RETRACTED ARTICLE: A mechanism for the suppression of homologous recombination in G1 cells

Genome engineering using the CRISPR-Cas9 system

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A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

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Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

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Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity

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Inhibitors of DNA double-strand break repair at the crossroads of cancer therapy and genome editing

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Post-translational modification of factors involved in homologous recombination

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RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair

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PCNA-Ub polyubiquitination inhibits cell proliferation and induces cell-cycle checkpoints

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p53‐competent cells and p53‐deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity

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Modulation of proteasome activity by curcumin and didemethylcurcumin

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The roles of KLHL family members in human cancers.

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Exploring factors influencing choice of DNA double-strand break repair pathways

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Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells

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Age-associated deficient recruitment of 53BP1 in G1 cells directs DNA double-strand break repair to BRCA1/CtIP-mediated DNA-end resection

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Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors

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Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination

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HDAC Inhibitor Sodium Butyrate Attenuates the DNA Repair in Transformed but Not in Normal Fibroblasts

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Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells

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Dissecting the Keap1/Nrf2 pathway through proteomics

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Sharpening the ends for repair: mechanisms and regulation of DNA resection

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Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome Manipulation

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BRCA1: a key player at multiple stages of homologous recombination in DNA double-strand break repair

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Beta human papillomavirus 8E6 promotes alternative end joining

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Identification of novel potential homologous repair deficiency-associated genes in pancreatic adenocarcinoma via WGCNA coexpression network analysis and machine learning

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Balancing act: To be, or not to be ubiquitylated

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A meeting at risk: Unrepaired DSBs go for broke

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DNA damage response and neoantigens: A favorable target for triple-negative breast cancer immunotherapy and vaccine development

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Gene editing of the extra domain A positive fibronectin in various tumors, amplified the effects of CRISPR/Cas system on the inhibition of tumor progression

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Virus Infection Induces Keap1 Binding to Cytokine Genes, Which Recruits NF-κB p50 and G9a-GLP and Represses Cytokine Transcription

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Pharmacological methods to transcriptionally modulate double-strand break DNA repair

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RNA polymerase III directly participates in DNA homologous recombination

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Gross Chromosomal Rearrangement at Centromeres

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Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

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Emerging cellular and gene therapies for congenital anemias

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Eukaryotic DNA damage responses: Homologous recombination factors and ubiquitin modification

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KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

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Cell Cycle–Mediated Regulation of Secondary Ig Diversification

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Targeting homologous recombination repair in cancer

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Ubiquitin and the DNA double-strand break repair pathway

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Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites

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Gene Therapy for Paediatric Homozygous Familial Hypercholesterolaemia

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Putative Factors Interfering Cell Cycle Re-Entry in Alzheimer’s Disease: An Omics Study with Differential Expression Meta-Analytics and Co-Expression Profiling

Yuen, S. C., Lee, S. M., & Leung, S.-W. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215349 · Cited by 7

Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variantPreprint

Bazinet, A., Heath, J., Chong, A., Simo‐Cheyou, E. R., Worme, S. J., Rivera, B., Foulkes, W. D., Caplan, S. N., Johnson, N. A., Orthwein, A., et al. (2021) · Molecular Case Studies · doi:10.1101/mcs.a006090 · Cited by 7

RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer

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MDM2 antagonists promote CRISPR/Cas9-mediated precise genome editing in sheep primary cells

Li, Y., Lian, D., Wang, J., Zhao, Y., Li, Y., Liu, G., Wu, S., Deng, S., Du, X., & Lian, Z. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.12.020 · Cited by 6

Efficient and risk-reduced genome editing using double nicks enhanced by bacterial recombination factors in multiple species

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De novo pathogenic germline variant in PALB2 in a patient with pancreatic cancer

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The role and mechanism of long non‐coding RNAs in homologous recombination repair of radiation‐induced DNA damage

Yu, N., Qin, H., Zhang, F., Liu, T., Cao, K., Yang, Y., Chen, Y., & Cai, J. (2022) · The Journal of Gene Medicine · doi:10.1002/jgm.3470 · Cited by 7

