Rubenstein, John L. R.

Model of autism: increased ratio of excitation/inhibition in key neural systems

Rubenstein, J. L. R., & Merzenich, M. M. (2003) · Genes, Brain and Behavior

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 2,768

Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes

Anderson, S. A., Eisenstat, D. D., Shi, L., & Rubenstein, J. L. R. (1997) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 1,462

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Chao, H.-T., Chen, H., Samaco, R. C., Xue, M., Chahrour, M., Yoo, J., Neul, J. L., Gong, S., Lu, H.-C., Heintz, N., et al. (2010) · Nature

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,168

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders

Sohal, V. S., & Rubenstein, J. L. R. (2019) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 988

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum

Sussel, L., Marin, O., Kimura, S., & Rubenstein, J. L. R. (1999) · Development

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 873

Tbr1 regulates differentiation of the preplate and layer 6

Hevner, R. F., Shi, L., Justice, N., Hsueh, Y.-P., Sheng, M., Smiga, S., Bulfone, A., Goffinet, A. M., Campagnoni, A. T., & Rubenstein, J. L. R. (2001) · Neuron

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 857

New insights into the classification and nomenclature of cortical GABAergic interneurons

DeFelipe, J., López-Cruz, P. L., Benavides-Piccione, R., Bielza, C., Larrañaga, P., Anderson, S., Burkhalter, A., Cauli, B., Fairén, A., Feldmeyer, D., et al. (2013) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchCell Image Analysis Techniques

Cited by 833

Forebrain gene expression domains and the evolving prosomeric model

Puelles, L., & Rubenstein, J. L. R. (2003) · Trends in Neurosciences

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 734

The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus

Monory, K., Massa, F., Egertová, M., Eder, M., Blaudzun, H., Westenbroek, R., Kelsch, W., Jacob, W., Marsch, R., Ekker, M., et al. (2006) · Neuron

Cannabis and Cannabinoid ResearchEpilepsy research and treatment

Cited by 706

Patterning and plasticity of the cerebral cortex

Sur, M., & Rubenstein, J. L. R. (2005) · Science

Neurogenesis and neuroplasticity mechanismsNeural dynamics and brain function

Cited by 677

Autistic-like behaviour in Scn1a+/− mice and rescue by enhanced GABA-mediated neurotransmission

Han, S., Tai, C., Westenbroek, R. E., Yu, F. H., Cheah, C. S., Potter, G. B., Rubenstein, J. L., Scheuer, T., de la Iglesia, H. O., & Catterall, W. A. (2012) · Nature

Epilepsy research and treatmentGenetics and Neurodevelopmental Disorders

Cited by 643

Origins of Cortical Interneuron Subtypes

Xu, Q., Cobos, I., De La Cruz, E., Rubenstein, J. L., & Anderson, S. A. (2004) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 639

Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes

Flames, N., Pla, R., Gelman, D. M., Rubenstein, J. L. R., Puelles, L., & Marín, O. (2007) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 560

The Embryonic Vertebrate Forebrain: the Prosomeric Model

Rubenstein, J. L. R., Martinez, S., Shimamura, K., & Puelles, L. (1994) · Science

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 535

Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy

Cobos, I., Calcagnotto, M. E., Vilaythong, A. J., Thwin, M. T., Noebels, J. L., Baraban, S. C., & Rubenstein, J. L. R. (2005) · Nature Neuroscience

Epilepsy research and treatmentNeurogenesis and neuroplasticity mechanisms

Cited by 502

Autism as a disorder of neural information processing: Directions for research and targets for therapy

Belmonte, M. K., Cook, E. H., Anderson, G. M., Rubenstein, J. L. R., Greenough, W. T., Beckel-Mitchener, A., Courchesne, E., Boulanger, L. M., Powell, S. B., Levitt, P. R., et al. (2004) · Molecular Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 442

Sorting of Striatal and Cortical Interneurons Regulated by Semaphorin-Neuropilin Interactions

Marı́n, O., Yaron, A., Bagri, A., Tessier-Lavigne, M., & Rubenstein, J. L. R. (2001) · Science

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 433

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1

Flames, N., Long, J. E., Garratt, A. N., Fischer, T. M., Gassmann, M., Birchmeier, C., Lai, C., Rubenstein, J. L. R., & Marı́n, O. (2004) · Neuron

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

Cited by 431

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

Nord, A. S., Blow, M. J., Attanasio, C., Akiyama, J. A., Holt, A., Hosseini, R., Phouanenavong, S., Plajzer-Frick, I., Shoukry, M., Afzal, V., et al. (2013) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 375

Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain

Petryniak, M. A., Potter, G. B., Rowitch, D. H., & Rubenstein, J. L. R. (2007) · Neuron

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 371

Intrinsically determined cell death of developing cortical interneurons

Southwell, D. G., Paredes, M. F., Galvao, R. P., Jones, D. L., Froemke, R. C., Sebe, J. Y., Alfaro-Cervello, C., Tang, Y., Garcia-Verdugo, J. M., Rubenstein, J. L., et al. (2012) · Nature

Neurogenesis and neuroplasticity mechanismsCell death mechanisms and regulation

Cited by 365

Early Neocortical Regionalization in the Absence of Thalamic Innervation

Miyashita-Lin, E. M., Hevner, R., Wassarman, K. M., Martinez, S., & Rubenstein, J. L. R. (1999) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 349

Generation of pure GABAergic neurons by transcription factor programming

Yang, N., Chanda, S., Marro, S., Ng, Y.-H., Janas, J. A., Haag, D., Ang, C. E., Tang, Y., Flores, Q., Mall, M., et al. (2017) · Nature Methods

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 341

Specific deletion of Na V 1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

Cheah, C. S., Yu, F. H., Westenbroek, R. E., Kalume, F. K., Oakley, J. C., Potter, G. B., Rubenstein, J. L., & Catterall, W. A. (2012) · Proceedings of the National Academy of Sciences

Epilepsy research and treatmentIon channel regulation and function

Cited by 336