An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L., & Shay, J. W. (1994) · Science · doi:10.1126/science.7605428 · Cited by 7,091

Creation of human tumour cells with defined genetic elements

Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W., & Weinberg, R. A. (1999) · Nature · doi:10.1038/22780 · Cited by 2,345

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., & Cech, T. R. (1997) · Science · doi:10.1126/science.277.5328.955 · Cited by 2,256

A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline

Vagin, V. V., Sigova, A. A., Li, C., Seitz, H., Gvozdev, V. A., & Zamore, P. D. (2006) · Science · doi:10.1126/science.1129333 · Cited by 1,385

On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing

Sijen, T., Fleenor, J., Simmer, F., Thijssen, K. L., Parrish, S., Timmons, L., Plasterk, R. H. A., & Fire, A. Z. (2001) · Cell · doi:10.1016/s0092-8674(01)00576-1 · Cited by 1,287

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

Watanabe, T., Totoki, Y., Toyoda, A., Kaneda, M., Kuramochi‐Miyagawa, S., Obata, Y., Chiba, H., Kohara, Y., Kono, T., Nakano, T., et al. (2008) · Nature · doi:10.1038/nature06908 · Cited by 1,147

Arabidopsis SGS2 and SGS3 Genes Are Required for Posttranscriptional Gene Silencing and Natural Virus Resistance

Mourrain, P., Béclin, C., Elmayan, T., Feuerbach, F., Godon, C., Morel, J., Jouette, D., Lacombe, A.-M., Nikic, S., Picault, N., et al. (2000) · Cell · doi:10.1016/s0092-8674(00)80863-6 · Cited by 1,098

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

Tam, O. H., Aravin, A. A., Stein, P., Girard, A., Murchison, E. P., Cheloufi, S., Hodges, E. C., Anger, M., Sachidanandam, R., Schultz, R. M., et al. (2008) · Nature · doi:10.1038/nature06904 · Cited by 1,042

Inhibition of telomerase limits the growth of human cancer cells

Hahn, W. C., Stewart, S. A., Brooks, M. W., York, S. G., Eaton, E. N., Kurachi, A. L., Beijersbergen, R. L., Knoll, J. H. M., Meyerson, M. M., & Weinberg, R. A. (1999) · Nature Medicine · doi:10.1038/13495 · Cited by 1,038

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

Weinrich, S. L., Pruzan, R., Ma, L., Ouellette, M. M., Tesmer, V. M., Holt, S. E., Bodnar, A. G., Lichtsteiner, S., Kim, N. W., Trager, J. B., et al. (1997) · Nature Genetics · doi:10.1038/ng1297-498 · Cited by 975

Telomere Biology in Stem Cells and Reprogramming

Batista, L. F. Z. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-397898-1.00003-7 · Cited by 22

Defects in lymphocyte telomere homeostasis contribute to cellular immune phenotype in patients with cartilage-hair hypoplasia

Aubert, G., Strauss, K. A., Lansdorp, P. M., & Rider, N. L. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.11.051 · Cited by 20

Human Fibroblasts In Vitro Exposed to 2.45 GHz Continuous and Pulsed Wave Signals: Evaluation of Biological Effects with a Multimethodological Approach

Regalbuto, E., Anselmo, A., Sanctis, S. D., Franchini, V., Lista, F., Benvenuto, M., Bei, R., Masuelli, L., d'Inzeo, G., Paffi, A., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197069 · Cited by 20

Telomerase in hematologic malignancies

Bruedigam, C., & Lane, S. (2016) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000252 · Cited by 20

The soft genome

Anava, S., Posner, R., & Rechavi, O. (2014) · Worm · doi:10.4161/21624054.2014.989798 · Cited by 17

Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell‐based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase activation therapies

Babizhayev, M. A., & Yegorov, Y. E. (2015) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35515 · Cited by 20

Role for Telomerase in Listeria monocytogenes Infection

Samba‐Louaka, A., Stavru, F., & Cossart, P. (2012) · Infection and Immunity · doi:10.1128/iai.00614-12 · Cited by 22

Novel Stress-Inducible Antisense RNAs of Protein-Coding Loci Are Synthesized by RNA-Dependent RNA Polymerase

