Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

Physiology and neurobiology of stress and adaptation: central role of the brain

McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898

Reconsidering anhedonia in depression: Lessons from translational neuroscience

Treadway, M. T., & Zald, D. H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.006 · Cited by 1,579

Astrocytes give rise to new neurons in the adult mammalian hippocampus

Seri, B., Garcı́a-Verdugo, J. M., McEwen, B. S., & Alvarez-Buylla, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-18-07153.2001 · Cited by 1,495

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression

David, D. J., Samuels, B. A., Rainer, Q., Wang, J.-W., Marsteller, D., Mendez, I., Drew, M., Craig, D. A., Guiard, B. P., Guilloux, J.-P., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.017 · Cited by 1,267

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

Garcia, A. D. R., Doan, N., Imura, T., Bush, T. G., & Sofroniew, M. V. (2004) · Nature Neuroscience · doi:10.1038/nn1340 · Cited by 1,019

Methods of Behavior Analysis in Neuroscience

(2008) · CRC Press eBooks · doi:10.1201/9780367802622 · Cited by 777

Stress and adult neurogenesis

Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701

Stress and Memory: Behavioral Effects and Neurobiological Mechanisms

Sandi, C., & Pinelo-Nava, M. T. (2007) · Neural Plasticity · doi:10.1155/2007/78970 · Cited by 611

Lovastatin Prevents Depressive Behaviors and Increased Hippocampal Neurogenesis in Streptozotocin-Induced Diabetic Mice

Tang, C., Yu, X., Zhang, H., Cao, Y., Yang, F., Lei-Mei, X., Sun, R., Ye, Z., Wang, Y.-X., & Jin, L. (2019) · Pharmacology · doi:10.1159/000503865 · Cited by 15

Therapeutic implications of hypothalamic-pituitaryadrenal-axis modulation in Alzheimer’s disease: A narrative review of pharmacological and lifestyle interventions

Watermeyer, T., Robb, C. E., Gregory, S., & Udeh‐Momoh, C. T. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2020.100877 · Cited by 15

miR-129-5p targets FEZ1/SCOC/ULK1/NBR1 complex to restore neuronal function in mice with post-stroke depression

Qinlin, F., Wang, B., Hu, L., Peixia, S., Lexing, X., Lijun, Y., & Qingwu, Y. (2022) · Bioengineered · doi:10.1080/21655979.2022.2059910 · Cited by 15

Neuroimmunomodulation in unipolar depression: a focus on chronobiology and chronotherapeutics

Eyre, H. A., & Baune, B. T. (2012) · Journal of Neural Transmission · doi:10.1007/s00702-012-0819-6 · Cited by 15

Neural Mechanisms of Exercise: Effects on Gut Miccrobiota and Depression

Yuan, T., Rocha, N., Paes, F., Arias-Carrión, Ó., Machado, S. E. D. C., & Filho, A. S. S. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527315666151111124729 · Cited by 15

Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Hutton, C. P., Lemon, J. A., Šakić, B., Rollo, C. D., Boreham, D. R., Fahnestock, M. L., Wojtowicz, J. M., & Becker, S. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170921 · Cited by 15

N-acetylcysteine as a mitochondrial enhancer: a new class of psychoactive drugs?

Fries, G. R., & Kapczinski, F. P. (2011) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462011000400003 · Cited by 15

Perineuronal net structure as a non-cellular mechanism contributing to affective state: A scoping review

Morphett, J., Whittaker, A. L., Reichelt, A. C., & Hutchinson, M. R. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105568 · Cited by 14

UDP-Glucose/P2Y14 Receptor Signaling Exacerbates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats

Kanamaru, H., Zhu, S., Dong, S., Takemoto, Y., Huang, L., Sherchan, P., Suzuki, H., Tang, J., & Zhang, J. H. (2024) · Stroke · doi:10.1161/strokeaha.123.044422 · Cited by 14

