 22 · see citing works

Characterization of Gastrointestinal Fate of Nanoemulsions

Zhang, R., & McClements, D. J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811838-2.00018-7 · Cited by 22 · see citing works

Mathematical Modeling and Simulation to Investigate the CNS Transport Characteristics of Nanoemulsion-Based Drug Delivery Following Intranasal Administration

Kadakia, E., Bottino, D. C., & Amiji, M. M. (2019) · Pharmaceutical Research · doi:10.1007/s11095-019-2610-y · Cited by 20 · see citing works

Flavonoids, the Family of Plant-Derived Antioxidants Making Inroads into Novel Therapeutic Design Against Ionizing Radiation-Induced Oxidative Stress in Parkinson’s Disease

Behl, T., Kaur, G., Sehgal, A., Zengin, G., Singh, S., Ahmadi, A., & Bungău, S. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210524152817 · Cited by 13 · see citing works

Nanocarriers for effective drug delivery

Theochari, I., Xenakis, A., & Papadimitriou, V. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816770-0.00019-8 · Cited by 20 · see citing works

Progress and perspectives on nanoplatforms for drug delivery to the brain

Xu, Y., Wei, L., & Wang, H. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.101636 · Cited by 20 · see citing works

Nanotechnology-driven therapies for neurodegenerative diseases: a comprehensive review

Espinosa, J. L., Park, P., Holcomb, M., Godin, B., & Villapol, S. (2024) · Therapeutic Delivery · doi:10.1080/20415990.2024.2401307 · Cited by 19 · see citing works

Biohybrid nanointerfaces for neuromodulation

Filippi, M., Balciunaite, A., & Katzschmann, R. K. (2023) · Nano Today · doi:10.1016/j.nantod.2023.102094 · Cited by 19 · see citing works

Brain-Targeted Polymers for Gene Delivery in the Treatment of Brain Diseases

Lü, Y., & Jiang, C. (2017) · Topics in Current Chemistry · doi:10.1007/s41061-017-0138-3 · Cited by 19 · see citing works

Emerging paradigms in treating cerebral infarction with nanotheranostics: opportunities and clinical challenges

Almalki, W. H., Alghamdi, S. A., Alzahrani, A., & Zhang, W. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.12.018 · Cited by 17 · see citing works

Nanoemulsions for drug delivery

Atanase, L. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91864-0.00009-7 · Cited by 17 · see citing works

Ionizable nanoemulsions for RNA delivery into the central nervous system – importance of diffusivity

Borrajo, M. L., Quijano, A., Lapuhs, P., Rodriguez-Perez, A. I., Anthiya, S., Labandeira-García, J. L., Valenzuela, R., & Alonso, M. J. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.06.051 · Cited by 17 · see citing works

Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis

Panghal, A., & Flora, S. J. S. (2024) · Discover Nano · doi:10.1186/s11671-024-04135-0 · Cited by 19 · see citing works

GastroPlus- and HSPiP-Oriented Predictive Parameters as the Basis of Valproic Acid-Loaded Mucoadhesive Cationic Nanoemulsion Gel for Improved Nose-to-Brain Delivery to Control Convulsion in Humans

Hussain, A., Altamimi, M. A., Mirza, M. A., Ramzan, M., & Khuroo, T. (2023) · Gels · doi:10.3390/gels9080603 · Cited by 16 · see citing works

Therapeutic Approaches for the Delivery ofTNF-αsiRNA

Pandi, P., Jain, A., Saka, R., & Khan, W. (2017) · Therapeutic Delivery · doi:10.4155/tde-2017-0011 · Cited by 16 · see citing works

Emerging Perspectives on Prime Editor Delivery to the Brain

BenDavid, E., Ramezanian, S., Lu, Y., Rousseau, J., Schroeder, A., Lavertu, M., & Tremblay, J. P. (2024) · Pharmaceuticals · doi:10.3390/ph17060763 · Cited by 15 · see citing works

Brain-targeted intranasal delivery of biologics: a perspective for Alzheimer's disease treatment

Li, H., Shen, X., Zhang, B., Li, Y., Alexander, C., Harvey, P., & Zhu, Z. (2025) · RSC Pharmaceutics · doi:10.1039/d5pm00148j · Cited by 15 · see citing works

Advances in Nanomedicines: A Promising Therapeutic Strategy for Ischemic Cerebral Stroke Treatment

