Cited by 1,742Birth, Development, and HealthAnimal Behavior and ReproductionEvolutionary Psychology and Human Behavior

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Developmental plasticity and human health

Open access

Bateson, Patrick, Barker, David, Clutton-Brock, Timothy, Deb, Debal, D'Udine, Bruno, Foley, Robert A., Gluckman, Peter, Godfrey, Keith, Kirkwood, Tom, Lahr, Marta Mirazón, McNamara, John, Metcalfe, Neil B., Monaghan, Patricia, Spencer, Hamish G., Sultan, Sonia E.·2004·Nature

DOI 10.1038/nature02725

Open this paper in CoChat — free account

Abstract

Many plants and animals are capable of developing in a variety of ways, forming characteristics that are well adapted to the environments in which they are likely to live. In adverse circumstances, for example, small size and slow metabolism can facilitate survival, whereas larger size and more rapid metabolism have advantages for reproductive success when resources are more abundant. Often these characteristics are induced in early life or are even set by cues to which their parents or grandparents were exposed. Individuals developmentally adapted to one environment may, however, be at risk when exposed to another when they are older. The biological evidence may be relevant to the understanding of human development and susceptibility to disease. As the nutritional state of many human mothers has improved around the world, the characteristics of their offspring--such as body size and metabolism--have also changed. Responsiveness to their mothers' condition before birth may generally prepare individuals so that they are best suited to the environment forecast by cues available in early life. Paradoxically, however, rapid improvements in nutrition and other environmental conditions may have damaging effects on the health of those people whose parents and grandparents lived in impoverished conditions. A fuller understanding of patterns of human plasticity in response to early nutrition and other environmental factors will have implications for the administration of public health.

Integrity signals

Registry

Crossref · 10.1038/nature02725

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Developmental Plasticity and Evolution
West-Eberhard, M. J. (2003) · doi:10.1093/oso/9780195122343.001.0001 · Cited by 6,115
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?
Neel, J. V. (1962) · Europe PMC (PubMed Central) · Cited by 3,172
Fetal origins of adult disease: strength of effects and biological basis
Barker, D., Eriksson, J., Forsén, T., & Osmond, C. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.6.1235 · Cited by 2,024
Self-citation
Compensation for a bad start: grow now, pay later?
Metcalfe, N. B., & Monaghan, P. (2001) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(01)02124-3 · Cited by 1,948
Self-citation
Phenotypic Plasticity
Pigliucci, M. (2001) · Johns Hopkins University Press eBooks · doi:10.56021/9780801867880 · Cited by 1,833
Early development and fitness in birds and mammals
Lindström, J., & Lindström, J. (1999) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(99)01639-0 · Cited by 1,706
Maternal Effects As Adaptations
(1998) · doi:10.1093/oso/9780195111637.001.0001 · Cited by 1,653
Glucose tolerance in adults after prenatal exposure to famine
Ravelli, A., van der Meulen, J., Michels, R., Osmond, C., Barker, D., Hales, C., & Bleker, O. (1998) · The Lancet · doi:10.1016/s0140-6736(97)07244-9 · Cited by 1,606
Self-citation
Phenotypic Plasticity: Beyond Nature and Nurture
Pigliucci, M. (2001) · Medical Entomology and Zoology · Cited by 1,225
Catch-up growth in childhood and death from coronary heart disease: longitudinal study
Eriksson, J. G., Forsén, T., Tuomilehto, J. O., Winter, P. D., Osmond, C., & Barker, D. J. P. (1999) · Ambulatory Child Health · doi:10.1136/bmj.318.7181.427 · Cited by 1,144
Self-citation

Flagged first, then by citations

Show all 42 references

Research works printed but not linked: 2

Bateson, P. & Martin, P. Design for a Life: How Behaviour Develops (Cape, London, 1999)
Barker, D. J. P. Mothers, Babies and Health in Later Life (Churchill Livingstone, Edinburgh, 1998)

