Autophagy fights disease through cellular self-digestion

Autophagy in the Pathogenesis of Disease

Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J.-A., Outzen, H., Øvervatn, A., Bjørkøy, G., & Johansen, T. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702824200 · Cited by 4,578

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., Yokoyama, M., Mishima, K., Saito, I., Okano, H., et al. (2006) · Nature · doi:10.1038/nature04724 · Cited by 3,882

Self-eating and self-killing: crosstalk between autophagy and apoptosis

Maiuri, M. C., Zalckvar, E., Kimchi, A., & Kroemer, G. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2239 · Cited by 3,638

Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

Pattingre, S., Tassa, A., Qu, X., Garuti, R., Liang, X. H., Mizushima, N., Packer, M., Schneider, M. D., & Levine, B. (2005) · Cell · doi:10.1016/j.cell.2005.07.002 · Cited by 3,536

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J.-I., Tanida, I., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., et al. (2006) · Nature · doi:10.1038/nature04723 · Cited by 3,500

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200507002 · Cited by 3,276

The role of autophagy during the early neonatal starvation period

Kuma, A., Hatano, M., Matsui, M., Yamamoto, A., Nakaya, H., Yoshimori, T., Ohsumi, Y., Tokuhisa, T., & Mizushima, N. (2004) · Nature · doi:10.1038/nature03029 · Cited by 2,865

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1362 · Cited by 2,347

Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization

Yang, M. H., Liu, J., Shao, J., Qin, Y., Ji, Q., Zhang, X., & Du, J. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-43 · Cited by 139

Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra‐Muscle Fiber Multi‐Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation

Askanas, V., Engel, W. K., & Nogalska, A. (2009) · Brain Pathology · doi:10.1111/j.1750-3639.2009.00290.x · Cited by 139

Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Cheng, H.-C., Kim, S. R., Oo, T. F., Kareva, T., Yarygina, O., Rzhetskaya, M., Wang, C., During, M. J., Tallóczy, Z., Tanaka, K., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5519-10.2011 · Cited by 138

Roles of the Lipid-binding Motifs of Atg18 and Atg21 in the Cytoplasm to Vacuole Targeting Pathway and Autophagy

Nair, U., Cao, Y., Xie, Z., & Klionsky, D. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.080374 · Cited by 138

Crucial role for autophagy in degranulation of mast cells

Ushio, H., Ueno, T., Kojima, Y., Komatsu, M., Tanaka, S., Yamamoto, A., Ichimura, Y., Ezaki, J., Nishida, K., Komazawa-Sakon, S., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.12.1078 · Cited by 124

Zearalenone induces apoptosis and cytoprotective autophagy in primary Leydig cells

Wang, Y., Zheng, W., Bian, X., Yuan, Y., Gu, J., Liu, X., Liu, Z., & Bian, J. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.02.003 · Cited by 138

Research progress of hydroxychloroquine and autophagy inhibitors on cancer

Shi, T., Yu, X., Li-jun, Y., & Xiao, H. (2016) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-016-3197-1 · Cited by 138

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection

Lee, W.-S., Webster, J. A., Madzokere, E. T., Skinner, E. B., & Herrero, L. J. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3433-8 · Cited by 139

Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection

Caramés, B., Taniguchi, N., Seino, D., Blanco, F. J., DʼLima, D. D., & Lotz, M. (2011) · Arthritis & Rheumatism · doi:10.1002/art.33444 · Cited by 138

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage

Dewaele, M., Martinet, W., Rubio, N., Verfaillie, T., de Witte, P. A. M., Piette, J. G., & Agostinis, P. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01118.x · Cited by 139

XIAP inhibits autophagy via XIAP‐Mdm2‐p53 signalling

Huang, X., Wu, Z., Mei, Y., & Wu, M. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.133 · Cited by 138

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Eisenberg‐Lerner, A., & Kimchi, A. (2011) · Cell Death and Differentiation · doi:10.1038/cdd.2011.149 · Cited by 137