Li, J., Xie, F., & Ma, X. (2024) · Nanomedicine · doi:10.2217/nnm-2023-0266 · Cited by 14 · see citing works

Revolutionizing Stroke Care: Nanotechnology-Based Brain Delivery as a Novel Paradigm for Treatment and Diagnosis

Balaji, P. G., Bhimrao, L. S., & Yadav, A. K. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04215-3 · Cited by 17 · see citing works

A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles

Maaz, A., Blagbrough, I. S., & Bank, P. D. (2024) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00639 · Cited by 13 · see citing works

A comprehensive review on carrier mediated nose to brain targeting: emphasis on molecular targets, current trends, future prospects, and challenges

Tomar, S., Yadav, R. K., Shah, K., & Dewangan, H. K. (2022) · International Journal of Polymeric Materials · doi:10.1080/00914037.2022.2124255 · Cited by 12 · see citing works

Biomaterial-based osteoimmunomodulatory strategies via the TLR4-NF-κB signaling pathway: A review

Xing, H., Li, R., Qing, Y., Ying, B., & Qin, Y. (2021) · Applied Materials Today · doi:10.1016/j.apmt.2021.100969 · Cited by 12 · see citing works

Intranasal delivery of iron chelators and management of central nervous system disease

Cheng, R., & Kim, J. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1709259 · Cited by 11 · see citing works

Nose-to-brain delivery of biologics and stem cells

Agrawal, M., Konwar, A. N., Alexander, A., & Borse, V. B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822522-6.00015-1 · Cited by 9 · see citing works

Research advances of in vivo biological fate of food bioactives delivered by colloidal systems

Zhao, C., Liu, D., Feng, L., Cui, J., Du, H., Wang, Y., Xiao, H., & Zheng, J. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2154741 · Cited by 9 · see citing works

Development of nanomedicines for the treatment of Alzheimer’s disease: Raison d’être, strategies, challenges and regulatory aspects

Mazahir, F., Alam, M. I., & Yadav, A. K. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102318 · Cited by 9 · see citing works

Tailor-made nanocargoes as promising tool for brain targeting: Modulated approaches with better therapeutic outcomes

Kumar, V., & Gupta, U. D. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104466 · Cited by 8 · see citing works

Cholesterol-Conjugated siRNA Silencing Tnf for the Treatment of Liver Macrophage-Mediated Acute Inflammation in Nonalcoholic Fatty Liver Disease

Craig, K. P., Abrams, M. T., & Amiji, M. M. (2022) · Nucleic Acid Therapeutics · doi:10.1089/nat.2022.0038 · Cited by 6 · see citing works

Intranasal delivery systems for traumatic brain injury: Advancements and perspectives

Yoo, S. H., Heo, S. C., Bae, J. S., Lee, J. H., Knowles, J. C., & Kim, H. (2025) · Journal of Tissue Engineering · doi:10.1177/20417314251372373 · Cited by 5 · see citing works

Nanoparticle-based strategies for overcoming the blood-brain barrier in CNS disorders and brain cancer: precision diagnostics and therapeutics for Alzheimer’s, Parkinson’s, multiple sclerosis, and glioblastoma

Feyzbakhsh, H. (2025) · Tissue Barriers · doi:10.1080/21688370.2025.2599564 · Cited by 5 · see citing works

Drug delivery systems for neural tissue engineering

Güler, E., Polat, E. B., & Çam, M. E. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90554-1.00012-4 · Cited by 4 · see citing works

Recent Advances in Nose-to-Brain Gene Delivery for Central Nervous System Disorders

Fachel, F. N. S., Salatino‐Oliveira, A., Carniel, W. D. S., Zimmermann, R., Matte, Ú. D. S., Teixeira, H. F., Baldo, G., & Schuh, R. S. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17091177 · Cited by 4 · see citing works

Strategies for enhanced direct nose-to-brain drug delivery

Madav, Y., & Wairkar, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822522-6.00014-x · Cited by 4 · see citing works

Molecular dynamics simulation of siRNA loading into a nanoemulsion as a potential carrier

Pirhadi, S., & Amani, A. (2020) · Journal of Molecular Modeling · doi:10.1007/s00894-020-04471-9 · Cited by 4 · see citing works

Protective effect of nanoemulsions containing CdTe quantum dots with potential application as a diagnostic agent