Sorted by citations

Items 301–400 of 998

Impact of Prenatal Stress on Neuroendocrine Programming
Viltart, O., & Vanbesien-Mailliot, C. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.204 · Cited by 91
Food availability affects adult survival trajectories depending on early developmental conditions
Briga, M., Koetsier, E., Boonekamp, J. J., Jimeno, B., & Verhulst, S. (2017) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2016.2287 · Cited by 86
Meat Science And Muscle Biology Symposium: Developmental programming in cattle: Consequences for growth, efficiency, carcass, muscle, and beef quality characteristics1,2
Robinson, D. L., Cafe, L. M., & Greenwood, P. L. (2012) · Journal of Animal Science · doi:10.2527/jas.2012-5799 · Cited by 85
Physiological and morphological correlates of among-individual variation in standard metabolic rate in the leopard frog Rana pipiens
Steyermark, A. C., Miamen, A. G., Feghahati, H. S., & Lewno, A. W. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01492 · Cited by 85
Achievements and challenges in the biology of environmental effects
Rutter, M. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121258109 · Cited by 87
Embryo responses to stress induced by assisted reproductive technologies
Ramos‐Ibeas, P., Heras, S., Gómez‐Redondo, I., Planells, B., Fernández‐González, R., Pericuesta, E., Laguna‐Barraza, R., Pérez‐Cerezales, S., & Gutiérrez‐Adán, A. (2019) · Molecular Reproduction and Development · doi:10.1002/mrd.23119 · Cited by 85
Developmental Constraints in a Wild Primate
Lea, A. J., Jeanne Altmann, A., Alberts, S. C., & Tung, J. (2015) · The American Naturalist · doi:10.1086/681016 · Cited by 85
Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study
Wang, T., Huang, T., Li, Y., Zheng, Y., Manson, J. E., Hu, F. B., & Qi, L. (2016) · Diabetologia · doi:10.1007/s00125-016-4019-z · Cited by 85
Do environments in infancy moderate the association between stress and inflammation in adulthood? Initial evidence from a birth cohort in the Philippines
McDade, T. W., Hoke, M., Borja, J. B., Adair, L. S., & Kuzawa, C. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.08.010 · Cited by 83
Prenatal Stress Produces Sexually Dimorphic and Regionally Specific Changes in Gene Expression in Hippocampus and Frontal Cortex of Developing Rat Offspring
Mychasiuk, R., Gibb, R., & Kolb, B. (2011) · Developmental Neuroscience · doi:10.1159/000335524 · Cited by 83
Elusive inheritance: Transgenerational effects and epigenetic inheritance in human environmental disease
Martos, S. N., Tang, W., & Wang, Z. (2015) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2015.02.011 · Cited by 84
Fetal programming: Adaptive life-history tactics or making the best of a bad start?
Jones, J. H. (2004) · American Journal of Human Biology · doi:10.1002/ajhb.20099 · Cited by 83
Environmental regulation of the neural epigenome
Caldji, C., Hellstrom, I. C., Zhang, T.-Y., Diorio, J., & Meaney, M. J. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.03.032 · Cited by 82
Sex Differences in Brain Epigenetics
Menger, Y., Bettscheider, M., Murgatroyd, C., & Spengler, D. (2010) · Epigenomics · doi:10.2217/epi.10.60 · Cited by 82
Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome
Kim, J. H., Sartor, M. A., Rozek, L. S., Faulk, C. D., Anderson, O. S., Jones, T. R., Nahar, M. S., & Dolinoy, D. C. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-30 · Cited by 84
Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO)
the S-PRESTO Study Group, Loo, E. X. L., Soh, S., Loy, S. L., Ng, S., Tint, M. T., Chan, S., Huang, J. Y., Yap, F. K. P., Tan, K. H., et al. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00697-2 · Cited by 87
Self-citation
Diet during pregnancy, neonatal outcomes and later health
