The DOI matches its Crossref record; 68 of the 70 references it cites were found in a registry or an index.
Designing materials for biology and medicine
Abstract
Biomaterials have played an enormous role in the success of medical devices and drug delivery systems. We discuss here new challenges and directions in biomaterials research. These include synthetic replacements for biological tissues, designing materials for specific medical applications, and materials for new applications such as diagnostics and array technologies.
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In the citing paper
“Fillers such as indocyanine green and Epolight 4121, gold particles [423,424], conductive ceramics, carbon blacks, nanotubes, and even ink [425] may be incorporated in SMPs to improve the heating efficiency [149,311,416,426,427].”
From A review of stimuli-responsive shape memory polymer composites (2013) · cites this paper as [149]
In the citing paper
“Protein-based hydrogels can be outfitted with a broad range of chemical functionalities by introducing noncanonical amino acids208,209; they can also be readily tailored to a wide variety of biomedical contexts210,211 and made thermally responsive212,213.”
From Towards organoid culture without Matrigel (2021) · cites this paper as [210]
Citations
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Tissue microarrays for high-throughput molecular profiling of tumor specimens
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Self-citationPrinting Proteins as Microarrays for High-Throughput Function Determination
MacBeath, G., & Schreiber, S. L. (2000) · Science · doi:10.1126/science.289.5485.1760 · Cited by 2,767
Light-Directed, Spatially Addressable Parallel Chemical Synthesis
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Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications
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Self-citationBell, E., Ivarsson, B., & Merrill, C. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.3.1274 · Cited by 2,069
Cited by
Sorted by citations
Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Altman, G. H., Diaz, F., Jakuba, C., Calabro, T., Horan, R. L., Chen, J., Lu, H., Richmond, J., & Kaplan, D. L. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00353-8 · Cited by 3,458
Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
Boisselier, É., & Astruc, D. (2009) · Chemical Society Reviews · doi:10.1039/b806051g · Cited by 2,832
Synthetic Molecular Motors and Mechanical Machines
Kay, E. R., Leigh, D. A., & Zerbetto, F. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200504313 · Cited by 2,639
Hydrogels with tunable stress relaxation regulate stem cell fate and activity
Chaudhuri, O., Gu, L., Klumpers, D., Darnell, M., Bencherif, S. A., Weaver, J. C., Huebsch, N., Lee, H.-P., Lippens, E., Duda, G. N., et al. (2016) · Nature Materials · doi:10.1038/nmat4489 · Cited by 2,443
Metadata
- Authors
- Langer, R., & Tirrell, D. A.
- Affiliations
- California Institute of Technology (US)
- ORCID
- Tirrell, David A.
- Venue
- Nature
- Published
- 2004-04-01
- Volume
- 428
- Issue
- 6982
- Pages
- 487-492
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2154157809
- Cited by
- 3,198
- References
- 70
- Citations by year
- 2026: 72 · 2025: 83 · 2024: 69 · 2023: 78 · 2022: 98 · 2021: 124 · 2020: 107 · 2019: 139 · 2018: 193 · 2017: 194 · 2016: 219 · 2015: 194 · 2014: 212 · 2013: 196 · 2012: 197
- FWCI
- 21.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Keywords
- biomaterials, tissue engineering, medical devices, drug delivery systems, medical diagnostics, microarray
- MeSH terms
- Animals, Biocompatible Materials, Humans, Medicine, Tissue Engineering, Protein Array Analysis
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