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Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice

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Food reward depends on TLR4 activation in dopaminergic neurons

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Phasic Stimulation of Midbrain Dopamine Neuron Activity Reduces Salt Consumption

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Impact of Stress on Gamma Oscillations in the Rat Nucleus Accumbens During Spontaneous Social Interaction

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Expansion of a frontostriatal salience network in individuals with depressionPreprint

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Dysfunctional heteroreceptor complexes as novel targets for the treatment of major depressive and anxiety disorders

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Optogenetics and chemogenetics: key tools for modulating neural circuits in rodent models of depression

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Remarkably High Heterogeneous Electron Transfer Activity of Carbon-Nanotube-Supported Reduced Graphene Oxide

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The role of catecholamines in modulating responses to stress: Sex‐specific patterns, implications, and therapeutic potential for post‐traumatic stress disorder and opiate withdrawal

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Subthalamic Deep Brain Stimulation Affects Plasma Corticosterone Concentration and Peripheral Immunity Changes in Rat Model of Parkinson’s Disease

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Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience

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Novel antidepressant mechanism of hypericin: Role of connexin 43-based gap junctions

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Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling

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Of Mice, Men, and Microbial Opsins: How Optogenetics Can Help Hone Mouse Models of Mental Illness

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Latency to Reward Predicts Social Dominance in Rats: A Causal Role for the Dopaminergic Mesolimbic System

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α7 nicotinic receptor full agonist reverse basolateral amygdala hyperactivity and attenuation of dopaminergic neuron activity in rats exposed to chronic mild stress

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Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations

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Unlocking the Treasure Trove: From Genes to Schizophrenia Biology

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Rostrocaudal subregions of the ventral tegmental area are differentially impacted by chronic stress

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Optogenetics: A revolutionary approach for the study of depression

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Class A and C GPCR Dimers in Neurodegenerative Diseases

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Optofluidic laser sensor for the detection of dopamine

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Hidden variables in stress neurobiology research

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Translating depression biomarkers for improved targeted therapies

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Repeated Exposure of Adult Rats to Transient Oxidative Stress Induces Various Long-Lasting Alterations in Cognitive and Behavioral Functions

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Allosteric modulatory effects of SRI-20041 and SRI-30827 on cocaine and HIV-1 Tat protein binding to human dopamine transporter

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Fabrication and modification of implantable optrode arrays for in vivo optogenetic applications

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Dopamine sensing with robust carbon nanotube implanted polymer micropillar array electrodes fabricated by coupling micromolding and infiltration coating processes

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Improvement of Learning and Increase in Dopamine Level in the Frontal Cortex by Methylphenidate in Mice Lacking Dopamine Transporter

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HCN channel inhibitor induces ketamine-like rapid and sustained antidepressant effects in chronic social defeat stress model

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Instant noninvasive near-infrared deep brain stimulation using optoelectronic nanoparticles without genetic modification

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The Cerebral Lymphatic System: Function, Controversies, and Therapeutic Approaches for Central Nervous System Diseases

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Behavioral Engagement With Playable Objects Resolves Stress-Induced Adaptive Changes by Reshaping the Reward System

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CB2 Agonist GW842166x Protected against 6-OHDA-Induced Anxiogenic- and Depressive-Related Behaviors in Mice

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Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress

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cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement

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Lateral hypothalamus orexinergic projection to the medial prefrontal cortex modulates chronic stress-induced anhedonia but not anxiety and despair

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Optogenetics and synaptic plasticity

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Footshock‐induced plasticity of GABA B signalling in the lateral habenula requires dopamine and glucocorticoid receptors

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Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments

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Rapid anti‐depressant‐like effects of ketamine and other candidates: Molecular and cellular mechanisms

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Transcriptome Analysis of Alcohol Drinking in Non-Dependent and Dependent Mice Following Repeated Cycles of Forced Swim Stress Exposure

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Neuronal Nitric Oxide Synthase in Nucleus Accumbens Specifically Mediates Susceptibility to Social Defeat Stress through Cyclin-Dependent Kinase 5