Moore, V., & Davies, M. J. (2005) · Reproduction Fertility and Development · doi:10.1071/rd04094 · Cited by 82
Modifications of Glucocorticoid Receptors mRNA Expression in the Hypothalamic‐Pituitary‐Adrenal Axis in Response to Early‐life Stress in Female Japanese Quail
Zimmer, C., & Spencer, K. A. (2014) · Journal of Neuroendocrinology · doi:10.1111/jne.12228 · Cited by 78
Increased reproductive success of women after prenatal undernutrition
Painter, R. C., Westendorp, R. G. J., de Rooij, S. R., Osmond, C., Barker, D. J. P., & Roseboom, T. J. (2008) · Human Reproduction · doi:10.1093/humrep/den274 · Cited by 82
Self-citation
Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero
Wong‐Goodrich, S. J. E., Glenn, M. J., Mellott, T. J., Blusztajn, J. K., Meck, W. H., & Williams, C. L. (2008) · Brain Research · doi:10.1016/j.brainres.2008.08.074 · Cited by 81
Alimentary epigenetics: a developmental psychobiological systems view of the perception of hunger, thirst and satiety
HARSHAW, C. (2008) · Developmental Review · doi:10.1016/j.dr.2008.08.001 · Cited by 80
Metabolic and Genomic Response to Dietary Isocaloric Protein Restriction in the Rat
Kalhan, S. C., Uppal, S. O., Moorman, J. L., Bennett, C. D., Gruca, L. L., Parimi, P. S., Dasarathy, S., Serre, D., & Hanson, R. W. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.185991 · Cited by 80
Birthweight and paternal involvement predict early reproduction in British women: Evidence from the National Child Development Study
Nettle, D., Coall, D. A., & Dickins, T. E. (2009) · American Journal of Human Biology · doi:10.1002/ajhb.20970 · Cited by 80
Breath of Life: Heart Disease Link to Developmental Hypoxia
Giussani, D. A. (2021) · Circulation · doi:10.1161/circulationaha.121.054689 · Cited by 82
The Metabolic Ghetto
Wells, J. C. K. (2016) · Cambridge University Press eBooks · doi:10.1017/cbo9780511972959 · Cited by 83
Early Environments, Stress, and the Epigenetics of Human Health
Mulligan, C. J. (2016) · Annual Review of Anthropology · doi:10.1146/annurev-anthro-102215-095954 · Cited by 82
Developmental origins of child mental health disorders
Swanson, J. D., & Wadhwa, P. M. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.02014.x · Cited by 78
Phenotypic plasticity: a useful framework for understanding adaptation in forest species
Chambel, M. R., Climent, J., Alı́a, R., & Valladares, F. (2005) · Forest Systems · doi:10.5424/srf/2005143-00924 · Cited by 78
Early development, recruitment and life history trajectory in long-lived birds
Cam, E., & Aubry, L. M. (2011) · Journal für Ornithologie · doi:10.1007/s10336-011-0707-0 · Cited by 79
Comparative cardiovascular physiology: future trends, opportunities and challenges
Burggren, W. W., Christoffels, V. M., Crossley, D. A., Enok, S., Farrell, A. P., Hedrick, M. S., Hicks, J. W., Jensen, B. K., Moorman, A. F. M., Mueller, C. A., et al. (2013) · Acta Physiologica · doi:10.1111/apha.12170 · Cited by 78
Defining individual quality over lifetimes and selective contexts
Lailvaux, S. P., & Kasumovic, M. M. (2010) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2010.1591 · Cited by 77
Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk
Wang, Q., Treviño, L. S., Wong, R. L. Y., Medvedovic, M., Chen, J., Ho, S., Shen, J., Foulds, C. E., Coarfa, C., O’Malley, B. W., et al. (2016) · Molecular Endocrinology · doi:10.1210/me.2015-1310 · Cited by 77
Behavioral Response of Mothers and Infants to Variation in Maternal Condition: Adaptation, Compensation, and Resilience
Fairbanks, L. A., & Hinde, K. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4060-4_13 · Cited by 77
Perinatal Lead (Pb) Exposure Results in Sex-Specific Effects on Food Intake, Fat, Weight, and Insulin Response across the Murine Life-Course
Faulk, C. D., Barks, A. K., Sánchez, B. N., Zhang, Z., Anderson, O. S., Peterson, K. E., & Dolinoy, D. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104273 · Cited by 77
