The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.
The development of allergic inflammation
Open accessAbstract
Allergic disorders, such as anaphylaxis, hay fever, eczema and asthma, now afflict roughly 25% of people in the developed world. In allergic subjects, persistent or repetitive exposure to allergens, which typically are intrinsically innocuous substances common in the environment, results in chronic allergic inflammation. This in turn produces long-term changes in the structure of the affected organs and substantial abnormalities in their function. It is therefore important to understand the characteristics and consequences of acute and chronic allergic inflammation, and in particular to explore how mast cells can contribute to several features of this maladaptive pattern of immunological reactivity.
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“Overall, we recognise that these kinds of inflammatory, oxidative stress-related reactions are accumulative and somewhat irreversible [161], that they are consequently age-related, and (see [162-165] and later), and that most diseases and causes of mortality that are prevalent in the developed world are in this sense largely manifestations of this kind of aging.”
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Cites
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MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances
Galli, S. J., Kalesnikoff, J., Grimbaldeston, M. A., Piliponsky, A. M., Williams, C. M. M., & Tsai, M. M. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141025 · Cited by 1,259
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Research works printed but not linked: 1
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Cited by
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Nathan, C., & Ding, A. (2010) · Cell · doi:10.1016/j.cell.2010.02.029 · Cited by 2,183
IgE and mast cells in allergic disease
Galli, S. J., & Tsai, M. (2012) · Nature Medicine · doi:10.1038/nm.2755 · Cited by 1,799
Self-citationMetabolic regulation of immune responses
Ganeshan, K., & Chawla, A. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120236 · Cited by 926
New developments in mast cell biology
Kalesnikoff, J., & Galli, S. J. (2008) · Nature Immunology · doi:10.1038/ni.f.216 · Cited by 750
Self-citationThe spectrum of inflammatory responses
Medzhitov, R. (2021) · Science · doi:10.1126/science.abi5200 · Cited by 718
Metadata
- Authors
- Galli, S. J., Tsai, M., & Piliponsky, A. M.
- Affiliations
- Stanford Medicine (US)
- Venue
- Nature
- Published
- 2008-07-01
- Volume
- 454
- Issue
- 7203
- Pages
- 445-454
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3573758
- OpenAlex
- W2007589345
- Cited by
- 1,839
- References
- 102
- Citations by year
- 2026: 75 · 2025: 80 · 2024: 100 · 2023: 127 · 2022: 117 · 2021: 113 · 2020: 133 · 2019: 125 · 2018: 97 · 2017: 101 · 2016: 102 · 2015: 94 · 2014: 124 · 2013: 106 · 2012: 95
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- National Institutes of Health
- National Cancer Institute (R01CA072074)
- National Institute of Allergy and Infectious Diseases (R01AI023990, R01AI070813)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Keywords
- allergic inflammation, mast cells, anaphylaxis, allergic rhinitis, atopic dermatitis, asthma, allergen exposure, chronic inflammation, hypersensitivity
- MeSH terms
- Allergens, Animals, Chronic Disease, Epithelium, Humans, Hypersensitivity, Immunoglobulin E, Inflammation
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