Matsui, A., Iida, K., Tanaka, M., Yamaguchi, K., Mizuhashi, K., Kim, J.-M., Takahashi, S., Kobayashi, N., Shigenobu, S., Shinozaki, K., et al. (2017) · PLANT PHYSIOLOGY · doi:10.1104/pp.17.00787 · Cited by 19

Inflammatory factor receptor Toll‐like receptor 4 controls telomeres through heterochromatin protein 1 isoforms in liver cancer stem cell

Zheng, Q., Xu, J., Lin, Z., Lu, Y., Xin, X., Li, X., Yang, Y., Meng, Q., Wang, C., Xiong, W., et al. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13606 · Cited by 19

Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression

Zhang, B., Ling, T., Zhaxi, P., Cao, Y. Q., Qian, L., Zhao, D., Kang, W., Zhang, W., Wang, L., Xu, G., et al. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.03.029 · Cited by 19

Single Cell Analysis of RNA-mediated Histone H3.3 Recruitment to a Cytomegalovirus Promoter-regulated Transcription Site

Newhart, A., Rafalska-Metcalf, I. U., Yang, T., Joo, L. M., Powers, S. L., Kossenkov, A. V., Lopez-Jones, M., Singer, R. H., Showe, L. C., Skordalakes, E., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.473181 · Cited by 21

Evolution of TERT-interacting lncRNAs: expanding the regulatory landscape of telomerase

Nelson, A. D. L., & Shippen, D. E. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00277 · Cited by 19

Telomerase Variant A279T Induces Telomere Dysfunction and Inhibits Non-Canonical Telomerase Activity in Esophageal Carcinomas

Zhang, Y., Calado, R. T., Rao, M., Hong, J. A., Meeker, A. K., Dumitriu, B., Atay, S. M., McCormick, P. J., Garfield, S. H., Wangsa, D., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101010 · Cited by 18

Mass spectrometry-based assay for the molecular diagnosis of glioma: concomitant detection of chromosome 1p/19q codeletion, and IDH1, IDH2, and TERT mutation status

Pesenti, C., Paganini, L., Fontana, L., Veniani, E., Runza, L., Ferrero, S., Bòsari, S., Menghi, M., Marfia, G., Caroli, M., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.19103 · Cited by 19

Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma

Li, Y., Li, M., Yao, G., Geng, N., Xie, Y., Feng, Y., Zhang, P., Kong, X. L., Xue, J., Cheng, S., et al. (2011) · Cancer Gene Therapy · doi:10.1038/cgt.2010.81 · Cited by 18

Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics

Melicher, D., Buzás, E. I., & Falus, A. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1991-2 · Cited by 17

Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming

Kinoshita, T., Nagamatsu, G., Saito, S., Takubo, K., Horimoto, K., & Suda, T. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.536037 · Cited by 19

The search for endogenous siRNAs in the mammalian brain

Smalheiser, N. R. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.015 · Cited by 19

In Vitro Activities of the Multifunctional RNA Silencing Polymerase QDE-1 of Neurospora crassa*

Aalto, A. P., Poranen, M. M., Grimes, J. M., Stuart, D. I., & Bamford, D. H. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.139121 · Cited by 18

Clinical Medicine Insights: Blood Disorders

(2016) · Clinical Medicine Insights Blood Disorders · doi:10.4137/cmbd · Cited by 17

Dynamics of telomeric chromatin at the crossroads of aging and cancer

Ye, J., Wu, Y., & Gilson, É. (2010) · Essays in Biochemistry · doi:10.1042/bse0480147 · Cited by 15

Inflammatory related gene IKKα, IKKβ, IKKγ cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis

An, J., Wu, M., Xin, X., Lin, Z., Li, X., Zheng, Q., Gui, X., Li, T., Pu, H., Li, H., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.10321 · Cited by 16

Silencing of TERT decreases levels of miR‐1, miR‐21, miR‐29a and miR‐208a in cardiomyocytes

Drevytska, T., Nagibin, V. S., Gurianova, V. L., Kedlian, V. R., Moibenko, A. A., & Dosenko, V. (2014) · Cell Biochemistry and Function · doi:10.1002/cbf.3051 · Cited by 16

Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells

Maida, Y., Kyo, S., Lassmann, T., Hayashizaki, Y., & Masutomi, K. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14059305 · Cited by 16

Epigenetic Regulation of Telomere Maintenance

Fojtová, M., & Fajkus, J. (2014) · Cytogenetic and Genome Research · doi:10.1159/000360775 · Cited by 16

Portrait of replication stress viewed from telomeres

Ishikawa, F. (2013) · Cancer Science · doi:10.1111/cas.12165 · Cited by 18

Long Non-Coding RNAs as Regulators for Targeting Breast Cancer Stem Cells and Tumor Immune Microenvironment: Biological Properties and Therapeutic Potential

Yang, F., Yang, Y. L., Qiu, Y., Tang, L., Xie, L., & Guan, X. (2024) · Cancers · doi:10.3390/cancers16020290 · Cited by 15

Leishmania major Telomerase TERT Protein Has a Nuclear/Mitochondrial Eclipsed Distribution That Is Affected by Oxidative Stress

Morillo, R. C., Lozano, I., Figarella, K., Osuna, A., & Ramírez, J. L. (2014) · Infection and Immunity · doi:10.1128/iai.02269-14 · Cited by 17

Global Identification of New Substrates for the Yeast Endoribonuclease, RNase Mitochondrial RNA Processing (MRP)

Aulds, J., Wierzbicki, S., McNairn, A. J., & Schmitt, M. E. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.389023 · Cited by 15

Exercise, telomerase activity, and cardiovascular disease prevention

Stellos, K., & Spyridopoulos, I. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy707 · Cited by 18

A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium

Nassir, N., Hyde, G. J., & Baskar, R. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008188 · Cited by 14

Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members.

Jin, Y., You, L., Kim, H. J., & Lee, H. (2018) · Europe PMC (PubMed Central) · doi:10.14348/molcells.2018.0206 · Cited by 14

The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells

Yukimoto, A., Watanabe, T., Sunago, K., Nakamura, Y., Tanaka, T., Koizumi, Y., Yoshida, O., Tokumoto, Y., Hirooka, M., Abe, M., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-86592-6 · Cited by 14

LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206

Huang, Y., Xie, B., Cao, M., Lu, H., Wu, X., Hao, Q., & Zhou, X. Y. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.730538 · Cited by 14

Telomerase is required for glomerular renewal in kidneys of adult mice

Montandon, M., Hamidouche, T., Yart, L., Duret, L. C., Pons, C., Soubeiran, N., Pousse, M., Cervera, L., Vial, V., Fassy, J., et al. (2022) · npj Regenerative Medicine · doi:10.1038/s41536-022-00212-z · Cited by 16

Origin of an endogenous bornavirus-like nucleoprotein element in thirteen-lined ground squirrels

Suzuki, Y., Kobayashi, Y., Horie, M., & Tomonaga, K. (2014) · Genes & Genetic Systems · doi:10.1266/ggs.89.143 · Cited by 14

When the Ends Are Really the Beginnings: Targeting Telomerase for Treatment of GBM

Bollam, S., Berens, M. E., & Dhruv, H. (2018) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-018-0825-7 · Cited by 14

Chronic dysfunction of Stromal interaction molecule by pulsed RNAi induction in fat tissue impairs organismal energy homeostasis in Drosophila

Xu, Y., Borcherding, A. F., Heier, C., Gu, T., Roeder, T., & Kühnlein, R. P. (2019) · Scientific Reports · doi:10.1038/s41598-019-43327-y · Cited by 13

The code of non-coding RNAs in lung fibrosis

Cui, H., Xie, N., Thannickal, V. J., & Liu, G. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1939-6 · Cited by 14

SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma

Suzuki, K., Tange, M., Yamagishi, R., Hanada, H., Mukai, S., Sato, T., Tanaka, T., Akashi, T., Kadomatsu, K., Maeda, T., et al. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-01232-w · Cited by 13

TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential

Mishima, M., Takai, A., Takeda, H., Iguchi, E., Nakano, S., Fujii, Y., Ueno, M., Ito, T., Teramura, M., Eso, Y., et al. (2024) · The Journal of Pathology · doi:10.1002/path.6351 · Cited by 15