Folate depletion during pregnancy and lactation reduces genomic DNA methylation in murine adult offspring
McKay, J. A., Waltham, K. J., Williams, E. A., & Mathers, J. C. (2010) · Genes & Nutrition · doi:10.1007/s12263-010-0199-1 · Cited by 79
Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats
Tong, W., Qin, X. Y., Li, Y., & Zhang, L. (2011) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00356.2011 · Cited by 79
Epigenetic programming by early-life stress
Alyamani, R. A. S., & Murgatroyd, C. (2018) · Progress in Molecular Biology and Translational Science · doi:10.1016/bs.pmbts.2018.01.004 · Cited by 76
The Disposable Soma Theory
Kirkwood, T. B. L. (2017) · Cambridge University Press eBooks · doi:10.1017/9781139939867.002 · Cited by 76
Self-citation
A biocultural study of the effects of maternal stress on mother and newborn health in the D emocratic R epublic of C ongo
Rodney, N. C., & Mulligan, C. J. (2014) · American Journal of Physical Anthropology · doi:10.1002/ajpa.22568 · Cited by 79
Understanding and testing risk mechanisms for mental disorders
Rutter, M. L. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01976.x · Cited by 82
Maternal environment and the reproductive function of the offspring
Dupont, C., Cordier, A., Junien, C., Mandon‐Pepin, B., Lévy, R., & Chavatte‐Palmer, P. (2012) · Theriogenology · doi:10.1016/j.theriogenology.2012.06.016 · Cited by 76
Gene–environment interaction during early development in the heterozygous reeler mouse: Clues for modelling of major neurobehavioral syndromes
Laviola, G., Ognibene, E., Romano, E., Adriani, W., & Keller, F. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.09.006 · Cited by 76
Cardiovascular consequences of famine in the young
van Abeelen, A. F. M., Elias, S. G., Bossuyt, P. M., Grobbee, D. E., van der Schouw, Y. T., Roseboom, T. J., & Uiterwaal, C. S. P. M. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr228 · Cited by 76
Evolutionary Psychology and Mental Health
Nesse, R. M. (2015) · Wiley eBooks · doi:10.1002/9780470939376.ch32 · Cited by 76
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes
Chen, L., Pan, H., Tuan, T. A., Teh, A. L., MacIsaac, J. L., Mah, S. M., McEwen, L. M., Li, Y., Chen, H., Broekman, B. F. P., et al. (2015) · Development and Psychopathology · doi:10.1017/s0954579414001357 · Cited by 75
Self-citation
Dairy and plant based food intakes are associated with altered faecal microbiota in 2 to 3 year old Australian children
Smith‐Brown, P., Morrison, M., Krause, L., & Davies, P. S. W. (2016) · Scientific Reports · doi:10.1038/srep32385 · Cited by 99
Genome-wide microRNA expression profiling in placentae from frozen-thawed blastocyst transfer
Hiura, H., Hattori, H., Kobayashi, N., Okae, H., Chiba, H., Miyauchi, N., Kitamura, A., Kikuchi, H., Yoshida, H., & Arima, T. (2017) · Clinical Epigenetics · doi:10.1186/s13148-017-0379-6 · Cited by 75
Long-term health outcomes of children born to mothers with hyperemesis gravidarum: a systematic review and meta-analysis
Nijsten, K., Jansen, L. A. W., Limpens, J., Finken, M. J. J., Koot, M. H., Grooten, I. J., Roseboom, T. J., & Painter, R. C. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.03.052 · Cited by 74
Cell sensitivity, non-linearity and inverse effects
Bellavite, P., Signorini, A. M., Marzotto, M., Moratti, E., Bonafini, C., & Olioso, D. (2015) · Homeopathy · doi:10.1016/j.homp.2015.02.002 · Cited by 73
Living with the Past: Nutritional Stress in Juvenile Males Has Immediate Effects on their Plumage Ornaments and on Adult Attractiveness in Zebra Finches
Naguib, M., & Nemitz, A. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000901 · Cited by 74
Perinatal Nicotine Exposure Increases Vulnerability of Hypoxic–Ischemic Brain Injury in Neonatal Rats