Genome editing for blood disorders: state of the art and recent advances

Romito, M., Rai, R., Thrasher, A. J., & Cavazza, A. (2019) · Emerging Topics in Life Sciences · doi:10.1042/etls20180147 · Cited by 7

PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

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Insight into meiotic DNA end resection: Mechanisms and regulation

Kim, S., Alnaser, H. F., Keeney, S., & Murakami, H. (2025) · DNA repair · doi:10.1016/j.dnarep.2025.103886 · Cited by 5

USP11 deubiquitinates E-cadherin and maintains the luminal fate of mammary tumor cells to suppress breast cancer

Tao, Q., Bai, F., Zhang, S., Xu, Y., Wang, Y., Yuan, S., Liu, X., Du, Y., Peng, B., Zhu, W., et al. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107768 · Cited by 5

RAD52-mediated repair of DNA double-stranded breaks at inactive centromeres leads to subsequent apoptotic cell death

Maruta, G., MAEOKA, H., Tsunoda, T., Akiyoshi, K., Takagi, S., Shirasawa, S., & Ishikura, S. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae852 · Cited by 5

Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair

Jung, E. S., Kim, J. H., Chang, M., Hong, W., Quan, Z., Kim, S. H., You, S., Kim, D., Jang, J., Lee, S., et al. (2022) · Stem Cell Research · doi:10.1016/j.scr.2022.102664 · Cited by 5

PALB2 as a factor to predict the prognosis of patients with skull base chordoma

Xiong, Y., Li, M., Shen, Y., Ma, T., Bai, J., & Zhang, Y. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.996892 · Cited by 5

DNA strand breaks at centromeres: Friend or foe?

Graham, E., & Esashi, F. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.10.004 · Cited by 5

Suppressor mutations in Mecp2 -null mice reveal that the DNA damage response is key to Rett syndrome pathologyPreprint

Enikanolaiye, A., Ruston, J., Zeng, R., Taylor, C., Schrock, M., Buchovecky, C. M., Shendure, J., Acar, E. F., & Justice, M. J. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/810929 · Cited by 5

Genetic therapies for neurological diseases

Rahim, A. A., Kurian, M. A., Zhou, H., Ferguson, R., Tabrizi, S. J., Lignani, G., Aquilina, K., & Waddington, S. N. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100093 · Cited by 4

Targeted editing of the 21-hydroxylase locus confers durable therapeutic effect in a murine model of congenital adrenal hyperplasia

Graves, L. E., Viswanath, L., van Dijk, E. B., Zhu, E., Koyyalamudi, S. R., Wotton, T., Rosser, S. P. A., Srinivasan, S., Ginn, S. L., & Alexander, I. E. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.11.011 · Cited by 4

ATM Inhibition Enhances Knock-in Efficiency by Suppressing AAV-Induced Activation of Apoptotic Pathways

Natsagdorj, M., Hara, H., Uosaki, H., Nakahara, F., Inoue, M., & Hanazono, Y. (2026) · Communications Biology · doi:10.1038/s42003-026-09604-z · Cited by 4

Protein oxidation increases SAMHD1 binding ssDNA via its regulatory site

Simermeyer, T. L., Batalis, S., Rogers, L. C., Zalesak, O. J., & Hollis, T. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad447 · Cited by 4

Four novel BRCA variants found in Chinese hereditary breast cancer patients by next-generation sequencing

Liu, P., Zhuo, Z., Xie, F., Wang, S., & Zhao, X. T. (2021) · Clinica Chimica Acta · doi:10.1016/j.cca.2021.01.010 · Cited by 4

USP11 suppresses CHK1 activation by deubiquitinating CLASPIN

Zhao, H., Wang, Z., Zhu, M., Liao, J., & Xu, X. (2021) · Genome Instability & Disease · doi:10.1007/s42764-021-00034-1 · Cited by 4

A Validated Functional Analysis of Partner and Localizer of BRCA2 Missense Variants for Use in Clinical Variant Interpretation

Brnich, S. E., Arteaga, E. C., Wang, Y., Tan, X. M., & Berg, J. S. (2021) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2021.04.010 · Cited by 4