Telomeres and the nucleus

Novo, C. L., & Londoño‐Vallejo, A. (2012) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2012.02.001 · Cited by 14

The dichotomy of p53 regulation by noncoding RNAs

Deng, Q., Becker, L., Ma, X., Zhong, X., Young, K. H., Ramos, K. S., & Li, Y. (2014) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mju017 · Cited by 14

Class-Specific Prediction of ncRNAs

Stadler, P. F. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-709-9_10 · Cited by 13

Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs

Matsuda, Y., Yamashita, T., Ye, J., Yasukawa, M., Yamakawa, K., Mukai, Y., Machitani, M., Daigo, Y., Miyagi, Y., Yokose, T., et al. (2022) · The Journal of Pathology · doi:10.1002/path.5876 · Cited by 13

The Dictyostelium discoideum RNA-dependent RNA polymerase RrpC silences the centromeric retrotransposon DIRS-1 post-transcriptionally and is required for the spreading of RNA silencing signals

Wiegand, S., Meier, D., Seehafer, C., Malicki, M., Hofmann, P., Schmith, A., Winckler, T., Földesi, B., Boesler, B., Nellen, W., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1337 · Cited by 14

Genome-wide impact of endogenous antisense transcripts in eukaryotes

Numata, K. (2011) · Frontiers in bioscience · doi:10.2741/3928 · Cited by 14

Cyclin-dependent kinase 1 (CDK1) in cancers: from upstream regulation to downstream substrates and therapeutic inhibitors

Chen, X., Wang, X., Wang, J., Nie, X., Ji, J., Liu, X., Tian, H., & Li, C. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.118090 · Cited by 12

Foetal presentation of cartilage hair hypoplasia with extensive granulomatous inflammation

Crahès, M., Saugier-Véber, P., Patrier, S., Aziz, M., Pirot, N., Brasseur‐Daudruy, M., Layet, V., Frébourg, T., & Laquerrière, A. (2013) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2013.04.004 · Cited by 12

Novel insights into roles of N6-methyladenosine reader YTHDF2 in cancer progression

Liu, R., Jia, Y., Kong, G., & He, A. (2022) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-022-04134-7 · Cited by 12

Retrotransposon‐derived p53 binding sites enhance telomere maintenance and genome protection

Lieberman, P. M. (2016) · BioEssays · doi:10.1002/bies.201600078 · Cited by 12

Telomere - A Complex End of a Chromosome

Larramendy, M. L. (2016) · InTech eBooks · doi:10.5772/60625 · Cited by 12

Surprises from the Chromosome Front: Lessons from Arabidopsis on Telomeres and TelomerasePreprint

Nelson, A. D. L., & Shippen, D. E. (2012) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2013.77.017053 · Cited by 11

Genome Replication I: the Players

Rozovics, J. M., & Semler, B. L. (2014) · ASM Press eBooks · doi:10.1128/9781555816698.ch7 · Cited by 11

Saccharomyces cerevisiae as a model for the study of extranuclear functions of mammalian telomerase

Šimoničová, L., Dudekova, H., Ferenc, J., Procházková, K., Neboháčová, M., Dušinský, R., Nosek, J., & Tomáška, Ľ. (2015) · Current Genetics · doi:10.1007/s00294-014-0472-8 · Cited by 12

Treatment of cartilage–hair hypoplasia with recombinant human growth hormone

Obara-Moszyńska, M., Wielanowska, W., Rojek, A., Wolnik-Brzozowska, D., & Niedziela, M. (2013) · Pediatrics International · doi:10.1111/ped.12215 · Cited by 11

Cost-Effective Trap qPCR Approach to Evaluate Telomerase Activity: an Important Tool for Aging, Cancer, and Chronic Disease Research

Pinto, T. N. C., Fernandes, J. R., Arruda, L. B., Duarte, A. J. D. S., & Benard, G. (2021) · Clinics · doi:10.6061/clinics/2021/e2432 · Cited by 12

An infant with cartilage-hair hypoplasia due to a novel homozygous mutation in the promoter region of theRMRP gene associated with chondrodysplasia and severe immunodeficiency