Li, Y., Xiao, D., Dasgupta, C., Xiong, F., Tong, W., Yang, S., & Zhang, L. (2012) · Stroke · doi:10.1161/strokeaha.112.664698 · Cited by 75
Folate and long-chain polyunsaturated fatty acids in psychiatric disease
Muskiet, F. A. J., & Kemperman, R. F. J. (2006) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2006.02.001 · Cited by 74
Is natural experiment a cure? Re-examining the long-term health effects of China's 1959–1961 famine
Xu, H., Li, L., Zhang, Z., & Liu, J. (2015) · Social Science & Medicine · doi:10.1016/j.socscimed.2015.11.028 · Cited by 73
Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids
Hong, J. Y., Lim, J., Carvalho, F., Cho, J. Y., Vaidyanathan, B., Yu, S., Annicelli, C., Ip, W., & Medzhitov, R. M. (2020) · Cell · doi:10.1016/j.cell.2020.02.018 · Cited by 74
Bone histology confirms determinate growth and small body size in the noasaurid theropodMasiakasaurus knopfleri
Lee, A. H., & O’Connor, P. M. (2013) · Journal of Vertebrate Paleontology · doi:10.1080/02724634.2013.743898 · Cited by 73
The evolution and expression of virulence
Ebert, D., & Bull, J. J. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199207466.003.0012 · Cited by 75
Kidney and epigenetic mechanisms of salt-sensitive hypertension
Kawarazaki, W., & Fujita, T. (2021) · Nature Reviews Nephrology · doi:10.1038/s41581-021-00399-2 · Cited by 73
Early environmental factors, alteration of epigenetic marks and metabolic disease susceptibility
Portha, B., Fournier, A., Kioon, M. D. A., Mezger, V., & Movassat, J. (2013) · Biochimie · doi:10.1016/j.biochi.2013.10.003 · Cited by 79
The Influence of Birth Size on Intelligence in Healthy Children
Broekman, B. F. P., Chan, Y., Chong, Y. S., Quek, S., Fung, D. S. S., Low, Y.-L., Ooi, Y. P., Gluckman, P. D., Meaney, M. J., Wong, T. Y., et al. (2009) · PEDIATRICS · doi:10.1542/peds.2008-3344 · Cited by 73
Self-citation
Stress and body condition are associated with climate and demography in Asian elephants
Mumby, H. S., Mar, K. U., Thitaram, C., Courtiol, A., Towiboon, P., Min-Oo, Z., Htut-Aung, Y., Brown, J. L., & Lummaa, V. (2015) · Conservation Physiology · doi:10.1093/conphys/cov030 · Cited by 72
Exploring the folkbiological conception of human nature
Linquist, S., Machery, É., Griffiths, P. E., & Stotz, K. C. (2011) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2010.0224 · Cited by 72
Foetal hypoxia increases cardiac AT2R expression and subsequent vulnerability to adult ischaemic injury
Qin, X. Y., Dasgupta, C., Chen, M., & Zhang, L. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq303 · Cited by 71
Effects of in Utero PFOS Exposure on Transcriptome, Lipidome, and Function of Mouse Testis
Lai, K. P., Lee, J. C., Wan, H. T., Li, J., Wong, A. Y.-M., Chan, T., Oger, C., Galano, J., Durand, T., Leung, K. S., et al. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b02102 · Cited by 72
Population genetics of venous thromboembolism
Grandone, E., & Margaglione, M. (2010) · Thrombosis and Haemostasis · doi:10.1160/th10-08-0510 · Cited by 72
Low Birthweight Is Associated With Narrower Arterioles in Adults
Liew, G., Wang, J. J., Duncan, B. B., Klein, R., Sharrett, A. R., Brancati, F. L., Yeh, H., Mitchell, P., & Wong, T. Y. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.101584 · Cited by 71
Rensch's rule in insects: patterns among and within species
Blanckenhorn, W. U., Meier, R., & Teder, T. (2007) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199208784.003.0007 · Cited by 71
Chapter 6 Information Warfare and Parent–Offspring Conflict
Kilner, R. M., & Hinde, C. A. (2008) · Advances in the study of behavior · doi:10.1016/s0065-3454(08)00006-5 · Cited by 71
Fetal and Neonatal Pathways to Obesity
Gluckman, P. D., Hanson, M. A., Beedle, A. S., & Raubenheimer, D. (2008) · Frontiers of hormone research · doi:10.1159/000115337 · Cited by 71