Models of α-synuclein aggregation in Parkinson’s disease

Giráldez‐Pérez, R. M., Antolín‐Vallespín, M., Muñoz, M.-D., & Sánchez‐Capelo, A. (2014) · Acta Neuropathologica Communications · doi:10.1186/s40478-014-0176-9 · Cited by 140

TXNIP/Redd1 signalling and excessive autophagy: a novel mechanism of myocardial ischaemia/reperfusion injury in mice

Gao, C., Wang, R., Li, B., Guo, Y., Yin, T., Xia, Y., Zhang, F., Lian, K., Liu, Y., Wang, H., et al. (2019) · Cardiovascular Research · doi:10.1093/cvr/cvz152 · Cited by 137

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis

Takahashi, A., Kimura, F., Yamanaka, A., Takebayashi, A., Kita, N., Takahashi, K., & Murakami, T. (2014) · Cancer Cell International · doi:10.1186/1475-2867-14-53 · Cited by 136

Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex

McKnight, N. C., Zhong, Y., Wold, M. S., Gong, S., Phillips, G. R., Dou, Z., Zhao, Y., Heintz, N., Zong, W.-X., & Yue, Z. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004626 · Cited by 136

The regulatory roles of p53 in cardiovascular health and disease

Men, H., Cai, H., Cheng, Q., Zhou, W., Wang, X., Huang, S., Zheng, Y., & Cai, L. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03694-6 · Cited by 137

Pompe Disease

Dasouki, M., Jawdat, O., Almadhoun, O. F., Pasnoor, M., McVey, A., Abuzinadah, A. R., Herbelin, L. L., Barohn, R. J., & Dimachkie, M. M. (2014) · Neurologic Clinics · doi:10.1016/j.ncl.2014.04.010 · Cited by 136

MIR34Aregulates autophagy and apoptosis by targetingHMGB1in the retinoblastoma cell

Liu, K., Huang, J. X., Xie, M., Yu, Y. H., Zhu, S., Kang, R., Cao, L., Tang, D., & Duan, X. (2014) · Autophagy · doi:10.4161/auto.27418 · Cited by 137

Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

Keil, E., Höcker, R., Schuster, M., Eßmann, F., Ueffing, N., Hoffman‐Liebermann, B., Liebermann, D. A., Pfeffer, K., Schulze‐Osthoff, K., & Schmitz, I. (2012) · Cell Death and Differentiation · doi:10.1038/cdd.2012.129 · Cited by 135

A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy

Jao, C. C., Ragusa, M. J., Stanley, R. E., & Hurley, J. H. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1220306110 · Cited by 135

COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs

Gurpinar, E., Grizzle, W. E., & Piazza, G. A. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00181 · Cited by 135

Cadmium-Based Quantum Dot Induced Autophagy Formation for Cell Survival via Oxidative Stress

Luo, Y.-H., Wu, S., Wei, Y., Chen, Y.-C., Tsai, M., Ho, C.-C., Lin, S., Yang, C., & Lin, P. (2013) · Chemical Research in Toxicology · doi:10.1021/tx300455k · Cited by 135

Reticulophagy and Ribophagy: Regulated Degradation of Protein Production Factories

Cebollero, E., Reggiori, F., & Kraft, C. (2012) · International Journal of Cell Biology · doi:10.1155/2012/182834 · Cited by 135

Rab11 facilitates cross-talk between autophagy and endosomal pathway through regulation of Hook localization

Szatmári, Z., Kis, V., Lippai, M., Hegedűs, K., Faragó, T., Lőrincz, P., Tanaka, T., Juhász, G., & Sass, M. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-10-0574 · Cited by 135

FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice

Liu, T., Xiong, X., Ren, X., Zhao, M., Shi, C., Wang, J., Zhou, Y., Zhang, F., Han, Y., Gao, X.-Y., et al. (2016) · Diabetes · doi:10.2337/db16-0356 · Cited by 135

Dengue Virus Activates the AMP Kinase-mTOR Axis To Stimulate a Proviral Lipophagy

Jordan, T. X., & Randall, G. C. (2017) · Journal of Virology · doi:10.1128/jvi.02020-16 · Cited by 135