Vatanavicharn, N., Visitsunthorn, N., Pho‐iam, T., Jirapongsananuruk, O., Pacharn, P., Chokephaibulkit, K., Limwongse, C., & Wasant, P. (2010) · Journal of Applied Genetics · doi:10.1007/bf03208884 · Cited by 11

Overlapping mechanisms of lncRNA and expanded microsatellite RNA

Johnson, S. J., & Cooper, T. A. (2020) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1634 · Cited by 11

The making of an organ

Rassoulzadegan, M., & Cuzin, F. (2010) · Organogenesis · doi:10.4161/org.6.1.11094 · Cited by 10

Eribulin prolongs survival in an orthotopic xenograft mouse model of malignant meningioma

Nakano, T., Fujimoto, K., Tomiyama, A., Takahashi, M., Achiha, T., Arita, H., Kawauchi, D., Yasukawa, M., Masutomi, K., Kondo, A., et al. (2021) · Cancer Science · doi:10.1111/cas.15221 · Cited by 9

TERT translocation to mitochondria: Exploring its role in mitochondrial homeostasis

Marinaccio, J., Rossi, E., Micheli, E., Udroiu, I., Baranzini, N., Marcolli, G., & Sgura, A. (2025) · PLoS Genetics · doi:10.1371/journal.pgen.1011923 · Cited by 11

Neuroinflammation driven by human immunodeficiency virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of neurogranin in vivo and in vitro

dos Reis, R. S., Wagner, M. C. E., McKenna, S., & Ayyavoo, V. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03102-x · Cited by 9

[Telomerase and telomere: their structure and dynamics in health and disease].

Gómez, D. L. M., Armando, R. G., Fariña, H. G., & Gomez, D. E. (2014) · PubMed · Cited by 9

RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex

Krehan, M., Heubeck, C., Menzel, N., Seibel, P., & Schön, A. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks476 · Cited by 9

Functional characterization of theDrosophila MRP(mitochondrial RNA processing) RNA gene

Schneider, M. D., Bains, A. K., Rajendra, T. K., Domiński, Z., Matera, A. G., & Simmonds, A. J. (2010) · RNA · doi:10.1261/rna.2227710 · Cited by 9

Expression of polycomb protein BMI-1 maintains the plasticity of basal bronchial epithelial cells

Torr, E., Heath, M., Mee, M., Shaw, D. E., Sharp, T. V., & Sayers, I. (2016) · Physiological Reports · doi:10.14814/phy2.12847 · Cited by 9

Examining transfer of TERT to mitochondria under oxidative stress

Burkatovskii, D., Bogorodskiy, A. O., Maslov, I., Moiseeva, O. V., Chuprov‐Netochin, R. N., Smirnova, E., Ilyinsky, N. S., Mishin, A., Leonov, S. V., Bueldt, G., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-75127-4 · Cited by 8

Evolutionarily conserved role of telomerase reverse transcriptase in programming the microenvironment via regulation of the cGAS–STING pathway

Akıncılar, S. C., Fidan, K., Kumar, N., Ng, Q. F., Majee, P., Wu, L., Han, D. J., Chan, C. H. T., Chua, J. Y. H., Idzham, K., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01706-w · Cited by 8

Immunohistochemical expression of human telomerase reverse transcriptase in oral cancer and precancer: A case–control study

Mishra, N., Tandon, N., Fatima, N., Srivastava, A., Lal, N., & Kumar, V. (2019) · Journal of Oral and Maxillofacial Pathology · doi:10.4103/jomfp.jomfp_133_18 · Cited by 8

Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity

Machitani, M., Nomura, A., Yamashita, T., Yasukawa, M., Ueki, S., Fujita, K.-I., Ueno, T., Yamashita, A., Tanzawa, Y., Watanabe, M., et al. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01427-6 · Cited by 10

Telomerase Activity Impacts on Epstein-Barr Virus Infection of AGS Cells

Rac, J., Florian, H., Andrina, S., Middeldorp, J. M., Delecluse, H., Speck, R. F., Bernasconi, M., & Nadal, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123645 · Cited by 8