Transcription Factors, R-Loops and Deubiquitinating Enzymes: Emerging Targets in Myelodysplastic Syndromes and Acute Myeloid Leukemia

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Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions

Hovland, H. N., Mchaina, E. K., Høberg‐Vetti, H., Ariansen, S. L., Sjursen, W., Ghelue, M. V., Haukanes, B. I., Knappskog, P. M., Aukrust, I., & Ognedal, E. (2023) · Genes · doi:10.3390/genes14020262 · Cited by 4

The cell cycle flavours of repair

Zlotorynski, E. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2015.24 · Cited by 4

Fluorescent in vivo editing reporter (FIVER): A novel multispectral reporter of in vivo genome editingPreprint

Tennant, P. A., Foster, R. G., Dodd, D. O., Sou, I. F., McPhie, F., Younger, N. T., Murphy, L. C., Pearson, M. W., Vernay, B., Keighren, M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.14.200170 · Cited by 4

Post-cleavage target residence determines asymmetry in non-homologous end joining of Cas12a-induced DNA double strand breaks

Chen, R.-D., Yang, Y., Liu, K.-M., Hu, J.-Z., Feng, Y.-L., Yang, C., Jiang, R.-R., Liu, S.-C., Wang, Y., Han, P.-A., et al. (2025) · Genome biology · doi:10.1186/s13059-025-03567-w · Cited by 4

Advances in the relationship of immune checkpoint inhibitors and DNA damage repair

Liu, X., Wang, S., Lv, H., Chen, E., Yan, L., & Yu, J. (2025) · Current Research in Translational Medicine · doi:10.1016/j.retram.2025.103494 · Cited by 3

Sleeping Beauty Transposon Insertions into Nucleolar DNA by an Engineered Transposase Localized in the Nucleolus

Kovač, A., Miskey, C., & Ivics, Z. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914978 · Cited by 3

Genome editing for engineering stem cell-derived pancreatic β cells: recent trends and future perspectives

Jang, S., Shin, S., Jeong, Y., & Lim, D. (2023) · Organoid · doi:10.51335/organoid.2023.3.e16 · Cited by 3

Applications of CRISPR-Cas in Ageing Research

Haston, S., Pozzi, S., & González-Meljem, J. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-40955-5_11 · Cited by 3

The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling

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Lumbar discectomy: developing and implementing a day surgery protocol.

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Processes that Regulate the Ubiquitination of Chromatin and Chromatin-Associated Proteins

Hare, A. E., & Parvin, J. D. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.82567 · Cited by 3

Ubiquitin-specific proteases as targets for anticancer drug therapies

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A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editingPreprint

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Nonhomologous end joining—the importance of end tethering and beyondPreprint

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Gene-sized DNA insertion at genomic safe harbors in human cells using a site-directed transposase

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Efficient in vivo labeling of endogenous proteins with SMART delineates retina cellular and synaptic organization

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Structural basis of CSN-mediated SCF deneddylation

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Altered cell cycle regulation in the development of resistance

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BRCA1 and BRCA2 Mutations - Diagnostic and Therapeutic Implications

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Delivering Base Editors In Vivo by Adeno-Associated Virus Vectors

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Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

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The cell cycle flavours of repair

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Recent Advances in In Vivo Genome Editing Targeting Mammalian Preimplantation Embryos

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Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein

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Rad51 inhibition sensitizes non-replicating quiescent cells to UVB radiation and transcription stressPreprint

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Engineering recombination machinery facilitates the construction of yeast cell factories

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The Roles of Cullin RING Ligases and the Anaphase Promoting Complex/Cyclosome in the Regulation of DNA Double Strand Break Repair

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Cell-Cycle Regulation of BRCA1 Inhibits Homologous Recombination in G1

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The cell cycle flavours of repair

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Abstract 2113: Elucidating mechanisms of regulation of homologous recombination utilizing a PALB2 fusion protein that contains the BRCT repeats of BRCA1

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Abstract 2471: Role of PALB2-BRCA1 interaction in tumor suppression

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Understanding the role of the PALB2-BRCA1 interaction in tumor suppression

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