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Focal Dorsal Hippocampal Nav1.1 Knock Down Alters Place Cell Temporal Coordination and Spatial Behavior

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Decreased Number and Expression of nNOS-Positive Interneurons in Basolateral Amygdala in Two Mouse Models of Autism

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A single early-life seizure results in long-term behavioral changes in the adult Fmr1 knockout mouse

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Full function of exon junction complex factor, Rbm8a, is critical for interneuron development

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Reduced susceptibility to induced seizures in the Neuroligin-3R451C mouse model of autism

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Genome-Wide Analyses of Working-Memory Ability: A Review

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The α4β2 nicotinic acetylcholine receptor modulates autism-like behavioral and motor abnormalities in pentylenetetrazol-kindled mice

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Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus

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Synaptopathology in autism spectrum disorders: Complex effects of synaptic genes on neural circuits

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Social experience and sex-dependent regulation of aggression in the lateral septum by extrasynaptic δGABAA receptors

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Glycogen synthase kinase-3: The missing link to aberrant circuit function in disorders of cognitive dysfunction?

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The DNA repair protein ATM as a target in autism spectrum disorder

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Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission

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Gastrodin Rescues Autistic-Like Phenotypes in Valproic Acid-Induced Animal Model

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ATPase Inhibitory Factor 1 Is Critical for Regulating Sevoflurane-Induced Microglial Inflammatory Responses and Caspase-3 Activation

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Do All Roads Lead to Rome? Genes Causing Dravet Syndrome and Dravet Syndrome-Like Phenotypes

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Perineuronal Nets Alterations Contribute to Stress-Induced Anxiety-Like Behavior

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Sudden Unexpected Death in Dravet Syndrome

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Genetic loss of diazepam binding inhibitor in mice impairs social interest

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Elevated Anxiety and Impaired Attention in Super-Smeller, Kv1.3 Knockout Mice

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Lateralized Decrease of Parvalbumin+ Cells in the Somatosensory Cortex of ASD Models Is Correlated with Unilateral Tactile Hypersensitivity

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Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome

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Clinical spectrum and the comorbidities of Dravet syndrome in Taiwan and the possible molecular mechanisms

Huang, C.-H., Hung, P.-L., Fan, P., Lin, K., Hsu, T., Chou, I., Ho, C., Chou, I., Lin, W., Lee, I., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-98517-4 · Cited by 18

nNOS in Erbb4-positive neurons regulates GABAergic transmission in mouse hippocampus

Wan, C., Xia, Y., Yan, J., Lin, W.-P., Yao, L., Zhang, M., Gaisler‐Salomon, I., Mei, L., Yin, D., & Chen, Y. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06557-1 · Cited by 18

Parvalbumin neurons mediate neurological phenotypes of anti-NMDAR encephalitis

Feng, Y.-F., Zeng, Z.-K., Ni, Y., Hu, Y., Yang, K., Cai, F., Zhou, Q., Chen, M., Zhu, X., Chen, S., et al. (2025) · Brain · doi:10.1093/brain/awae374 · Cited by 18

PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus

Dinday, M. T., Girskis, K. M., Lee, S., Baraban, S. C., & Hunt, R. F. (2017) · Scientific Reports · doi:10.1038/s41598-017-08809-x · Cited by 18

Disordered autonomic function during exposure to moderate heat or exercise in a mouse model of Dravet syndrome

Sahai, N., Bard, A. M., Devinsky, O., & Kalume, F. K. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105154 · Cited by 20

Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons

Eid, L., Lokmane, L., Raju, P. K., Tadoum, S. B. T., Jiang, X., Toulouse, K., Lupien‐Meilleur, A., Charron-Ligez, F., Toumi, A., Backer, S., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02742-y · Cited by 17

Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss

Cairns, J., Swanson, D., Yeung, J., Sinova, A., Chan, R., Potluri, P., Dickson, P. E., Mittleman, G., & Goldowitz, D. (2016) · The Cerebellum · doi:10.1007/s12311-015-0756-7 · Cited by 17

Comorbidities in Dravet Syndrome and Lennox–Gastaut Syndrome

Marchese, F., Cappelletti, S., Filippini, M., Guido, C. A., Passamonti, C., Pucci, B., Sole, M., & Striano, P. (2021) · SN Comprehensive Clinical Medicine · doi:10.1007/s42399-021-00989-y · Cited by 17

Chronic partial TrkB activation reduces seizures and mortality in a mouse model of Dravet syndrome

Gu, F., Parada, I., Yang, T., Longo, F. M., & Prince, D. A. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2022726119 · Cited by 17

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome

Mavashov, A., Brusel, M., Liu, J., Woytowicz, V., Bae, H., Chen, Y.-H., Dani, V. S., Cardenal‐Muñoz, E., Spinosa, V., Aibar, J. Á., et al. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1149391 · Cited by 17

Methylphenidate improves learning impairments and hyperthermia‐induced seizures caused by an S cn1a mutation

Ohmori, I., Kawakami, N., Liu, S., Wang, H., Miyazaki, I., Asanuma, M., Michiue, H., Matsui, H., Mashimo, T., & Ouchida, M. (2014) · Epilepsia · doi:10.1111/epi.12750 · Cited by 17

Brain (Hyper)Excitability Revealed by Optimal Electrical Stimulation of GABAergic Interneurons

Wendling, F., Gerber, U. R., Cosandier‐Rimélé, D., Nica, A., de Montigny, J., Raineteau, O., Kalitzin, S., Lopes, F. H. D. S., & Benquet, P. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.07.001 · Cited by 20

The Emergence of Network Activity Patterns in the Somatosensory Cortex – An Early Window to Autism Spectrum Disorders

Iannone, A. F., & García, N. V. D. M. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.04.005 · Cited by 19

Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome

Chuang, S.-H., Westenbroek, R. E., Stella, N., & Catterall, W. A. (2021) · Journal of Experimental Neurology · doi:10.33696/neurol.2.040 · Cited by 17

Prenatal GABAB Receptor Agonist Administration Corrects the Inheritance of Autism-Like Core Behaviors in Offspring of Mice Prenatally Exposed to Valproic Acid

Jiang, S., He, M., Xiao, L., Sun, Y., Ding, J., Li, W., Guo, B., Wang, L., Wang, Y., Gao, C., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.835993 · Cited by 19

The treatment of autism with low-dose phenytoin: a case report

Bird, P. D. (2015) · Journal of Medical Case Reports · doi:10.1186/1752-1947-9-8 · Cited by 17

Response Dissociation in Hierarchical Cortical Circuits: a Unique Feature of Autism Spectrum Disorder

Kolodny, T., Schallmo, M., Gerdts, J. A., Bernier, R., & Murray, S. O. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.2376-19.2020 · Cited by 17

An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome

Doorn, N., van Hugte, E., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Kasri, N. N., & van Putten, M. J. A. M. (2023) · Stem Cell Reports · doi:10.1016/j.stemcr.2023.06.003 · Cited by 16

Toward the use of novel alternative methods in epilepsy modeling and drug discovery

Sanz, C. M., Navarro, M. M., Diaz, D. C., Sánchez‐Elexpuru, G., & Donato, V. D. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1213969 · Cited by 16

Functional Investigation of a Neuronal Microcircuit in the CA1 Area of the Hippocampus Reveals Synaptic Dysfunction in Dravet Syndrome Mice

Almog, Y., Mavashov, A., Brusel, M., & Rubinstein, M. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.823640 · Cited by 16

Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism

Derieux, C., Léauté, A., Brugoux, A., Jaccaz, D., Terrier, C., Pin, J., Kniazeff, J., Merrer, J. L., & Becker, J. A. J. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01317-1 · Cited by 16

Impairments in social novelty recognition and spatial memory in mice with conditional deletion of Scn1a in parvalbumin-expressing cells

Tatsukawa, T., Ogiwara, I., Mazaki, E., Shimohata, A., & Yamakawa, K. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.01.009 · Cited by 47

Mouse with Nav1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment

Ito, S., Ogiwara, I., Yamada, K., Miyamoto, H., Hensch, T. K., Ōsawa, M., & Yamakawa, K. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.08.003 · Cited by 113

Neurodevelopmental defects in Dravet syndrome Scn1a+/− mice: Targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality

Pizzamiglio, L., Capitano, F., Rusina, E., Fossati, G., Menna, E., Léna, I., Antonucci, F., & Mantegazza, M. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106853 · Cited by 10

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations

Mora-Jimenez, L., Valencia, M., Sánchez-Carpintero, R., Tønnesen, J., Fadila, S., Rubinstein, M., González-Aparicio, M., Buñuales, M., Fernández-Pierola, E., Nicolás, M. J., et al. (2021) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2021.08.003 · Cited by 44

Temporal manipulation of the Scn1a gene reveals its essential role in adult brain function

Berardino, C. D., Mainardi, M., Brusco, S., Benvenuto, E., Broccoli, V., & Colasante, G. (2023) · Brain · doi:10.1093/brain/awad350 · Cited by 13