Self-citation
Maternal smoking in pregnancy is associated with cholesterol development in the offspring: A 27-years follow-up study
Jaddoe, V. W. V., de Ridder, M. A. J., van den Elzen, A. P. M., Albert Hofman, D., Uiterwaal, C. S. P. M., & Witteman, J. C. M. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.01.032 · Cited by 71
Individual Differences in Developmental Plasticity May Result From Stochastic Sampling
Frankenhuis, W. E., & Panchanathan, K. (2011) · Perspectives on Psychological Science · doi:10.1177/1745691611412602 · Cited by 77
Kinase-KCC2 coupling: Cl − rheostasis, disease susceptibility, therapeutic target
Kahle, K. T., & Delpire, E. J. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00865.2015 · Cited by 69
Seal mothers expend more on offspring under favourable conditions and less when resources are limited
McMahon, C. R., Harcourt, R. G., Burton, H. R., Daniel, O., & Hindell, M. A. (2016) · Journal of Animal Ecology · doi:10.1111/1365-2656.12611 · Cited by 71
A case for environmental statistics of early-life effects
Frankenhuis, W. E., Nettle, D., & Dall, S. R. X. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2018.0110 · Cited by 79
Rapid Growth in Infancy
Weaver, L. T. (2006) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000235977.59873.e0 · Cited by 70
Early Nutrition and Long-Term Cardiovascular Health
Singhal, A. (2006) · Nutrition Reviews · doi:10.1301/nr.2006.may.s44-s49 · Cited by 70
Catch‐up growth strategies differ between body structures: interactions between age and structure‐specific growth in wild nestling Alpine Swifts
Bize, P., Metcalfe, N. B., & Roulin, A. (2006) · Functional Ecology · doi:10.1111/j.1365-2435.2006.01157.x · Cited by 70
Self-citation
Uncovering system-specific stress signatures in primate teeth with multimodal imaging
Austin, C. E., Smith, T. M., Farahani, R. H., Hinde, K., Carter, E. A., Lee, J., Lay, P. A., Kennedy, B. J., Sarrafpour, B., Wright, R. J., et al. (2016) · Scientific Reports · doi:10.1038/srep18802 · Cited by 73
Prenatal nutrition and the risk of adult obesity: Long-term effects of nutrition on epigenetic mechanisms regulating gene expression
Navarro, E., Funtikova, A. N., Fitó, M., & Schröder, H. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.03.012 · Cited by 72
Mycotoxin exposure biomonitoring in breastfed and non-exclusively breastfed Nigerian children
Ezekiel, C. N., Abia, W. A., Braun, D., Šarkanj, B., Ayeni, K. I., Oyedele, O. A., Michael-Chikezie, E. C., Ezekiel, V. C., Mark, B. N., Ahuchaogu, C. P., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106996 · Cited by 69
An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome
Ahmed, T., Auble, D., Berkley, J. A., Black, R. E., Ahern, P. P., Hossain, M., Hsieh, A. T., Ireen, S., Arabi, M., & Gordon, J. I. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12487 · Cited by 71
Prenatal stress produces anxiety prone female offspring and impaired maternal behaviour in the domestic pig
Rutherford, K., Piastowska‐Ciesielska, A. W., Donald, R. D., Robson, S. K., Ison, S. H., Jarvis, S., Brunton, P. J., Russell, J. A., & Lawrence, A. B. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.02.052 · Cited by 69
Transgenerational effects of impaired maternal care on behaviour of offspring and grandoffspring
Curley, J. P., Champagne, F. A., Bateson, P., & Keverne, E. B. (2008) · Animal Behaviour · doi:10.1016/j.anbehav.2007.10.008 · Cited by 69
Self-citation
The Polycystic Ovary Syndrome and recent human evolution
Corbett, S., & Morin-Papunen, L. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.01.001 · Cited by 68
Maternal periconceptual nutrition, early pregnancy, and developmental outcomes in beef cattle
