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The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche

Toledano, Hila, D’Alterio, Cecilia, Czech, Benjamin, Levine, Erel, Jones, D. Leanne·2012·Nature

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Crossref · 10.1038/nature11061

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  • Aging-associated transcriptional signatures affect non-coding RNAs, including a class of miRNAs (gero-miRs) that is associated with the aging process and influences lifespan by targeting components of longevity networks or by regulating stem cell behavior.

    “These aging-associated transcriptional signatures also affect non-coding RNAs, including a class of miRNAs (gero-miRs) that is associated with the aging process and influences lifespan by targeting components of longevity networks or by regulating stem cell behavior (Boulias and Horvitz, 2012; Toledano et al., 2012; Ugalde et al., 2011).”

    From The Hallmarks of Aging (2013) · cites this paper as Toledano et al., 2012

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Research works printed but not linked: 42

  1. Schofield, R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4, 7–25 (1978)
  2. Voog, J. & Jones, D. L. Stem cells and the Niche: a dynamic duo. Cell Stem Cell 6, 103–115 (2010) · DOI
  3. Fuller, M. T. in The Development of Drosophila Melanogaster (eds Bate, M. & Martinez-Arias, A. ) 71–147 (Cold Spring Harbor Laboratory Press, 1993)
  4. Buszczak, M. et al. The carnegie protein trap library: a versatile tool for Drosophila developmental studies. Genetics 175, 1505–1531 (2007) · DOI
  5. Fabrizio, J. J. et al. Imp (IGF-II mRNA-binding protein) is expressed during spermatogenesis in Drosophila melanogaster . Fly 2, 47–48 (2008) · DOI
  6. Yisraeli, J. K. VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins. Biol. Cell 97, 87–96 (2005) · DOI
  7. Brand, A. H., Manoukian, A. S. & Perrimon, N. Ectopic expression in Drosophila . Methods Cell Biol. 44, 635–654 (1994) · DOI
  8. Munro, T. P., Kwon, S., Schnapp, B. J. & St Johnston, D. A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP. J. Cell Biol. 172, 577–588 (2006) · DOI
  9. Nabel-Rosen, H., Dorevitch, N., Reuveny, A. & Volk, T. The balance between two isoforms of the Drosophila RNA-binding protein how controls tendon cell differentiation. Mol. Cell 4, 573–584 (1999) · DOI
  10. Hafner, M. et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141, 129–141 (2010) · DOI · Paper page
  11. Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I. & Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125, 1111–1124 (2006) · DOI
  12. Elcheva, I., Goswami, S., Noubissi, F. K. & Spiegelman, V. S. CRD-BP protects the coding region of βTrCP1 mRNA from miR-183-mediated degradation. Mol. Cell 35, 240–246 (2009) · DOI
  13. Czech, B. et al. An endogenous small interfering RNA pathway in Drosophila . Nature 453, 798–802 (2008) · DOI
  14. Lee, Y. S. et al. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117, 69–81 (2004) · DOI
  15. Carthew, R. W. & Sontheimer, E. J. Origins and mechanisms of miRNAs and siRNAs. Cell 136, 642–655 (2009) · DOI
  16. Golden, D. E., Gerbasi, V. R. & Sontheimer, E. J. An inside job for siRNAs. Mol. Cell 31, 309–312 (2008) · DOI
  17. Czech, B. et al. Hierarchical rules for Argonaute loading in Drosophila . Mol. Cell 36, 445–456 (2009) · DOI
  18. Geng, C. & Macdonald, P. M. Imp associates with squid and Hrp48 and contributes to localized expression of gurken in the oocyte. Mol. Cell. Biol. 26, 9508–9516 (2006) · DOI
  19. Wang, L. & Jones, D. L. The effects of aging on stem cell behavior in Drosophila . Exp. Gerontol. 46, 340–344 (2010) · DOI
  20. Boyerinas, B. et al. Identification of let-7-regulated oncofetal genes. Cancer Res. 68, 2587–2591 (2008) · DOI