Back to the future: The intimate and evolving connection between telomere-related factors and genotoxic stress

Barcenilla, B. B., & Shippen, D. E. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.aw119.008145 · Cited by 8

Expression of telomerase reverse transcriptase in peripheral T‐cell lymphoma

Arakawa, F., Miyoshi, H., Yoshida, N., Nakashima, K., Watatani, Y., Furuta, T., Yamada, K., Moritsubo, M., Takeuchi, M., Yanagida, E., et al. (2021) · Cancer Medicine · doi:10.1002/cam4.4200 · Cited by 7

The Canonical RNA Interference Pathway in Animals

Nejepinska, J., Flemr, M., & Svoboda, P. (2011) · Springer eBooks · doi:10.1007/978-3-642-22517-8_5 · Cited by 8

Annotating non-coding transcription using functional genomics strategies

Forrest, A. R. R., Abdelhamid, R. F., & Carninci, P. (2009) · Briefings in Functional Genomics and Proteomics · doi:10.1093/bfgp/elp041 · Cited by 8

Télomères : un Nobel pour le début de la fin

Rajpar, S., Guittat, L., & Mergny, J. (2011) · Bulletin du Cancer · doi:10.1684/bdc.2011.1378 · Cited by 9

Mobile DNA Elements: The Seeds of Organic Complexity on Earth

Habibi, L., Pedram, M., Amirfiroozi, A., & Bonyadi, K. (2015) · DNA and Cell Biology · doi:10.1089/dna.2015.2938 · Cited by 8

RNA Wave for the HIV Therapy: Foods, Stem Cells and the RNA Information Gene

Fujii, Y. R. (2013) · World Journal of AIDS · doi:10.4236/wja.2013.32018 · Cited by 6

Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT‐mediated transcriptional reprogramming

Xie, X., Li, M., Zhou, M., Chow, S. F., & Tsang, C. K. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15515 · Cited by 6

Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline

Graniel, J. V., Bisht, K. K., Friedman, A. D., White, J. S., Perkey, E., Vanderbeck, A., Moroz, A., Carrington, L. J., Brandstadter, J. D., Allen, F., et al. (2021) · Life Science Alliance · doi:10.26508/lsa.202101208 · Cited by 7

Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts

Chabronova, A., van den Akker, G., Steinbusch, M. M. F., Friedrich, F., Cremers, A., Surtel, D. A., Peffers, M. J., van Rhijn, L. W., Lausch, E. U., Zabel, B., et al. (2021) · Non-coding RNA Research · doi:10.1016/j.ncrna.2021.12.003 · Cited by 6

Intercompartment RNA Trafficking in Mitochondrial Function and Communication

Weber-Lotfi, F., & Dietrich, A. (2018) · Nucleic acids and molecular biology · doi:10.1007/978-3-319-78190-7_4 · Cited by 4

Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis

Ebata, H., Shima, T., Iizuka, R., & Uemura, S. (2023) · FEBS Open Bio · doi:10.1002/2211-5463.13682 · Cited by 7

Impact of mitochondrial telomerase over-expression on drug resistance of hepatocellular carcinoma.

Yan, J., Zhou, Y., Chen, D., Li, L., Yang, X., You, Y., & Ling, X. (2015) · Europe PMC (PubMed Central) · Cited by 7

Intracellular Mis-Localization of Modified RNA Molecules and Non-Coding RNAs: Facts from Hematologic Malignancies

Symeonidis, A. S., Chroni, A., Dereki, I., Chartoumpekis, D. V., & Sgourou, A. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47090758 · Cited by 5

Synergy between virus and three kingdom pathogens, fungus, bacterium and virus is lost in rice mutant lines of OsRDR1/6

Wagh, S. G., Bhor, S. A., Miyao, A., Hirochika, H., Toriba, T., Hirano, H.-Y., Kobayashi, K., Yaeno, T., & Nishiguchi, M. (2024) · Plant Science · doi:10.1016/j.plantsci.2024.112244 · Cited by 5

Widespread association of ERα with RMRP and tRNA genes in MCF-7 cells and breast cancers

Malcolm, J. R., Leese, N. K., Lamond-Warner, P. I., Brackenbury, W. J., & White, R. J. (2022) · Gene · doi:10.1016/j.gene.2022.146280 · Cited by 5

Is RNA-dependent RNA polymerase essential for transposon control?