Glutamine Addiction and Therapeutic Strategies in Lung Cancer

Vanhove, K., Derveaux, E., Graulus, G., Mesotten, L., Thomeer, M., Noben, J., Guedens, W., & Adriaensens, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20020252 · Cited by 135

EPA, an omega‐3 fatty acid, induces apoptosis in human pancreatic cancer cells: Role of ROS accumulation, caspase‐8 activation, and autophagy induction

Fukui, M., Kang, K. S., Okada, K., & Zhu, B. T. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24354 · Cited by 134

Class IA PI3K p110β Subunit Promotes Autophagy through Rab5 Small GTPase in Response to Growth Factor Limitation

Dou, Z., Pan, J.-A., Dbouk, H. A., Ballou, L. M., DeLeon, J. L., Fan, Y., Chen, J.-S., Liang, Z., Li, G., Backer, J., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.022 · Cited by 134

The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis

Lenna, S., & Trojanowska, M. (2012) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e3283588dbb · Cited by 134

Yersinia pestisCan Reside in Autophagosomes and Avoid Xenophagy in Murine Macrophages by Preventing Vacuole Acidification

Pujol, C., Klein, K. A., Romanov, G. A., Palmer, L. E., Cirota, C., Zhao, Z., & Bliska, J. B. (2009) · Infection and Immunity · doi:10.1128/iai.00068-09 · Cited by 134

Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging

Horan, M. P., Pichaud, N., & Ballard, J. W. O. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr263 · Cited by 136

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

Zhang, N., Chen, Y., Jiang, R., Li, E., Chen, X., Xi, Z., Guo, Y., Liu, X., Zhou, Y., Che, Y., et al. (2011) · Autophagy · doi:10.4161/auto.7.6.15103 · Cited by 134

Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers

Poluzzi, C., Iozzo, R. V., & Schaefer, L. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.10.012 · Cited by 134

Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease

Son, S. M., Cha, M.-Y., Choi, H., Kang, S., Choi, H., Lee, M., Park, S. A., & Mook‐Jung, I. (2016) · Autophagy · doi:10.1080/15548627.2016.1159375 · Cited by 134

Curcumin Inhibits Apoptosis of Chondrocytes through Activation ERK1/2 Signaling Pathways Induced Autophagy

Li, X., Feng, K., Li, J., Yu, D., Fan, Q., Tang, T., Yao, X., & Wang, X. (2017) · Nutrients · doi:10.3390/nu9040414 · Cited by 134

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency

Luciani, A., Schumann, A., Berquez, M., Chen, Z., Nieri, D., Failli, M., Debaix, H., Festa, B. P., Tokonami, N., Raimondi, A., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-14729-8 · Cited by 134

Neutrophils as effector cells for antibody-based immunotherapy of cancer

van Egmond, M., & Bakema, J. E. (2012) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2012.12.002 · Cited by 134

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

Silva, D. F., Selfridge, J. E., Lu, J., E, L., Roy, N., Hutfles, L., Burns, J. M., Michaelis, E. K., Yan, S., Cardoso, S. M., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt247 · Cited by 133

Deregulation of cell signaling in cancer

Giancotti, F. G. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.02.005 · Cited by 133

Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy

Huang, H., Kang, R., Wang, J., Luo, G. G., Yang, W. Z., & Zhao, Z. (2012) · Autophagy · doi:10.4161/auto.22791 · Cited by 133

Kinetics and protective role of autophagy in a mouse cecal ligation and puncture-induced sepsis

Takahashi, W., Watanabe, E., Fujimura, L., Watanabe‐Takano, H., Yoshidome, H., Swanson, P. E., Tokuhisa, T., Oda, S., & Hatano, M. (2013) · Critical Care · doi:10.1186/cc12839 · Cited by 133

The TRIMendous Role of TRIMs in Virus–Host Interactions

van Tol, S., Hage, A., Giraldo, M. I., Bharaj, P., & Rajsbaum, R. (2017) · Vaccines · doi:10.3390/vaccines5030023 · Cited by 133

METTL14 facilitates global genome repair and suppresses skin tumorigenesis

Yang, Z., Yang, S., Cui, Y., Wei, J., Shah, P., Park, G., Cui, X., He, C., & He, Y. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2025948118 · Cited by 133

Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application

Gao, H., Yin, J., Ji, C., Yu, X., Xue, J., Guan, X., Zhang, S., Liu, X., & Xing, F. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02805-y · Cited by 135

The effects of p53 on whole organism longevity are mediated by autophagy

Tavernarakis, N., Pasparaki, A., Tasdemir, E., Maiuri, M. C., & Kroemer, G. (2008) · Autophagy · doi:10.4161/auto.6730 · Cited by 132

Epigenetic Control of Autophagy: Nuclear Events Gain More Attention

Baek, S. H., & Kim, K. I. (2017) · Molecular Cell · doi:10.1016/j.molcel.2016.12.027 · Cited by 132

C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels

Beckers, J., Tharkeshwar, A. K., & Damme, P. V. (2021) · Autophagy · doi:10.1080/15548627.2021.1872189 · Cited by 132

Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

Kubat, G. B., Bouhamida, E., Ülger, Ö., Türkel, İ., Pedriali, G., Ramaccini, D., Ekinci, Ö., Özerkliğ, B., Atalay, Ö., Patergnani, S., et al. (2023) · Mitochondrion · doi:10.1016/j.mito.2023.07.003 · Cited by 134

Natural compounds with anti-ageing activity

Argyropoulou, A., Aligiannis, N., Trougakos, I. P., & Skaltsounis, A. (2013) · Natural Product Reports · doi:10.1039/c3np70031c · Cited by 132

Autophagy deregulation in neurodegenerative diseases – recent advances and future perspectives

Cheung, Z. H., & Ip, N. Y. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07314.x · Cited by 131

Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability

Bharath, L. P., Mueller, R., Li, Y., Ruan, T., Kunz, D., Goodrich, R., Mills, T. J., Deeter, L., Sargsyan, A., Babu, P. V. A., et al. (2014) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2014-0017 · Cited by 131

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease

Pilsl, A., & Winklhofer, K. F. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0902-3 · Cited by 131

Genetic Variants in MicroRNA Biosynthesis Pathways and Binding Sites Modify Ovarian Cancer Risk, Survival, and Treatment Response

Liang, D., Meyer, L. A., Chang, D. W., Lin, J. M., Pu, X., Ye, Y., Gu, J. H., Wu, X., & Lu, K. H. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0130 · Cited by 131

Autophagy - An Emerging Anti-Aging Mechanism?

Hansen, M. (2012) · Journal of Clinical & Experimental Pathology · doi:10.4172/2161-0681.s4-006 · Cited by 131

Autophagy and bacterial infectious diseases

Yuk, J., Yoshimori, T., & Jo, E. (2012) · Experimental & Molecular Medicine · doi:10.3858/emm.2012.44.2.032 · Cited by 131

Carbon Monoxide Activates Autophagy via Mitochondrial Reactive Oxygen Species Formation

Lee, S., Ryter, S. W., Xu, J., Nakahira, K., Kim, H. P., Choi, A. M. K., & Kim, Y. S. (2011) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2010-0352oc · Cited by 131

NLRP3 Inflammasome in Acute Myocardial Infarction

Mauro, A. G., Bonaventura, A., Mezzaroma, E., Quader, M. A., & Toldo, S. A. (2019) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000717 · Cited by 131

Atg1 family kinases in autophagy initiation

Noda, N. N., & Fujioka, Y. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1917-z · Cited by 132

BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

Castillo, K., Rojas‐Rivera, D., Lisbona, F., Caballero, B., Nassif, M., Court, F. A., Schuck, S., Ibar, C., Walter, P., Sierralta, J. A., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.318 · Cited by 130

Assessment of the Lung Toxicity of Copper Oxide Nanoparticles: Current Status

Ahamed, M., Akhtar, M. J., Alhadlaq, H. A., & Alrokayan, S. (2015) · Nanomedicine · doi:10.2217/nnm.15.72 · Cited by 130

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

Lee, S., Kim, H.-P., Jin, Y., Choi, A. M. K., & Ryter, S. W. (2011) · Autophagy · doi:10.4161/auto.7.8.15598 · Cited by 130

Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia

Lee, J., & Gao, F. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0924-09.2009 · Cited by 130

The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation

Lao, Y., Wan, G., Liu, Z., Wang, X., Ruan, P., Xu, W., Xu, D., Xie, W., Zhang, Y., Xu, H., et al. (2014) · Autophagy · doi:10.4161/auto.28034 · Cited by 130

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

Fujita, N., Saitoh, T., Kageyama, S., Akira, S., Noda, T., & Yoshimori, T. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.037671 · Cited by 130

p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins

Yu, H., Su, J., Xu, Y., Kang, J., Li, H., Zhang, L., Yi, H., Xiang, X., Liu, F., & Sun, L. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.01.019 · Cited by 130

Mechanisms of neuronal homeostasis: Autophagy in the axon

Maday, S. (2016) · Brain Research · doi:10.1016/j.brainres.2016.03.047 · Cited by 130

Selective endosomal microautophagy is starvation-inducible inDrosophila

Mukherjee, A., Patel, B., Koga, H., Cuervo, A. M., & Jenny, A. (2016) · Autophagy · doi:10.1080/15548627.2016.1208887 · Cited by 133

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

Zhang, Z.-H., Wu, Q., Zheng, R., Chen, C., Chen, Y., Liu, Q., Hoffmann, P. R., Ni, J., & Song, G.-L. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3229-16.2017 · Cited by 130

Vitamin K2 stimulates Mc3T3‑E1 osteoblast differentiation and mineralization through autophagy induction

Li, W., Zhang, S., Liu, J., Liu, Y., & Liang, Q. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10040 · Cited by 130

Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis

Cui, Y., Yang, S., Wei, J., Shea, C. R., Zhong, W., Wang, F., Shah, P., Kibriya, M. G., Cui, X., Ahsan, H., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22469-6 · Cited by 132

Ceramide induced mitophagy and tumor suppression

Dany, M., & Öğretmen, B. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.12.039 · Cited by 130

Autophagy inhibition enhances apigenin-induced apoptosis in human breast cancer cells.

Cao, X., Liu, B., Cao, W., Zhang, W., Zhang, F., Zhao, H., Meng, R., Zhang, L., Niu, R., Hao, X., et al. (2013) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.1000-9604.2013.04.01 · Cited by 129

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

Li, B.-H., Yin, Y.-W., Liu, Y., Pi, Y., Guo, L., Cao, X.-J., Gao, C.-Y., Zhang, L.-L., & Li, J.-C. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.146 · Cited by 129

Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells

Bao, L., Jaramillo, M. C., Zhang, Z., Zheng, Y., Yao, M., ZHANG, D. D., & Yi, X. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2671 · Cited by 129

Shaping development with ESCRTs

Rusten, T. E., Vaccari, T., & Stenmark, H. (2011) · Nature Cell Biology · doi:10.1038/ncb2381 · Cited by 129

Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

Martino, L., Masini, M., Novelli, M., Beffy, P., Bugliani, M., Marselli, L., Masiello, P., Marchetti, P., & Tata, V. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036188 · Cited by 129

Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells

Zhao, X., Fang, Y., Yang, Y., Yu, Q., Wu, P., Wang, T., Lai, H., Li, M., Wang, D. W., Zheng, Z., et al. (2015) · Autophagy · doi:10.1080/15548627.2015.1017185 · Cited by 130

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

Bejarano, E., Girão, H., Yuste, A., Patel, B., Marques, C., Spray, D. C., Pereira, P., & Cuervo, A. M. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-10-0844 · Cited by 129

The autophagy pathway participates in resistance to tomato yellow leaf curl virus infection in whiteflies

Wang, L., Wang, X., Wei, X., Huang, H., Wu, J., Chen, X., Liu, S., & Wang, X. (2016) · Autophagy · doi:10.1080/15548627.2016.1192749 · Cited by 129

Profiling IgG N-glycans as potential biomarker of chronological and biological ages

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Natural and trained innate immunity against Mycobacterium tuberculosis

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