Caton, J. S. S., Crouse, M. S., McLean, K. J., Dahlen, C. R., Ward, A. K. K., Cushman, R. A., Grazul‐Bilska, A. T., Neville, B. W., Borowicz, P. P. P., & Reynolds, L. P. (2020) · Journal of Animal Science · doi:10.1093/jas/skaa358 · Cited by 68
Stressful Dieting: Nutritional Conditions but Not Compensatory Growth Elevate Corticosterone Levels in Zebra Finch Nestlings and Fledglings
Honarmand, M., Goymann, W., & Naguib, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012930 · Cited by 68
A critical appraisal of the predictive adaptive response hypothesis
Wells, J. C. K. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dyr239 · Cited by 69
Early Nutrition: Impact on Epigenetics
Mathers, J. C. (2007) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000107066 · Cited by 67
Norepinephrine causes epigenetic repression of PKCε gene in rodent hearts by activating Nox1‐dependent reactive oxygen species production
Xiong, F., Xiao, D., & Zhang, L. (2012) · The FASEB Journal · doi:10.1096/fj.11-199422 · Cited by 71
In-utero and perinatal influences on suicide risk: a systematic review and meta-analysis
Orri, M., Gunnell, D., Richard‐Devantoy, S., Bolanis, D., Boruff, J. T., Turecki, G., & Geoffroy, M. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30077-x · Cited by 72
Then versus now: effect of developmental and current environmental conditions on incubation effort in birds
Spencer, K. A., Heidinger, B. J., D’Alba, L., Evans, N. P., & Monaghan, P. (2010) · Behavioral Ecology · doi:10.1093/beheco/arq090 · Cited by 66
Self-citation
ART and health: clinical outcomes and insights on molecular mechanisms from rodent studies
Feuer, S. K., Camarano, L., & Rinaudo, P. F. (2012) · Molecular Human Reproduction · doi:10.1093/molehr/gas066 · Cited by 69
Developmental Plasticity
Taborsky, B. (2017) · Advances in the study of behavior · doi:10.1016/bs.asb.2016.12.002 · Cited by 70
Transgenerational effects of parental light environment on progeny competitive performance and lifetime fitness
Baker, B. H., Sultan, S. E., Lopez-Ichikawa, M. A., & Waterman, R. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2018.0182 · Cited by 66
Self-citation
Association Between Ambient Air Pollution and Birth Weight by Maternal Individual- and Neighborhood-Level Stressors
Niu, Z., Habre, R., Chavez, T., Yang, T., Grubbs, B. H., Eckel, S. P., Berhane, K. T., Toledo‐Corral, C. M., Johnston, J., Dunton, G. F., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.38174 · Cited by 67
Long-term effects of birth weight and breastfeeding duration on inflammation in early adulthood
McDade, T. W., Metzger, M. W., Chyu, L., Duncan, G. J., Garfield, C. F., & Adam, E. K. (2014) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2013.3116 · Cited by 67
Early life conditions, reproductive and sexuality-related life history outcomes among human males: A systematic review and meta-analysis
Xu, Y., Norton, S., & Rahman, Q. (2017) · Evolution and Human Behavior · doi:10.1016/j.evolhumbehav.2017.08.005 · Cited by 72
Type 2 diabetes, cardiovascular disease, and the evolutionary paradox of the polycystic ovary syndrome: A fertility first hypothesis
Corbett, S. J., McMichael, A. J., & Prentice, A. M. (2009) · American Journal of Human Biology · doi:10.1002/ajhb.20937 · Cited by 64
Mapping complex traits as a dynamic system
Sun, L., & Wu, R. (2015) · Physics of Life Reviews · doi:10.1016/j.plrev.2015.02.007 · Cited by 66
Resilience and vulnerability are dose-dependently related to neonatal stressors in mice
Macrı̀, S., Granstrem, O., Shumilina, M. V., Santos, F. J., Berry, A., Saso, L., & Laviola, G. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.07.006 · Cited by 68
The next generation of disease risk: Are the effects of prenatal nutrition transmitted across generations? Evidence from animal and human studies
Roseboom, T. J., & Watson, E. D. (2012) · Placenta · doi:10.1016/j.placenta.2012.07.018 · Cited by 64