Crombach, A., & Hogeweg, P. (2011) · BMC Systems Biology · doi:10.1186/1752-0509-5-104 · Cited by 5

Nuclear translocation of telomerase reverse transcriptase is a critical process in lymphatic metastasis of nasopharyngeal carcinoma

Wu, T., Chen, C., Chen, S., Xu, Y. J., Wang, Y., Chen, Z., Wang, F., Xiao, B., & Tao, Z. (2014) · Oncology Letters · doi:10.3892/ol.2014.2689 · Cited by 5

The enigmatic RNase MRP of kinetoplastids

Rosenblad, M. A., López, M. D., & Samuelsson, T. (2021) · RNA Biology · doi:10.1080/15476286.2021.1952758 · Cited by 5

Repositioning anticancer drugs as novel COVID-19 antivirals: targeting structural and functional similarities between viral proteins and cancer

Low, Z. Y., Yip, A. J. W., & Lal, S. K. (2022) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.11 · Cited by 5

Convenient screening of the reproductive toxicity of favipiravir and antiviral drugs in Caenorhabditis elegans

Shiraki, K., Mishima, M., Sato, N., Imoto, Y., & Nishiwaki, K. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35331 · Cited by 4

Predicted Trans-Acting siRNAs in the Human Brain

Liu, X., Zhang, G., Zhang, C., & Wang, J. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16023377 · Cited by 4

Telomeres and Telomerase in Neuroblastoma

Hajj, J. E., Garsuault, D., Bouyer, C., Nguyen, É., Hilal, G., & Ségal-Bendirdjian, E. (2017) · InTech eBooks · doi:10.5772/intechopen.69567 · Cited by 4

Rid7C, a Member of the YjgF/YER057c/UK114 (Rid) Protein Family, Is a Novel Endoribonuclease That Regulates the Expression of a Specialist RNA Polymerase Involved in Differentiation in Nonomuraea gerenzanensis

Damiano, F., Calcagnile, M., Pasanisi, D., Talà, A., Tredici, S. M., Giannotti, L., Siculella, L., & Alifano, P. (2021) · Journal of Bacteriology · doi:10.1128/jb.00462-21 · Cited by 4

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein

Maida, Y., Yasukawa, M., Ghilotti, M., Ando, Y., & Masutomi, K. (2018) · Journal of Visualized Experiments · doi:10.3791/57021 · Cited by 4

Is CCDC26 a Novel Cancer-Associated Long-Chain Non-Coding RNA?

Hirano, T. (2013) · InTech eBooks · doi:10.5772/54996 · Cited by 4

How old are RNA Networks?

Daly, T. K., Chen, X. S., & Penny, D. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0332-6_17 · Cited by 4

Evidence for an RNA Polymerization Activity in Axolotl and Xenopus Egg Extracts

Pelczar, H., Woisard, A., Lemaı̂tre, J.-M., Chachou, M., & Andéol, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014411 · Cited by 4

An RNA dependent RNA polymerase formed by hTERT and the RNase MRP RNA

Maida, Y., Yasukawa, M., Furuuchi, M., Lassmann, T., Okamoto, N., Kasim, V., Hayashizaki, Y., & Hahn, W. C. (2015)

Abstract IA-23: TERT, senescence, and transformation

Maida, Y., Hayashizaki, Y., Masutomi, K., & Hahn, W. C. (2009) · Cancer Research · doi:10.1158/0008-5472.fbcr09-ia-23

De Novo RNA Synthesis by RNA-Dependent RNA Polymerase Activity of Telomerase Reverse Transcriptase

Maida, Y., Yasukawa, M., & Masutomi, K. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.01021-15 · Cited by 41

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein

Maida, Y., Yasukawa, M., Ghilotti, M., Ando, Y., & Masutomi, K. (2018) · Journal of Visualized Experiments · doi:10.3791/57021-v · Cited by 2

Mutational analysis and post-transcriptional modification of human telomerase RNA

Handl, S. (2015) · University of Vienna · doi:10.25365/thesis.36539