Gusmão, L. A., Köster, R. W., & Tedesco, A. C. (2024) · Microchimica Acta · doi:10.1007/s00604-024-06690-w · Cited by 3 · see citing works

Microorganisms and cationic surfactants

Kula, N., Mazurkiewicz, E., & Obłąk, E. (2020) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.5604/01.3001.0014.5776 · Cited by 3 · see citing works

Genetic background and diagnosis of Fanconi anemia

Repczyńska, A., & Haus, O. (2020) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.5604/01.3001.0014.6332 · Cited by 3 · see citing works

Applications of direct nose-to-brain drug delivery in biomedicine, biotechnology, tissue engineering, and immunology

Patil, S. B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822522-6.00012-6 · Cited by 3 · see citing works

Nucleus targeting-functionalized cell-membrane nanovesicles for intranasal delivery of therapeutic plasmid DNA into the brain for the treatment of glioblastoma

Park, J. Y., Son, M., Zhuang, C., Choi, U., Park, K., Ahn, S. B., Kang, M., Oh, J., Lee, C., Choi, J. S., et al. (2025) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2025.07.034 · Cited by 3 · see citing works

Nanotherapeutic strategies for mitigating sepsis-induced multiorgan dysfunctions

Kumari, A., Kumar, S., & Shukla, R. (2026) · Nanomedicine · doi:10.1080/17435889.2026.2659343 · Cited by 2 · see citing works

Bone-Marrow-Targeted Nanocomposite Abrogates C-Myb-Survivin Cross Talk in MLL-AF9-Rearranged Acute Myeloid Leukemia in In Vitro and In Vivo Patient-Derived Xenograft Models

Kushwaha, A. C., Boddu, M., Malhotra, P., Karmakar, S., & Choudhury, S. R. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c18737 · Cited by 2 · see citing works

Nanobiotechnologies for stroke treatment

Wan, G., Gu, L., Chen, Y., Wang, Y., Sun, Y., Li, Z., Ma, W., Bao, X., & Wang, R. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2501514 · Cited by 2 · see citing works

On Overcoming Barriers to Application of Neuroinflammation Research

Tobinick, E., Ignatowski, T., & Spengler, R. (2017) · InTech eBooks · doi:10.5772/intechopen.68940 · Cited by 3 · see citing works

Particulate carriers for nose-to-brain delivery

Bahadur, S., & Pathak, K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822522-6.00009-6 · Cited by 2 · see citing works

Current advancements in nasopulmonary drug delivery systems

Ibrahim, A., Aziz, O. A. A., Dena, A. S. A., & El-sherbiny, I. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91668-4.00027-7 · Cited by 2 · see citing works

Bridging the nano-Frontier: revolutionizing lung cancer diagnosis and therapy with nanoparticles

Joseph, J. R., Pavithra, S., Selvakumar, K., & Venkatesh, D. P. (2024) · International Journal of Polymeric Materials · doi:10.1080/00914037.2024.2355182 · Cited by 2 · see citing works

CNS Delivery and Anti-Inflammatory Effects of Intranasally Administered Cyclosporine-A in Cationic Nanoformulations

Yadav, S. K., Pawar, G. N., Kulkarni, P. P., Ferris, C. F., & Amiji, M. M. (2018) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.118.254672 · Cited by 23 · see citing works

Intranasal delivery of cyclosporine to the brain using lipid-based nanocarriers for the treatment of neuro-inflammation

(n.d.) · Digital Repository Service (Northeastern University)

Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain

Kim, I., Shin, J., Kim, S.-W., Choi, S., Ahn, J., Han, P., Park, J. S., & Lee, J.-K. (2012) · Molecular Therapy · doi:10.1038/mt.2011.291 · Cited by 150 · see citing works

Intranasal Tat-modified PEG-PCL nanomicelles delivering anti-RelA siRNA attenuate ischemia-reperfusion injury

Fukuda, M., Oguma, T., Nagatomo, T., Yamaguchi, T., Kosuge, Y., Suzuki, T., & Kanazawa, T. (2026) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2026.103028

Therapeutic Effects in a Transient Middle Cerebral Artery Occlusion Rat Model by Nose-To-Brain Delivery of Anti-TNF-Alpha siRNA with Cell-Penetrating Peptide-Modified Polymer Micelles

Kanazawa, T., Kurano, T., Ibaraki, H., Takashima, Y., Suzuki, T., & Seta, Y. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11090478 · Cited by 55 · see citing works