The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Chromatin remodelling during development
Open accessAbstract
New methods for the genome-wide analysis of chromatin are providing insight into its roles in development and their underlying mechanisms. Current studies indicate that chromatin is dynamic, with its structure and its histone modifications undergoing global changes during transitions in development and in response to extracellular cues. In addition to DNA methylation and histone modification, ATP-dependent enzymes that remodel chromatin are important controllers of chromatin structure and assembly, and are major contributors to the dynamic nature of chromatin. Evidence is emerging that these chromatin-remodelling enzymes have instructive and programmatic roles during development. Particularly intriguing are the findings that specialized assemblies of ATP-dependent remodellers are essential for establishing and maintaining pluripotent and multipotent states in cells.
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“However, it has been well established that chromatin remodelings also comprise ATP-dependent enzymes [83].”
From Revisiting Epigenetics Fundamentals and Its Biomedical Implications (2024) · cites this paper as [83]
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1 retracted
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Cited by
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Epigenetic modifications and human disease
Portela, A., & Esteller, M. (2010) · Nature Biotechnology · doi:10.1038/nbt.1685 · Cited by 2,938
Transcriptional Regulation and Its Misregulation in Disease
Lee, T. I., & Young, R. A. (2013) · Cell · doi:10.1016/j.cell.2013.02.014 · Cited by 1,676
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
Clapier, C. R., Iwasa, J., Cairns, B. R., & Peterson, C. L. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.26 · Cited by 1,305
Lessons from the Cancer Genome
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Control of the Embryonic Stem Cell State
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Metadata
- Authors
- Ho, L., & Crabtree, G. R.
- Affiliations
- Stanford Medicine (US)
- Venue
- Nature
- Published
- 2010-01
- Volume
- 463
- Issue
- 7280
- Pages
- 474-484
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3060774
- OpenAlex
- W1984249881
- Cited by
- 1,114
- References
- 105
- Citations by year
- 2026: 39 · 2025: 42 · 2024: 54 · 2023: 46 · 2022: 57 · 2021: 63 · 2020: 56 · 2019: 64 · 2018: 80 · 2017: 84 · 2016: 78 · 2015: 82 · 2014: 71 · 2013: 78 · 2012: 76
- FWCI
- 8.15
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R01NS046789)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD055391)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chromatin Remodeling and Cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Keywords
- chromatin remodeling, developmental regulation, histone modifications, DNA methylation, pluripotency, multipotency, chromatin structure, extracellular signalling
- MeSH terms
- Animals, DNA, DNA-Binding Proteins, Drosophila melanogaster, Humans, Nucleic Acid Conformation, Transcription Factors, Body Patterning, Drosophila Proteins, Chromatin Assembly and Disassembly, Genome-Wide Association Study, Mi-2 Nucleosome Remodeling and Deacetylase Complex
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