Hormonal Regulation of Hippocampal Neurogenesis: Implications for Depression and Exercise

Gheorghe, A., Qiu, W., & Galea, L. A. M. (2018) · Current topics in behavioral neurosciences · doi:10.1007/7854_2018_62 · Cited by 14

Lacosamide intake during pregnancy increases the incidence of foetal malformations and symptoms associated with schizophrenia in the offspring of mice

López‐Escobar, B., Fernández‐Torres, R., Vargas-López, V., Villar-Navarro, M., Rybkina, T., Rivas, E., Hernández-Viñas, A., Benito, C. Á. D. V., Caro‐Vega, J. M., Sánchez-Alcázar, J. A., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-64626-9 · Cited by 14

Epigenetic modulation: Research progress on histone acetylation levels in major depressive disorders

Meng, Y., Du, J., Liu, N., Qiang, Y., Xiao, L., Lan, X., Ma, L., Yang, J.-M., Yu, J., & Lu, G. (2022) · Journal of drug targeting · doi:10.1080/1061186x.2022.2125978 · Cited by 14

Circ‐Bnc2 alleviates neuroinflammation in LPS‐stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR‐497a‐5p/HECTD1 axis

Chen, Y., & Cao, P. (2023) · Brain and Behavior · doi:10.1002/brb3.2935 · Cited by 14

Regional Differences in Human Ependymal and Subventricular Zone Cytoarchitecture Are Unchanged in Neuropsychiatric Disease

Comte, I., Kotagiri, P., & Szele, F. G. (2012) · Developmental Neuroscience · doi:10.1159/000338600 · Cited by 14

Effects of Antipsychotics on Dentate Gyrus Stem Cell Proliferation and Survival in Animal Models: A Critical Update

Keilhoff, G., Fusar‐Poli, P., & Becker, A. (2012) · Neural Plasticity · doi:10.1155/2012/832757 · Cited by 14

A Modified Chinese Herbal Decoction (Kai-Xin-San) Promotes NGF-Induced Neuronal Differentiation in PC12 Cells via Up-Regulating Trk A Signaling

Yan, A. L., Wei, M., Gong, A. G. W., Song, P., Lou, J.-S., Bi, C. W. C., Xu, S. L., Xiong, A., Dong, T. T.-X., & Tsim, K. W. K. (2017) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2017.00118 · Cited by 14

Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis

Lim, S.-H., Shin, S., Kim, M., Kim, E. C., Lee, D. Y., Moon, J., Park, H.-Y., Ryu, Y., Kang, Y.-M., Kang, Y. J., et al. (2020) · Journal of Cell Science · doi:10.1242/jcs.243972 · Cited by 14

Antidepressant-induced vascular dynamics in the hippocampus of adult mouse brain

Mannari, T., Sawa, H., Furube, E., Fukushima, S., Nishikawa, K., Nakashimna, T., & Miyata, S. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1933-6 · Cited by 14

N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype

Zhang, L., Tang, W., Ouyang, Y.-N., Zhang, M., Li, R., Sun, L.-P., Liu, C., & Yu, H.-L. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176041 · Cited by 13

High cadmium exposure impairs adult hippocampal neurogenesis via disruption of store-operated calcium entry

Li, G., Sun, C., Zhu, L., Zeng, Y., Li, J., & Mei, Y. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117162 · Cited by 13

LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance

Moreno‐Fernández, R. D., Rosell‐Valle, C., Bacq, A., Zanoletti, O., Cifuentes, M., Pérez‐Martín, M., Gavito, A., Garcia‐Fernandez, M. I., Estivill‐Torrús, G., de Fonseca, F. R., et al. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107896 · Cited by 13

Common herbs for stress: The science and strategy of a botanical medicine approach to self-care

Burns, J. (2022) · Journal of Interprofessional Education & Practice · doi:10.1016/j.xjep.2022.100592 · Cited by 13

Anti-Inflammation Relieving Heart Dysfunction and Depressive Behaviors of Mice Under Myocardial Infarction and Chronic Stress

Zhang, L., Tao, S., Lu, N., Pan, R., & Liu, M. (2022) · Heart and Mind · doi:10.4103/hm.hm_9_22 · Cited by 13

Disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression

Chen, B., Yang, M., Zhong, X., Wang, Q., Zhou, H., Liu, M., Zhang, M., Hou, L., Wu, Z., Zhang, S., et al. (2023) · Psychological Medicine · doi:10.1017/s0033291722003786 · Cited by 13

Mediating Effects of Trait Anxiety and State Anxiety on the Effects of Physical Activity on Depressive Symptoms

Kikkawa, M., Shimura, A., Nakajima, K., Morishita, C., Honyashiki, M., Tamada, Y., Higashi, S., Ichiki, M., Inoue, T., & Masuya, J. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20075319 · Cited by 13

Functional heterogeneity of Wnt-responsive and Hedgehog-responsive neural stem cells in the murine adult hippocampus

Luo, X., Dai, M., Wang, M., Wang, X., & Guo, W. (2023) · Developmental Cell · doi:10.1016/j.devcel.2023.07.021 · Cited by 13

Psychological well-being of small enterprise employees: a multi-theoretical perspective

Tabala, A., Munene, J. C. K., Kagaari, J. R. K., Mafabi, S., & Kyogabiirwe, J. (2023) · International journal of organizational analysis · doi:10.1108/ijoa-03-2023-3673 · Cited by 13

Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells

Song, N., Boku, S., Nakagawa, S., Kato, A., Toda, H., Takamura, N., Omiya, Y., Kitaichi, Y., Inoue, T., & Koyama, T. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.03.006 · Cited by 13

A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells

Al-Mayyahi, R. S., Sterio, L. D., Connolly, J. B., Adams, C. F., Al-Tumah, W. A. G., Sen, J., Emes, R. D., Hart, S. R., & Chari, D. M. (2017) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2017.11.006 · Cited by 13

Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A

Ji, S., Ding, X., Ji, J., Wu, H., Sun, R., Li, X., Zhang, L., & Tian, Y. (2017) · Oncology Letters · doi:10.3892/ol.2017.7643 · Cited by 13

The Hippocampus as a Neural Link between Negative Affect and Vulnerability for Psychostimulant Relapse

Barr, J. L., Bray, B., & Forster, G. L. (2018) · InTech eBooks · doi:10.5772/intechopen.70854 · Cited by 13

Antidepressant but Not Prophylactic Ketamine Administration Alters Calretinin and Calbindin Expression in the Ventral Hippocampus

LaGamma, C. T., Tang, W. W., Morgan, A. A., McGowan, J. C., Brachman, R. A., & Denny, C. A. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00404 · Cited by 13

Korean red ginseng promotes hippocampal neurogenesis in mice

Kim, S.-T., Ryu, S., Jeon, H., Kim, H.-Y., & Koo, S. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.268905 · Cited by 13

Role of Excitatory Amino Acid Carrier 1 (EAAC1) in Neuronal Death and Neurogenesis After Ischemic Stroke

Lee, M., Ko, D. G., Hong, D. K., Lim, M. S., Choi, B. Y., & Suh, S. W. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165676 · Cited by 13

The C825T Polymorphism of the G-Protein β3 Gene as a Risk Factor for Depression: A Meta-Analysis

Fang, L., Zhou, C., Bai, S., Huang, C., Pan, J., Wang, L., Wang, X., Mao, Q., Sun, L., & Xie, P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132274 · Cited by 13

Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice

Zhao, L., Pan, Y., Peng, K., Wang, Z., Li, J., Li, D., Tong, C., Wang, Y., & Liang, G. (2015) · Journal of Molecular Endocrinology · doi:10.1530/jme-14-0268 · Cited by 13

Targeting the GABAB Receptor for the Treatment of Depression and Anxiety Disorders

Felice, D., O’Leary, O. F., & Cryan, J. F. (2016) · Springer eBooks · doi:10.1007/978-3-319-46044-4_12 · Cited by 13

Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress

Rodrigues, R. S., Moreira, J. B., Mateus, J. M., Barateiro, A., Paulo, S. L., Vaz, S. H., Lourenço, D. M., Ribeiro, F. F., Soares, R., Loureiro-Campos, E., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02877-0 · Cited by 12

Sex-specific and developmental effects of early life adversity on stress reactivity are rescued by postnatal knockdown of 5-HT1A autoreceptors

Dixon, R. S., Malave, L. B., Thompson, R., Wu, S. S., Li, Y., Sadik, N., & Anacker, C. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01999-9 · Cited by 12

Corticosterone-induced postpartum depression induces depression-like behavior and impairs hippocampal neurogenesis in adolescent offspring via HPA axis and BDNF-mTOR pathway

Xie, H., Jiang, Y., Zhang, X., Min, X.-R., Zeng, J., Chen, L., Zeng, N., & Liu, R. (2025) · Neurobiology of Stress · doi:10.1016/j.ynstr.2025.100708 · Cited by 12

A comprehensive pharmacology study reveals the molecular mechanisms underlying the antidepressant effects of Gastrodiae Rhizoma

Liu, P., Zhao, Z., Zhang, H., Xiao, C., Wang, M., Yang, C., Liu, Y., Wang, L., He, H., Ge, Y., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156761 · Cited by 12

New Neurons Maintain Efficient Stress Recovery

Opendak, M. M., & Gould, E. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.09.003 · Cited by 12

Running promotes spatial bias independently of adult neurogenesis

Snyder, J. S., Cahill, S. P., & Frankland, P. W. (2017) · Hippocampus · doi:10.1002/hipo.22737 · Cited by 12

Inflammatory Response, a Key Pathophysiological Mechanism of Obesity-Induced Depression

Shao, S., Liu, D.-Q., Zhang, B., & Huang, S.-M. (2020) · Mediators of Inflammation · doi:10.1155/2020/8893892 · Cited by 12

Inhibition of Hippocampal Neurogenesis Starting in Adolescence Increases Anxiodepressive Behaviors Amid Stress

Larivee, R., Johnson, N., Freedgood, N. R., Cameron, H. A., & Schoenfeld, T. J. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.940125 · Cited by 12

Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors

Zhang, Y., Feng, W., Wang, Z., Pang, Y., Jin, Y., Chen, S., Ding, S., Wang, T., Zou, Y., Sun, P. G., et al. (2023) · Lab Animal · doi:10.1038/s41684-022-01090-0 · Cited by 12

Adult-born granule cells modulate CA2 network activity during retrieval of developmental memories of the mother

Laham, B. J., Gore, I. R., Brown, C. J., & Gould, E. (2023) · eLife · doi:10.7554/elife.90600 · Cited by 13

An Effect of Chronic Negative Stress on Hippocampal Structures and Functional Connectivity in Patients with Depressive Disorder

Zhang, L., Zhang, Y., Guo, W., Ma, Q., Zhang, F., Li, K., & Yi, Q. (2024) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s460429 · Cited by 12

Activity-regulated gene expression in immature neurons in the dentate gyrus following re-exposure to a cocaine-paired environment

Barr, J. L., & Unterwald, E. M. (2014) · Hippocampus · doi:10.1002/hipo.22377 · Cited by 12

Cortisol levels and history of depression in acute coronary syndrome patients

Messerli‐Bürgy, N., Molloy, G. J., Wikman, A., Perkins-Porras, L., Randall, G., & Steptoe, A. (2012) · Psychological Medicine · doi:10.1017/s0033291711002959 · Cited by 12

Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice

Zhang, X., Wang, D., Pan, H., & Sun, B. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00212 · Cited by 12

Increased Axin expression enhances adult hippocampal neurogenesis and exerts an antidepressant effect

Chen, W.-W., Fu, W., Su, Y.-T., Fang, W., Fu, A. K. Y., & Ip, N. Y. (2019) · Scientific Reports · doi:10.1038/s41598-018-38103-3 · Cited by 12

Harnessing Neurogenesis and Neuroplasticity with Stem Cell Treatment for Addictive Disorders

Tsai, S., Liew, H., Li, H., Lin, S., & Chen, S.-Y. (2019) · Cell Transplantation · doi:10.1177/0963689719859299 · Cited by 12

Thymoquinone harbors protection against Concanavalin A‐induced behavior deficit in BALB/c mice model

Nazir, S., Farooq, R. K., Khan, H., Alam, T., & Javed, A. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13348 · Cited by 12

Neuroanatomical changes of the medial prefrontal cortex of male pups of Wistar rat after prenatal and postnatal noise stress

Teimouri, M., Heidari, M. H., Amini, A., Sadeghi, Y., Abdollahifar, M., Aliaghaei, A., Khavanin, A., Nadri, F., Danyali, S., & Sanchooli, T. (2020) · Acta Histochemica · doi:10.1016/j.acthis.2020.151589 · Cited by 12

Synergy of oxytocin and citalopram in modulating Itgb3/Chl1 interplay: Relevance to sensitivity to SSRI therapy

Stanić, D., Oved, K., Israel‐Elgali, I., Jukić, M. M., Batinić, B., Puškaš, N., Shomron, N., Gurwitz, D., & Pešić, V. (2021) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2021.105234 · Cited by 12

Sedentary Life and Reduced Mastication Impair Spatial Learning and Memory and Differentially Affect Dentate Gyrus Astrocyte Subtypes in the Aged Mice

Mendes, F. D. C. C. D. S., da Paixão, L. T. V. B., Diniz, D. G., Anthony, D. C., Brites, D. M. T. O., Diniz, C. W. P., & Sosthenes, M. C. K. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.632216 · Cited by 12

L-DOPA-Induced Neurogenesis in the Hippocampus Is Mediated Through GPR143, a Distinct Mechanism of Dopamine

Kasahara, Y., Masukawa, D., Kobayashi, K., Yamasaki, M., Watanabe, M., & Goshima, Y. (2021) · Stem Cells · doi:10.1093/stmcls/sxab013 · Cited by 12

NAD+ Modulates the Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells via Akt Signaling Pathway

Huang, X., Guo, H., Cheng, X., Zhang, J., Qu, W., Ding, Q., Sun, Q., Shu, Q., & Li, X. (2022) · Cells · doi:10.3390/cells11081283 · Cited by 12

Quetiapine effect on depressive-like behaviors, oxidative balance, and inflammation in serum of rats submitted to chronic stress

Grolli, R. E., Bertollo, A. G., Behenck, J. P., Borba, L. A., Plissari, M. E., Soares, S. J. B., Mânica, A., Joaquim, L. D. S., Petronilho, F. C., Quevedo, J., et al. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02406-8 · Cited by 12

Vortioxetine Improves Context Discrimination in Mice Through a Neurogenesis Independent Mechanism

Felice, D., Guilloux, J., Pehrson, A. L., Li, Y., Mendez‐David, I., Gardier, A. M., Sánchez, C., & David, D. J. P. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00204 · Cited by 12

Parallel Effects of Methamphetamine on Anxiety and CCL3 in Humans and a Genetic Mouse Model of High Methamphetamine Intake

Huckans, M. S., Wilhelm, C., Phillips, T. J., Huang, E., Hudson, R., & Loftis, J. M. (2017) · Neuropsychobiology · doi:10.1159/000485129 · Cited by 12

Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice

Aesöy, R., Muwonge, H., Nordhus, K. S., Sabir, M., Witsoe, S. L., Bjørnstad, R., Kopperud, R. K., Høivik, E. A., Døskeland, S. O., & Bakke, M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200935 · Cited by 12

α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis

Su, Y.-T., Lau, S., Ip, J. P. K., Cheung, K., Cheung, T. H., Fu, A. K. Y., & Ip, N. Y. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1903891116 · Cited by 12

Ca2+-Binding Protein 1 Regulates Hippocampal-dependent Memory and Synaptic Plasticity

Yang, T., Britt, J. K., Cintrón-Pérez, C. J., Vázquez‐Rosa, E., Tobin, K. V., Stalker, G., Hardie, J. B., Taugher, R. J., Wemmie, J. A., Pieper, A. A., et al. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.04.004 · Cited by 12

Sex-specific expression of distinct serotonin receptors mediates stress vulnerability of adult hippocampal neural stem cells in mice

Luo, Y., Bao, H., Crowther, A., Li, Y., Chen, Z.-K., Tart, D. S., Asrican, B., Zhang, L., & Song, J. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114140 · Cited by 11

Harnessing exercise for brain health: BDNF, neuroplasticity & well-being

Tutakhail, A., Diarra, F., Coudoré, F., Mendez‐David, I., & David, D. J. P. (2025) · L Encéphale · doi:10.1016/j.encep.2025.08.006 · Cited by 12

Functions of adiponectin signaling in regulating neural plasticity and its application as the therapeutic target to neurological and psychiatric diseases

Sun, L., & Liu, X. (2019) · Reviews in the Neurosciences · doi:10.1515/revneuro-2018-0062 · Cited by 11

Regulation of embryonic and adult neurogenesis by Ars2

Yu, Y., Andreu-Agulló, C., Liu, B. F., Barboza, L., Tóth, M., & Lai, E. C. (2020) · Development · doi:10.1242/dev.180018 · Cited by 11

Minocycline prevents depression‐like behavior in streptozotocin‐induced diabetic mice

Sakurai, M., Iwasa, R., Sakai, Y., & Morimoto, M. (2020) · Neuropathology · doi:10.1111/neup.12706 · Cited by 11

Effects of a multi-strain probiotic on hippocampal structure and function, cognition, and emotional well-being in healthy individuals: a double-blind randomised-controlled trial

Ascone, L., Forlim, C. G., Gallinat, J., & Kühn, S. (2022) · Psychological Medicine · doi:10.1017/s0033291722000988 · Cited by 11

Repetitive transcranial magnetic stimulation and fluoxetine reverse depressive-like behavior but with differential effects on Olig2-positive cells in chronically stressed mice

Ramírez-Rodríguez, G. B., Juan, D. M.-S., Rico-Becerra, A. I., Gonzalez-Olvera, J. J., & Reyes‐Galindo, V. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109567 · Cited by 11

Combination of Walnut Peptide and Casein Peptide alleviates anxiety and improves memory in anxiety mices

Li, Q., Jia, X., Zhong, Q., Zhong, Z., Wang, Y., Tang, C., Zhao, B., Feng, H., Hao, J., Zhao, Z., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1273531 · Cited by 11

Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression

Ma, Y., Qiao, Y., & Gao, X. (2024) · Neural Regeneration Research · doi:10.4103/1673-5374.392855 · Cited by 11

A Serum Pharmacochemistry and Network Pharmacology-based Approach to Study the Anti-depressant Effect of Chaihu-Shugan San

Deng, M., Yan, Y.-Z., Zhu, S., Zhou, K., Tan, S.-J., & Zeng, P. H. (2024) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/0113862073285198240322072301 · Cited by 11

Mechanism of N6-Methyladenosine Modification in the Pathogenesis of Depression

Xian, Z., Tian, L., Yao, Z., Cao, L., Jia, Z., & Li, G. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04614-6 · Cited by 11