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Optogenetic approaches for investigating neural pathways implicated in schizophrenia and related disorders

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Exendin-4 increases absence-like seizures and anxiety–depression-like behaviors in WAG/Rij rats

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Inactivation mode of sodium channels defines the different maximal firing rates of conventional versus atypical midbrain dopamine neurons

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Social Determinants of Inter-Individual Variability and Vulnerability: The Role of Dopamine

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How Sucrose Preference Is Gained and Lost: An In-Depth Analysis of Drinking Behavior during the Sucrose Preference Test in Mice

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Several behavioral traits relevant for alcoholism are controlled by ɣ2 subunit containing GABAA receptors on dopamine neurons in mice

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Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats

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The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches

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Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress–Induced Hypolocomotion

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Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice

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Inherent vulnerabilities in monoaminergic pathways predict the emergence of depressive impairments in an animal model of chronic epilepsy

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Diffusion tensor imaging of white matter in patients with prediabetes by trace‐based spatial statistics

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Light up your life: Optogenetics for depression?

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Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior

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Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states

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Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity

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Selective activation of D1 dopamine receptors exerts antidepressant-like activity in rats

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Changes in striatal dopamine transporters in bipolar disorder and valproate treatment

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The Aversion Function of the Limbic Dopaminergic Neurons and Their Roles in Functional Neurological Disorders

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Neuronal activities during palatable food consumption in the reward system of binge-like eating female rats

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Gestational Buprenorphine Exposure Disrupts Dopamine Neuron Activity and Related Behaviors in Adulthood

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Stressed and wired: The effects of stress on the VTA circuits underlying motivated behavior

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High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens

Yuen, J., Goyal, A., Rusheen, A. E., Kouzani, A. Z., Berk, M., Kim, J. H., Tye, S. J., Blaha, C. D., Bennet, K. E., Lee, K. H., et al. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1061578 · Cited by 16

Nitrogen‐containing heterocyclic compounds: A ray of hope in depression?

Choudhary, D., Kumar, B., & Kaur, R. (2024) · Chemical Biology & Drug Design · doi:10.1111/cbdd.14479 · Cited by 17

A Cocaine-Activated Ensemble Exerts Increased Control Over Behavior While Decreasing in Size

Thibeault, K. C., Leonard, M. Z., Kondev, V., Emerson, S. D., Bethi, R., López, A. J., Sens, J. P., Nabit, B. P., Elam, H. B., Winder, D. G., et al. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.06.008 · Cited by 18

Resting-state fMRI reveals altered functional connectivity associated with resilience and susceptibility to chronic social defeat stress in mouse brain

Lupinsky, D., Nasseef, M. T., Parent, C. I., Craig, K., Diorio, J. C., Zhang, T., & Meaney, M. J. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02897-2 · Cited by 21

Distinct Roles of GluA2-lacking AMPA Receptor Expression in Dopamine D1 or D2 Receptor Neurons in Animal Behavior

Shou, J., Tran, A., Snyder, N., Bleem, E., & Kim, S. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.12.002 · Cited by 16

Decreases in Cued Reward Seeking After Reward-Paired Inhibition of Mesolimbic Dopamine

Fischbach-Weiss, S., & Janak, P. H. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.04.035 · Cited by 18

Pharmacological and non-pharmacological interventions of depression after traumatic brain injury: A systematic review

Liu, Q., Li, R., Qu, W., Li, B., Yang, W., & Cui, R. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172775 · Cited by 17

Optogenetics in preclinical neuroscience and psychiatry research: recent insights and potential applications

Britt, J. P., McDevitt, R. A., & Reed, S. J. (2014) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s45896 · Cited by 17

Dopamine and Stress

Stanwood, G. D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813146-6.00009-6 · Cited by 21

Involvement of D2 receptor in the NAc in chronic unpredictable stress-induced depression-like behaviors

Qiao, H., Yang, S., Xu, C. S., Ma, X., & An, S.-C. (2019) · Stress · doi:10.1080/10253890.2019.1673361 · Cited by 17

Conditioned task-set competition: Neural mechanisms of emotional interference in depression

Stolicyn, A., Steele, J. D., & Seriès, P. (2016) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-016-0478-4 · Cited by 18

Prelimbic medial prefrontal cortex disruption during adolescence increases susceptibility to helpless behavior in adult rats

Uliana, D. L., Gomes, F. V., & Grace, A. A. (2020) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2020.04.004 · Cited by 19

Cinnamaldehyde prevents intergenerational effect of paternal depression in mice via regulating GR/miR-190b/BDNF pathway

Gao, Z.-Y., Chen, T.-Y., Yu, T.-T., Zhang, L.-P., Zhao, S.-J., Gu, X.-Y., Pan, Y., & Kong, L.-D. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00831-0 · Cited by 18

Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward

Abraham, A. D., Casello, S. M., Land, B. B., & Chavkin, C. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100005 · Cited by 15

Ru incorporation for boosting Co3O4 oxidase-like activity in dopamine colorimetric detection

Wen, F., Jiang, T., Liu, H., Su, J., Jiang, P., He, D., & Chen, Z. (2022) · Applied Surface Science · doi:10.1016/j.apsusc.2022.154434 · Cited by 16

Genetic Addiction Risk and Psychological Profiling Analyses for “Preaddiction” Severity Index

Blum, K., Han, D. C., Bowirrat, A., Downs, B. W., Bagchi, D., Thanos, P. K., Baron, D. A., Braverman, E. R., Dennen, C. A., Gupta, A., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12111772 · Cited by 19

Dorsal raphe dopaminergic neurons target CaMKII+ neurons in dorsal bed nucleus of the stria terminalis for mediating depression-related behaviors

Wang, W., Wang, D., Zhao, D., Xu, L., Jiang, S., Zhang, Y., Cui, M., Liu, J., Meng, F., Liu, C., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03093-6 · Cited by 16

Sex‐Specific Adaptations to VTA Circuits Following Subchronic Stress

Bouarab, C., Wynalda, M., Thompson, B. V., Khurana, A., Cody, C. R., Kisner, A., & Polter, A. M. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70153 · Cited by 18

A behavioral defect of temporal association memory in mice that partly lack dopamine reuptake transporter

Deng, S., Zhang, L., Zhu, T., Liu, Y., Zhang, H., Shen, Y., Li, W., & Li, F. (2015) · Scientific Reports · doi:10.1038/srep17461 · Cited by 15

Rhythms, Reward, and Blues: Consequences of Circadian Photoperiod on Affective and Reward Circuit Function

Siemann, J. K., Grueter, B. A., & McMahon, D. G. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.12.010 · Cited by 17

Predicting responses of neuromodulation and psychotherapies for major depressive disorder: A coordinate-based meta-analysis of functional magnetic resonance imaging studies

Mao, Y., Fan, L., Feng, C., & Dai, Z. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106120 · Cited by 15

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

Chaudhury, D., Walsh, J. J., Friedman, A. K., Juarez, B., Ku, S. M., Koo, J. W., Ferguson, D., Tsai, H.-C., Pomeranz, L., Christoffel, D. J., et al. (2013) · Nature · doi:10.1038/nature11713 · Cited by 1,156

Firing of Dopamine Neurons Regulates Depression

Geller, B. (2013) · Journal watch · doi:10.1056/jp201301070000005

Alterations and adaptation of ventral tegmental area dopaminergic neurons in animal models of depression

Kaufling, J. (2019) · Cell and Tissue Research · doi:10.1007/s00441-019-03007-9 · Cited by 62

Ventral tegmental area dopaminergic neurons mediate electroacupuncture relief of stress-induced depression in mice

Yang, L., Yu, X., Yang, Q., Zhu, G., Xu, W., Yu, S., Zhang, R., Lin, L., Yu, L., Li, M., et al. (2026) · Life Sciences · doi:10.1016/j.lfs.2026.124252

The Midbrain Dopaminergic System in Behavioral Models of Depression

Ivlieva, N. Y. (2025) · Neurochemical Journal · doi:10.1134/s1819712425700904