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eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2

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The γ-Protocadherins Interact Physically and Functionally with Neuroligin-2 to Negatively Regulate Inhibitory Synapse Density and Are Required for Normal Social Interaction

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Local Protein Translation and RNA Processing of Synaptic Proteins in Autism Spectrum Disorder

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Local Translation Across Neural Development: A Focus on Radial Glial Cells, Axons, and Synaptogenesis

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Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice

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Does treatment have an impact on incidence and risk factors for autism spectrum disorders in children with infantile spasms?

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System-based proteomic and metabonomic analysis of the Df(16)A+/− mouse identifies potential miR-185 targets and molecular pathway alterations

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Common Ribs of Inhibitory Synaptic Dysfunction in the Umbrella of Neurodevelopmental Disorders

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Haploinsufficiency of a Circadian Clock Gene Bmal1 (Arntl or Mop3) Causes Brain-Wide mTOR Hyperactivation and Autism-like Behavioral Phenotypes in Mice

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Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism

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Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson’s disease

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Microglial WNT5A supports dendritic spines maturation and neuronal firing

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Neuroplastin 65 modulates anxiety‐ and depression‐like behavior likely through adult hippocampal neurogenesis and central 5‐ HT activity

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Gene-based genome-wide association studies and meta-analyses of conotruncal heart defects

Sewda, A., Agopian, A. J., Goldmuntz, E., Hakonarson, H. H., Morrow, B. E., Taylor, D. M., & Mitchell, L. E. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219926 · Cited by 23

Comparative psychopharmacology of autism and psychotic-affective disorders suggests new targets for treatment

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mRNA Recruiting eIF4 Factors Involved in Protein Synthesis and Its Regulation

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Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range

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Towards Identification of Individual Etiologies by Resolving Genomic and Biological Conundrums in Patients with Autism Spectrum Disorders

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The epitranscriptome in modulating spatiotemporal RNA translation in neuronal post-synaptic function

Hussain, S., & Bashir, Z. I. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00420 · Cited by 22

Genetic and Environmental Contributions to Autism Spectrum Disorder Through Mechanistic Target of Rapamycin

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mTOR-Dependent Spine Dynamics in Autism

Chaudry, S., & Vasudevan, N. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.877609 · Cited by 23

MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation

Li, S., Chen, J., Li, X., bai, X., & Shi, D. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115781 · Cited by 22

Inactivation of mTor arrests bovine oocytes in the metaphase‐I stage, despite reversible inhibition of 4E‐BP1 phosphorylation

Mayer, S., Wrenzycki, C., & Tomek, W. (2014) · Molecular Reproduction and Development · doi:10.1002/mrd.22305 · Cited by 25

Translational control and autism-like behaviors

Gkogkas, C. G., & Sonenberg, N. (2013) · Cellular Logistics · doi:10.4161/cl.24551 · Cited by 22

Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex

Iezzi, D., Cáceres-Rodríguez, A., Strauss, B., Chavis, P., & Manzoni, O. J. (2024) · Biology of Sex Differences · doi:10.1186/s13293-024-00593-4 · Cited by 21

Present and future of developmental neuropsychopharmacology

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RNA sequencing of transformed lymphoblastoid cells from siblings discordant for autism spectrum disorders reveals transcriptomic and functional alterations: Evidence for sex‐specific effects

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Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting

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What Is Social about Autism? The Role of Allostasis-Driven Learning

Djerassi, M., Ophir, S., & Atzil, S. (2021) · Brain Sciences · doi:10.3390/brainsci11101269 · Cited by 22

Local mRNA translation and cytoskeletal reorganization: Mechanisms that tune neuronal responses

Triantopoulou, N., & Vidaki, M. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.949096 · Cited by 23

Stem Cells as a Good Tool to Investigate Dysregulated Biological Systems in Autism Spectrum Disorders

Griesi‐Oliveira, K., Sunaga, D. Y., Alvizi, L., Vadasz, E., & Passos‐Bueno, M. R. (2013) · Autism Research · doi:10.1002/aur.1296 · Cited by 20

Increasing our understanding of human cognition through the study of fragile X syndrome

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Structural dynamics control the MicroRNA maturation pathway

Dallaire, P., Tan, H., Szulwach, K. E., Ma, C. M., Jin, P., & Major, F. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw793 · Cited by 20

Sexual divergence in activity‐dependent neuroprotective protein impacting autism, schizophrenia, and A lzheimer's disease

Gozes, I. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23808 · Cited by 20

Prenatal exposure to valproic acid alters the development of excitability in the postnatal rat hippocampus

Fueta, Y., Sekino, Y., Yoshida, S., Kanda, Y., & Ueno, S. (2018) · NeuroToxicology · doi:10.1016/j.neuro.2018.01.001 · Cited by 20

Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons

Kawamura, A., & Nishiyama, M. (2023) · Communications Biology · doi:10.1038/s42003-023-04968-y · Cited by 20

Translational control and autism-like behaviors

Gkogkas, C. G., & Sonenberg, N. (2013) · Cellular Logistics · doi:10.4161/cl.24551 · Cited by 22

Exaggerated translation causes synaptic and behavioural aberrations associated with autism

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Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2

Aguilar‐Valles, A., Matta‐Camacho, E., Khoutorsky, A., Gkogkas, C. G., Nader, K., Lacaille, J., & Sonenberg, N. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4615-14.2015 · Cited by 62

Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2

Wiebe, S. A., Nagpal, A., Truong, V. T., Park, J., Skalecka, A., He, A. J., Gamache, K., Khoutorsky, A., Gantois, I., & Sonenberg, N. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1908126116 · Cited by 58

The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior

Wiebe, S. A., Meng, X. Q., Kim, S., Zhang, X., Lacaille, J., Aguilar‐Valles, A., & Sonenberg, N. (2020) · Molecular Autism · doi:10.1186/s13229-020-00394-7 · Cited by 18