Authors: Bateson, P., Barker, D., Clutton-Brock, T., Deb, D., D'Udine, B., Foley, R. A., Gluckman, P., Godfrey, K., Kirkwood, T., Lahr, M. M., McNamara, J., Metcalfe, N. B., Monaghan, P., Spencer, H. G., & Sultan, S. E.
Affiliations: University of Cambridge (GB)
Southampton General Hospital (GB)
Center for Interdisciplinary Studies (IN)
University of Auckland (NZ)
University of Bristol (GB)
University of Glasgow (GB)
University of Otago (NZ)
Wesleyan University (US)
Corresponding author: Bateson, Patrick
ORCID: Bateson, Patrick
Deb, Debal
Foley, Robert A.
Gluckman, Peter
Godfrey, Keith
McNamara, John
Metcalfe, Neil B.
Spencer, Hamish G.
Sultan, Sonia E.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2004-07
Volume: 430
Issue: 6998
Pages: 419-421
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/nature02725
OpenAlex: W2049590417
Cited by: 1,742
References: 42
Citations by year: 2026: 28 · 2025: 47 · 2024: 44 · 2023: 46 · 2022: 85 · 2021: 72 · 2020: 60 · 2019: 66 · 2018: 84 · 2017: 81 · 2016: 99 · 2015: 87 · 2014: 106 · 2013: 102 · 2012: 129
FWCI: 70.25
Type: journal article
Language: en
Open access: green
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
Wesleyan University Digital Collections (Wesleyan University) (submittedVersion)
RePEc: Research Papers in Economics (submittedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
ePrints Soton (University of Southampton) (submittedVersion)
Bristol Research (University of Bristol) (submittedVersion)
Explore Bristol Research (submittedVersion)
Newcastle University ePrints (Newcastle Univesity)
Funders: Biotechnology and Biological Sciences Research Council (BEP17 042)
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
Social Sciences › Psychology › Experimental and Cognitive Psychology › Evolutionary Psychology and Human Behavior
Keywords: developmental plasticity, human health, early life environment, maternal nutrition, fetal programming, body size, metabolism, disease susceptibility, environmental mismatch, public health policy, epigenetic inheritance
MeSH terms: Adaptation, Physiological, Animals, Body Constitution, Cues, Disease Susceptibility, Energy Metabolism, Female, Embryonic and Fetal Development, Health, Humans, Infant, Newborn, Male, Nutritional Physiological Phenomena, Pregnancy, Public Health

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Developmental plasticity and human health

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks