The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
The promise of induced pluripotent stem cells in research and therapy
Open accessAbstract
The field of stem-cell biology has been catapulted forward by the startling development of reprogramming technology. The ability to restore pluripotency to somatic cells through the ectopic co-expression of reprogramming factors has created powerful new opportunities for modelling human diseases and offers hope for personalized regenerative cell therapies. While the field is racing ahead, some researchers are pausing to evaluate whether induced pluripotent stem cells are indeed the true equivalents of embryonic stem cells and whether subtle differences between these types of cell might affect their research applications and therapeutic potential.
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Cites
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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
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Embryonic Stem Cell Lines Derived from Human Blastocysts
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Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
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A bivalent chromatin structure marks key developmental genes in embryonic stem cells
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Self-citationReprogramming of human somatic cells to pluripotency with defined factors
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Self-citationEpigenetic memory in induced pluripotent stem cells
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Cited by
Highly efficient Cas9-mediated transcriptional programming
Chavez, A., Scheiman, J., Vora, S., Pruitt, B. W., Tuttle, M., P R Iyer, E., Lin, S., Kiani, S., Guzman, C. D., Wiegand, D. J., et al. (2015) · Nature Methods · doi:10.1038/nmeth.3312 · Cited by 1,622
The role of regulatory variation in complex traits and disease
Albert, F. W., & Kruglyak, L. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3891 · Cited by 1,047
Biomedical Applications of Untethered Mobile Milli/Microrobots
Sitti, M., Ceylan, H., Hu, W., Giltinan, J., Turan, M., Yim, S., & Diller, E. (2015) · Proceedings of the IEEE · doi:10.1109/jproc.2014.2385105 · Cited by 893
Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming
Soufi, A., Garcia, M. F., Jaroszewicz, A., Osman, N., Pellegrini, M., & Zaret, K. S. (2015) · Cell · doi:10.1016/j.cell.2015.03.017 · Cited by 780
“Generating induced pluripotent stem (iPS) cells, using the OSKM factors, has proved to be highly valuable for research, with great potential for regenerative medicine (Robinton and Daley, 2012).”
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Metadata
- Authors
- Robinton, D. A., & Daley, G. Q.
- Venue
- Nature
- Published
- 2012-01
- Volume
- 481
- Issue
- 7381
- Pages
- 295-305
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2109460321
- Cited by
- 1,111
- References
- 98
- FWCI
- 57.51
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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