Chemotherapy drug thioTEPA exacerbates stress-induced anhedonia and corticosteroid responses but not impairment of hippocampal cell proliferation in adult mice

Wilson, C. L., & Weber, E. T. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.08.046 · Cited by 11

Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice

Kusne, Y. N., Goldberg, E. L., Parker, S. S., Hapak, S. M., Maskaykina, I. Y., Chew, W. M., Limesand, K. H., Brooks, H. L., Price, T. J., Sanai, N., et al. (2013) · AGE · doi:10.1007/s11357-013-9572-5 · Cited by 11

Early Life Stress- and Sex-Dependent Effects on Hippocampal Neurogenesis

Lucassen, P. J., Kőrösi, A., Krugers, H. J., & Oomen, C. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802175-0.00013-9 · Cited by 11

β2-microglobulin induces depressive- and anxiety-like behaviors in rat

Zhang, P., Zeng, D., Yi, Y.-L., Tang, Y.-Y., Zou, W., Yang, X., Wang, C., & Tang, X. (2018) · PLoS ONE · doi:10.1371/journal.pone.0198027 · Cited by 12

Development of whole brain versus targeted dentate gyrus irradiation model to explain low to moderate doses of exposure effects in mice

Santos, M. D., Kereselidze, D., Gloaguen, C., Benadjaoud, M. A., Tack, K., Lestaevel, P., & Durand, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-35579-x · Cited by 11

Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice

Nishida, S., Araki, R., Baba, A., Asari, S., Tachibana, S., Nakajima, Y., Iwakumo, A., & Yabe, T. (2020) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2020.02.007 · Cited by 11

A history of juvenile mild malaria exacerbates chronic stress-evoked anxiety-like behavior, neuroinflammation, and decline of adult hippocampal neurogenesis in mice

Guha, S. K., Sarkar, I., Patgaonkar, M. S., Banerjee, S., Mukhopadhyay, S., Sharma, S., Pathak, S., & Vaidya, V. A. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577363 · Cited by 11

Anti‐stress effects of combined block of glucocorticoid and mineralocorticoid receptors in the paraventricular nucleus of the hypothalamus

Ding, H., Cui, S., Cui, X., Liu, Y., Hu, X., Zhao, H., Qin, Y., Kurban, N., & Zhang, Y. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15511 · Cited by 11

Kihito prevents corticosterone-induced brain dysfunctions in mice

Araki, R., Tachioka, H., Kita, A., Fujiwara, H., Toume, K., Matsumoto, K., & Yabe, T. (2021) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2021.05.002 · Cited by 11

The NOP antagonist BTRX-246040 increases stress resilience in mice without affecting adult neurogenesis in the hippocampus

da Silva, F. D., Neto, J. A., Sturaro, C., Guarino, A., Robert, C., Gavioli, E. C., Calò, G., Moulédous, L., & Ruzza, C. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109077 · Cited by 11

Introduction to Memory

Stark, S. M., & Stark, C. E. L. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-407794-2.00067-5 · Cited by 11

Perinatal exposure to methoxychlor enhances adult cognitive responses and hippocampal neurogenesis in mice

Martini, M., Calandreau, L., Jouhanneau, M., Mhaouty‐Kodja, S., & Keller, M. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00202 · Cited by 11

The Antidepressant-like Effects of Estrogen-mediated Ghrelin

Wang, P., Liu, C., Liu, L., Zhang, X., Ren, B., & Li, B. (2015) · Current Neuropharmacology · doi:10.2174/1570159x1304150831120650 · Cited by 11

Chronic pregabalin treatment decreases excitability of dentate gyrus and accelerates maturation of adult‐born granule cells

Lempel, A. A., Coll, L. F., Schinder, A. F., Uchitel, O. D., & Piriz, J. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13740 · Cited by 11

Empfehlungen für Diagnostik und Therapie der Depression im Alter: Therapy Recommendations for Diagnosis and Treatment of Depression in Old Age

Hatzinger, M., Hemmeter, U., Hirsbrunner, T., Holsboer-Trachsler, E., Leyhe, T., Mall, J.-F., Mosimann, U., Rach, N., Trächsel, N., & Savaskan, E. (2018) · Praxis · doi:10.1024/1661-8157/a002883 · Cited by 11

Are Nestin-positive cells responsive to stress?