  21. Nishino, J., Kim, I., Chada, K. & Morrison, S. J. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 135, 227–239 (2008) · DOI
  22. Zhao, C. et al. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl Acad. Sci. USA 107, 1876–1881 (2010) · DOI
  23. Chen, C. et al. Defining embryonic stem cell identity using differentiation-related microRNAs and their potential targets. Mamm. Genome 18, 316–327 (2007) · DOI
  24. Rybak, A., Fuchs, H., Smirnova, L., Brandt, C., Pohl, E. E., Nitsch, R. & Wulczyn, F. G. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nature Cell Biol. 10, 987–993 (2008) · DOI
  25. Melton, C., Judson, R. L. & Blelloch, R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463, 621–626 (2010) · DOI
  26. Iliopoulos, D., Hirsch, H. A. & Struhl, K. An epigenetic switch involving NF-κB, Lin28, let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 139, 693–706 (2009) · DOI · Paper page
  27. Boyerinas, B., Park, S. M., Hau, A., Murmann, A. E. & Peter, M. E. The role of let-7 in cell differentiation and cancer. Endocr Relat Cancer 17, F19–F36 (2010) · DOI
  28. Zhu, H. et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 147, 81–94 (2011) · DOI
  29. Li, X., Cassidy, J. J., Reinke, C. A., Fischboeck, S. & Carthew, R. W. A microRNA imparts robustness against environmental fluctuation during development. Cell 137, 273–282 (2009) · DOI · Paper page
  30. Boylan, K. L. et al. Motility screen identifies Drosophila IGF-II mRNA-binding protein–zipcode-binding protein acting in oogenesis and synaptogenesis. PLoS Genet. 4, e36 (2008) · DOI
  31. Kitadate, Y. et al. Boss/Sev signaling from germline to soma restricts germline-stem-cell-niche formation in the anterior region of Drosophila male gonads. Dev. Cell 13, 151–159 (2007) · DOI
  32. Sokol, N. S. et al. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev. 22, 1591–1596 (2008) · DOI
  33. Caldwell, J. C., Fineberg, S. K. & Eberl, D. F. reduced ocelli encodes the leucine rich repeat protein Pray For Elves in Drosophila melanogaster . Fly 1, 146–152 (2007) · DOI
  34. Hime, G. R., Brill, J. A. & Fuller, M. T. Assembly of ring canals in the male germ line from structural components of the contractile ring. J. Cell Sci. 109, 2779–2788 (1996) · DOI
  35. Harrison, D. A., McCoon, P. E., Binari, R., Gilman, M. & Perrimon, N. Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes Dev. 12, 3252–3263 (1998) · DOI
  36. Bailey, T. L. & Elkan, C. Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Int. Conf. Intell. Syst. Mol. Biol. 2, 28–36 (1994)
  37. Schmittgen, T. D. & Livak, K. J. Analyzing real-time PCR data by the comparative C T method. Nature Protocols 3, 1101–1108 (2008) · DOI · Paper page
  38. Min, K. J., Yamamoto, R., Buch, S., Pankratz, M. & Tatar, M. Drosophila lifespan control by dietary restriction independent of insulin-like signaling. Aging Cell 7, 199–206 (2008) · DOI
  39. Yuan, J. S., Reed, A., Chen, F. & Stewart, C. N., Jr Statistical analysis of real-time PCR data. BMC Bioinformatics 7, 85 (2006) · DOI
  40. Brennecke, J. et al. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila . Cell 128, 1089–1103 (2007) · DOI · Paper page
  41. Haley, B. & Zamore, P. D. Kinetic analysis of the RNAi enzyme complex. Nature Struct. Mol. Biol. 11, 599–606 (2004) · DOI · Paper page
  42. Haley, B., Foys, B. & Levine, M. Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila . Proc. Natl Acad. Sci. USA 107, 11435–11440 (2010) · DOI

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Metadata

Authors
Toledano, H., D’Alterio, C., Czech, B., Levine, E., & Jones, D. L.
Venue
Nature
Published
2012-05-23
Volume
485
Issue
7400
Pages
605-610
ISSN
  • 0028-0836
  • 1476-4687
Cited by
169
References
3
Language
en

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