Bornstein, S. R., Berger, I., & Steenblock, C. (2020) · Stress · doi:10.1080/10253890.2020.1766441 · Cited by 11

Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy

Ruiz, N., Otalora, L. F. P., Farrell, B., Cox, C. B., Ermolinsky, B. S., Garrido-Sanabria, E. R., & Nair, S. (2011) · Brain Research · doi:10.1016/j.brainres.2011.10.006 · Cited by 11

Establishment of insomnia model of chronic unpredictable stress in rats

Zhang, W., Zhang, X., Yan, D., Wang, G., Wang, Q., Ren, X., & Liu, T. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e18338 · Cited by 10

Nelumbo nucifera Petals Ameliorate Depressive-like Symptom and Cognitive Deficit in Unpredictable Chronic Mild Stress Mouse Model

Maneenet, J., Chotritthirong, Y., Omar, A. M., Choonong, R., Daodee, S., Monthakantirat, O., Khamphukdee, C., Pitiporn, S., Awale, S., Matsumoto, K., et al. (2024) · Nutrients · doi:10.3390/nu17010094 · Cited by 10

Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice

Liu, W., Cao, Y. W., Lin, Y., Tan, K. S., Zhao, H., Guo, H., & Tan, W. (2021) · Biology · doi:10.3390/biology10050404 · Cited by 10

Adult neural stem cells and neurogenesis are resilient to intermittent fasting

Gabarró‐Solanas, R., Davaatseren, A., Kleifeld, J., Kepčija, T., Köcher, T., Giralt, A., Crespo‐Enríquez, I., & Urbán, N. (2023) · EMBO Reports · doi:10.15252/embr.202357268 · Cited by 10

Urocortin 2 But Not Urocortin 3 Promotes the Synaptic Formation in Hipppocampal Neurons via Induction of NGF Production by Astrocytes

Zheng, Y., Zhang, Y.-M., & Ni, X. (2015) · Endocrinology · doi:10.1210/en.2015-1812 · Cited by 10

Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells

Shimozaki, K. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0432-6 · Cited by 10

Cannabinoids as Regulators of Neural Development and Adult Neurogenesis

Campos, A. C., Paraíso‐Luna, J., Fogaça, M. V., Guimarães, F. S., & Galve‐Roperh, I. (2017) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-319-49343-5_6 · Cited by 10

Adult Hippocampal Neurogenesis in Depression: Behavioral Implications and Regulation by the Stress System

Anacker, C. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_275 · Cited by 63

Adult Hippocampal Neurogenesis Protects From Chronic Stress Effects in Mice

Anacker, C., Luna, V. M., Shores, R., Stevens, G. S., & Hen, R. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.02.172

Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors

Hill, A. S., Sahay, A., & Hen, R. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.85 · Cited by 557

Increasing adult hippocampal neurogenesis in mice after exposure to unpredictable chronic mild stress may counteract some of the effects of stress

Čulig, L., Surget, A., Bourdey, M., Khemissi, W., Guisquet, A. L., Vogel, E., Sahay, A., Hen, R., & Belzung, C. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.09.009 · Cited by 76

Dissecting the role of adult hippocampal neurogenesis towards resilience versus susceptibility to stress-related mood disorders

Jones, K. L., Zhou, M., & Jhaveri, D. J. (2022) · npj Science of Learning · doi:10.1038/s41539-022-00133-y · Cited by 35